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Items: 32

1.

Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II.

Steurer B, Janssens RC, Geverts B, Geijer ME, Wienholz F, Theil AF, Chang J, Dealy S, Pothof J, van Cappellen WA, Houtsmuller AB, Marteijn JA.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4368-E4376. doi: 10.1073/pnas.1717920115. Epub 2018 Apr 9.

2.

Top 10 Myths Regarding the Diagnosis and Treatment of Cellulitis.

McCreary EK, Heim ME, Schulz LT, Hoffman R, Pothof J, Fox B.

J Emerg Med. 2017 Oct;53(4):485-492. doi: 10.1016/j.jemermed.2017.05.007. Epub 2017 Jul 3.

PMID:
28684060
3.

Description and Yield of Current Quality and Safety Review in Selected US Academic Emergency Departments.

Griffey RT, Schneider RM, Sharp BR, Pothof JJ, Hodkins S, Capp R, Wiler JL, Sreshta N, Sather JE, Sampson CS, Powell JT, Groner KY, Adler LM.

J Patient Saf. 2017 Jun 29. doi: 10.1097/PTS.0000000000000379. [Epub ahead of print]

PMID:
28661998
4.

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.

Baar MP, Brandt RMC, Putavet DA, Klein JDD, Derks KWJ, Bourgeois BRM, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB, Pothof J, de Bruin RWF, Madl T, Hoeijmakers JHJ, Campisi J, de Keizer PLJ.

Cell. 2017 Mar 23;169(1):132-147.e16. doi: 10.1016/j.cell.2017.02.031.

5.

Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice.

Vermeij WP, Dollé ME, Reiling E, Jaarsma D, Payan-Gomez C, Bombardieri CR, Wu H, Roks AJ, Botter SM, van der Eerden BC, Youssef SA, Kuiper RV, Nagarajah B, van Oostrom CT, Brandt RM, Barnhoorn S, Imholz S, Pennings JL, de Bruin A, Gyenis Á, Pothof J, Vijg J, van Steeg H, Hoeijmakers JH.

Nature. 2016 Sep 15;537(7620):427-431. doi: 10.1038/nature19329. Epub 2016 Aug 24.

6.

Top Ten Myths Regarding the Diagnosis and Treatment of Urinary Tract Infections.

Schulz L, Hoffman RJ, Pothof J, Fox B.

J Emerg Med. 2016 Jul;51(1):25-30. doi: 10.1016/j.jemermed.2016.02.009. Epub 2016 Apr 7.

PMID:
27066953
7.

miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway.

van Jaarsveld MT, van Kuijk PF, Boersma AW, Helleman J, van IJcken WF, Mathijssen RH, Pothof J, Berns EM, Verweij J, Wiemer EA.

Mol Cancer. 2015 Nov 17;14:196. doi: 10.1186/s12943-015-0464-4.

8.

Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options.

Vermeij WP, Hoeijmakers JH, Pothof J.

Annu Rev Pharmacol Toxicol. 2016;56:427-45. doi: 10.1146/annurev-pharmtox-010814-124316. Epub 2015 Oct 28. Review.

PMID:
26514200
9.

RNAome sequencing delineates the complete RNA landscape.

Derks KW, Pothof J.

Genom Data. 2015 Jul 11;5:381-4. doi: 10.1016/j.gdata.2015.07.002. eCollection 2015 Sep.

10.

Attenuated XPC expression is not associated with impaired DNA repair in bladder cancer.

Naipal KA, Raams A, Bruens ST, Brandsma I, Verkaik NS, Jaspers NG, Hoeijmakers JH, van Leenders GJ, Pothof J, Kanaar R, Boormans J, van Gent DC.

PLoS One. 2015 Apr 30;10(4):e0126029. doi: 10.1371/journal.pone.0126029. eCollection 2015.

11.

Deciphering the RNA landscape by RNAome sequencing.

Derks KW, Misovic B, van den Hout MC, Kockx CE, Gomez CP, Brouwer RW, Vrieling H, Hoeijmakers JH, van IJcken WF, Pothof J.

RNA Biol. 2015;12(1):30-42. doi: 10.1080/15476286.2015.1017202.

12.

Posterior reversible encephalopathy syndrome in the emergency department: case series and literature review.

Thompson RJ, Sharp B, Pothof J, Hamedani A.

West J Emerg Med. 2015 Jan;16(1):5-10. doi: 10.5811/westjem.2014.12.24126. Epub 2015 Jan 5. Review.

13.

Aging: not all DNA damage is equal.

Vermeij WP, Hoeijmakers JH, Pothof J.

Curr Opin Genet Dev. 2014 Jun;26:124-30. doi: 10.1016/j.gde.2014.06.006. Epub 2014 Sep 15. Review.

PMID:
25222498
14.

The DNA damage response: the omics era and its impact.

Derks KW, Hoeijmakers JH, Pothof J.

DNA Repair (Amst). 2014 Jul;19:214-20. doi: 10.1016/j.dnarep.2014.03.008. Epub 2014 Apr 30. Review.

15.

Observation and inpatient status: clinical impact of the 2-midnight rule.

Sheehy AM, Caponi B, Gangireddy S, Hamedani AG, Pothof JJ, Siegal E, Graf BK.

J Hosp Med. 2014 Apr;9(4):203-9. doi: 10.1002/jhm.2163. Epub 2014 Feb 14.

PMID:
24677628
16.

