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Items: 1 to 50 of 148

1.

Genetic and Pharmacological Targeting of Heat Shock Protein 70 in the Mouse Amygdala-Kindling Model.

von Rüden EL, Wolf F, Gualtieri F, Keck M, Hunt CR, Pandita TK, Potschka H.

ACS Chem Neurosci. 2018 Nov 16. doi: 10.1021/acschemneuro.8b00475. [Epub ahead of print]

PMID:
30396268
2.

Imaging biomarkers of behavioral impairments: A pilot micro-positron emission tomographic study in a rat electrical post-status epilepticus model.

van Dijk RM, Di Liberto V, Brendel M, Waldron AM, Möller C, Gildehaus FJ, von Ungern-Sternberg B, Lindner M, Ziegler S, Hellweg R, Gass P, Bartenstein P, Potschka H.

Epilepsia. 2018 Dec;59(12):2194-2205. doi: 10.1111/epi.14586. Epub 2018 Oct 28.

PMID:
30370531
3.

Seizure occurrence in dogs under primary veterinary care in the UK: prevalence and risk factors.

Erlen A, Potschka H, Volk HA, Sauter-Louis C, O'Neill DG.

J Vet Intern Med. 2018 Sep;32(5):1665-1676. doi: 10.1111/jvim.15290. Epub 2018 Sep 14.

4.

Genetic Modulation of HSPA1A Accelerates Kindling Progression and Exerts Pro-convulsant Effects.

von Rüden EL, Wolf F, Keck M, Gualtieri F, Nowakowska M, Oglesbee M, Potschka H.

Neuroscience. 2018 Aug 21;386:108-120. doi: 10.1016/j.neuroscience.2018.06.031. Epub 2018 Jun 30.

PMID:
29964156
5.

Perampanel: Does it have broad-spectrum potential?

Potschka H, Trinka E.

Epilepsia. 2018 Jun 28. doi: 10.1111/epi.14456. [Epub ahead of print] Review.

PMID:
29953584
6.

Imaging correlates of behavioral impairments: An experimental PET study in the rat pilocarpine epilepsy model.

Di Liberto V, van Dijk RM, Brendel M, Waldron AM, Möller C, Koska I, Seiffert I, Gualtieri F, Gildehaus FJ, von Ungern-Sternberg B, Lindner M, Ziegler S, Palme R, Hellweg R, Gass P, Bartenstein P, Potschka H.

Neurobiol Dis. 2018 Oct;118:9-21. doi: 10.1016/j.nbd.2018.06.010. Epub 2018 Jun 20.

PMID:
29933054
7.

Toward evidence-based severity assessment in rat models with repeated seizures: I. Electrical kindling.

Möller C, Wolf F, van Dijk RM, Di Liberto V, Russmann V, Keck M, Palme R, Hellweg R, Gass P, Otzdorff C, Potschka H.

Epilepsia. 2018 Apr;59(4):765-777. doi: 10.1111/epi.14028. Epub 2018 Feb 26.

PMID:
29479675
8.

Proteomic profiling of epileptogenesis in a rat model: Focus on cell stress, extracellular matrix and angiogenesis.

Keck M, van Dijk RM, Deeg CA, Kistler K, Walker A, von Rüden EL, Russmann V, Hauck SM, Potschka H.

Neurobiol Dis. 2018 Apr;112:119-135. doi: 10.1016/j.nbd.2018.01.013. Epub 2018 Feb 3.

PMID:
29413716
9.

Identification and characterization of outcome measures reported in animal models of epilepsy: Protocol for a systematic review of the literature-A TASK2 report of the AES/ILAE Translational Task Force of the ILAE.

Simonato M, Iyengar S, Brooks-Kayal A, Collins S, Depaulis A, Howells DW, Jensen F, Liao J, Macleod MR, Patel M, Potschka H, Walker M, Whittemore V, Sena ES.

Epilepsia. 2017 Nov;58 Suppl 4:68-77. doi: 10.1111/epi.13908.

10.

Neuroinflammation imaging markers for epileptogenesis.

Koepp MJ, Årstad E, Bankstahl JP, Dedeurwaerdere S, Friedman A, Potschka H, Ravizza T, Theodore WH, Baram TZ.

