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Items: 1 to 50 of 92

1.

Publisher Correction: Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency.

Atlasi Y, Megchelenbrink W, Peng T, Habibi E, Joshi O, Wang SY, Wang C, Logie C, Poser I, Marks H, Stunnenberg HG.

Nat Cell Biol. 2019 May 16. doi: 10.1038/s41556-019-0341-2. [Epub ahead of print]

PMID:
31097792
2.

Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency.

Atlasi Y, Megchelenbrink W, Peng T, Habibi E, Joshi O, Wang SY, Wang C, Logie C, Poser I, Marks H, Stunnenberg HG.

Nat Cell Biol. 2019 May;21(5):568-578. doi: 10.1038/s41556-019-0310-9. Epub 2019 Apr 29. Erratum in: Nat Cell Biol. 2019 May 16;:.

PMID:
31036938
3.

Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells.

Bechmann N, Poser I, Seifert V, Greunke C, Ullrich M, Qin N, Walch A, Peitzsch M, Robledo M, Pacak K, Pietzsch J, Richter S, Eisenhofer G.

Cancers (Basel). 2019 Apr 28;11(5). pii: E594. doi: 10.3390/cancers11050594.

4.

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins.

Wang J, Choi JM, Holehouse AS, Lee HO, Zhang X, Jahnel M, Maharana S, Lemaitre R, Pozniakovsky A, Drechsel D, Poser I, Pappu RV, Alberti S, Hyman AA.

Cell. 2018 Jul 26;174(3):688-699.e16. doi: 10.1016/j.cell.2018.06.006. Epub 2018 Jun 28.

PMID:
29961577
5.

The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion.

Ivanov MP, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, Novatchkova M, Hériché JK, Wutz G, van der Lelij P, Kreidl E, Hutchins JR, Axelsson-Ekker H, Ellenberg J, Hyman AA, Mechtler K, Peters JM.

EMBO J. 2018 Aug 1;37(15). pii: e97150. doi: 10.15252/embj.201797150. Epub 2018 Jun 21.

PMID:
29930102
6.

RNA buffers the phase separation behavior of prion-like RNA binding proteins.

Maharana S, Wang J, Papadopoulos DK, Richter D, Pozniakovsky A, Poser I, Bickle M, Rizk S, Guillén-Boixet J, Franzmann TM, Jahnel M, Marrone L, Chang YT, Sterneckert J, Tomancak P, Hyman AA, Alberti S.

Science. 2018 May 25;360(6391):918-921. doi: 10.1126/science.aar7366. Epub 2018 Apr 12.

7.

Protein Dynamics in Complex DNA Lesions.

Aleksandrov R, Dotchev A, Poser I, Krastev D, Georgiev G, Panova G, Babukov Y, Danovski G, Dyankova T, Hubatsch L, Ivanova A, Atemin A, Nedelcheva-Veleva MN, Hasse S, Sarov M, Buchholz F, Hyman AA, Grill SW, Stoynov SS.

Mol Cell. 2018 Mar 15;69(6):1046-1061.e5. doi: 10.1016/j.molcel.2018.02.016.

8.

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.

Naumann M, Pal A, Goswami A, Lojewski X, Japtok J, Vehlow A, Naujock M, Günther R, Jin M, Stanslowsky N, Reinhardt P, Sterneckert J, Frickenhaus M, Pan-Montojo F, Storkebaum E, Poser I, Freischmidt A, Weishaupt JH, Holzmann K, Troost D, Ludolph AC, Boeckers TM, Liebau S, Petri S, Cordes N, Hyman AA, Wegner F, Grill SW, Weis J, Storch A, Hermann A.

Nat Commun. 2018 Jan 23;9(1):335. doi: 10.1038/s41467-017-02299-1.

9.

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.

Marrone L, Poser I, Casci I, Japtok J, Reinhardt P, Janosch A, Andree C, Lee HO, Moebius C, Koerner E, Reinhardt L, Cicardi ME, Hackmann K, Klink B, Poletti A, Alberti S, Bickle M, Hermann A, Pandey UB, Hyman AA, Sterneckert JL.

