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Items: 1 to 50 of 56

1.

Sugar and ice: Immunoelectron microscopy using cryosections according to the Tokuyasu method.

Möbius W, Posthuma G.

Tissue Cell. 2019 Apr;57:90-102. doi: 10.1016/j.tice.2018.08.010. Epub 2018 Sep 3. Review.

PMID:
30201442
2.

Identification of FAM173B as a protein methyltransferase promoting chronic pain.

Willemen HLDM, Kavelaars A, Prado J, Maas M, Versteeg S, Nellissen LJJ, Tromp J, Gonzalez Cano R, Zhou W, Jakobsson ME, Małecki J, Posthuma G, Habib AM, Heijnen CJ, Falnes PØ, Eijkelkamp N.

PLoS Biol. 2018 Feb 14;16(2):e2003452. doi: 10.1371/journal.pbio.2003452. eCollection 2018 Feb.

3.

Imaging the Antistaphylococcal Activity of CATH-2: Mechanism of Attack and Regulation of Inflammatory Response.

Schneider VAF, Coorens M, Tjeerdsma-van Bokhoven JLM, Posthuma G, van Dijk A, Veldhuizen EJA, Haagsman HP.

mSphere. 2017 Nov 1;2(6). pii: e00370-17. doi: 10.1128/mSphere.00370-17. eCollection 2017 Nov-Dec.

4.

Toll-like Receptor 2 Signalling and the Lysosomal Machinery in Barrett's Esophagus.

Verbeek RE, Siersema PD, Vleggaar FP, Ten Kate FJ, Posthuma G, Souza RF, de Haan J, van Baal JW.

J Gastrointestin Liver Dis. 2016 Sep;25(3):273-82. doi: 10.15403/jgld.2014.1121.253.rc2.

5.

Imaging the antimicrobial mechanism(s) of cathelicidin-2.

Schneider VA, Coorens M, Ordonez SR, Tjeerdsma-van Bokhoven JL, Posthuma G, van Dijk A, Haagsman HP, Veldhuizen EJ.

Sci Rep. 2016 Sep 14;6:32948. doi: 10.1038/srep32948.

6.

ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization.

Bruurs LJ, Donker L, Zwakenberg S, Zwartkruis FJ, Begthel H, Knisely AS, Posthuma G, van de Graaf SF, Paulusma CC, Bos JL.

J Cell Biol. 2015 Sep 28;210(7):1055-63. doi: 10.1083/jcb.201505118.

7.

pH-controlled aggregation polymorphism of amyloidogenic Aβ(16-22): insights for obtaining peptide tapes and peptide nanotubes, as function of the N-terminal capping moiety.

Elgersma RC, Kroon-Batenburg LM, Posthuma G, Meeldijk JD, Rijkers DT, Liskamp RM.

Eur J Med Chem. 2014 Dec 17;88:55-65. doi: 10.1016/j.ejmech.2014.07.089. Epub 2014 Jul 25.

PMID:
25087966
8.

Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling.

Wilson CW, Parker LH, Hall CJ, Smyczek T, Mak J, Crow A, Posthuma G, De Mazière A, Sagolla M, Chalouni C, Vitorino P, Roose-Girma M, Warming S, Klumperman J, Crosier PS, Ye W.

Blood. 2013 Nov 21;122(22):3678-90. doi: 10.1182/blood-2013-02-483156. Epub 2013 Jul 25.

9.

Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes.

de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW.

J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18396. eCollection 2012.

10.

The platelet interior revisited: electron tomography reveals tubular alpha-granule subtypes.

van Nispen tot Pannerden H, de Haas F, Geerts W, Posthuma G, van Dijk S, Heijnen HF.

Blood. 2010 Aug 19;116(7):1147-56. doi: 10.1182/blood-2010-02-268680. Epub 2010 May 3.

PMID:
20439620
11.

Backbone-modified amylin derivatives: implications for amyloid inhibitor design and as template for self-assembling bionanomaterials.

Elgersma RC, Posthuma G, Rijkers DT, Liskamp RM.

