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Items: 1 to 50 of 131

1.

Insight into erythrocyte phospholipid molecular flux in healthy humans and in patients with acute respiratory distress syndrome.

Dushianthan A, Cusack R, Koster G, Grocott MPW, Postle AD.

PLoS One. 2019 Aug 27;14(8):e0221595. doi: 10.1371/journal.pone.0221595. eCollection 2019.

2.

Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers.

Brandsma J, Goss VM, Yang X, Bakke PS, Caruso M, Chanez P, Dahlén SE, Fowler SJ, Horvath I, Krug N, Montuschi P, Sanak M, Sandström T, Shaw DE, Chung KF, Singer F, Fleming LJ, Sousa AR, Pandis I, Bansal AT, Sterk PJ, Djukanović R, Postle AD; U-BIOPRED Study Group.

Metabolomics. 2018 Sep 17;14(10):123. doi: 10.1007/s11306-018-1412-2.

3.

Increased surfactant protein-D levels in the airways of preterm neonates with sepsis indicated responses to infectious challenges.

Mackay RA, Townsend JP, Calvert J, Anthony M, Wilkinson AR, Postle AD, Clark HW, Todd DA.

Acta Paediatr. 2019 May;108(5):870-876. doi: 10.1111/apa.14630. Epub 2019 Jan 8.

4.

Metabolism of a synthetic compared with a natural therapeutic pulmonary surfactant in adult mice.

Madsen J, Panchal MH, Mackay RA, Echaide M, Koster G, Aquino G, Pelizzi N, Perez-Gil J, Salomone F, Clark HW, Postle AD.

J Lipid Res. 2018 Oct;59(10):1880-1892. doi: 10.1194/jlr.M085431. Epub 2018 Aug 14.

5.

Abnormal liver phosphatidylcholine synthesis revealed in patients with acute respiratory distress syndrome.

Dushianthan A, Cusack R, Grocott MPW, Postle AD.

J Lipid Res. 2018 Jun;59(6):1034-1045. doi: 10.1194/jlr.P085050. Epub 2018 May 1.

6.

A robust and versatile mass spectrometry platform for comprehensive assessment of the thiol redox metabolome.

Sutton TR, Minnion M, Barbarino F, Koster G, Fernandez BO, Cumpstey AF, Wischmann P, Madhani M, Frenneaux MP, Postle AD, Cortese-Krott MM, Feelisch M.

Redox Biol. 2018 Jun;16:359-380. doi: 10.1016/j.redox.2018.02.012. Epub 2018 Feb 19.

7.

Lipidomics of Thalassiosira pseudonana under Phosphorus Stress Reveal Underlying Phospholipid Substitution Dynamics and Novel Diglycosylceramide Substitutes.

Hunter JE, Brandsma J, Dymond MK, Koster G, Moore CM, Postle AD, Mills RA, Attard GS.

Appl Environ Microbiol. 2018 Mar 1;84(6). pii: e02034-17. doi: 10.1128/AEM.02034-17. Print 2018 Mar 15.

8.

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.

Bowden JA, Heckert A, Ulmer CZ, Jones CM, Koelmel JP, Abdullah L, Ahonen L, Alnouti Y, Armando AM, Asara JM, Bamba T, Barr JR, Bergquist J, Borchers CH, Brandsma J, Breitkopf SB, Cajka T, Cazenave-Gassiot A, Checa A, Cinel MA, Colas RA, Cremers S, Dennis EA, Evans JE, Fauland A, Fiehn O, Gardner MS, Garrett TJ, Gotlinger KH, Han J, Huang Y, Neo AH, Hyötyläinen T, Izumi Y, Jiang H, Jiang H, Jiang J, Kachman M, Kiyonami R, Klavins K, Klose C, Köfeler HC, Kolmert J, Koal T, Koster G, Kuklenyik Z, Kurland IJ, Leadley M, Lin K, Maddipati KR, McDougall D, Meikle PJ, Mellett NA, Monnin C, Moseley MA, Nandakumar R, Oresic M, Patterson R, Peake D, Pierce JS, Post M, Postle AD, Pugh R, Qiu Y, Quehenberger O, Ramrup P, Rees J, Rembiesa B, Reynaud D, Roth MR, Sales S, Schuhmann K, Schwartzman ML, Serhan CN, Shevchenko A, Somerville SE, St John-Williams L, Surma MA, Takeda H, Thakare R, Thompson JW, Torta F, Triebl A, Trötzmüller M, Ubhayasekera SJK, Vuckovic D, Weir JM, Welti R, Wenk MR, Wheelock CE, Yao L, Yuan M, Zhao XH, Zhou S.

