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Items: 1 to 50 of 63

1.

OutCyte: a novel tool for predicting unconventional protein secretion.

Zhao L, Poschmann G, Waldera-Lupa D, Rafiee N, Kollmann M, Stühler K.

Sci Rep. 2019 Dec 19;9(1):19448. doi: 10.1038/s41598-019-55351-z.

2.

Unconventional protein secretion: The hidden pathways.

Stühler K, Schipper K, Poschmann G.

Biochim Biophys Acta Proteins Proteom. 2019 Dec;1867(12):140272. doi: 10.1016/j.bbapap.2019.140272. Epub 2019 Sep 6. No abstract available.

PMID:
31499220
3.

Shaping the lipid composition of bacterial membranes for membrane protein production.

Kanonenberg K, Royes J, Kedrov A, Poschmann G, Angius F, Solgadi A, Spitz O, Kleinschrodt D, Stühler K, Miroux B, Schmitt L.

Microb Cell Fact. 2019 Aug 10;18(1):131. doi: 10.1186/s12934-019-1182-1.

4.

Pitfalls and opportunities in the characterization of unconventionally secreted proteins by secretome analysis.

Schira-Heinen J, Grube L, Waldera-Lupa DM, Baberg F, Langini M, Etemad-Parishanzadeh O, Poschmann G, Stühler K.

Biochim Biophys Acta Proteins Proteom. 2019 Dec;1867(12):140237. doi: 10.1016/j.bbapap.2019.06.004. Epub 2019 Jun 12. Review.

PMID:
31202002
5.

Adipokinome Signatures in Obese Mouse Models Reflect Adipose Tissue Health and Are Associated with Serum Lipid Composition.

Knebel B, Fahlbusch P, Poschmann G, Dille M, Wahlers N, Stühler K, Hartwig S, Lehr S, Schiller M, Jacob S, Kettel U, Müller-Wieland D, Kotzka J.

Int J Mol Sci. 2019 May 24;20(10). pii: E2559. doi: 10.3390/ijms20102559.

6.

HDAC5 Expression in Urothelial Carcinoma Cell Lines Inhibits Long-Term Proliferation but Can Promote Epithelial-to-Mesenchymal Transition.

Jaguva Vasudevan AA, Hoffmann MJ, Beck MLC, Poschmann G, Petzsch P, Wiek C, Stühler K, Köhrer K, Schulz WA, Niegisch G.

Int J Mol Sci. 2019 Apr 30;20(9). pii: E2135. doi: 10.3390/ijms20092135.

7.

Control of Drosophila Growth and Survival by the Lipid Droplet-Associated Protein CG9186/Sturkopf.

Werthebach M, Stewart FA, Gahlen A, Mettler-Altmann T, Akhtar I, Maas-Enriquez K, Droste A, Eichmann TO, Poschmann G, Stühler K, Beller M.

Cell Rep. 2019 Mar 26;26(13):3726-3740.e7. doi: 10.1016/j.celrep.2019.02.110.

8.

Quantitative insights into the cyanobacterial cell economy.

Zavřel T, Faizi M, Loureiro C, Poschmann G, Stühler K, Sinetova M, Zorina A, Steuer R, Červený J.

Elife. 2019 Feb 4;8. pii: e42508. doi: 10.7554/eLife.42508.

9.

A Proteome Approach Reveals Differences between Fertile Women and Patients with Repeated Implantation Failure on Endometrial Level⁻Does hCG Render the Endometrium of RIF Patients?

Bielfeld AP, Pour SJ, Poschmann G, Stühler K, Krüssel JS, Baston-Büst DM.

Int J Mol Sci. 2019 Jan 19;20(2). pii: E425. doi: 10.3390/ijms20020425.

10.

Secretome analysis of nerve repair mediating Schwann cells reveals Smad-dependent trophism.

Schira J, Heinen A, Poschmann G, Ziegler B, Hartung HP, Stühler K, Küry P.

FASEB J. 2019 Apr;33(4):4703-4715. doi: 10.1096/fj.201801799R. Epub 2018 Dec 28.

PMID:
30592632
11.

Cholestasis induced liver pathology results in dysfunctional immune responses after arenavirus infection.

Lang E, Pozdeev VI, Shinde PV, Xu HC, Sundaram B, Zhuang Y, Poschmann G, Huang J, Stühler K, Pandyra AA, Keitel V, Häussinger D, Lang KS, Lang PA.

