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Items: 1 to 50 of 71

1.

Cyclic Ozone Exposure Induces Gender-Dependent Neuropathology and Memory Decline in an Animal Model of Alzheimer's Disease.

Akhter H, Ballinger C, Liu N, van Groen T, Postlethwait EM, Liu RM.

Toxicol Sci. 2015 Sep;147(1):222-34. doi: 10.1093/toxsci/kfv124. Epub 2015 Jun 26.

2.

Convergence of biological nitration and nitrosation via symmetrical nitrous anhydride.

Vitturi DA, Minarrieta L, Salvatore SR, Postlethwait EM, Fazzari M, Ferrer-Sueta G, Lancaster JR Jr, Freeman BA, Schopfer FJ.

Nat Chem Biol. 2015 Jul;11(7):504-10. doi: 10.1038/nchembio.1814. Epub 2015 May 25.

3.

Ozone inhalation modifies the rat liver proteome.

Theis WS, Andringa KK, Millender-Swain T, Dickinson DA, Postlethwait EM, Bailey SM.

Redox Biol. 2014;2:52-60. doi: 10.1016/j.redox.2013.11.006. Epub 2013 Nov 28.

4.

Early life ozone exposure results in dysregulated innate immune function and altered microRNA expression in airway epithelium.

Clay CC, Maniar-Hew K, Gerriets JE, Wang TT, Postlethwait EM, Evans MJ, Fontaine JH, Miller LA.

PLoS One. 2014 Mar 4;9(3):e90401. doi: 10.1371/journal.pone.0090401. eCollection 2014.

5.

Innate immune response to LPS in airway epithelium is dependent on chronological age and antecedent exposures.

Maniar-Hew K, Clay CC, Postlethwait EM, Evans MJ, Fontaine JH, Miller LA.

Am J Respir Cell Mol Biol. 2013 Nov;49(5):710-20. doi: 10.1165/rcmb.2012-0321OC.

6.

Site-specific dynamics of CD11b+ and CD103+ dendritic cell accumulations following ozone exposure.

Brand JD, Ballinger CA, Tuggle KL, Fanucchi MV, Schwiebert LM, Postlethwait EM.

Am J Physiol Lung Cell Mol Physiol. 2012 Dec 15;303(12):L1079-86. doi: 10.1152/ajplung.00185.2012. Epub 2012 Oct 19.

7.

Administration of nitrite after chlorine gas exposure prevents lung injury: effect of administration modality.

Samal AA, Honavar J, Brandon A, Bradley KM, Doran S, Liu Y, Dunaway C, Steele C, Postlethwait EM, Squadrito GL, Fanucchi MV, Matalon S, Patel RP.

Free Radic Biol Med. 2012 Oct 1;53(7):1431-9. doi: 10.1016/j.freeradbiomed.2012.08.007. Epub 2012 Aug 11.

8.

Desferrioxamine inhibits protein tyrosine nitration: mechanisms and implications.

Adgent MA, Squadrito GL, Ballinger CA, Krzywanski DM, Lancaster JR, Postlethwait EM.

Free Radic Biol Med. 2012 Aug 15;53(4):951-61. doi: 10.1016/j.freeradbiomed.2012.06.003. Epub 2012 Jun 15.

9.

Transforming growth factor β suppresses glutamate-cysteine ligase gene expression and induces oxidative stress in a lung fibrosis model.

Liu RM, Vayalil PK, Ballinger C, Dickinson DA, Huang WT, Wang S, Kavanagh TJ, Matthews QL, Postlethwait EM.

Free Radic Biol Med. 2012 Aug 1;53(3):554-63. doi: 10.1016/j.freeradbiomed.2012.05.016. Epub 2012 May 23.

10.

Comparative computational modeling of airflows and vapor dosimetry in the respiratory tracts of rat, monkey, and human.

Corley RA, Kabilan S, Kuprat AP, Carson JP, Minard KR, Jacob RE, Timchalk C, Glenny R, Pipavath S, Cox T, Wallis CD, Larson RF, Fanucchi MV, Postlethwait EM, Einstein DR.

Toxicol Sci. 2012 Aug;128(2):500-16. doi: 10.1093/toxsci/kfs168. Epub 2012 May 12.

11.

Branch-based model for the diameters of the pulmonary airways: accounting for departures from self-consistency and registration errors.

Neradilek MB, Polissar NL, Einstein DR, Glenny RW, Minard KR, Carson JP, Jiao X, Jacob RE, Cox TC, Postlethwait EM, Corley RA.

Anat Rec (Hoboken). 2012 Jun;295(6):1027-44. doi: 10.1002/ar.22476. Epub 2012 Apr 24.