J Pept Sci. 2007 Nov;13(11):709-16. Review.

PMID:
17890652
12.

Five genes encoding surface-exposed LPXTG proteins are enriched in hospital-adapted Enterococcus faecium clonal complex 17 isolates.

Hendrickx AP, van Wamel WJ, Posthuma G, Bonten MJ, Willems RJ.

J Bacteriol. 2007 Nov;189(22):8321-32. Epub 2007 Sep 14.

13.

Immunogold labeling of cryosections from high-pressure frozen cells.

van Donselaar E, Posthuma G, Zeuschner D, Humbel BM, Slot JW.

Traffic. 2007 May;8(5):471-85.

14.

Transformation of the amyloidogenic peptide amylin(20-29) into its corresponding peptoid and retropeptoid: access to both an amyloid inhibitor and template for self-assembled supramolecular tapes.

Elgersma RC, Mulder GE, Kruijtzer JA, Posthuma G, Rijkers DT, Liskamp RM.

Bioorg Med Chem Lett. 2007 Apr 1;17(7):1837-42. Epub 2007 Jan 24.

PMID:
17276062
15.

Growth condition-dependent Esp expression by Enterococcus faecium affects initial adherence and biofilm formation.

Van Wamel WJ, Hendrickx AP, Bonten MJ, Top J, Posthuma G, Willems RJ.

Infect Immun. 2007 Feb;75(2):924-31. Epub 2006 Nov 21.

16.
17.

Self-assembly of amylin(20-29) amide-bond derivatives into helical ribbons and peptide nanotubes rather than fibrils.

Elgersma RC, Meijneke T, Posthuma G, Rijkers DT, Liskamp RM.

Chemistry. 2006 May 3;12(14):3714-25.

PMID:
16528792
18.

Beta-amyloid (Abeta) causes detachment of N1E-115 neuroblastoma cells by acting as a scaffold for cell-associated plasminogen activation.

Kranenburg O, Bouma B, Gent YY, Aarsman CJ, Kayed R, Posthuma G, Schiks B, Voest EE, Gebbink MF.

Mol Cell Neurosci. 2005 Mar;28(3):496-508.

PMID:
15737740
19.

Quantification of synapse formation and maintenance in vivo in the absence of synaptic release.

Bouwman J, Maia AS, Camoletto PG, Posthuma G, Roubos EW, Oorschot VM, Klumperman J, Verhage M.

Neuroscience. 2004;126(1):115-26.

PMID:
15145078
20.

Endosomal compartmentalization in three dimensions: implications for membrane fusion.

Murk JL, Humbel BM, Ziese U, Griffith JM, Posthuma G, Slot JW, Koster AJ, Verkleij AJ, Geuze HJ, Kleijmeer MJ.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13332-7. Epub 2003 Nov 3.

21.

Age-related changes in the ultrastructure of the resting follicle pool in human ovaries.

de Bruin JP, Dorland M, Spek ER, Posthuma G, van Haaften M, Looman CW, te Velde ER.

Biol Reprod. 2004 Feb;70(2):419-24. Epub 2003 Oct 15.

PMID:
14561658
22.

Influence of aldehyde fixation on the morphology of endosomes and lysosomes: quantitative analysis and electron tomography.

Murk JL, Posthuma G, Koster AJ, Geuze HJ, Verkleij AJ, Kleijmeer MJ, Humbel BM.

J Microsc. 2003 Oct;212(Pt 1):81-90.

23.

Glycation induces formation of amyloid cross-beta structure in albumin.

Bouma B, Kroon-Batenburg LM, Wu YP, Brünjes B, Posthuma G, Kranenburg O, de Groot PG, Voest EE, Gebbink MF.

J Biol Chem. 2003 Oct 24;278(43):41810-9. Epub 2003 Aug 8.

24.

The transmembrane domain of surfactant protein C precursor determines the morphology of the induced membrane compartment in CHO cells.

ten Brinke A, Posthuma G, Batenburg JJ, Haagsman HP, Ridder AN, van Golde LM, Vaandrager AB.

Eur J Cell Biol. 2003 Jun;82(6):285-94.