Stem Cell Reports. 2018 Feb 13;10(2):375-389. doi: 10.1016/j.stemcr.2017.12.018. Epub 2018 Jan 18.

10.

Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding.

Toyoda Y, Cattin CJ, Stewart MP, Poser I, Theis M, Kurzchalia TV, Buchholz F, Hyman AA, Müller DJ.

Nat Commun. 2017 Nov 2;8(1):1266. doi: 10.1038/s41467-017-01147-6.

11.

Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis.

Mierzwa BE, Chiaruttini N, Redondo-Morata L, von Filseck JM, König J, Larios J, Poser I, Müller-Reichert T, Scheuring S, Roux A, Gerlich DW.

Nat Cell Biol. 2017 Jul;19(7):787-798. doi: 10.1038/ncb3559. Epub 2017 Jun 12.

12.

Cellular differentiation state modulates the mRNA export activity of SR proteins.

Botti V, McNicoll F, Steiner MC, Richter FM, Solovyeva A, Wegener M, Schwich OD, Poser I, Zarnack K, Wittig I, Neugebauer KM, Müller-McNicoll M.

J Cell Biol. 2017 Jul 3;216(7):1993-2009. doi: 10.1083/jcb.201610051. Epub 2017 Jun 7.

13.

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.

Scharaw S, Iskar M, Ori A, Boncompain G, Laketa V, Poser I, Lundberg E, Perez F, Beck M, Bork P, Pepperkok R.

J Cell Biol. 2016 Nov 21;215(4):543-558. Epub 2016 Nov 8.

14.

ZMYND8 Co-localizes with NuRD on Target Genes and Regulates Poly(ADP-Ribose)-Dependent Recruitment of GATAD2A/NuRD to Sites of DNA Damage.

Spruijt CG, Luijsterburg MS, Menafra R, Lindeboom RG, Jansen PW, Edupuganti RR, Baltissen MP, Wiegant WW, Voelker-Albert MC, Matarese F, Mensinga A, Poser I, Vos HR, Stunnenberg HG, van Attikum H, Vermeulen M.

Cell Rep. 2016 Oct 11;17(3):783-798. doi: 10.1016/j.celrep.2016.09.037.

15.

Antibody Validation in Bioimaging Applications Based on Endogenous Expression of Tagged Proteins.

Skogs M, Stadler C, Schutten R, Hjelmare M, Gnann C, Björk L, Poser I, Hyman A, Uhlén M, Lundberg E.

J Proteome Res. 2017 Jan 6;16(1):147-155. doi: 10.1021/acs.jproteome.6b00821. Epub 2016 Oct 26.

PMID:
27723985
16.

A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.

Ganassi M, Mateju D, Bigi I, Mediani L, Poser I, Lee HO, Seguin SJ, Morelli FF, Vinet J, Leo G, Pansarasa O, Cereda C, Poletti A, Alberti S, Carra S.

Mol Cell. 2016 Sep 1;63(5):796-810. doi: 10.1016/j.molcel.2016.07.021. Epub 2016 Aug 25.

17.

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes.

Cuylen S, Blaukopf C, Politi AZ, Müller-Reichert T, Neumann B, Poser I, Ellenberg J, Hyman AA, Gerlich DW.

Nature. 2016 Jul 14;535(7611):308-12. doi: 10.1038/nature18610. Epub 2016 Jun 29.

18.

Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length.

Zheng X, Ramani A, Soni K, Gottardo M, Zheng S, Ming Gooi L, Li W, Feng S, Mariappan A, Wason A, Widlund P, Pozniakovsky A, Poser I, Deng H, Ou G, Riparbelli M, Giuliano C, Hyman AA, Sattler M, Gopalakrishnan J, Li H.

Nat Commun. 2016 Jun 16;7:11874. doi: 10.1038/ncomms11874.

19.

Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells.