J Lipid Res. 2017 Dec;58(12):2275-2288. doi: 10.1194/jlr.M079012. Epub 2017 Oct 6.

9.

Hepatic Steatosis Accompanies Pulmonary Alveolar Proteinosis.

Hunt AN, Malur A, Monfort T, Lagoudakis P, Mahajan S, Postle AD, Thomassen MJ.

Am J Respir Cell Mol Biol. 2017 Oct;57(4):448-458. doi: 10.1165/rcmb.2016-0242OC.

10.

Analysis of the regulation of surfactant phosphatidylcholine metabolism using stable isotopes.

Brandsma J, Postle AD.

Ann Anat. 2017 May;211:176-183. doi: 10.1016/j.aanat.2017.02.008. Epub 2017 Mar 25. Review.

PMID:
28351529
11.

Stable isotope analysis of dynamic lipidomics.

Brandsma J, Bailey AP, Koster G, Gould AP, Postle AD.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Aug;1862(8):792-796. doi: 10.1016/j.bbalip.2017.03.002. Epub 2017 Mar 14. Review.

PMID:
28302590
12.

Rapid test for lung maturity, based on spectroscopy of gastric aspirate, predicted respiratory distress syndrome with high sensitivity.

Verder H, Heiring C, Clark H, Sweet D, Jessen TE, Ebbesen F, Björklund LJ, Andreasson B, Bender L, Bertelsen A, Dahl M, Eschen C, Fenger-Grøn J, Hoffmann SF, Höskuldsson A, Bruusgaard-Mouritsen M, Lundberg F, Postle AD, Schousboe P, Schmidt P, Stanchev H, Sørensen L.

Acta Paediatr. 2017 Mar;106(3):430-437. doi: 10.1111/apa.13683. Epub 2016 Dec 20.

13.

Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.

Mansour S, Tocheva AS, Cave-Ayland C, Machelett MM, Sander B, Lissin NM, Molloy PE, Baird MS, Stübs G, Schröder NW, Schumann RR, Rademann J, Postle AD, Jakobsen BK, Marshall BG, Gosain R, Elkington PT, Elliott T, Skylaris CK, Essex JW, Tews I, Gadola SD.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1266-75. doi: 10.1073/pnas.1519246113. Epub 2016 Feb 16.

14.

Lipid remodelling is a widespread strategy in marine heterotrophic bacteria upon phosphorus deficiency.

Sebastián M, Smith AF, González JM, Fredricks HF, Van Mooy B, Koblížek M, Brandsma J, Koster G, Mestre M, Mostajir B, Pitta P, Postle AD, Sánchez P, Gasol JM, Scanlan DJ, Chen Y.

ISME J. 2016 Apr;10(4):968-78. doi: 10.1038/ismej.2015.172. Epub 2015 Nov 13.

15.

Antioxidant Role for Lipid Droplets in a Stem Cell Niche of Drosophila.

Bailey AP, Koster G, Guillermier C, Hirst EM, MacRae JI, Lechene CP, Postle AD, Gould AP.

Cell. 2015 Oct 8;163(2):340-53. doi: 10.1016/j.cell.2015.09.020.

16.

Ready-to-use therapeutic food with elevated n-3 polyunsaturated fatty acid content, with or without fish oil, to treat severe acute malnutrition: a randomized controlled trial.