12.

Metabolic and cardiac signaling effects of inhaled hydrogen sulfide and low oxygen in male rats.

Stein A, Mao Z, Morrison JP, Fanucchi MV, Postlethwait EM, Patel RP, Kraus DW, Doeller JE, Bailey SM.

J Appl Physiol (1985). 2012 May;112(10):1659-69. doi: 10.1152/japplphysiol.01598.2011. Epub 2012 Mar 8.

13.

Targeted aerosolized delivery of ascorbate in the lungs of chlorine-exposed rats.

Bracher A, Doran SF, Squadrito GL, Postlethwait EM, Bowen L, Matalon S.

J Aerosol Med Pulm Drug Deliv. 2012 Dec;25(6):333-41. doi: 10.1089/jamp.2011.0963. Epub 2012 Mar 6.

14.

Asbestos in public hospitals: are employees at risk?

Scarlett HP, Postlethwait E, Delzell E, Sathiakumar N, Oestenstad RK.

J Environ Health. 2012 Jan-Feb;74(6):22-6.

PMID:
22329205
15.

Post-exposure antioxidant treatment in rats decreases airway hyperplasia and hyperreactivity due to chlorine inhalation.

Fanucchi MV, Bracher A, Doran SF, Squadrito GL, Fernandez S, Postlethwait EM, Bowen L, Matalon S.

Am J Respir Cell Mol Biol. 2012 May;46(5):599-606. doi: 10.1165/rcmb.2011-0196OC. Epub 2011 Dec 8.

16.

Exposure to airborne asbestos in Jamaican hospitals.

Scarlett HP, Delzell E, Sathiakumar N, Oestenstad RK, Postlethwait E.

West Indian Med J. 2010 Dec;59(6):668-73.

PMID:
21702240
17.

Increased transforming growth factor beta 1 expression mediates ozone-induced airway fibrosis in mice.

Katre A, Ballinger C, Akhter H, Fanucchi M, Kim DK, Postlethwait E, Liu RM.

Inhal Toxicol. 2011 Jul;23(8):486-94. doi: 10.3109/08958378.2011.584919.

18.

Mitigation of chlorine gas lung injury in rats by postexposure administration of sodium nitrite.

Yadav AK, Doran SF, Samal AA, Sharma R, Vedagiri K, Postlethwait EM, Squadrito GL, Fanucchi MV, Roberts LJ 2nd, Patel RP, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L362-9. doi: 10.1152/ajplung.00278.2010. Epub 2010 Dec 10.

19.

Chlorine gas exposure causes systemic endothelial dysfunction by inhibiting endothelial nitric oxide synthase-dependent signaling.

Honavar J, Samal AA, Bradley KM, Brandon A, Balanay J, Squadrito GL, MohanKumar K, Maheshwari A, Postlethwait EM, Matalon S, Patel RP.

Am J Respir Cell Mol Biol. 2011 Aug;45(2):419-25. doi: 10.1165/rcmb.2010-0151OC. Epub 2010 Dec 3.

20.

Ascorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in mice.

Zarogiannis SG, Jurkuvenaite A, Fernandez S, Doran SF, Yadav AK, Squadrito GL, Postlethwait EM, Bowen L, Matalon S.

Am J Respir Cell Mol Biol. 2011 Aug;45(2):386-92. doi: 10.1165/rcmb.2010-0432OC. Epub 2010 Dec 3.

21.

Persistent rhinitis and epithelial remodeling induced by cyclic ozone exposure in the nasal airways of infant monkeys.

Carey SA, Ballinger CA, Plopper CG, McDonald RJ, Bartolucci AA, Postlethwait EM, Harkema JR.

Am J Physiol Lung Cell Mol Physiol. 2011 Feb;300(2):L242-54. doi: 10.1152/ajplung.00177.2010. Epub 2010 Dec 3.

22.

Postnatal episodic ozone results in persistent attenuation of pulmonary and peripheral blood responses to LPS challenge.

Maniar-Hew K, Postlethwait EM, Fanucchi MV, Ballinger CA, Evans MJ, Harkema JR, Carey SA, McDonald RJ, Bartolucci AA, Miller LA.

Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L462-71. doi: 10.1152/ajplung.00254.2010. Epub 2010 Dec 3.

23.

Mechanisms and modification of chlorine-induced lung injury in animals.

Yadav AK, Bracher A, Doran SF, Leustik M, Squadrito GL, Postlethwait EM, Matalon S.

Proc Am Thorac Soc. 2010 Jul;7(4):278-83. doi: 10.1513/pats.201001-009SM. Review.

24.