Sci Rep. 2018 Aug 15;8(1):12179. doi: 10.1038/s41598-018-30627-y.

12.

Laminin-521 promotes quiescence in isolated stellate cells from rat liver.

Rohn F, Kordes C, Castoldi M, Götze S, Poschmann G, Stühler K, Herebian D, Benk AS, Geiger F, Zhang T, Spatz JP, Häussinger D.

Biomaterials. 2018 Oct;180:36-51. doi: 10.1016/j.biomaterials.2018.07.008. Epub 2018 Jul 7.

PMID:
30014965
13.

Corrigendum to 'Impaired Ca2+ cycling of nonischemic myocytes contributes to sarcomere dysfunction early after myocardial infarction' [J. Mol. Cell. Cardiol. 119 (2018) 28-39].

Kronenbitter A, Funk F, Hackert K, Gorreßen S, Glaser D, Boknik P, Poschmann G, Stühler K, Isić M, Krüger M, Schmitt JP.

J Mol Cell Cardiol. 2018 Aug;121:304. doi: 10.1016/j.yjmcc.2018.06.004. Epub 2018 Jun 12. No abstract available.

PMID:
29907408
14.

Impaired Ca2+ cycling of nonischemic myocytes contributes to sarcomere dysfunction early after myocardial infarction.

Kronenbitter A, Funk F, Hackert K, Gorreßen S, Glaser D, Boknik P, Poschmann G, Stühler K, Isić M, Krüger M, Schmitt JP.

J Mol Cell Cardiol. 2018 Jun;119:28-39. doi: 10.1016/j.yjmcc.2018.04.004. Epub 2018 Apr 16. Erratum in: J Mol Cell Cardiol. 2018 Aug;121:304.

PMID:
29674140
15.

Targeting liver sinusoidal endothelial cells with miR-20a-loaded nanoparticles reduces murine colon cancer metastasis to the liver.

Marquez J, Fernandez-Piñeiro I, Araúzo-Bravo MJ, Poschmann G, Stühler K, Khatib AM, Sanchez A, Unda F, Ibarretxe G, Bernales I, Badiola I.

Int J Cancer. 2018 Aug 1;143(3):709-719. doi: 10.1002/ijc.31343. Epub 2018 Mar 15.

16.

CDH13 abundance interferes with adipocyte differentiation and is a novel biomarker for adipose tissue health.

Göddeke S, Knebel B, Fahlbusch P, Hörbelt T, Poschmann G, van de Velde F, Benninghoff T, Al-Hasani H, Jacob S, Van Nieuwenhove Y, Lapauw B, Lehr S, Ouwens DM, Kotzka J.

Int J Obes (Lond). 2018 Jun;42(5):1039-1050. doi: 10.1038/s41366-018-0022-4. Epub 2018 Feb 21.

PMID:
29467502
17.

Mining the Secretome of C2C12 Muscle Cells: Data Dependent Experimental Approach To Analyze Protein Secretion Using Label-Free Quantification and Peptide Based Analysis.

Grube L, Dellen R, Kruse F, Schwender H, Stühler K, Poschmann G.

J Proteome Res. 2018 Feb 2;17(2):879-890. doi: 10.1021/acs.jproteome.7b00684. Epub 2018 Jan 24.

PMID:
29322779
18.

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.

Ingold I, Berndt C, Schmitt S, Doll S, Poschmann G, Buday K, Roveri A, Peng X, Porto Freitas F, Seibt T, Mehr L, Aichler M, Walch A, Lamp D, Jastroch M, Miyamoto S, Wurst W, Ursini F, Arnér ESJ, Fradejas-Villar N, Schweizer U, Zischka H, Friedmann Angeli JP, Conrad M.

Cell. 2018 Jan 25;172(3):409-422.e21. doi: 10.1016/j.cell.2017.11.048. Epub 2017 Dec 28.

19.

Genetic profiling and surface proteome analysis of human atrial stromal cells and rat ventricular epicardium-derived cells reveals novel insights into their cardiogenic potential.

Temme S, Friebe D, Schmidt T, Poschmann G, Hesse J, Steckel B, Stühler K, Kunz M, Dandekar T, Ding Z, Akhyari P, Lichtenberg A, Schrader J.

Stem Cell Res. 2017 Dec;25:183-190. doi: 10.1016/j.scr.2017.11.006. Epub 2017 Nov 7.

20.

