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Off-site versus on-site clinical microbiology laboratory: a 2-year comparison study of blood culture result reporting.

Posteraro P, Gasparoli C, Errico FM, Massaria G, Sanguinetti M, Posteraro B.

Clin Microbiol Infect. 2019 Jun 22. pii: S1198-743X(19)30366-0. doi: 10.1016/j.cmi.2019.06.021. [Epub ahead of print] No abstract available.


Diagnosis and treatment of invasive fungal infections: looking ahead.

Sanguinetti M, Posteraro B, Beigelman-Aubry C, Lamoth F, Dunet V, Slavin M, Richardson MD.

J Antimicrob Chemother. 2019 Mar 1;74(Supplement_2):ii27-ii37. doi: 10.1093/jac/dkz041.


Direct use of eazyplex® SuperBug CRE assay from positive blood cultures in conjunction with inpatient infectious disease consulting for timely appropriate antimicrobial therapy in Escherichia coli and Klebsiella pneumoniae bloodstream infections.

Fiori B, D'Inzeo T, Posteraro B, Menchinelli G, Liotti FM, De Angelis G, De Maio F, Fantoni M, Murri R, Scoppettuolo G, Ventura G, Tumbarello M, Pennestrì F, Taccari F, Sanguinetti M, Spanu T.

Infect Drug Resist. 2019 May 3;12:1055-1062. doi: 10.2147/IDR.S206323. eCollection 2019.


Efficient Inactivation of Clinically Relevant Antimicrobial Drug Concentrations by BacT/Alert or Bactec Resin-Containing Media in Simulated Adult Blood Cultures.

Menchinelli G, Liotti FM, Giordano L, De Angelis G, Sanguinetti M, Spanu T, Posteraro B.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00420-19. doi: 10.1128/AAC.00420-19. Print 2019 Jul.


Simplified Testing Method for Direct Detection of Carbapenemase-Producing Organisms from Positive Blood Cultures Using the NG-Test Carba 5 Assay.

Giordano L, Fiori B, D'Inzeo T, Parisi G, Liotti FM, Menchinelli G, De Angelis G, De Maio F, Luzzaro F, Sanguinetti M, Posteraro B, Spanu T.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00550-19. doi: 10.1128/AAC.00550-19. Print 2019 Jul.


In Vitro Activity of Fenticonazole against Candida and Bacterial Vaginitis Isolates Determined by Mono- or Dual-Species Testing Assays.

Sanguinetti M, Cantón E, Torelli R, Tumietto F, Espinel-Ingroff A, Posteraro B.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e02693-18. doi: 10.1128/AAC.02693-18. Print 2019 Jul.


Comparable Serum and Plasma 1,3-β-d-Glucan Values Obtained Using the Wako β-Glucan Test in Patients with Probable or Proven Fungal Diseases.

De Carolis E, Marchionni F, Torelli R, Posteraro P, De Pascale G, Carelli S, Sanguinetti M, Posteraro B.

J Clin Microbiol. 2019 Apr 26;57(5). pii: e00149-19. doi: 10.1128/JCM.00149-19. Print 2019 May. No abstract available.


In vitro Evaluation of BACT/ALERT® VIRTUO®, BACT/ALERT 3D®, and BACTEC™ FX Automated Blood Culture Systems for Detection of Microbial Pathogens Using Simulated Human Blood Samples.

Menchinelli G, Liotti FM, Fiori B, De Angelis G, D'Inzeo T, Giordano L, Posteraro B, Sabatucci M, Sanguinetti M, Spanu T.

Front Microbiol. 2019 Feb 19;10:221. doi: 10.3389/fmicb.2019.00221. eCollection 2019.


Clostridium difficile: trend in an Italian Tertiary Care Hospital during fifteen years, 2002-2016.

Masucci L, Nicolotti N, Graffeo R, Tamburrano A, Archibusacci CM, Nagel D, Quaranta G, Eisendle K, Primus S, Romano L, Mazzella P, Posteraro B, Cammarota G, Sanguinetti M.

Minerva Med. 2019 Apr;110(2):168-171. doi: 10.23736/S0026-4806.18.05740-3. No abstract available.


[Hygienic safety of infant milk powder formulas in hospital setting].

Quaranta G, Posteraro B, Cambieri A, Berloco F, Vincenti S, Turnaturi C, Laurenti P.

