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Items: 48


Mapping mononuclear phagocytes in blood, lungs, and lymph nodes of sarcoidosis patients.

Lepzien R, Rankin G, Pourazar J, Muala A, Eklund A, Grunewald J, Blomberg A, Smed-Sörensen A.

J Leukoc Biol. 2019 Apr;105(4):797-807. doi: 10.1002/JLB.5A0718-280RR. Epub 2019 Feb 11.


Cytotoxic lymphocytes in COPD airways: increased NK cells associated with disease, iNKT and NKT-like cells with current smoking.

Eriksson Ström J, Pourazar J, Linder R, Blomberg A, Lindberg A, Bucht A, Behndig AF.

Respir Res. 2018 Dec 7;19(1):244. doi: 10.1186/s12931-018-0940-7.


Proteolytic biomarkers are related to prognosis in COPD- report from a population-based cohort.

Linder R, Rönmark E, Pourazar J, Behndig AF, Blomberg A, Lindberg A.

Respir Res. 2018 Apr 12;19(1):64. doi: 10.1186/s12931-018-0772-5.


Mass spectrometry profiling reveals altered plasma levels of monohydroxy fatty acids and related lipids in healthy humans after controlled exposure to biodiesel exhaust.

Gouveia-Figueira S, Karimpour M, Bosson JA, Blomberg A, Unosson J, Sehlstedt M, Pourazar J, Sandström T, Behndig AF, Nording ML.

Anal Chim Acta. 2018 Aug 14;1018:62-69. doi: 10.1016/j.aca.2018.02.032. Epub 2018 Feb 20.


Urban particulate matter stimulation of human dendritic cells enhances priming of naive CD8 T lymphocytes.

Pfeffer PE, Ho TR, Mann EH, Kelly FJ, Sehlstedt M, Pourazar J, Dove RE, Sandstrom T, Mudway IS, Hawrylowicz CM.

Immunology. 2018 Apr;153(4):502-512. doi: 10.1111/imm.12852. Epub 2017 Nov 28.


Human hantavirus infection elicits pronounced redistribution of mononuclear phagocytes in peripheral blood and airways.

Scholz S, Baharom F, Rankin G, Maleki KT, Gupta S, Vangeti S, Pourazar J, Discacciati A, Höijer J, Bottai M, Björkström NK, Rasmuson J, Evander M, Blomberg A, Ljunggren HG, Klingström J, Ahlm C, Smed-Sörensen A.

PLoS Pathog. 2017 Jun 22;13(6):e1006462. doi: 10.1371/journal.ppat.1006462. eCollection 2017 Jun.


Mass spectrometry profiling of oxylipins, endocannabinoids, and N-acylethanolamines in human lung lavage fluids reveals responsiveness of prostaglandin E2 and associated lipid metabolites to biodiesel exhaust exposure.

Gouveia-Figueira S, Karimpour M, Bosson JA, Blomberg A, Unosson J, Pourazar J, Sandström T, Behndig AF, Nording ML.

Anal Bioanal Chem. 2017 Apr;409(11):2967-2980. doi: 10.1007/s00216-017-0243-8. Epub 2017 Feb 24.


Human Lung Dendritic Cells: Spatial Distribution and Phenotypic Identification in Endobronchial Biopsies Using Immunohistochemistry and Flow Cytometry.

Baharom F, Rankin G, Scholz S, Pourazar J, Ahlm C, Blomberg A, Smed-Sörensen A.

J Vis Exp. 2017 Jan 20;(119). doi: 10.3791/55222.


Dendritic Cells and Monocytes with Distinct Inflammatory Responses Reside in Lung Mucosa of Healthy Humans.

Baharom F, Thomas S, Rankin G, Lepzien R, Pourazar J, Behndig AF, Ahlm C, Blomberg A, Smed-Sörensen A.

J Immunol. 2016 Jun 1;196(11):4498-509. doi: 10.4049/jimmunol.1600071. Epub 2016 May 2.


Multi-platform metabolomics assays for human lung lavage fluids in an air pollution exposure study.

Surowiec I, Karimpour M, Gouveia-Figueira S, Wu J, Unosson J, Bosson JA, Blomberg A, Pourazar J, Sandström T, Behndig AF, Trygg J, Nording ML.

Anal Bioanal Chem. 2016 Jul;408(17):4751-64. doi: 10.1007/s00216-016-9566-0. Epub 2016 Apr 25.