Evaluation of Decellularized Porcine Jejunum as a Matrix for Lacrimal Gland Reconstruction In Vitro for Treatment of Dry Eye Syndrome.

Massie I, Spaniol K, Barbian A, Poschmann G, Stühler K, Geerling G, Metzger M, Mertsch S, Schrader S.

Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5564-5574. doi: 10.1167/iovs.16-20759.

PMID:
29079859
21.

Progesterone receptor membrane component 1 is phosphorylated upon progestin treatment in breast cancer cells.

Willibald M, Bayer G, Stahlhut V, Poschmann G, Stühler K, Gierke B, Pawlak M, Seeger H, Mueck AO, Niederacher D, Fehm T, Neubauer H.

Oncotarget. 2017 Aug 2;8(42):72480-72493. doi: 10.18632/oncotarget.19819. eCollection 2017 Sep 22.

22.

Massive Protein Import into the Early-Evolutionary-Stage Photosynthetic Organelle of the Amoeba Paulinella chromatophora.

Singer A, Poschmann G, Mühlich C, Valadez-Cano C, Hänsch S, Hüren V, Rensing SA, Stühler K, Nowack ECM.

Curr Biol. 2017 Sep 25;27(18):2763-2773.e5. doi: 10.1016/j.cub.2017.08.010. Epub 2017 Sep 7.

23.

Novel Insights into the Adipokinome of Obese and Obese/Diabetic Mouse Models.

Knebel B, Goeddeke S, Poschmann G, Markgraf DF, Jacob S, Nitzgen U, Passlack W, Preuss C, Dicken HD, Stühler K, Hartwig S, Lehr S, Kotzka J.

Int J Mol Sci. 2017 Sep 8;18(9). pii: E1928. doi: 10.3390/ijms18091928.

24.

The ancestors of diatoms evolved a unique mitochondrial dehydrogenase to oxidize photorespiratory glycolate.

Schmitz J, Srikanth NV, Hüdig M, Poschmann G, Lercher MJ, Maurino VG.

Photosynth Res. 2017 May;132(2):183-196. doi: 10.1007/s11120-017-0355-1. Epub 2017 Feb 28.

PMID:
28247236
25.

Succession of splicing regulatory elements determines cryptic 5΄ss functionality.

Brillen AL, Schöneweis K, Walotka L, Hartmann L, Müller L, Ptok J, Kaisers W, Poschmann G, Stühler K, Buratti E, Theiss S, Schaal H.

Nucleic Acids Res. 2017 Apr 20;45(7):4202-4216. doi: 10.1093/nar/gkw1317.

26.

A Luciferase-fragment Complementation Assay to Detect Lipid Droplet-associated Protein-Protein Interactions.

Kolkhof P, Werthebach M, van de Venn A, Poschmann G, Chen L, Welte M, Stühler K, Beller M.

Mol Cell Proteomics. 2017 Mar;16(3):329-345. doi: 10.1074/mcp.M116.061499. Epub 2016 Dec 12.

27.

Glyoxalase 1-knockdown in human aortic endothelial cells - effect on the proteome and endothelial function estimates.

Stratmann B, Engelbrecht B, Espelage BC, Klusmeier N, Tiemann J, Gawlowski T, Mattern Y, Eisenacher M, Meyer HE, Rabbani N, Thornalley PJ, Tschoepe D, Poschmann G, Stühler K.

Sci Rep. 2016 Nov 29;6:37737. doi: 10.1038/srep37737.

28.

Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.

Trossbach SV, Bader V, Hecher L, Pum ME, Masoud ST, Prikulis I, Schäble S, de Souza Silva MA, Su P, Boulat B, Chwiesko C, Poschmann G, Stühler K, Lohr KM, Stout KA, Oskamp A, Godsave SF, Müller-Schiffmann A, Bilzer T, Steiner H, Peters PJ, Bauer A, Sauvage M, Ramsey AJ, Miller GW, Liu F, Seeman P, Brandon NJ, Huston JP, Korth C.

Mol Psychiatry. 2016 Nov;21(11):1561-1572. doi: 10.1038/mp.2015.194. Epub 2016 Jan 12.

29.

The Cytoskeleton of Parabasalian Parasites Comprises Proteins that Share Properties Common to Intermediate Filament Proteins.

Preisner H, Karin EL, Poschmann G, Stühler K, Pupko T, Gould SB.

Protist. 2016 Dec;167(6):526-543. doi: 10.1016/j.protis.2016.09.001. Epub 2016 Sep 16.

