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Items: 26


Quantifying Microsatellite Mutation Rates from Intestinal Stem Cell Dynamics in Msh2-Deficient Murine Epithelium.

Christopher J, Thorsen AS, Abujudeh S, Lourenço FC, Kemp R, Potter PK, Morrissey E, Hazelwood L, Winton DJ.

Genetics. 2019 Jul;212(3):655-665. doi: 10.1534/genetics.119.302268. Epub 2019 May 24.


Mouse Idh3a mutations cause retinal degeneration and reduced mitochondrial function.

Findlay AS, Carter RN, Starbuck B, McKie L, Nováková K, Budd PS, Keighren MA, Marsh JA, Cross SH, Simon MM, Potter PK, Morton NM, Jackson IJ.

Dis Model Mech. 2018 Dec 18;11(12). pii: dmm036426. doi: 10.1242/dmm.036426.


An N-Ethyl-N-Nitrosourea (ENU) Mutagenized Mouse Model for Autosomal Dominant Nonsyndromic Kyphoscoliosis Due to Vertebral Fusion.

Esapa CT, Piret SE, Nesbit MA, Thomas GP, Coulton LA, Gallagher OM, Simon MM, Kumar S, Mallon AM, Bellantuono I, Brown MA, Croucher PI, Potter PK, Brown SD, Cox RD, Thakker RV.

JBMR Plus. 2018 Mar 8;2(3):154-163. doi: 10.1002/jbm4.10033. eCollection 2018 May.


Studying Osteoarthritis Pathogenesis in Mice.

Blease A, Das Neves Borges P, Curtinha M, Javaheri B, von Loga IS, Parisi I, Zarebska J, Pitsillides A, Vincent TL, Potter PK.

Curr Protoc Mouse Biol. 2018 Dec;8(4):e50. doi: 10.1002/cpmo.50. Epub 2018 Sep 21.


Generation and Identification of Mutations Resulting in Chronic and Age-Related Phenotypes in Mice.

Blease A, Nicol T, Falcone S, Starbuck B, Greenaway S, Hutchinson M, Potter PK.

Curr Protoc Mouse Biol. 2018 Jun;8(2):e42. doi: 10.1002/cpmo.42. Epub 2018 May 21.


Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

Potter PK, Bowl MR, Jeyarajan P, Wisby L, Blease A, Goldsworthy ME, Simon MM, Greenaway S, Michel V, Barnard A, Aguilar C, Agnew T, Banks G, Blake A, Chessum L, Dorning J, Falcone S, Goosey L, Harris S, Haynes A, Heise I, Hillier R, Hough T, Hoslin A, Hutchison M, King R, Kumar S, Lad HV, Law G, MacLaren RE, Morse S, Nicol T, Parker A, Pickford K, Sethi S, Starbuck B, Stelma F, Cheeseman M, Cross SH, Foster RG, Jackson IJ, Peirson SN, Thakker RV, Vincent T, Scudamore C, Wells S, El-Amraoui A, Petit C, Acevedo-Arozena A, Nolan PM, Cox R, Mallon AM, Brown SD.

Nat Commun. 2016 Aug 18;7:12444. doi: 10.1038/ncomms12444.


With mouse age comes wisdom: A review and suggestions of relevant mouse models for age-related conditions.

Drechsler S, Lynch MA, Novella S, González-Navarro H, Hecimovic S, Barini E, Tucci V, Castro RE, Vandenbroucke RE, Osuchowski M, Potter PK.

Mech Ageing Dev. 2016 Dec;160:54-68. doi: 10.1016/j.mad.2016.07.005. Epub 2016 Jul 21. Review.


Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing.

Nicod J, Davies RW, Cai N, Hassett C, Goodstadt L, Cosgrove C, Yee BK, Lionikaite V, McIntyre RE, Remme CA, Lodder EM, Gregory JS, Hough T, Joynson R, Phelps H, Nell B, Rowe C, Wood J, Walling A, Bopp N, Bhomra A, Hernandez-Pliego P, Callebert J, Aspden RM, Talbot NP, Robbins PA, Harrison M, Fray M, Launay JM, Pinto YM, Blizard DA, Bezzina CR, Adams DJ, Franken P, Weaver T, Wells S, Brown SD, Potter PK, Klenerman P, Lionikas A, Mott R, Flint J.