Cytotoxic immune responses in the lungs correlate to disease severity in patients with hantavirus infection.

Rasmuson J, Pourazar J, Mohamed N, Lejon K, Evander M, Blomberg A, Ahlm C.

Eur J Clin Microbiol Infect Dis. 2016 Apr;35(4):713-21. doi: 10.1007/s10096-016-2592-1. Epub 2016 Feb 12.


Cigarette smoke-induced induction of antioxidant enzyme activities in airway leukocytes is absent in active smokers with COPD.

Dove RE, Leong-Smith P, Roos-Engstrand E, Pourazar J, Shah M, Behndig AF, Mudway IS, Blomberg A.

Eur Clin Respir J. 2015 Jul 16;2. doi: 10.3402/ecrj.v2.27837. eCollection 2015.


Acute exposure to wood smoke from incomplete combustion--indications of cytotoxicity.

Muala A, Rankin G, Sehlstedt M, Unosson J, Bosson JA, Behndig A, Pourazar J, Nyström R, Pettersson E, Bergvall C, Westerholm R, Jalava PI, Happo MS, Uski O, Hirvonen MR, Kelly FJ, Mudway IS, Blomberg A, Boman C, Sandström T.

Part Fibre Toxicol. 2015 Oct 29;12:33. doi: 10.1186/s12989-015-0111-7.


Identification of vitamin C transporters in the human airways: a cross-sectional in vivo study.

Larsson N, Rankin GD, Bicer EM, Roos-Engstrand E, Pourazar J, Blomberg A, Mudway IS, Behndig AF.

BMJ Open. 2015 Apr 8;5(4):e006979. doi: 10.1136/bmjopen-2014-006979.


Serum metalloproteinase-9 is related to COPD severity and symptoms - cross-sectional data from a population based cohort-study.

Linder R, Rönmark E, Pourazar J, Behndig A, Blomberg A, Lindberg A.

Respir Res. 2015 Feb 21;16:28. doi: 10.1186/s12931-015-0188-4.


Effect of wood smoke exposure on vascular function and thrombus formation in healthy fire fighters.

Hunter AL, Unosson J, Bosson JA, Langrish JP, Pourazar J, Raftis JB, Miller MR, Lucking AJ, Boman C, Nyström R, Donaldson K, Flapan AD, Shah AS, Pung L, Sadiktsis I, Masala S, Westerholm R, Sandström T, Blomberg A, Newby DE, Mills NL.

Part Fibre Toxicol. 2014 Dec 9;11:62. doi: 10.1186/s12989-014-0062-4.


Assessment of the capacity of vehicle cabin air inlet filters to reduce diesel exhaust-induced symptoms in human volunteers.

Muala A, Sehlstedt M, Bion A, Osterlund C, Bosson JA, Behndig AF, Pourazar J, Bucht A, Boman C, Mudway IS, Langrish JP, Couderc S, Blomberg A, Sandström T.

Environ Health. 2014 Mar 13;13(1):16. doi: 10.1186/1476-069X-13-16.


Lipid mediator profiles differ between lung compartments in asthmatic and healthy humans.

Larsson N, Lundström SL, Pinto R, Rankin G, Karimpour M, Blomberg A, Sandström T, Pourazar J, Trygg J, Behndig AF, Wheelock CE, Nording ML.

Eur Respir J. 2014 Feb;43(2):453-63. doi: 10.1183/09031936.00209412. Epub 2013 Sep 13.


Altered nitric oxide bioavailability contributes to diesel exhaust inhalation-induced cardiovascular dysfunction in man.

Langrish JP, Unosson J, Bosson J, Barath S, Muala A, Blackwell S, Söderberg S, Pourazar J, Megson IL, Treweeke A, Sandström T, Newby DE, Blomberg A, Mills NL.

J Am Heart Assoc. 2013 Feb 19;2(1):e004309. doi: 10.1161/JAHA.112.004309.


Airway inflammatory responses to diesel exhaust in allergic rhinitics.

Larsson N, Brown J, Stenfors N, Wilson S, Mudway IS, Pourazar J, Behndig AF.

Inhal Toxicol. 2013 Feb;25(3):160-7. doi: 10.3109/08958378.2013.765932.


Expansion of CD4+CD25+ helper T cells without regulatory function in smoking and COPD.

Roos-Engstrand E, Pourazar J, Behndig AF, Bucht A, Blomberg A.

Respir Res. 2011 Jun 8;12:74. doi: 10.1186/1465-9921-12-74.