30.

Evaluation of the biomarker candidate MFAP4 for non-invasive assessment of hepatic fibrosis in hepatitis C patients.

Bracht T, Mölleken C, Ahrens M, Poschmann G, Schlosser A, Eisenacher M, Stühler K, Meyer HE, Schmiegel WH, Holmskov U, Sorensen GL, Sitek B.

J Transl Med. 2016 Jul 4;14(1):201. doi: 10.1186/s12967-016-0952-3.

31.

Interdomain regulation of the ATPase activity of the ABC transporter haemolysin B from Escherichia coli.

Reimann S, Poschmann G, Kanonenberg K, Stühler K, Smits SH, Schmitt L.

Biochem J. 2016 Aug 15;473(16):2471-83. doi: 10.1042/BCJ20160154. Epub 2016 Jun 8.

PMID:
27279651
32.

PsbS interactions involved in the activation of energy dissipation in Arabidopsis.

Correa-Galvis V, Poschmann G, Melzer M, Stühler K, Jahns P.

Nat Plants. 2016 Feb 1;2:15225. doi: 10.1038/nplants.2015.225.

PMID:
27249196
33.

Minichromosome Maintenance Complex Is a Critical Node in the miR-183 Signaling Network of MYCN-Amplified Neuroblastoma Cells.

Lodrini M, Poschmann G, Schmidt V, Wünschel J, Dreidax D, Witt O, Höfer T, Meyer HE, Stühler K, Eggert A, Deubzer HE.

J Proteome Res. 2016 Jul 1;15(7):2178-86. doi: 10.1021/acs.jproteome.6b00134. Epub 2016 Jun 9.

PMID:
27239679
34.

MFAP4: a candidate biomarker for hepatic and pulmonary fibrosis?

Mölleken C, Poschmann G, Bonella F, Costabel U, Sitek B, Stühler K, Meyer HE, Schmiegel WH, Marcussen N, Helmer M, Nielsen O, Hansen S, Schlosser A, Holmskov U, Sorensen GL.

Sarcoidosis Vasc Diffuse Lung Dis. 2016 Mar 29;33(1):41-50.

PMID:
27055835
35.

Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin.

Waldera Lupa DM, Kalfalah F, Safferling K, Boukamp P, Poschmann G, Volpi E, Götz-Rösch C, Bernerd F, Haag L, Huebenthal U, Fritsche E, Boege F, Grabe N, Tigges J, Stühler K, Krutmann J.

J Invest Dermatol. 2015 Aug;135(8):1954-1968. doi: 10.1038/jid.2015.120. Epub 2015 Mar 27.

36.

Redox proteomics reveal stress responsive proteins linking peroxiredoxin-1 status in glioma to chemosensitivity and oxidative stress.

Poschmann G, Grzendowski M, Stefanski A, Bruns E, Meyer HE, Stühler K.

Biochim Biophys Acta. 2015 Jun;1854(6):624-31. doi: 10.1016/j.bbapap.2014.11.011. Epub 2014 Dec 4.

PMID:
25484280
37.

The development of diet-induced obesity and associated metabolic impairments in Dj-1 deficient mice.

Seyfarth K, Poschmann G, Rozman J, Fromme T, Rink N, Hofmann A, Wurst W, Stühler K, Klingenspor M.

J Nutr Biochem. 2015 Jan;26(1):75-81. doi: 10.1016/j.jnutbio.2014.09.002. Epub 2014 Oct 2.

PMID:
25448609
38.

Identification of novel adipokines differential regulated in C57BL/Ks and C57BL/6.

Hartwig S, Goeddeke S, Poschmann G, Dicken HD, Jacob S, Nitzgen U, Passlack W, Stühler K, Ouwens DM, Al-Hasani H, Knebel B, Kotzka J, Lehr S.

Arch Physiol Biochem. 2014 Dec;120(5):208-15. doi: 10.3109/13813455.2014.970197. Epub 2014 Oct 16.

PMID:
25319219
39.

Zebrafish heart development is regulated via glutaredoxin 2 dependent migration and survival of neural crest cells.

Berndt C, Poschmann G, Stühler K, Holmgren A, Bräutigam L.

Redox Biol. 2014 May 2;2:673-8. doi: 10.1016/j.redox.2014.04.012. eCollection 2014.

40.

High-fat diet induced isoform changes of the Parkinson's disease protein DJ-1.