Nat Genet. 2016 Aug;48(8):912-8. doi: 10.1038/ng.3595. Epub 2016 Jul 4.


The Mammalian Genome special issue on ageing.

Potter PK.

Mamm Genome. 2016 Aug;27(7-8):257-8. doi: 10.1007/s00335-016-9652-9. No abstract available.


Current strategies for mutation detection in phenotype-driven screens utilising next generation sequencing.

Simon MM, Moresco EM, Bull KR, Kumar S, Mallon AM, Beutler B, Potter PK.

Mamm Genome. 2015 Oct;26(9-10):486-500. doi: 10.1007/s00335-015-9603-x. Epub 2015 Oct 8. Review.


The Interrelationship between Disease and Ageing and the Implications for Longevity.

Potter PK.

Curr Aging Sci. 2015 Apr 22. [Epub ahead of print]


Modelling age-related metabolic disorders in the mouse.

Goldsworthy ME, Potter PK.

Mamm Genome. 2014 Oct;25(9-10):487-96. doi: 10.1007/s00335-014-9539-6. Epub 2014 Aug 15. Review.


A CNS-specific hypomorphic Pdgfr-beta mutant model of diabetic retinopathy.

Jadeja S, Mort RL, Keighren M, Hart AW, Joynson R, Wells S, Potter PK, Jackson IJ.

Invest Ophthalmol Vis Sci. 2013 May 1;54(5):3569-78. doi: 10.1167/iovs.12-11125.


Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations.

Bull KR, Rimmer AJ, Siggs OM, Miosge LA, Roots CM, Enders A, Bertram EM, Crockford TL, Whittle B, Potter PK, Simon MM, Mallon AM, Brown SD, Beutler B, Goodnow CC, Lunter G, Cornall RJ.

PLoS Genet. 2013;9(1):e1003219. doi: 10.1371/journal.pgen.1003219. Epub 2013 Jan 31.


ENU-based phenotype-driven screening.

Ripoll VM, Kong PL, Potter PK.

Methods Mol Biol. 2012;844:1-13. doi: 10.1007/978-1-61779-527-5_1.


HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.

Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD.

PLoS Genet. 2011 Oct;7(10):e1002336. doi: 10.1371/journal.pgen.1002336. Epub 2011 Oct 20.


A defect in Marco expression contributes to systemic lupus erythematosus development via failure to clear apoptotic cells.

Rogers NJ, Lees MJ, Gabriel L, Maniati E, Rose SJ, Potter PK, Morley BJ.

J Immunol. 2009 Feb 15;182(4):1982-90. doi: 10.4049/jimmunol.0801320.


Increased positive selection of B1 cells and reduced B cell tolerance to intracellular antigens in c1q-deficient mice.

Ferry H, Potter PK, Crockford TL, Nijnik A, Ehrenstein MR, Walport MJ, Botto M, Cornall RJ.

J Immunol. 2007 Mar 1;178(5):2916-22.


Efficient clearance of opsonised apoptotic cells in the absence of PECAM-1.

Potter PK, Larbi KY, Nourshargh S, Botto M.

Mol Immunol. 2007 Feb;44(6):1135-40. Epub 2006 Sep 5.


Lupus-prone mice have an abnormal response to thioglycolate and an impaired clearance of apoptotic cells.

Potter PK, Cortes-Hernandez J, Quartier P, Botto M, Walport MJ.

J Immunol. 2003 Mar 15;170(6):3223-32.


Murine glomerular mesangial cell uptake of apoptotic cells is inefficient and involves serum-mediated but complement-independent mechanisms.

Cortes-Hernandez J, Fossati-Jimack L, Carugati A, Potter PK, Walport MJ, Cook HT, Botto M.

Clin Exp Immunol. 2002 Dec;130(3):459-66.


Accurate intracellular localization of HLA-DM requires correct spacing of a cytoplasmic YTPL targeting motif relative to the transmembrane domain.

Potter PK, Copier J, Sacks SH, Calafat J, Janssen H, Neefjes JJ, Kelly AP.

Eur J Immunol. 1999 Dec;29(12):3936-44.


A symposium on the administrative residency.


Hosp Manage. 1950 Jul;70(1):38-9. No abstract available.


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