PMID:
12868596
25.

Proliferation and differentiation of bovine type A spermatogonia during long-term culture.

Izadyar F, Den Ouden K, Creemers LB, Posthuma G, Parvinen M, De Rooij DG.

Biol Reprod. 2003 Jan;68(1):272-81.

PMID:
12493723
26.

Inhibition of amyloid fibril formation of human amylin by N-alkylated amino acid and alpha-hydroxy acid residue containing peptides.

Rijkers DT, Höppener JW, Posthuma G, Lips CJ, Liskamp RM.

Chemistry. 2002 Sep 16;8(18):4285-91.

PMID:
12298020
27.

Ultrastructure of the resting ovarian follicle pool in healthy young women.

de Bruin JP, Dorland M, Spek ER, Posthuma G, van Haaften M, Looman CW, te Velde ER.

Biol Reprod. 2002 Apr;66(4):1151-60.

PMID:
11906936
28.

The ER to Golgi interface is the major concentration site of secretory proteins in the exocrine pancreatic cell.

Oprins A, Rabouille C, Posthuma G, Klumperman J, Geuze HJ, Slot JW.

Traffic. 2001 Nov;2(11):831-8.

29.

A reliable and convenient method to store ultrathin thawed cryosections prior to immunolabeling.

Griffith JM, Posthuma G.

J Histochem Cytochem. 2002 Jan;50(1):57-62.

PMID:
11748294
30.

Synthetic peptides derived from the beta2-beta3 loop of Raphanus sativus antifungal protein 2 that mimic the active site.

Schaaper WM, Posthuma GA, Plasman HH, Sijtsma L, Fant F, Borremans FA, Thevissen K, Broekaert WF, Meloen RH, van Amerongen A.

J Pept Res. 2001 May;57(5):409-18.

PMID:
11350601
31.

Immunoelectron microscopy of antigen processing in dendritic cells.

Kleijmeer MJ, Posthuma G, Geuze HJ.

Methods Mol Med. 2001;64:387-411. doi: 10.1385/1-59259-150-7:387.

PMID:
21374277
32.

Subcellular distribution of CFTR in rat intestine supports a physiologic role for CFTR regulation by vesicle traffic.

Ameen NA, van Donselaar E, Posthuma G, de Jonge H, McLaughlin G, Geuze HJ, Marino C, Peters PJ.

Histochem Cell Biol. 2000 Sep;114(3):219-28.

PMID:
11083465
33.

Lysozyme distribution and conformation in a biodegradable polymer matrix as determined by FTIR techniques.

van de Weert M, van 't Hof1 R, van der Weerd J, Heeren RM, Posthuma G, Hennink WE, Crommelin DJ.

J Control Release. 2000 Jul 31;68(1):31-40.

PMID:
10884577
34.

Effects of physicochemical characteristics of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes on cellular association and internalization.

Zuidam NJ, Posthuma G, de Vries ET, Crommelin DJ, Hennink WE, Storm G.

J Drug Target. 2000;8(1):51-66.

PMID:
10761645
35.

Resistance to both complement activation and phagocytosis in type 3 pneumococci is mediated by the binding of complement regulatory protein factor H.

Neeleman C, Geelen SP, Aerts PC, Daha MR, Mollnes TE, Roord JJ, Posthuma G, van Dijk H, Fleer A.

Infect Immun. 1999 Sep;67(9):4517-24.

36.

Moraxella (Branhamella) catarrhalis BRO beta-lactamase: a lipoprotein of gram-positive origin?

Bootsma HJ, Aerts PC, Posthuma G, Harmsen T, Verhoef J, van Dijk H, Mooi FR.

J Bacteriol. 1999 Aug;181(16):5090-3.

37.

Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model.

Höppener JW, Oosterwijk C, Nieuwenhuis MG, Posthuma G, Thijssen JH, Vroom TM, Ahrén B, Lips CJ.

Diabetologia. 1999 Apr;42(4):427-34.

PMID:
10230646
38.

Intestinal carbamoyl phosphate synthase I in human and rat. Expression during development shows species differences and mosaic expression in duodenum of both species.