Poschmann G, Seyfarth K, Besong Agbo D, Klafki HW, Rozman J, Wurst W, Wiltfang J, Meyer HE, Klingenspor M, Stühler K.

J Proteome Res. 2014 May 2;13(5):2339-51. doi: 10.1021/pr401157k. Epub 2014 Mar 28.

PMID:
24646099
41.

Biomarkers: a proteomic challenge. Preface.

Stühler K, Poschmann G.

Biochim Biophys Acta. 2014 May;1844(5):859-60. doi: 10.1016/j.bbapap.2014.02.020. Epub 2014 Feb 28. No abstract available.

PMID:
24590111
42.

Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1.

Bräutigam L, Jensen LD, Poschmann G, Nyström S, Bannenberg S, Dreij K, Lepka K, Prozorovski T, Montano SJ, Aktas O, Uhlén P, Stühler K, Cao Y, Holmgren A, Berndt C.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20057-62. doi: 10.1073/pnas.1313753110. Epub 2013 Nov 25.

43.

Development of a capillary isoelectric focusing immunoassay to measure DJ-1 isoforms in biological samples.

Besong Agbo D, Klafki H, Poschmann G, Seyfarth K, Genius J, Janßen C, Stühler K, Wurst W, Meyer HE, Klingenspor M, Wiltfang J.

Anal Biochem. 2013 Dec 15;443(2):197-204. doi: 10.1016/j.ab.2013.09.013. Epub 2013 Sep 17.

PMID:
24055619
44.

A combination of two electrophoretical approaches for detailed proteome-based characterization of SCLC subtypes.

Poschmann G, Lendzian A, Uszkoreit J, Eisenacher M, Borght AV, Ramaekers FC, Meyer HE, Stühler K.

Arch Physiol Biochem. 2013 Jul;119(3):114-25. doi: 10.3109/13813455.2013.789529. Epub 2013 May 8.

PMID:
23651173
45.

Tra2-mediated recognition of HIV-1 5' splice site D3 as a key factor in the processing of vpr mRNA.

Erkelenz S, Poschmann G, Theiss S, Stefanski A, Hillebrand F, Otte M, Stühler K, Schaal H.

J Virol. 2013 Mar;87(5):2721-34. doi: 10.1128/JVI.02756-12. Epub 2012 Dec 19.

46.

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.

Gregory AP, Dendrou CA, Attfield KE, Haghikia A, Xifara DK, Butter F, Poschmann G, Kaur G, Lambert L, Leach OA, Prömel S, Punwani D, Felce JH, Davis SJ, Gold R, Nielsen FC, Siegel RM, Mann M, Bell JI, McVean G, Fugger L.

Nature. 2012 Aug 23;488(7412):508-511. doi: 10.1038/nature11307.

47.

Application of label-free proteomics for differential analysis of lung carcinoma cell line A549.

Sitek B, Waldera-Lupa DM, Poschmann G, Meyer HE, Stühler K.

Methods Mol Biol. 2012;893:241-8. doi: 10.1007/978-1-61779-885-6_16.

PMID:
22665305
48.

Application of saturation labeling in lung cancer proteomics.

Poschmann G, Sitek B, Sipos B, Stühler K.

Methods Mol Biol. 2012;854:253-67. doi: 10.1007/978-1-61779-573-2_18.

PMID:
22311766
49.

The proteomic signature of insulin-resistant human skeletal muscle reveals increased glycolytic and decreased mitochondrial enzymes.

Giebelstein J, Poschmann G, Højlund K, Schechinger W, Dietrich JW, Levin K, Beck-Nielsen H, Podwojski K, Stühler K, Meyer HE, Klein HH.

Diabetologia. 2012 Apr;55(4):1114-27. doi: 10.1007/s00125-012-2456-x. Epub 2012 Jan 27. Erratum in: Diabetologia. 2012 Jul;55(7):2083.

PMID:
22282162
50.

Analysis of the pancreatic tumor progression by a quantitative proteomic approach and immunhistochemical validation.

Sitek B, Sipos B, Alkatout I, Poschmann G, Stephan C, Schulenborg T, Marcus K, Lüttges J, Dittert DD, Baretton G, Schmiegel W, Hahn SA, Klöppel G, Meyer HE, Stühler K.

J Proteome Res. 2009 Apr;8(4):1647-56. doi: 10.1021/pr800890j.

PMID:
19714807

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