Exposing animals to oxidant gases: nose only vs. whole body.

Cheng YS, Bowen L, Rando RJ, Postlethwait EM, Squadrito GL, Matalon S.

Proc Am Thorac Soc. 2010 Jul;7(4):264-8. doi: 10.1513/pats.201001-001SM.

25.

Elucidating mechanisms of chlorine toxicity: reaction kinetics, thermodynamics, and physiological implications.

Squadrito GL, Postlethwait EM, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2010 Sep;299(3):L289-300. doi: 10.1152/ajplung.00077.2010. Epub 2010 Jun 4. Review.

26.

Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts.

Liu RM, Choi J, Wu JH, Gaston Pravia KA, Lewis KM, Brand JD, Mochel NS, Krzywanski DM, Lambeth JD, Hagood JS, Forman HJ, Thannickal VJ, Postlethwait EM.

J Biol Chem. 2010 May 21;285(21):16239-47. doi: 10.1074/jbc.M110.111732. Epub 2010 Mar 12.

27.

On the hydrophobicity of nitrogen dioxide: could there be a "lens" effect for NO(2) reaction kinetics?

Squadrito GL, Postlethwait EM.

Nitric Oxide. 2009 Sep;21(2):104-9. doi: 10.1016/j.niox.2009.05.008. Epub 2009 Jun 18.

28.

Pulmonary ozone exposure induces vascular dysfunction, mitochondrial damage, and atherogenesis.

Chuang GC, Yang Z, Westbrook DG, Pompilius M, Ballinger CA, White CR, Krzywanski DM, Postlethwait EM, Ballinger SW.

Am J Physiol Lung Cell Mol Physiol. 2009 Aug;297(2):L209-16. doi: 10.1152/ajplung.00102.2009. Epub 2009 Apr 24.

29.

Mitigation of chlorine-induced lung injury by low-molecular-weight antioxidants.

Leustik M, Doran S, Bracher A, Williams S, Squadrito GL, Schoeb TR, Postlethwait E, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2008 Nov;295(5):L733-43. doi: 10.1152/ajplung.90240.2008. Epub 2008 Aug 15.

30.

Panel discussion review: session four--assessing biological plausibility of epidemiological findings in air pollution research.

Brown JS, Graham JA, Chen LC, Postlethwait EM, Ghio AJ, Foster WM, Gordon T.

J Expo Sci Environ Epidemiol. 2007 Dec;17 Suppl 2:S97-105. doi: 10.1038/sj.jes.7500632.

PMID:
18079771
31.

Glutathione suppresses TGF-beta-induced PAI-1 expression by inhibiting p38 and JNK MAPK and the binding of AP-1, SP-1, and Smad to the PAI-1 promoter.

Vayalil PK, Iles KE, Choi J, Yi AK, Postlethwait EM, Liu RM.

Am J Physiol Lung Cell Mol Physiol. 2007 Nov;293(5):L1281-92. Epub 2007 Sep 21.

32.

Scavenger receptors clear the air.

Postlethwait EM.

J Clin Invest. 2007 Mar;117(3):601-4.

33.

Three-dimensional mapping of ozone-induced injury in the nasal airways of monkeys using magnetic resonance imaging and morphometric techniques.

Carey SA, Minard KR, Trease LL, Wagner JG, Garcia GJ, Ballinger CA, Kimbell JS, Plopper CG, Corley RA, Postlethwait EM, Harkema JR, Einstein DR.

Toxicol Pathol. 2007 Jan;35(1):27-40. Erratum in: Toxicol Pathol. 2007;35(4):620. Einstein, Daniel R [added].

PMID:
17325970
34.

gamma-Glutamyl transpeptidase is induced by 4-hydroxynonenal via EpRE/Nrf2 signaling in rat epithelial type II cells.

Zhang H, Liu H, Dickinson DA, Liu RM, Postlethwait EM, Laperche Y, Forman HJ.

Free Radic Biol Med. 2006 Apr 15;40(8):1281-92. Epub 2005 Dec 1.

35.

Glutathione restores collagen degradation in TGF-beta-treated fibroblasts by blocking plasminogen activator inhibitor-1 expression and activating plasminogen.

Vayalil PK, Olman M, Murphy-Ullrich JE, Postlethwait EM, Liu RM.

Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L937-45. Epub 2005 Oct 28.

36.

4-Hydroxynonenal induces rat gamma-glutamyl transpeptidase through mitogen-activated protein kinase-mediated electrophile response element/nuclear factor erythroid 2-related factor 2 signaling.

Zhang H, Liu H, Iles KE, Liu RM, Postlethwait EM, Laperche Y, Forman HJ.