Ig Sanita Pubbl. 2018 Sep-Oct;74(5):433-442. Italian.


Antimicrobial susceptibility testing of pathogens isolated from blood culture: a performance comparison of Accelerate Pheno™ and VITEK® 2 systems with the broth microdilution method.

De Angelis G, Posteraro B, Menchinelli G, Liotti FM, Spanu T, Sanguinetti M.

J Antimicrob Chemother. 2019 Jan 1;74(Supplement_1):i24-i31. doi: 10.1093/jac/dky532.


Performance evaluation of the (1,3)-β-D-glucan detection assay in non-intensive care unit adult patients.

Murri R, Camici M, Posteraro B, Giovannenze F, Taccari F, Ventura G, Scoppettuolo G, Sanguinetti M, Cauda R, Fantoni M.

Infect Drug Resist. 2018 Dec 20;12:19-24. doi: 10.2147/IDR.S181489. eCollection 2019.


Desirability of outcome ranking (DOOR) for comparing diagnostic tools and early therapeutic choices in patients with suspected candidemia.

Giacobbe DR, Signori A, Tumbarello M, Ungaro R, Sarteschi G, Furfaro E, Mikulska M, Sanguinetti M, Posteraro B, Losito AR, De Pascale G, Del Bono V, Viscoli C.

Eur J Clin Microbiol Infect Dis. 2019 Feb;38(2):413-417. doi: 10.1007/s10096-018-3441-1. Epub 2018 Nov 30.


MicroRNAs expression profiles as diagnostic biomarkers of gastric cancer: a systematic literature review.

Stojanovic J, Tognetto A, Tiziano DF, Leoncini E, Posteraro B, Pastorino R, Boccia S.

Biomarkers. 2019 Mar;24(2):110-119. doi: 10.1080/1354750X.2018.1539765. Epub 2018 Nov 15.


Liver Injury, Endotoxemia, and Their Relationship to Intestinal Microbiota Composition in Alcohol-Preferring Rats.

Posteraro B, Paroni Sterbini F, Petito V, Rocca S, Cubeddu T, Graziani C, Arena V, Vassallo GA, Mosoni C, Lopetuso L, Lorrai I, Maccioni P, Masucci L, Martini C, Gasbarrini A, Sanguinetti M, Colombo G, Addolorato G.

Alcohol Clin Exp Res. 2018 Dec;42(12):2313-2325. doi: 10.1111/acer.13900. Epub 2018 Oct 29.


Susceptibility Testing of Fungi to Antifungal Drugs.

Sanguinetti M, Posteraro B.

J Fungi (Basel). 2018 Sep 15;4(3). pii: E110. doi: 10.3390/jof4030110. Review.


Fatal fulminant cryptococcemia complicating sarcoidosis: Is it to be expected?

Posteraro P, Vacca K, Celi M, De Angelis G, Vella A, Sanguinetti M, Posteraro B.

Med Mycol Case Rep. 2018 Aug 16;22:42-44. doi: 10.1016/j.mmcr.2018.08.006. eCollection 2018 Dec.


Expression profiling in a mammalian host reveals the strong induction of genes encoding LysM domain-containing proteins in Enterococcus faecium.

Cacaci M, Giraud C, Leger L, Torelli R, Martini C, Posteraro B, Palmieri V, Sanguinetti M, Bugli F, Hartke A.

Sci Rep. 2018 Aug 17;8(1):12412. doi: 10.1038/s41598-018-30882-z.


Incidence and antimicrobial resistance trends in bloodstream infections caused by ESKAPE and Escherichia coli at a large teaching hospital in Rome, a 9-year analysis (2007-2015).

De Angelis G, Fiori B, Menchinelli G, D'Inzeo T, Liotti FM, Morandotti GA, Sanguinetti M, Posteraro B, Spanu T.

Eur J Clin Microbiol Infect Dis. 2018 Sep;37(9):1627-1636. doi: 10.1007/s10096-018-3292-9. Epub 2018 Jun 9.


CoERG11 A395T mutation confers azole resistance in Candida orthopsilosis clinical isolates.

Rizzato C, Poma N, Zoppo M, Posteraro B, Mello E, Bottai D, Lupetti A, Sanguinetti M, Tavanti A.

J Antimicrob Chemother. 2018 Jul 1;73(7):1815-1822. doi: 10.1093/jac/dky122.