Epilepsia. 2017 Jul;58 Suppl 3:11-19. doi: 10.1111/epi.13778.

11.

A systems level analysis of epileptogenesis-associated proteome alterations.

Keck M, Androsova G, Gualtieri F, Walker A, von Rüden EL, Russmann V, Deeg CA, Hauck SM, Krause R, Potschka H.

Neurobiol Dis. 2017 Sep;105:164-178. doi: 10.1016/j.nbd.2017.05.017. Epub 2017 May 30.

12.

Hepatotoxicity of Antimycotics Used for Invasive Fungal Infections: In Vitro Results.

Doß S, Potschka H, Doß F, Mitzner S, Sauer M.

Biomed Res Int. 2017;2017:9658018. doi: 10.1155/2017/9658018. Epub 2017 Apr 4.

13.

Identification of brain regions predicting epileptogenesis by serial [18F]GE-180 positron emission tomography imaging of neuroinflammation in a rat model of temporal lobe epilepsy.

Russmann V, Brendel M, Mille E, Helm-Vicidomini A, Beck R, Günther L, Lindner S, Rominger A, Keck M, Salvamoser JD, Albert NL, Bartenstein P, Potschka H.

Neuroimage Clin. 2017 Apr 5;15:35-44. doi: 10.1016/j.nicl.2017.04.003. eCollection 2017.

14.

Systematic account of animal poisonings in Germany, 2012-2015.

McFarland SE, Mischke RH, Hopster-Iversen C, von Krueger X, Ammer H, Potschka H, Stürer A, Begemann K, Desel H, Greiner M.

Vet Rec. 2017 Apr 1;180(13):327. doi: 10.1136/vr.103973. Epub 2017 Feb 24.

PMID:
28235786
15.

WONOEP appraisal: Imaging biomarkers in epilepsy.

van Vliet EA, Dedeurwaerdere S, Cole AJ, Friedman A, Koepp MJ, Potschka H, Immonen R, Pitkänen A, Federico P.

Epilepsia. 2017 Mar;58(3):315-330. doi: 10.1111/epi.13621. Epub 2016 Nov 24. Review.

16.

miRNA-187-3p-Mediated Regulation of the KCNK10/TREK-2 Potassium Channel in a Rat Epilepsy Model.

Haenisch S, von Rüden EL, Wahmkow H, Rettenbeck ML, Michler C, Russmann V, Bruckmueller H, Waetzig V, Cascorbi I, Potschka H.

ACS Chem Neurosci. 2016 Nov 16;7(11):1585-1594. Epub 2016 Sep 22.

PMID:
27609046
17.

Synergism of perampanel and zonisamide in the rat amygdala kindling model of temporal lobe epilepsy.

Russmann V, Salvamoser JD, Rettenbeck ML, Komori T, Potschka H.

Epilepsia. 2016 Apr;57(4):638-47. doi: 10.1111/epi.13328. Epub 2016 Feb 8.

18.

A retrospective evaluation of species-specific sensitivity for neurological signs in toxicological studies: Is the dog more sensitive than the non-human primate?

Backes K, Lorenz H, Laplanche L, Hudzik TJ, Potschka H, Hempel K.

Toxicol Lett. 2016 Jan 22;243:78-87. doi: 10.1016/j.toxlet.2015.12.007. Epub 2015 Dec 28.

PMID:
26732424
19.

Proteomic profiling of epileptogenesis in a rat model: Focus on inflammation.

Walker A, Russmann V, Deeg CA, von Toerne C, Kleinwort KJH, Szober C, Rettenbeck ML, von Rüden EL, Goc J, Ongerth T, Boes K, Salvamoser JD, Vezzani A, Hauck SM, Potschka H.

Brain Behav Immun. 2016 Mar;53:138-158. doi: 10.1016/j.bbi.2015.12.007. Epub 2015 Dec 11.

PMID:
26685804
20.

Minocycline fails to exert antiepileptogenic effects in a rat status epilepticus model.

Russmann V, Goc J, Boes K, Ongerth T, Salvamoser JD, Siegl C, Potschka H.

Eur J Pharmacol. 2016 Jan 15;771:29-39. doi: 10.1016/j.ejphar.2015.12.002. Epub 2015 Dec 8.