Ding L, Paszkowski-Rogacz M, Winzi M, Chakraborty D, Theis M, Singh S, Ciotta G, Poser I, Roguev A, Chu WK, Choudhary C, Mann M, Stewart AF, Krogan N, Buchholz F.

Cell Syst. 2015 Aug 26;1(2):141-51. doi: 10.1016/j.cels.2015.08.002. Epub 2015 Aug 26.

20.

PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins.

Guerrera D, Shah J, Vasileva E, Sluysmans S, Méan I, Jond L, Poser I, Mann M, Hyman AA, Citi S.

J Biol Chem. 2016 May 20;291(21):11016-29. doi: 10.1074/jbc.M115.712935. Epub 2016 Apr 4.

21.

SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export.

Müller-McNicoll M, Botti V, de Jesus Domingues AM, Brandl H, Schwich OD, Steiner MC, Curk T, Poser I, Zarnack K, Neugebauer KM.

Genes Dev. 2016 Mar 1;30(5):553-66. doi: 10.1101/gad.276477.115.

22.

CPAP promotes timely cilium disassembly to maintain neural progenitor pool.

Gabriel E, Wason A, Ramani A, Gooi LM, Keller P, Pozniakovsky A, Poser I, Noack F, Telugu NS, Calegari F, Šarić T, Hescheler J, Hyman AA, Gottardo M, Callaini G, Alkuraya FS, Gopalakrishnan J.

EMBO J. 2016 Apr 15;35(8):803-19. doi: 10.15252/embj.201593679. Epub 2016 Feb 29.

23.

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

Varier RA, Carrillo de Santa Pau E, van der Groep P, Lindeboom RG, Matarese F, Mensinga A, Smits AH, Edupuganti RR, Baltissen MP, Jansen PW, Ter Hoeve N, van Weely DR, Poser I, van Diest PJ, Stunnenberg HG, Vermeulen M.

J Biol Chem. 2016 Apr 1;291(14):7313-24. doi: 10.1074/jbc.M115.701227. Epub 2016 Feb 3.

24.

Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission.

Uehara R, Kamasaki T, Hiruma S, Poser I, Yoda K, Yajima J, Gerlich DW, Goshima G.

Mol Biol Cell. 2016 Mar 1;27(5):812-27. doi: 10.1091/mbc.E15-02-0101. Epub 2016 Jan 13.

25.

The Significance of Accurate Determination of Gleason Score for Therapeutic Options and Prognosis of Prostate Cancer.

Helpap B, Ringli D, Tonhauser J, Poser I, Breul J, Gevensleben H, Seifert HH.

Pathol Oncol Res. 2016 Apr;22(2):349-56. doi: 10.1007/s12253-015-0013-x. Epub 2015 Nov 12.

PMID:
26563277
26.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M.

Cell. 2015 Oct 22;163(3):712-23. doi: 10.1016/j.cell.2015.09.053. Epub 2015 Oct 22.

27.

The Value of Prognostic Grouping of Prostatic Carcinomas for Urologists and Pathologists.

Helpap B, Ringli D, Breul J, Tonhauser J, Poser I, Seifert HH.

Urol Int. 2015;95(4):436-44. doi: 10.1159/000437170. Epub 2015 Sep 9.

PMID:
26346556
28.

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.

Patel A, Lee HO, Jawerth L, Maharana S, Jahnel M, Hein MY, Stoynov S, Mahamid J, Saha S, Franzmann TM, Pozniakovski A, Poser I, Maghelli N, Royer LA, Weigert M, Myers EW, Grill S, Drechsel D, Hyman AA, Alberti S.

Cell. 2015 Aug 27;162(5):1066-77. doi: 10.1016/j.cell.2015.07.047.

29.

Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules.

Kroschwald S, Maharana S, Mateju D, Malinovska L, Nüske E, Poser I, Richter D, Alberti S.

Elife. 2015 Aug 4;4:e06807. doi: 10.7554/eLife.06807.

30.

FBXW7 and USP7 regulate CCDC6 turnover during the cell cycle and affect cancer drugs susceptibility in NSCLC.