Jones KD, Ali R, Khasira MA, Odera D, West AL, Koster G, Akomo P, Talbert AW, Goss VM, Ngari M, Thitiri J, Ndoro S, Knight MA, Omollo K, Ndungu A, Mulongo MM, Bahwere P, Fegan G, Warner JO, Postle AD, Collins S, Calder PC, Berkley JA.

BMC Med. 2015 Apr 23;13:93. doi: 10.1186/s12916-015-0315-6.

17.

Altered molecular specificity of surfactant phosphatidycholine synthesis in patients with acute respiratory distress syndrome.

Dushianthan A, Goss V, Cusack R, Grocott MP, Postle AD.

Respir Res. 2014 Nov 7;15:128. doi: 10.1186/s12931-014-0128-8.

18.

Phospholipid composition and kinetics in different endobronchial fractions from healthy volunteers.

Dushianthan A, Goss V, Cusack R, Grocott MP, Postle AD.

BMC Pulm Med. 2014 Feb 1;14:10. doi: 10.1186/1471-2466-14-10.

19.

Cell cycle dependent changes in membrane stored curvature elastic energy: evidence from lipidomic studies.

Hague CV, Postle AD, Attard GS, Dymond MK.

Faraday Discuss. 2013;161:481-97; discussion 563-89.

PMID:
23805754
20.

Muscle phospholipid hydrolysis by Bothrops asper Asp49 and Lys49 phospholipase A₂ myotoxins--distinct mechanisms of action.

Fernández J, Caccin P, Koster G, Lomonte B, Gutiérrez JM, Montecucco C, Postle AD.

FEBS J. 2013 Aug;280(16):3878-86. doi: 10.1111/febs.12386. Epub 2013 Jul 12.

21.

Application of 'omics technologies to biomarker discovery in inflammatory lung diseases.

Wheelock CE, Goss VM, Balgoma D, Nicholas B, Brandsma J, Skipp PJ, Snowden S, Burg D, D'Amico A, Horvath I, Chaiboonchoe A, Ahmed H, Ballereau S, Rossios C, Chung KF, Montuschi P, Fowler SJ, Adcock IM, Postle AD, Dahlén SE, Rowe A, Sterk PJ, Auffray C, Djukanovic R; U-BIOPRED Study Group.

Eur Respir J. 2013 Sep;42(3):802-25. doi: 10.1183/09031936.00078812. Epub 2013 Feb 8. Review.

22.

An in vivo ratio control mechanism for phospholipid homeostasis: evidence from lipidomic studies.

Dymond MK, Hague CV, Postle AD, Attard GS.

J R Soc Interface. 2012 Dec 19;10(80):20120854. doi: 10.1098/rsif.2012.0854. Print 2013 Mar 6.

23.

Regulation of lung surfactant phospholipid synthesis and metabolism.

Goss V, Hunt AN, Postle AD.

Biochim Biophys Acta. 2013 Feb;1831(2):448-58. doi: 10.1016/j.bbalip.2012.11.009. Epub 2012 Nov 27. Review.

PMID:
23200861
24.

Clinical review: Exogenous surfactant therapy for acute lung injury/acute respiratory distress syndrome--where do we go from here?

Dushianthan A, Cusack R, Goss V, Postle AD, Grocott MP.

Crit Care. 2012 Nov 22;16(6):238. doi: 10.1186/cc11512. Review.

25.

Lipidomic profiling in Crohn's disease: abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition.

Sewell GW, Hannun YA, Han X, Koster G, Bielawski J, Goss V, Smith PJ, Rahman FZ, Vega R, Bloom SL, Walker AP, Postle AD, Segal AW.

Int J Biochem Cell Biol. 2012 Nov;44(11):1839-46. doi: 10.1016/j.biocel.2012.06.016. Epub 2012 Jun 19.

26.

Lipidomics.

Postle AD.

Curr Opin Clin Nutr Metab Care. 2012 Mar;15(2):127-33. doi: 10.1097/MCO.0b013e32834fb003. Review.

PMID:
22316558
27.