PMID:
26681545
21.

International veterinary epilepsy task force recommendations for systematic sampling and processing of brains from epileptic dogs and cats.

Matiasek K, Pumarola I Batlle M, Rosati M, Fernández-Flores F, Fischer A, Wagner E, Berendt M, Bhatti SF, De Risio L, Farquhar RG, Long S, Muñana K, Patterson EE, Pakozdy A, Penderis J, Platt S, Podell M, Potschka H, Rusbridge C, Stein VM, Tipold A, Volk HA.

BMC Vet Res. 2015 Aug 28;11:216. doi: 10.1186/s12917-015-0467-9.

22.

International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol.

Rusbridge C, Long S, Jovanovik J, Milne M, Berendt M, Bhatti SF, De Risio L, Farqhuar RG, Fischer A, Matiasek K, Muñana K, Patterson EE, Pakozdy A, Penderis J, Platt S, Podell M, Potschka H, Stein VM, Tipold A, Volk HA.

BMC Vet Res. 2015 Aug 28;11:194. doi: 10.1186/s12917-015-0466-x.

23.

International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe.

Bhatti SF, De Risio L, Muñana K, Penderis J, Stein VM, Tipold A, Berendt M, Farquhar RG, Fischer A, Long S, Löscher W, Mandigers PJ, Matiasek K, Pakozdy A, Patterson EE, Platt S, Podell M, Potschka H, Rusbridge C, Volk HA.

BMC Vet Res. 2015 Aug 28;11:176. doi: 10.1186/s12917-015-0464-z.

24.

International veterinary epilepsy task force consensus proposal: diagnostic approach to epilepsy in dogs.

De Risio L, Bhatti S, Muñana K, Penderis J, Stein V, Tipold A, Berendt M, Farqhuar R, Fischer A, Long S, Mandigers PJ, Matiasek K, Packer RM, Pakozdy A, Patterson N, Platt S, Podell M, Potschka H, Batlle MP, Rusbridge C, Volk HA.

BMC Vet Res. 2015 Aug 28;11:148. doi: 10.1186/s12917-015-0462-1.

25.

International veterinary epilepsy task force consensus report on epilepsy definition, classification and terminology in companion animals.

Berendt M, Farquhar RG, Mandigers PJ, Pakozdy A, Bhatti SF, De Risio L, Fischer A, Long S, Matiasek K, Muñana K, Patterson EE, Penderis J, Platt S, Podell M, Potschka H, Pumarola MB, Rusbridge C, Stein VM, Tipold A, Volk HA.

BMC Vet Res. 2015 Aug 28;11:182. doi: 10.1186/s12917-015-0461-2.

26.

International veterinary epilepsy task force consensus proposal: outcome of therapeutic interventions in canine and feline epilepsy.

Potschka H, Fischer A, Löscher W, Patterson N, Bhatti S, Berendt M, De Risio L, Farquhar R, Long S, Mandigers P, Matiasek K, Muñana K, Pakozdy A, Penderis J, Platt S, Podell M, Rusbridge C, Stein V, Tipold A, Volk HA.

BMC Vet Res. 2015 Aug 28;11:177. doi: 10.1186/s12917-015-0465-y.

27.

Expression regulation and targeting of the peroxisome proliferator-activated receptor γ following electrically-induced status epilepticus.

Boes K, Russmann V, Ongerth T, Licko T, Salvamoser JD, Siegl C, Potschka H.

Neurosci Lett. 2015 Sep 14;604:151-6. doi: 10.1016/j.neulet.2015.08.007. Epub 2015 Aug 7.

PMID:
26259695
28.

Microglial ROS production in an electrical rat post-status epilepticus model of epileptogenesis.

Rettenbeck ML, von Rüden EL, Bienas S, Carlson R, Stein VM, Tipold A, Potschka H.

Neurosci Lett. 2015 Jul 10;599:146-51. doi: 10.1016/j.neulet.2015.05.041. Epub 2015 May 22.

PMID:
26007700
29.

Glutamate-Mediated Down-Regulation of the Multidrug-Resistance Protein BCRP/ABCG2 in Porcine and Human Brain Capillaries.

