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Items: 24

1.

Human induced pluripotent stem cell-derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis.

Povero D, Pinatel EM, Leszczynska A, Goyal NP, Nishio T, Kim J, Kneiber D, de Araujo Horcel L, Eguchi A, Ordonez PM, Kisseleva T, Feldstein AE.

JCI Insight. 2019 Jun 11;5. pii: 125652. doi: 10.1172/jci.insight.125652.

2.

Emricasan, a pan-caspase inhibitor, improves survival and portal hypertension in a murine model of common bile-duct ligation.

Eguchi A, Koyama Y, Wree A, Johnson CD, Nakamura R, Povero D, Kneiber D, Tameda M, Contreras P, Spada A, Feldstein AE.

J Mol Med (Berl). 2018 Jun;96(6):575-583. doi: 10.1007/s00109-018-1642-9. Epub 2018 May 5.

3.

Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis.

Cabrera D, Wree A, Povero D, Solís N, Hernandez A, Pizarro M, Moshage H, Torres J, Feldstein AE, Cabello-Verrugio C, Brandan E, Barrera F, Arab JP, Arrese M.

Sci Rep. 2017 Jun 14;7(1):3491. doi: 10.1038/s41598-017-03675-z.

4.

Microvesicles released from fat-laden cells promote activation of hepatocellular NLRP3 inflammasome: A pro-inflammatory link between lipotoxicity and non-alcoholic steatohepatitis.

Cannito S, Morello E, Bocca C, Foglia B, Benetti E, Novo E, Chiazza F, Rogazzo M, Fantozzi R, Povero D, Sutti S, Bugianesi E, Feldstein AE, Albano E, Collino M, Parola M.

PLoS One. 2017 Mar 1;12(3):e0172575. doi: 10.1371/journal.pone.0172575. eCollection 2017.

5.

Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood.

Eguchi A, Lazaro RG, Wang J, Kim J, Povero D, Willliams B, Ho SB, Stärkel P, Schnabl B, Ohno-Machado L, Tsukamoto H, Feldstein AE.

Hepatology. 2017 Feb;65(2):475-490. doi: 10.1002/hep.28838. Epub 2016 Nov 10.

6.

Novel Molecular Mechanisms in the Development of Non-Alcoholic Steatohepatitis.

Povero D, Feldstein AE.

Diabetes Metab J. 2016 Feb;40(1):1-11. doi: 10.4093/dmj.2016.40.1.1. Review.

7.

Lipid-induced hepatocyte-derived extracellular vesicles regulate hepatic stellate cell via microRNAs targeting PPAR-γ.

Povero D, Panera N, Eguchi A, Johnson CD, Papouchado BG, de Araujo Horcel L, Pinatel EM, Alisi A, Nobili V, Feldstein AE.

Cell Mol Gastroenterol Hepatol. 2015 Nov 1;1(6):646-663.e4.

8.

Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis.

Eguchi A, Yoshitomi T, Lazic M, Johnson CD, Vong LB, Wree A, Povero D, Papouchado BG, Nagasaki Y, Feldstein AE.

Nanomedicine (Lond). 2015;10(17):2697-708. doi: 10.2217/nnm.15.87. Epub 2015 May 28.

9.

Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation.

Wree A, Johnson CD, Font-Burgada J, Eguchi A, Povero D, Karin M, Feldstein AE.

Cell Death Differ. 2015 Dec;22(12):1985-94. doi: 10.1038/cdd.2015.46. Epub 2015 Apr 24.

10.

Microparticles release by adipocytes act as "find-me" signals to promote macrophage migration.

Eguchi A, Mulya A, Lazic M, Radhakrishnan D, Berk MP, Povero D, Gornicka A, Feldstein AE.

PLoS One. 2015 Apr 7;10(4):e0123110. doi: 10.1371/journal.pone.0123110. eCollection 2015.

11.

Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease.

Povero D, Eguchi A, Li H, Johnson CD, Papouchado BG, Wree A, Messer K, Feldstein AE.

PLoS One. 2014 Dec 3;9(12):e113651. doi: 10.1371/journal.pone.0113651. eCollection 2014.

12.

Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.

Lazic M, Inzaugarat ME, Povero D, Zhao IC, Chen M, Nalbandian M, Miller YI, Cherñavsky AC, Feldstein AE, Sears DD.

PLoS One. 2014 Sep 24;9(9):e107658. doi: 10.1371/journal.pone.0107658. eCollection 2014.

13.