DNA damage responsive microRNAs misexpressed in human cancer modulate therapy sensitivity.

van Jaarsveld MT, Wouters MD, Boersma AW, Smid M, van Ijcken WF, Mathijssen RH, Hoeijmakers JH, Martens JW, van Laere S, Wiemer EA, Pothof J.

Mol Oncol. 2014 May;8(3):458-68. doi: 10.1016/j.molonc.2013.12.011. Epub 2013 Dec 31.

17.

In vivo murine hepatic microRNA and mRNA expression signatures predicting the (non-)genotoxic carcinogenic potential of chemicals.

Melis JP, Derks KW, Pronk TE, Wackers P, Schaap MM, Zwart E, van Ijcken WF, Jonker MJ, Breit TM, Pothof J, van Steeg H, Luijten M.

Arch Toxicol. 2014 Apr;88(4):1023-34. doi: 10.1007/s00204-013-1189-z. Epub 2014 Jan 5.

PMID:
24390151
18.

MicroRNA-Mediated Down-Regulation of M-CSF Receptor Contributes to Maturation of Mouse Monocyte-Derived Dendritic Cells.

Riepsaame J, van Oudenaren A, den Broeder BJ, van Ijcken WF, Pothof J, Leenen PJ.

Front Immunol. 2013 Oct 30;4:353. doi: 10.3389/fimmu.2013.00353. eCollection 2013.

19.

Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures.

van Spronsen M, van Battum EY, Kuijpers M, Vangoor VR, Rietman ML, Pothof J, Gumy LF, van Ijcken WF, Akhmanova A, Pasterkamp RJ, Hoogenraad CC.

PLoS One. 2013 Oct 3;8(10):e74907. doi: 10.1371/journal.pone.0074907. eCollection 2013.

20.

BACH2: a marker of DNA damage and ageing.

Uittenboogaard LM, Payan-Gomez C, Pothof J, van Ijcken W, Mastroberardino PG, van der Pluijm I, Hoeijmakers JH, Tresini M.

DNA Repair (Amst). 2013 Nov;12(11):982-92. doi: 10.1016/j.dnarep.2013.08.016. Epub 2013 Sep 24.

21.

miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells.

van Jaarsveld MT, Helleman J, Boersma AW, van Kuijk PF, van Ijcken WF, Despierre E, Vergote I, Mathijssen RH, Berns EM, Verweij J, Pothof J, Wiemer EA.

Oncogene. 2013 Sep 5;32(36):4284-93. doi: 10.1038/onc.2012.433. Epub 2012 Oct 8.

PMID:
23045278
22.

The kinase RSK2 modulates the sensitivity of ovarian cancer cells to cisplatin.

van Jaarsveld MT, Blijdorp IC, Boersma AW, Pothof J, Mathijssen RH, Verweij J, Wiemer EA.

Eur J Cancer. 2013 Jan;49(2):345-51. doi: 10.1016/j.ejca.2012.08.024. Epub 2012 Oct 4.

PMID:
23041051
23.

Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing.

Gombar S, Jung HJ, Dong F, Calder B, Atzmon G, Barzilai N, Tian XL, Pothof J, Hoeijmakers JH, Campisi J, Vijg J, Suh Y.

BMC Genomics. 2012 Jul 31;13:353. doi: 10.1186/1471-2164-13-353.

24.

Spatiotemporal aspects of MicroRNA-mediated gene regulation.

Pothof J, van Gent DC.

Adv Exp Med Biol. 2011;722:75-85. doi: 10.1007/978-1-4614-0332-6_5. Review.

PMID:
21915783
25.

MicroRNAs, the DNA damage response and cancer.

Wouters MD, van Gent DC, Hoeijmakers JH, Pothof J.

Mutat Res. 2011 Dec 1;717(1-2):54-66. doi: 10.1016/j.mrfmmm.2011.03.012. Epub 2011 Apr 6. Review.

PMID:
21477600
26.

3rd US-EU workshop: systems level understanding of DNA damage responses.

Sander M, Begley TJ, Desaintes C, Gavin AC, Pelroy R, Pothof J, Shiloh Y, van Gent D, Van Houten B, Yaffe M, Mullenders L.

Mutat Res. 2010 Oct 13;692(1-2):53-60. doi: 10.1016/j.mrfmmm.2010.07.012. Epub 2010 Aug 19.

27.

MicroRNA responses and stress granule formation modulate the DNA damage response.

Pothof J, Verkaik NS, Hoeijmakers JH, van Gent DC.

Cell Cycle. 2009 Nov 1;8(21):3462-8. Epub 2009 Nov 17.

PMID:
19823042
28.

MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response.

Pothof J, Verkaik NS, van IJcken W, Wiemer EA, Ta VT, van der Horst GT, Jaspers NG, van Gent DC, Hoeijmakers JH, Persengiev SP.

EMBO J. 2009 Jul 22;28(14):2090-9. doi: 10.1038/emboj.2009.156. Epub 2009 Jun 18.

29.

Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi.

van Haaften G, Romeijn R, Pothof J, Koole W, Mullenders LH, Pastink A, Plasterk RH, Tijsterman M.

Curr Biol. 2006 Jul 11;16(13):1344-50.

30.

Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation.

Bakkers J, Kramer C, Pothof J, Quaedvlieg NE, Spaink HP, Hammerschmidt M.

Development. 2004 Feb;131(3):525-37.

31.

Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi.

Pothof J, van Haaften G, Thijssen K, Kamath RS, Fraser AG, Ahringer J, Plasterk RH, Tijsterman M.

Genes Dev. 2003 Feb 15;17(4):443-8.

32.

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