Salvamoser JD, Avemary J, Luna-Munguia H, Pascher B, Getzinger T, Pieper T, Kudernatsch M, Kluger G, Potschka H.

Mol Pharm. 2015 Jun 1;12(6):2049-60. doi: 10.1021/mp500841w. Epub 2015 Apr 30.

PMID:
25898179
30.

N-acetyl-L-leucine accelerates vestibular compensation after unilateral labyrinthectomy by action in the cerebellum and thalamus.

Günther L, Beck R, Xiong G, Potschka H, Jahn K, Bartenstein P, Brandt T, Dutia M, Dieterich M, Strupp M, la Fougère C, Zwergal A.

PLoS One. 2015 Mar 24;10(3):e0120891. doi: 10.1371/journal.pone.0120891. eCollection 2015.

31.

Inhibition of monoacylglycerol lipase mediates a cannabinoid 1-receptor dependent delay of kindling progression in mice.

von Rüden EL, Bogdanovic RM, Wotjak CT, Potschka H.

Neurobiol Dis. 2015 May;77:238-45. doi: 10.1016/j.nbd.2015.03.016. Epub 2015 Mar 18.

PMID:
25796567
32.

Glutamate-mediated upregulation of the multidrug resistance protein 2 in porcine and human brain capillaries.

Luna-Munguia H, Salvamoser JD, Pascher B, Pieper T, Getzinger T, Kudernatsch M, Kluger G, Potschka H.

J Pharmacol Exp Ther. 2015 Feb;352(2):368-78. doi: 10.1124/jpet.114.218180. Epub 2014 Dec 12.

33.

The mixed blessing of treating symptoms in acute vestibular failure--evidence from a 4-aminopyridine experiment.

Beck R, Günther L, Xiong G, Potschka H, Böning G, Bartenstein P, Brandt T, Jahn K, Dieterich M, Strupp M, la Fougère C, Zwergal A.

Exp Neurol. 2014 Nov;261:638-45. doi: 10.1016/j.expneurol.2014.08.013. Epub 2014 Aug 23.

PMID:
25157903
34.

Analysis in conditional cannabinoid 1 receptor-knockout mice reveals neuronal subpopulation-specific effects on epileptogenesis in the kindling paradigm.

von Rüden EL, Jafari M, Bogdanovic RM, Wotjak CT, Potschka H.

Neurobiol Dis. 2015 Jan;73:334-47. doi: 10.1016/j.nbd.2014.08.001. Epub 2014 Aug 11.

PMID:
25123336
35.

Targeting of microglial KCa3.1 channels by TRAM-34 exacerbates hippocampal neurodegeneration and does not affect ictogenesis and epileptogenesis in chronic temporal lobe epilepsy models.

Ongerth T, Russmann V, Fischborn S, Boes K, Siegl C, Potschka H.

Eur J Pharmacol. 2014 Oct 5;740:72-80. doi: 10.1016/j.ejphar.2014.06.061. Epub 2014 Jul 10.

PMID:
25016931
36.

(R)-[11C]PK11195 brain uptake as a biomarker of inflammation and antiepileptic drug resistance: evaluation in a rat epilepsy model.

Bogdanović RM, Syvänen S, Michler C, Russmann V, Eriksson J, Windhorst AD, Lammertsma AA, de Lange EC, Voskuyl RA, Potschka H.

Neuropharmacology. 2014 Oct;85:104-12. doi: 10.1016/j.neuropharm.2014.05.002. Epub 2014 May 28.

PMID:
24880085
37.

Pre-treatment with the NMDA receptor glycine-binding site antagonist L-701,324 improves pharmacosensitivity in a mouse kindling model.

Zellinger C, Salvamoser JD, Soerensen J, van Vliet EA, Aronica E, Gorter J, Potschka H.

Epilepsy Res. 2014 May;108(4):634-43. doi: 10.1016/j.eplepsyres.2014.02.012. Epub 2014 Mar 2.

PMID:
24656981
38.

Impact of the neural cell adhesion molecule-derived peptide FGL on seizure progression and cellular alterations in the mouse kindling model.

Zellinger C, Salvamoser JD, Seeger N, Russmann V, Potschka H.

ACS Chem Neurosci. 2014 Mar 19;5(3):185-93. doi: 10.1021/cn400153g. Epub 2014 Jan 23.