Arginase 2 deficiency results in spontaneous steatohepatitis: a novel link between innate immune activation and hepatic de novo lipogenesis.

Navarro LA, Wree A, Povero D, Berk MP, Eguchi A, Ghosh S, Papouchado BG, Erzurum SC, Feldstein AE.

J Hepatol. 2015 Feb;62(2):412-20. doi: 10.1016/j.jhep.2014.09.015. Epub 2014 Sep 16.

14.

Caspase 3 inactivation protects against hepatic cell death and ameliorates fibrogenesis in a diet-induced NASH model.

Thapaliya S, Wree A, Povero D, Inzaugarat ME, Berk M, Dixon L, Papouchado BG, Feldstein AE.

Dig Dis Sci. 2014 Jun;59(6):1197-206. doi: 10.1007/s10620-014-3167-6. Epub 2014 May 3.

15.

Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice.

Lazic M, Eguchi A, Berk MP, Povero D, Papouchado B, Mulya A, Johnson CD, Feldstein AE.

J Hepatol. 2014 Jul;61(1):107-15. doi: 10.1016/j.jhep.2014.03.028. Epub 2014 Mar 27.

16.

Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells.

Povero D, Eguchi A, Niesman IR, Andronikou N, de Mollerat du Jeu X, Mulya A, Berk M, Lazic M, Thapaliya S, Parola M, Patel HH, Feldstein AE.

Sci Signal. 2013 Oct 8;6(296):ra88. doi: 10.1126/scisignal.2004512.

17.

Novel therapeutic targets for nonalcoholic fatty liver disease.

Eguchi A, Povero D, Alkhouri N, Feldstein AE.

Expert Opin Ther Targets. 2013 Jul;17(7):773-9. doi: 10.1517/14728222.2013.789502. Epub 2013 Apr 22. Review.

PMID:
23600493
18.

The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells.

Novo E, Povero D, Busletta C, Paternostro C, di Bonzo LV, Cannito S, Compagnone A, Bandino A, Marra F, Colombatto S, David E, Pinzani M, Parola M.

J Pathol. 2012 Mar;226(4):588-97. doi: 10.1002/path.3005. Epub 2011 Dec 5.

19.

Dissection of the biphasic nature of hypoxia-induced motogenic action in bone marrow-derived human mesenchymal stem cells.

Busletta C, Novo E, Valfrè Di Bonzo L, Povero D, Paternostro C, Ievolella M, Mareschi K, Ferrero I, Cannito S, Compagnone A, Bandino A, Colombatto S, Fagioli F, Parola M.

Stem Cells. 2011 Jun;29(6):952-63. doi: 10.1002/stem.642.

20.

Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells.

Novo E, Busletta C, Bonzo LV, Povero D, Paternostro C, Mareschi K, Ferrero I, David E, Bertolani C, Caligiuri A, Cannito S, Tamagno E, Compagnone A, Colombatto S, Marra F, Fagioli F, Pinzani M, Parola M.

J Hepatol. 2011 May;54(5):964-74. doi: 10.1016/j.jhep.2010.09.022. Epub 2010 Oct 31.

21.

Oxidative stress parameters in paediatric non-alcoholic fatty liver disease.

Nobili V, Parola M, Alisi A, Marra F, Piemonte F, Mombello C, Sutti S, Povero D, Maina V, Novo E, Albano E.

Int J Mol Med. 2010 Oct;26(4):471-6.

PMID:
20818484
22.

Liver fibrosis: a dynamic and potentially reversible process.

Povero D, Busletta C, Novo E, di Bonzo LV, Cannito S, Paternostro C, Parola M.

Histol Histopathol. 2010 Aug;25(8):1075-91. doi: 10.14670/HH-25.1075. Review.

23.

Angiogenesis and liver fibrogenesis.

Valfrè di Bonzo L, Novo E, Cannito S, Busletta C, Paternostro C, Povero D, Parola M.

Histol Histopathol. 2009 Oct;24(10):1323-41. doi: 10.14670/HH-24.1323. Review.

24.

Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells.

Cannito S, Novo E, Compagnone A, Valfrè di Bonzo L, Busletta C, Zamara E, Paternostro C, Povero D, Bandino A, Bozzo F, Cravanzola C, Bravoco V, Colombatto S, Parola M.

Carcinogenesis. 2008 Dec;29(12):2267-78. doi: 10.1093/carcin/bgn216. Epub 2008 Sep 12.

PMID:
18791199

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