T2Bacteria magnetic resonance assay for the rapid detection of ESKAPEc pathogens directly in whole blood.

De Angelis G, Posteraro B, De Carolis E, Menchinelli G, Franceschi F, Tumbarello M, De Pascale G, Spanu T, Sanguinetti M.

J Antimicrob Chemother. 2018 Mar 1;73(suppl_4):iv20-iv26. doi: 10.1093/jac/dky049.


[Hygienic suitability of food and food-contact surfaces in a hospital canteen: the experience of a University Hospital in Italy].

Quaranta G, Marruco R, Posteraro B, Cambieri A, Berloco F, Sezzatini R, Boninti F, Turnaturi C, Laurenti P.

Ig Sanita Pubbl. 2017 Nov-Dec;73(6):579-593. Italian.


Actoxumab + bezlotoxumab combination: what promise for Clostridium difficile treatment?

Posteraro B, Pea F, Masucci L, Posteraro P, Sanguinetti M.

Expert Opin Biol Ther. 2018 Apr;18(4):469-476. doi: 10.1080/14712598.2018.1452908. Epub 2018 Mar 15. Review.


Microbiologic and clinical characteristics of biofilm-forming Candida parapsilosis isolates associated with fungaemia and their impact on mortality.

Soldini S, Posteraro B, Vella A, De Carolis E, Borghi E, Falleni M, Losito AR, Maiuro G, Trecarichi EM, Sanguinetti M, Tumbarello M.

Clin Microbiol Infect. 2018 Jul;24(7):771-777. doi: 10.1016/j.cmi.2017.11.005. Epub 2017 Nov 10.


A rapid diagnostic workflow for cefotaxime-resistant Escherichia coli and Klebsiella pneumoniae detection from blood cultures by MALDI-TOF mass spectrometry.

De Carolis E, Paoletti S, Nagel D, Vella A, Mello E, Palucci I, De Angelis G, D'Inzeo T, Sanguinetti M, Posteraro B, Spanu T.

PLoS One. 2017 Oct 5;12(10):e0185935. doi: 10.1371/journal.pone.0185935. eCollection 2017.


Importance of Resolving Fungal Nomenclature: the Case of Multiple Pathogenic Species in the Cryptococcus Genus.

Hagen F, Lumbsch HT, Arsic Arsenijevic V, Badali H, Bertout S, Billmyre RB, Bragulat MR, Cabañes FJ, Carbia M, Chakrabarti A, Chaturvedi S, Chaturvedi V, Chen M, Chowdhary A, Colom MF, Cornely OA, Crous PW, Cuétara MS, Diaz MR, Espinel-Ingroff A, Fakhim H, Falk R, Fang W, Herkert PF, Ferrer Rodríguez C, Fraser JA, Gené J, Guarro J, Idnurm A, Illnait-Zaragozi MT, Khan Z, Khayhan K, Kolecka A, Kurtzman CP, Lagrou K, Liao W, Linares C, Meis JF, Nielsen K, Nyazika TK, Pan W, Pekmezovic M, Polacheck I, Posteraro B, de Queiroz Telles F Filho, Romeo O, Sánchez M, Sampaio A, Sanguinetti M, Sriburee P, Sugita T, Taj-Aldeen SJ, Takashima M, Taylor JW, Theelen B, Tomazin R, Verweij PE, Wahyuningsih R, Wang P, Boekhout T.

mSphere. 2017 Aug 30;2(4). pii: e00238-17. doi: 10.1128/mSphere.00238-17. eCollection 2017 Jul-Aug.


Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata.

Vella A, De Carolis E, Mello E, Perlin DS, Sanglard D, Sanguinetti M, Posteraro B.

Sci Rep. 2017 Aug 22;7(1):9099. doi: 10.1038/s41598-017-09329-4.


Different effects of matrix degrading enzymes towards biofilms formed by E. faecalis and E. faecium clinical isolates.

Torelli R, Cacaci M, Papi M, Paroni Sterbini F, Martini C, Posteraro B, Palmieri V, De Spirito M, Sanguinetti M, Bugli F.

Colloids Surf B Biointerfaces. 2017 Oct 1;158:349-355. doi: 10.1016/j.colsurfb.2017.07.010. Epub 2017 Jul 9.


The synthetic killer peptide KP impairs Candida albicans biofilm in vitro.