39.

Effect of eslicarbazepine acetate in the corneal kindling progression and the amygdala kindling model of temporal lobe epilepsy.

Potschka H, Soerensen J, Pekcec A, Loureiro A, Soares-da-Silva P.

Epilepsy Res. 2014 Feb;108(2):212-22. doi: 10.1016/j.eplepsyres.2013.11.017. Epub 2013 Dec 1.

PMID:
24345645
40.

The CNTF-derived peptide mimetic Cintrofin attenuates spatial-learning deficits in a rat post-status epilepticus model.

Russmann V, Seeger N, Zellinger C, Hadamitzky M, Pankratova S, Wendt H, Bock E, Berezin V, Potschka H.

Neurosci Lett. 2013 Nov 27;556:170-5. doi: 10.1016/j.neulet.2013.10.003. Epub 2013 Oct 11.

PMID:
24120433
41.

The novel antiepileptic drug imepitoin compares favourably to other GABA-mimetic drugs in a seizure threshold model in mice and dogs.

Löscher W, Hoffmann K, Twele F, Potschka H, Töllner K.

Pharmacol Res. 2013 Nov;77:39-46. doi: 10.1016/j.phrs.2013.09.003. Epub 2013 Sep 18.

PMID:
24056205
42.

Dynamic regulation of P-glycoprotein in human brain capillaries.

Avemary J, Salvamoser JD, Peraud A, Rémi J, Noachtar S, Fricker G, Potschka H.

Mol Pharm. 2013 Sep 3;10(9):3333-41. doi: 10.1021/mp4001102. Epub 2013 Aug 7.

PMID:
23924183
43.

[11C]quinidine and [11C]laniquidar PET imaging in a chronic rodent epilepsy model: impact of epilepsy and drug-responsiveness.

Syvänen S, Russmann V, Verbeek J, Eriksson J, Labots M, Zellinger C, Seeger N, Schuit R, Rongen M, van Kooij R, Windhorst AD, Lammertsma AA, de Lange EC, Voskuyl RA, Koepp M, Potschka H.

Nucl Med Biol. 2013 Aug;40(6):764-75. doi: 10.1016/j.nucmedbio.2013.05.008. Epub 2013 Jul 1.

PMID:
23827307
44.

CNS transporters and drug delivery in epilepsy.

Potschka H, Luna-Munguia H.

Curr Pharm Des. 2014;20(10):1534-42. Review.

PMID:
23789955
45.

Animal and human data: where are our concepts for drug-resistant epilepsy going?

Potschka H.

Epilepsia. 2013 May;54 Suppl 2:29-32. doi: 10.1111/epi.12181. Review.

46.

Lacosamide treatment following status epilepticus attenuates neuronal cell loss and alterations in hippocampal neurogenesis in a rat electrical status epilepticus model.

Licko T, Seeger N, Zellinger C, Russmann V, Matagne A, Potschka H.

Epilepsia. 2013 Jul;54(7):1176-85. doi: 10.1111/epi.12196. Epub 2013 Apr 24.

47.

Canine epilepsy as a translational model?

Potschka H, Fischer A, von Rüden EL, Hülsmeyer V, Baumgärtner W.

Epilepsia. 2013 Apr;54(4):571-9. doi: 10.1111/epi.12138. Epub 2013 Mar 18. Review.

48.

Finding a better drug for epilepsy: antiepileptogenesis targets.

Kobow K, Auvin S, Jensen F, Löscher W, Mody I, Potschka H, Prince D, Sierra A, Simonato M, Pitkänen A, Nehlig A, Rho JM.

Epilepsia. 2012 Nov;53(11):1868-76. doi: 10.1111/j.1528-1167.2012.03716.x. Epub 2012 Oct 12. Review.

49.

Animal models of drug-resistant epilepsy.

Potschka H.

Epileptic Disord. 2012 Sep;14(3):226-34. doi: 10.1684/epd.2012.0532.

50.

Pharmacoresistance.

Potschka H, Brodie MJ.

Handb Clin Neurol. 2012;108:741-57. doi: 10.1016/B978-0-444-52899-5.00025-3. Review. No abstract available.

PMID:
22939063

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