Morra F, Luise C, Merolla F, Poser I, Visconti R, Ilardi G, Paladino S, Inuzuka H, Guggino G, Monaco R, Colecchia D, Monaco G, Cerrato A, Chiariello M, Denning K, Claudio PP, Staibano S, Celetti A.

Oncotarget. 2015 May 20;6(14):12697-709.

31.

Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.

Tomasovic A, Kurrle N, Sürün D, Heidler J, Husnjak K, Poser I, Schnütgen F, Scheibe S, Seimetz M, Jaksch P, Hyman A, Weissmann N, von Melchner H.

J Biol Chem. 2015 Apr 10;290(15):9738-52. doi: 10.1074/jbc.M114.632133. Epub 2015 Feb 25.

32.

Quantitative comparison of a human cancer cell surface proteome between interphase and mitosis.

Özlü N, Qureshi MH, Toyoda Y, Renard BY, Mollaoglu G, Özkan NE, Bulbul S, Poser I, Timm W, Hyman AA, Mitchison TJ, Steen JA.

EMBO J. 2015 Jan 13;34(2):251-65. doi: 10.15252/embj.201385162. Epub 2014 Dec 4.

33.

MBD5 and MBD6 interact with the human PR-DUB complex through their methyl-CpG-binding domain.

Baymaz HI, Fournier A, Laget S, Ji Z, Jansen PW, Smits AH, Ferry L, Mensinga A, Poser I, Sharrocks A, Defossez PA, Vermeulen M.

Proteomics. 2014 Oct;14(19):2179-89. doi: 10.1002/pmic.201400013. Epub 2014 Apr 24.

PMID:
24634419
34.

Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis.

Zheng X, Gooi LM, Wason A, Gabriel E, Mehrjardi NZ, Yang Q, Zhang X, Debec A, Basiri ML, Avidor-Reiss T, Pozniakovsky A, Poser I, Saric T, Hyman AA, Li H, Gopalakrishnan J.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):E354-63. doi: 10.1073/pnas.1317535111. Epub 2014 Jan 2.

35.

C11ORF24 is a novel type I membrane protein that cycles between the Golgi apparatus and the plasma membrane in Rab6-positive vesicles.

Fraisier V, Kasri A, Miserey-Lenkei S, Sibarita JB, Nair D, Mayeux A, Bardin S, Toyoda Y, Poser I, Poznyakovskiy A, Goud B, Hyman AA, Dimitrov A.

PLoS One. 2013 Dec 2;8(12):e82223. doi: 10.1371/journal.pone.0082223. eCollection 2013.

36.

The human cap-binding complex is functionally connected to the nuclear RNA exosome.

Andersen PR, Domanski M, Kristiansen MS, Storvall H, Ntini E, Verheggen C, Schein A, Bunkenborg J, Poser I, Hallais M, Sandberg R, Hyman A, LaCava J, Rout MP, Andersen JS, Bertrand E, Jensen TH.

Nat Struct Mol Biol. 2013 Dec;20(12):1367-76. doi: 10.1038/nsmb.2703. Epub 2013 Nov 24.

37.

The C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing.

Hnilicová J, Hozeifi S, Stejskalová E, Dušková E, Poser I, Humpolíčková J, Hof M, Staněk D.

Mol Biol Cell. 2013 Nov;24(22):3557-68. doi: 10.1091/mbc.E13-06-0303. Epub 2013 Sep 18.

38.

A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis.

Zanin E, Desai A, Poser I, Toyoda Y, Andree C, Moebius C, Bickle M, Conradt B, Piekny A, Oegema K.

Dev Cell. 2013 Sep 16;26(5):496-510. doi: 10.1016/j.devcel.2013.08.005. Epub 2013 Sep 5.

39.

Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase.

Uehara R, Tsukada Y, Kamasaki T, Poser I, Yoda K, Gerlich DW, Goshima G.

J Cell Biol. 2013 Aug 19;202(4):623-36. doi: 10.1083/jcb.201302123.

40.

Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment.