Paulone S, Ardizzoni A, Tavanti A, Piccinelli S, Rizzato C, Lupetti A, Colombari B, Pericolini E, Polonelli L, Magliani W, Conti S, Posteraro B, Cermelli C, Blasi E, Peppoloni S.

PLoS One. 2017 Jul 13;12(7):e0181278. doi: 10.1371/journal.pone.0181278. eCollection 2017.


Combined use of serum (1,3)-β-D-glucan and procalcitonin for the early differential diagnosis between candidaemia and bacteraemia in intensive care units.

Giacobbe DR, Mikulska M, Tumbarello M, Furfaro E, Spadaro M, Losito AR, Mesini A, De Pascale G, Marchese A, Bruzzone M, Pelosi P, Mussap M, Molin A, Antonelli M, Posteraro B, Sanguinetti M, Viscoli C, Del Bono V; ISGRI-SITA (Italian Study Group on Resistant Infections of the Società Italiana Terapia Antinfettiva).

Crit Care. 2017 Jul 10;21(1):176. doi: 10.1186/s13054-017-1763-5.


The Enterococcus faecalis virulence factor ElrA interacts with the human Four-and-a-Half LIM Domains Protein 2.

Jamet A, Dervyn R, Lapaque N, Bugli F, Perez-Cortez NG, Blottière HM, Twizere JC, Sanguinetti M, Posteraro B, Serror P, Maguin E.

Sci Rep. 2017 Jul 4;7(1):4581. doi: 10.1038/s41598-017-04875-3.


Antibodies against a β-glucan-protein complex of Candida albicans and its potential as indicator of protective immunity in candidemic patients.

Torosantucci A, Tumbarello M, Bromuro C, Chiani P, Posteraro B, Sanguinetti M, Cauda R, Cassone A.

Sci Rep. 2017 Jun 2;7(1):2722. doi: 10.1038/s41598-017-02977-6.


Susceptibility Testing of Common and Uncommon Aspergillus Species against Posaconazole and Other Mold-Active Antifungal Azoles Using the Sensititre Method.

Mello E, Posteraro B, Vella A, De Carolis E, Torelli R, D'Inzeo T, Verweij PE, Sanguinetti M.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e00168-17. doi: 10.1128/AAC.00168-17. Print 2017 Jun.


New approaches for antifungal susceptibility testing.

Sanguinetti M, Posteraro B.

Clin Microbiol Infect. 2017 Dec;23(12):931-934. doi: 10.1016/j.cmi.2017.03.025. Epub 2017 Apr 1. Review.


Predictors of failure after single faecal microbiota transplantation in patients with recurrent Clostridium difficile infection: results from a 3-year, single-centre cohort study.

Ianiro G, Valerio L, Masucci L, Pecere S, Bibbò S, Quaranta G, Posteraro B, Currò D, Sanguinetti M, Gasbarrini A, Cammarota G.

Clin Microbiol Infect. 2017 May;23(5):337.e1-337.e3. doi: 10.1016/j.cmi.2016.12.025. Epub 2017 Jan 3.


Molecular Detection of Resistance to Azole Components.

Posteraro B, Vella A, De Carolis E, Sanguinetti M.

Methods Mol Biol. 2017;1508:423-435.


Molecular Detection of Resistance to Echinocandins.

Posteraro B, Vella A, De Carolis E, Sanguinetti M.

Methods Mol Biol. 2017;1508:413-421.


Identification of Molds by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry.

Sanguinetti M, Posteraro B.

J Clin Microbiol. 2017 Feb;55(2):369-379. doi: 10.1128/JCM.01640-16. Epub 2016 Nov 2. Review.


Effects of Proton Pump Inhibitors on the Gastric Mucosa-Associated Microbiota in Dyspeptic Patients.

Paroni Sterbini F, Palladini A, Masucci L, Cannistraci CV, Pastorino R, Ianiro G, Bugli F, Martini C, Ricciardi W, Gasbarrini A, Sanguinetti M, Cammarota G, Posteraro B.

Appl Environ Microbiol. 2016 Oct 27;82(22):6633-6644. Print 2016 Nov 15.


Mass spectrometry applications in microbiology beyond microbe identification: progress and potential.

Sanguinetti M, Posteraro B.

Expert Rev Proteomics. 2016 Oct;13(10):965-977. doi: 10.1080/14789450.2016.1231578. Epub 2016 Sep 14.