Particle traps prevent adverse vascular and prothrombotic effects of diesel engine exhaust inhalation in men.

Lucking AJ, Lundbäck M, Barath SL, Mills NL, Sidhu MK, Langrish JP, Boon NA, Pourazar J, Badimon JJ, Gerlofs-Nijland ME, Cassee FR, Boman C, Donaldson K, Sandstrom T, Newby DE, Blomberg A.

Circulation. 2011 Apr 26;123(16):1721-8. doi: 10.1161/CIRCULATIONAHA.110.987263. Epub 2011 Apr 11.


Presence of activated airway T lymphocytes in human puumala hantavirus disease.

Rasmuson J, Pourazar J, Linderholm M, Sandström T, Blomberg A, Ahlm C.

Chest. 2011 Sep;140(3):715-722. doi: 10.1378/chest.10-2791. Epub 2011 Mar 24.


Airway inflammatory response to diesel exhaust generated at urban cycle running conditions.

Sehlstedt M, Behndig AF, Boman C, Blomberg A, Sandström T, Pourazar J.

Inhal Toxicol. 2010 Dec;22(14):1144-50. doi: 10.3109/08958378.2010.529181. Epub 2010 Nov 29.


Cytotoxic T cells expressing the co-stimulatory receptor NKG2 D are increased in cigarette smoking and COPD.

Roos-Engstrand E, Pourazar J, Behndig AF, Blomberg A, Bucht A.

Respir Res. 2010 Sep 24;11:128. doi: 10.1186/1465-9921-11-128.


Antioxidant airway responses following experimental exposure to wood smoke in man.

Sehlstedt M, Dove R, Boman C, Pagels J, Swietlicki E, Löndahl J, Westerholm R, Bosson J, Barath S, Behndig AF, Pourazar J, Sandström T, Mudway IS, Blomberg A.

Part Fibre Toxicol. 2010 Aug 20;7:21. doi: 10.1186/1743-8977-7-21.


Ozone exposure enhances mast-cell inflammation in asthmatic airways despite inhaled corticosteroid therapy.

Stenfors N, Bosson J, Helleday R, Behndig AF, Pourazar J, Törnqvist H, Kelly FJ, Frew AJ, Sandström T, Mudway IS, Blomberg A.

Inhal Toxicol. 2010 Feb;22(2):133-9. doi: 10.3109/08958370903005736.


Early suppression of NFkappaB and IL-8 in bronchial epithelium after ozone exposure in healthy human subjects.

Bosson J, Blomberg A, Pourazar J, Mudway IS, Frew AJ, Kelly FJ, Sandström T.

Inhal Toxicol. 2009 Sep;21(11):913-9. doi: 10.1080/08958370802657389.


Influence of smoking cessation on airway T lymphocyte subsets in COPD.

Roos-Engstrand E, Ekstrand-Hammarström B, Pourazar J, Behndig AF, Bucht A, Blomberg A.

COPD. 2009 Apr;6(2):112-20. doi: 10.1080/15412550902755358.


Diesel exhaust inhalation increases thrombus formation in man.

Lucking AJ, Lundback M, Mills NL, Faratian D, Barath SL, Pourazar J, Cassee FR, Donaldson K, Boon NA, Badimon JJ, Sandstrom T, Blomberg A, Newby DE.

Eur Heart J. 2008 Dec;29(24):3043-51. doi: 10.1093/eurheartj/ehn464. Epub 2008 Oct 24.


Increased intraepithelial T-cells in stable COPD.

Löfdahl MJ, Roos-Engstrand E, Pourazar J, Bucht A, Dahlen B, Elmberger G, Blomberg A, Sköld CM.

Respir Med. 2008 Dec;102(12):1812-8. doi: 10.1016/j.rmed.2008.06.013. Epub 2008 Aug 15.


Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium.

Pourazar J, Blomberg A, Kelly FJ, Davies DE, Wilson SJ, Holgate ST, Sandström T.

Part Fibre Toxicol. 2008 May 6;5:8. doi: 10.1186/1743-8977-5-8.


Diesel exhaust exposure enhances the ozone-induced airway inflammation in healthy humans.

Bosson J, Barath S, Pourazar J, Behndig AF, Sandström T, Blomberg A, Adelroth E.

Eur Respir J. 2008 Jun;31(6):1234-40. doi: 10.1183/09031936.00078407. Epub 2008 Mar 5.