Jeffery JM, Grigoriev I, Poser I, van der Horst A, Hamilton N, Waterhouse N, Bleier J, Subramaniam VN, Maly IV, Akhmanova A, Khanna KK.

Cell Cycle. 2013 Mar 15;12(6):899-906. doi: 10.4161/cc.23879. Epub 2013 Feb 26.

41.

A genomic toolkit to investigate kinesin and myosin motor function in cells.

Maliga Z, Junqueira M, Toyoda Y, Ettinger A, Mora-Bermúdez F, Klemm RW, Vasilj A, Guhr E, Ibarlucea-Benitez I, Poser I, Bonifacio E, Huttner WB, Shevchenko A, Hyman AA.

Nat Cell Biol. 2013 Mar;15(3):325-34. doi: 10.1038/ncb2689. Epub 2013 Feb 17.

PMID:
23417121
42.

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS.

Cell. 2013 Feb 14;152(4):909-22. doi: 10.1016/j.cell.2013.01.030. Epub 2013 Feb 8.

43.

Stoichiometry of chromatin-associated protein complexes revealed by label-free quantitative mass spectrometry-based proteomics.

Smits AH, Jansen PW, Poser I, Hyman AA, Vermeulen M.

Nucleic Acids Res. 2013 Jan 7;41(1):e28. doi: 10.1093/nar/gks941. Epub 2012 Oct 12.

44.

APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex.

Uzunova K, Dye BT, Schutz H, Ladurner R, Petzold G, Toyoda Y, Jarvis MA, Brown NG, Poser I, Novatchkova M, Mechtler K, Hyman AA, Stark H, Schulman BA, Peters JM.

Nat Struct Mol Biol. 2012 Nov;19(11):1116-23. doi: 10.1038/nsmb.2412. Epub 2012 Sep 24.

45.

BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures.

Splinter D, Razafsky DS, Schlager MA, Serra-Marques A, Grigoriev I, Demmers J, Keijzer N, Jiang K, Poser I, Hyman AA, Hoogenraad CC, King SJ, Akhmanova A.

Mol Biol Cell. 2012 Nov;23(21):4226-41. doi: 10.1091/mbc.E12-03-0210. Epub 2012 Sep 5.

46.

Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores.

Wurzenberger C, Held M, Lampson MA, Poser I, Hyman AA, Gerlich DW.

J Cell Biol. 2012 Jul 23;198(2):173-83. doi: 10.1083/jcb.201112112. Epub 2012 Jul 16.

47.

Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions.

Frost A, Elgort MG, Brandman O, Ives C, Collins SR, Miller-Vedam L, Weibezahn J, Hein MY, Poser I, Mann M, Hyman AA, Weissman JS.

Cell. 2012 Jun 8;149(6):1339-52. doi: 10.1016/j.cell.2012.04.028.

48.

ARF6 GTPase protects the post-mitotic midbody from 14-3-3-mediated disintegration.

Joseph N, Hutterer A, Poser I, Mishima M.

EMBO J. 2012 May 30;31(11):2604-14. doi: 10.1038/emboj.2012.139. Epub 2012 May 11.

49.

Systematic phosphorylation analysis of human mitotic protein complexes.

Hegemann B, Hutchins JR, Hudecz O, Novatchkova M, Rameseder J, Sykora MM, Liu S, Mazanek M, Lénárt P, Hériché JK, Poser I, Kraut N, Hyman AA, Yaffe MB, Mechtler K, Peters JM.

Sci Signal. 2011 Nov 8;4(198):rs12. doi: 10.1126/scisignal.2001993.

50.

Large-scale de novo prediction of physical protein-protein association.

Elefsinioti A, Saraç ÖS, Hegele A, Plake C, Hubner NC, Poser I, Sarov M, Hyman A, Mann M, Schroeder M, Stelzl U, Beyer A.

Mol Cell Proteomics. 2011 Nov;10(11):M111.010629. doi: 10.1074/mcp.M111.010629. Epub 2011 Aug 11.

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