Activation of sterol-response element-binding proteins (SREBP) in alveolar type II cells enhances lipogenesis causing pulmonary lipotoxicity.

Plantier L, Besnard V, Xu Y, Ikegami M, Wert SE, Hunt AN, Postle AD, Whitsett JA.

J Biol Chem. 2012 Mar 23;287(13):10099-114. doi: 10.1074/jbc.M111.303669. Epub 2012 Jan 20.

28.

Acute respiratory distress syndrome and acute lung injury.

Dushianthan A, Grocott MP, Postle AD, Cusack R.

Postgrad Med J. 2011 Sep;87(1031):612-22. doi: 10.1136/pgmj.2011.118398. Epub 2011 Jun 4. Review.

PMID:
21642654
29.

Analysis of lung surfactant phosphatidylcholine metabolism in transgenic mice using stable isotopes.

Postle AD, Henderson NG, Koster G, Clark HW, Hunt AN.

Chem Phys Lipids. 2011 Sep;164(6):549-55. doi: 10.1016/j.chemphyslip.2011.04.004. Epub 2011 Apr 15.

PMID:
21515243
30.

Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo.

Pynn CJ, Henderson NG, Clark H, Koster G, Bernhard W, Postle AD.

J Lipid Res. 2011 Feb;52(2):399-407. doi: 10.1194/jlr.D011916. Epub 2010 Nov 10.

31.

Recent advances in alveolar biology: some new looks at the alveolar interface.

Possmayer F, Hall SB, Haller T, Petersen NO, Zuo YY, Bernardino de la Serna J, Postle AD, Veldhuizen RA, Orgeig S.

Respir Physiol Neurobiol. 2010 Aug 31;173 Suppl:S55-64. doi: 10.1016/j.resp.2010.02.014. Epub 2010 Mar 4. Review.

PMID:
20206718
32.

Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice.

Besnard V, Matsuzaki Y, Clark J, Xu Y, Wert SE, Ikegami M, Stahlman MT, Weaver TE, Hunt AN, Postle AD, Whitsett JA.

Am J Physiol Lung Cell Mol Physiol. 2010 May;298(5):L646-59. doi: 10.1152/ajplung.00409.2009. Epub 2010 Feb 26.

33.

Mass spectrometry analysis of the phospholipase A(2) activity of snake pre-synaptic neurotoxins in cultured neurons.

Paoli M, Rigoni M, Koster G, Rossetto O, Montecucco C, Postle AD.

J Neurochem. 2009 Nov;111(3):737-44. doi: 10.1111/j.1471-4159.2009.06365.x. Epub 2009 Aug 27.

34.

Surfactant phospholipids, surfactant proteins, and inflammatory markers during acute lung injury in children.

Todd DA, Marsh MJ, George A, Henderson NG, Barr H, Sebastian S, Clark GT, Koster G, Clark HW, Postle AD.

Pediatr Crit Care Med. 2010 Jan;11(1):82-91. doi: 10.1097/PCC.0b013e3181ae5a4c.

PMID:
19550365
35.

Dynamic lipidomics with stable isotope labelling.

Postle AD, Hunt AN.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Sep 15;877(26):2716-21. doi: 10.1016/j.jchromb.2009.03.046. Epub 2009 Apr 5. Review.

PMID:
19395321
36.

Deletion of Scap in alveolar type II cells influences lung lipid homeostasis and identifies a compensatory role for pulmonary lipofibroblasts.

Besnard V, Wert SE, Stahlman MT, Postle AD, Xu Y, Ikegami M, Whitsett JA.

J Biol Chem. 2009 Feb 6;284(6):4018-30. doi: 10.1074/jbc.M805388200. Epub 2008 Dec 11.

37.

Testing the hypothesis that amphiphilic antineoplastic lipid analogues act through reduction of membrane curvature elastic stress.

Dymond M, Attard G, Postle AD.

J R Soc Interface. 2008 Nov 6;5(28):1371-86. doi: 10.1098/rsif.2008.0041.

38.