Epithelial expression of mRNA and protein for IL-6, IL-10 and TNF-alpha in endobronchial biopsies in horses with recurrent airway obstruction.

Riihimäki M, Raine A, Pourazar J, Sandström T, Art T, Lekeux P, Couëtil L, Pringle J.

BMC Vet Res. 2008 Feb 23;4:8. doi: 10.1186/1746-6148-4-8.


Bronchoalveolar matrix metalloproteinase 9 relates to restrictive lung function impairment in systemic sclerosis.

Andersen GN, Nilsson K, Pourazar J, Hackett TL, Kazzam E, Blomberg A, Waldenström A, Warner J, Rantapää-Dahlqvist S, Mincheva-Nilsson L, Sandström T.

Respir Med. 2007 Oct;101(10):2199-206. Epub 2007 Jul 20.


Lower airways inflammation in allergic rhinitics: a comparison with asthmatics and normal controls.

Brown JL, Behndig AF, Sekerel BE, Pourazar J, Blomberg A, Kelly FJ, Sandström T, Frew AJ, Wilson SJ.

Clin Exp Allergy. 2007 May;37(5):688-95.


Ozone enhances the airway inflammation initiated by diesel exhaust.

Bosson J, Pourazar J, Forsberg B, Adelroth E, Sandström T, Blomberg A.

Respir Med. 2007 Jun;101(6):1140-6. Epub 2006 Dec 29.


Vitamin supplementation does not protect against symptoms in ozone-responsive subjects.

Mudway IS, Behndig AF, Helleday R, Pourazar J, Frew AJ, Kelly FJ, Blomberg A.

Free Radic Biol Med. 2006 May 15;40(10):1702-12.


Airway inflammation in iron ore miners exposed to dust and diesel exhaust.

Adelroth E, Hedlund U, Blomberg A, Helleday R, Ledin MC, Levin JO, Pourazar J, Sandström T, Järvholm B.

Eur Respir J. 2006 Apr;27(4):714-9. Epub 2006 Feb 2.


Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure.

Roos-Engstrand E, Wallin A, Bucht A, Pourazar J, Sandström T, Blomberg A.

Eur Respir J. 2005 May;25(5):797-803.


Diesel exhaust activates redox-sensitive transcription factors and kinases in human airways.

Pourazar J, Mudway IS, Samet JM, Helleday R, Blomberg A, Wilson SJ, Frew AJ, Kelly FJ, Sandström T.

Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L724-30. Epub 2005 Mar 4.


LPS-induced bronchoalveolar neutrophilia; effects of salmeterol treatment.

Wallin A, Pourazar J, Sandström T.

Respir Med. 2004 Nov;98(11):1087-92.


Diesel exhaust exposure enhances the expression of IL-13 in the bronchial epithelium of healthy subjects.

Pourazar J, Frew AJ, Blomberg A, Helleday R, Kelly FJ, Wilson S, Sandström T.

Respir Med. 2004 Sep;98(9):821-5.


Ozone-induced bronchial epithelial cytokine expression differs between healthy and asthmatic subjects.

Bosson J, Stenfors N, Bucht A, Helleday R, Pourazar J, Holgate ST, Kelly FJ, Sandström T, Wilson S, Frew AJ, Blomberg A.

Clin Exp Allergy. 2003 Jun;33(6):777-82.


Effect of ozone on bronchial mucosal inflammation in asthmatic and healthy subjects.

Stenfors N, Pourazar J, Blomberg A, Krishna MT, Mudway I, Helleday R, Kelly FJ, Frew AJ, Sandström T.

Respir Med. 2002 May;96(5):352-8.


Diesel exhaust enhances airway responsiveness in asthmatic subjects.

Nordenhäll C, Pourazar J, Ledin MC, Levin JO, Sandström T, Adelroth E.

Eur Respir J. 2001 May;17(5):909-15.


Airway inflammation following exposure to diesel exhaust: a study of time kinetics using induced sputum.

Nordenhäll C, Pourazar J, Blomberg A, Levin JO, Sandström T, Adelroth E.

Eur Respir J. 2000 Jun;15(6):1046-51.


Acute exposure to diesel exhaust increases IL-8 and GRO-alpha production in healthy human airways.

Salvi SS, Nordenhall C, Blomberg A, Rudell B, Pourazar J, Kelly FJ, Wilson S, Sandström T, Holgate ST, Frew AJ.

Am J Respir Crit Care Med. 2000 Feb;161(2 Pt 1):550-7.


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