Van Beers EH, Rings EH, Posthuma G, Dingemanse MA, Taminiau JA, Heymans HS, Einerhand AW, Büller HA, Dekker J.

J Histochem Cytochem. 1998 Feb;46(2):231-40.

PMID:
9446830
39.

Site- and cell-specific alteration of lung copper/zinc and manganese superoxide dismutases by chronic ozone exposure.

Weller BL, Crapo JD, Slot J, Posthuma G, Plopper CG, Pinkerton KE.

Am J Respir Cell Mol Biol. 1997 Nov;17(5):552-60.

PMID:
9374106
40.

Glucose transporter (GLUT-4) is targeted to secretory granules in rat atrial cardiomyocytes.

Slot JW, Garruti G, Martin S, Oorschot V, Posthuma G, Kraegen EW, Laybutt R, Thibault G, James DE.

J Cell Biol. 1997 Jun 16;137(6):1243-54.

41.

Antifungal activity of synthetic 15-mer peptides based on the Rs-AFP2 (Raphanus sativus antifungal protein 2) sequence.

De Samblanx GW, Fernandez del Carmen A, Sijtsma L, Plasman HH, Schaaper WM, Posthuma GA, Fant F, Meloen RH, Broekaert WF, van Amerongen A.

Pept Res. 1996 Nov-Dec;9(6):262-8.

PMID:
9048418
42.

Interventional thermal injury of the arterial wall: unfolding of von Willebrand factor and its increased binding to collagen after 55 degrees C heating.

Post MJ, de Graaf-Bos AN, Posthuma G, de Groot PG, Sixma JJ, Borst C.

Thromb Haemost. 1996 Mar;75(3):515-9.

PMID:
8701418
43.

Endocytosis of GPI-linked membrane folate receptor-alpha.

Rijnboutt S, Jansen G, Posthuma G, Hynes JB, Schornagel JH, Strous GJ.

J Cell Biol. 1996 Jan;132(1-2):35-47.

44.

Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide.

de Koning EJ, Morris ER, Hofhuis FM, Posthuma G, Höppener JW, Morris JF, Capel PJ, Clark A, Verbeek JS.

Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8467-71.

45.

Detergent insolubility of alkaline phosphatase during biosynthetic transport and endocytosis. Role of cholesterol.

Cerneus DP, Ueffing E, Posthuma G, Strous GJ, van der Ende A.

J Biol Chem. 1993 Feb 15;268(5):3150-5.

46.

Detergent-insolubility during the biosynthesis of membrane folate receptor-2.

Rijnboutt S, Strous G, Bijleveld E, Posthuma G, Ratnam M, Schornagel J, Jansen G.

Adv Exp Med Biol. 1993;338:761-5. No abstract available.

PMID:
8304224
47.

Immunogold determination of Plasmodium falciparum circumsporozoite protein in Anopheles stephensi salivary gland cells.

Posthuma G, Meis JF, Verhave JP, Gigengack S, Hollingdale MR, Ponnudurai T, Geuze HJ.

Eur J Cell Biol. 1989 Jun;49(1):66-72.

PMID:
2668001
48.

Quantitative aspects of immunogold labeling in embedded and in nonembedded sections.

Slot JW, Posthuma G, Chang LY, Crapo JD, Geuze HJ.

Am J Anat. 1989 Jun-Jul;185(2-3):271-81.

PMID:
2476022
49.

Immunogold determination of amylase concentrations in pancreatic subcellular compartments.

Posthuma G, Slot JW, Veenendaal T, Geuze HJ.

Eur J Cell Biol. 1988 Jun;46(2):327-35.

PMID:
2458929
50.

Immunogold localization of circumsporozoite protein of the malaria parasite Plasmodium falciparum during sporogony in Anopheles stephensi midguts.

Posthuma G, Meis JF, Verhave JP, Hollingdale MR, Ponnudurai T, Meuwissen JH, Geuze HJ.

Eur J Cell Biol. 1988 Apr;46(1):18-24.

PMID:
3294006

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