Electrospray ionization mass spectrometry identifies substrates and products of lipoprotein-associated phospholipase A2 in oxidized human low density lipoprotein.

Davis B, Koster G, Douet LJ, Scigelova M, Woffendin G, Ward JM, Smith A, Humphries J, Burnand KG, Macphee CH, Postle AD.

J Biol Chem. 2008 Mar 7;283(10):6428-37. doi: 10.1074/jbc.M709970200. Epub 2007 Dec 29.

39.

Diclofenac mediated derangement of neuroblastoma cell lipidomic profiles is accompanied by increased phosphatidylcholine biosynthesis.

Hunt AN, Macken M, Koster G, Kohler JA, Postle AD.

Adv Enzyme Regul. 2008;48:74-87. Epub 2007 Nov 19. No abstract available.

PMID:
18157948
40.

Lipidomic analysis of signaling pathways.

Wakelam MJ, Pettitt TR, Postle AD.

Methods Enzymol. 2007;432:233-46.

PMID:
17954220
41.

Developmental changes in rat surfactant lipidomics in the context of species variability.

Bernhard W, Schmiedl A, Koster G, Orgeig S, Acevedo C, Poets CF, Postle AD.

Pediatr Pulmonol. 2007 Sep;42(9):794-804.

PMID:
17659602
42.

Probing phospholipid dynamics by electrospray ionisation mass spectrometry.

Postle AD, Wilton DC, Hunt AN, Attard GS.

Prog Lipid Res. 2007 May-Jul;46(3-4):200-24. Epub 2007 Apr 24. Review.

PMID:
17540449
43.

Cortisol clearance and associations with insulin sensitivity, body fat and fatty liver in middle-aged men.

Holt HB, Wild SH, Postle AD, Zhang J, Koster G, Umpleby M, Shojaee-Moradie F, Dewbury K, Wood PJ, Phillips DI, Byrne CD.

Diabetologia. 2007 May;50(5):1024-32. Epub 2007 Mar 17.

PMID:
17370058
44.

Mass spectrometry determination of endonuclear phospholipid composition and dynamics.

Hunt AN, Postle AD.

Methods. 2006 Jun;39(2):104-11. Review.

PMID:
16831558
45.

Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gamma delta T cells.

Russano AM, Agea E, Corazzi L, Postle AD, De Libero G, Porcelli S, de Benedictis FM, Spinozzi F.

J Allergy Clin Immunol. 2006 May;117(5):1178-84. Epub 2006 Feb 21.

PMID:
16675349
46.

In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development.

Goto M, Piper Hanley K, Marcos J, Wood PJ, Wright S, Postle AD, Cameron IT, Mason JI, Wilson DI, Hanley NA.

J Clin Invest. 2006 Apr;116(4):953-60.

47.

Lipidomics of cellular and secreted phospholipids from differentiated human fetal type II alveolar epithelial cells.

Postle AD, Gonzales LW, Bernhard W, Clark GT, Godinez MH, Godinez RI, Ballard PL.

J Lipid Res. 2006 Jun;47(6):1322-31. Epub 2006 Mar 2.

48.

Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures.

Rigoni M, Caccin P, Gschmeissner S, Koster G, Postle AD, Rossetto O, Schiavo G, Montecucco C.

Science. 2005 Dec 9;310(5754):1678-80.

49.

The composition of pulmonary surfactant from diving mammals.

Miller NJ, Postle AD, Orgeig S, Koster G, Daniels CB.

Respir Physiol Neurobiol. 2006 Jun;152(2):152-68. Epub 2005 Sep 1.

PMID:
16140043
50.

Dipalmitoylphosphatidylcholine is not the major surfactant phospholipid species in all mammals.

Lang CJ, Postle AD, Orgeig S, Possmayer F, Bernhard W, Panda AK, Jürgens KD, Milsom WK, Nag K, Daniels CB.

Am J Physiol Regul Integr Comp Physiol. 2005 Nov;289(5):R1426-39. Epub 2005 Jul 21.

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