Am J Respir Cell Mol Biol. 2006 Feb;34(2):174-81. Epub 2005 Sep 29.

37.

Antioxidant-mediated augmentation of ozone-induced membrane oxidation.

Ballinger CA, Cueto R, Squadrito G, Coffin JF, Velsor LW, Pryor WA, Postlethwait EM.

Free Radic Biol Med. 2005 Feb 15;38(4):515-26.

PMID:
15649654
38.

Prenatal environmental tobacco smoke exposure promotes adult atherogenesis and mitochondrial damage in apolipoprotein E-/- mice fed a chow diet.

Yang Z, Knight CA, Mamerow MM, Vickers K, Penn A, Postlethwait EM, Ballinger SW.

Circulation. 2004 Dec 14;110(24):3715-20. Epub 2004 Nov 29.

PMID:
15569831
39.

Interfacial phospholipids inhibit ozone-reactive absorption-mediated cytotoxicity in vitro.

Connor LM, Ballinger CA, Albrecht TB, Postlethwait EM.

Am J Physiol Lung Cell Mol Physiol. 2004 Jun;286(6):L1169-78. Epub 2004 Jan 16.

40.

A model of sensitivity: 1,3-butadiene increases mutant frequencies and genomic damage in mice lacking a functional microsomal epoxide hydrolase gene.

Wickliffe JK, Ammenheuser MM, Salazar JJ, Abdel-Rahman SZ, Hastings-Smith DA, Postlethwait EM, Lloyd RS, Ward JB Jr.

Environ Mol Mutagen. 2003;42(2):106-10.

PMID:
12929123
41.

Influence of epithelial lining fluid lipids on NO(2)-induced membrane oxidation and nitration.

Velsor LW, Ballinger CA, Patel J, Postlethwait EM.

Free Radic Biol Med. 2003 Mar 15;34(6):720-33.

PMID:
12633749
42.

CCL7 and CXCL10 orchestrate oxidative stress-induced neutrophilic lung inflammation.

Michalec L, Choudhury BK, Postlethwait E, Wild JS, Alam R, Lett-Brown M, Sur S.

J Immunol. 2002 Jan 15;168(2):846-52.

43.

NO2 interfacial transfer is reduced by phospholipid monolayers.

Connor LM, Bidani A, Goerke J, Clements JA, Postlethwait EM.

J Appl Physiol (1985). 2001 Nov;91(5):2024-34.

44.

Effect of respiratory pattern on ozone injury to the airways of isolated rat lungs.

Joad JP, Bric JM, Weir AJ, Putney L, Hyde DM, Postlethwait EM, Plopper CG.

Toxicol Appl Pharmacol. 2000 Nov 15;169(1):26-32.

PMID:
11076693
45.

Three-dimensional mapping of ozone-induced acute cytotoxicity in tracheobronchial airways of isolated perfused rat lung.

Postlethwait EM, Joad JP, Hyde DM, Schelegle ES, Bric JM, Weir AJ, Putney LF, Wong VJ, Velsor LW, Plopper CG.

Am J Respir Cell Mol Biol. 2000 Feb;22(2):191-9.

PMID:
10657940
46.

Nitric oxide-induced reduction of lung cell and whole lung thioredoxin expression is regulated by NF-kappaB.

Zhang J, Velsor LW, Patel JM, Postlethwait EM, Block ER.

Am J Physiol. 1999 Oct;277(4):L787-93. doi: 10.1152/ajplung.1999.277.4.L787.

PMID:
10516220
47.

O3-induced formation of bioactive lipids: estimated surface concentrations and lining layer effects.

Postlethwait EM, Cueto R, Velsor LW, Pryor WA.

Am J Physiol. 1998 Jun;274(6):L1006-16. doi: 10.1152/ajplung.1998.274.6.L1006.

PMID:
9609740
48.

NO2-induced generation of extracellular reactive oxygen is mediated by epithelial lining layer antioxidants.

Velsor LW, Postlethwait EM.

Am J Physiol. 1997 Dec;273(6):L1265-75. doi: 10.1152/ajplung.1997.273.6.L1265.

PMID:
9435583
49.

NO2 reactive absorption substrates in rat pulmonary surface lining fluids.

Postlethwait EM, Langford SD, Jacobson LM, Bidani A.

Free Radic Biol Med. 1995 Nov;19(5):553-63.

PMID:
8529914
50.

Ozone-reactive absorption by pulmonary epithelial lining fluid constituents.

Langford SD, Bidani A, Postlethwait EM.

Toxicol Appl Pharmacol. 1995 May;132(1):122-30.

PMID:
7747275

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