Serum Endotoxin Activity Measured with Endotoxin Activity Assay Is Associated with Serum Interleukin-6 Levels in Patients on Chronic Hemodialysis.

Bossola M, Di Stasio E, Sanguinetti M, Posteraro B, Antocicco M, Pepe G, Mello E, Bugli F, Vulpio C.

Blood Purif. 2016;42(4):294-300. Epub 2016 Aug 31.


In vitro effect of clarithromycin and alginate lyase against helicobacter pylori biofilm.

Bugli F, Palmieri V, Torelli R, Papi M, De Spirito M, Cacaci M, Galgano S, Masucci L, Paroni Sterbini F, Vella A, Graffeo R, Posteraro B, Sanguinetti M.

Biotechnol Prog. 2016 Nov;32(6):1584-1591. doi: 10.1002/btpr.2339. Epub 2016 Sep 8.


Upregulation of the Adhesin Gene EPA1 Mediated by PDR1 in Candida glabrata Leads to Enhanced Host Colonization.

Vale-Silva LA, Moeckli B, Torelli R, Posteraro B, Sanguinetti M, Sanglard D.

mSphere. 2016 Mar 2;1(2). pii: e00065-15. doi: 10.1128/mSphere.00065-15. eCollection 2016 Mar-Apr.


Diagnostic of Fungal Infections Related to Biofilms.

Sanguinetti M, Posteraro B.

Adv Exp Med Biol. 2016;931:63-82. doi: 10.1007/5584_2016_9. Review.


Management of candidemia in patients with Clostridium difficile infection.

Falcone M, Venditti M, Sanguinetti M, Posteraro B.

Expert Rev Anti Infect Ther. 2016 Jul;14(7):679-85. doi: 10.1080/14787210.2016.1197118. Review.


(1,3)-β-d-Glucan-based antifungal treatment in critically ill adults at high risk of candidaemia: an observational study.

Posteraro B, Tumbarello M, De Pascale G, Liberto E, Vallecoccia MS, De Carolis E, Di Gravio V, Trecarichi EM, Sanguinetti M, Antonelli M.

J Antimicrob Chemother. 2016 Aug;71(8):2262-9. doi: 10.1093/jac/dkw112. Epub 2016 Apr 28.


Biological Characterization and in Vivo Assessment of the Activity of a New Synthetic Macrocyclic Antifungal Compound.

Deodato D, Maccari G, De Luca F, Sanfilippo S, Casian A, Martini R, D'Arezzo S, Bonchi C, Bugli F, Posteraro B, Vandeputte P, Sanglard D, Docquier JD, Sanguinetti M, Visca P, Botta M.

J Med Chem. 2016 Apr 28;59(8):3854-66. doi: 10.1021/acs.jmedchem.6b00018. Epub 2016 Apr 19.


Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.

Nishikawa JL, Boeszoermenyi A, Vale-Silva LA, Torelli R, Posteraro B, Sohn YJ, Ji F, Gelev V, Sanglard D, Sanguinetti M, Sadreyev RI, Mukherjee G, Bhyravabhotla J, Buhrlage SJ, Gray NS, Wagner G, Näär AM, Arthanari H.

Nature. 2016 Feb 25;530(7591):485-9. doi: 10.1038/nature16963. Epub 2016 Feb 17.


[Comparison of conventional culture methods and quantitative real-time PCR methods for the detection of Legionella pneumophila in water samples in a large University teaching hospital in Rome, Italy].

Boccia S, Laurenti P, Leoncini E, Amore R, Vincenti S, Arzani D, Berloco F, Boninti F, Bruno S, Celani F, Damiani G, Di Giannantonio P, Moscato U, Posteraro B, Sezzatini R, Vecchioni A, Wachocka M, Ricciardi W, Quaranta G, Ficarra MG.

Ig Sanita Pubbl. 2015 Nov-Dec;71(6):569-76. Italian.


Optimized Use of the MALDI BioTyper System and the FilmArray BCID Panel for Direct Identification of Microbial Pathogens from Positive Blood Cultures.

Fiori B, D'Inzeo T, Giaquinto A, Menchinelli G, Liotti FM, de Maio F, De Angelis G, Quaranta G, Nagel D, Tumbarello M, Posteraro B, Sanguinetti M, Spanu T.

J Clin Microbiol. 2016 Mar;54(3):576-84. doi: 10.1128/JCM.02590-15. Epub 2015 Dec 16.

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