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Items: 1 to 50 of 52

1.

Potentially actionable FGFR2 high-level amplification in thymic sebaceous carcinoma.

Porubsky S, Jessup P, Kee D, Sharma R, Ochi A, Xu H, Froelich JJ, Nott L, Scott C, Awad R, Moldovan C, Hardikar AA, Bohnenberger H, Küffer S, Ströbel P, Marx A.

Virchows Arch. 2019 Aug 10. doi: 10.1007/s00428-019-02644-3. [Epub ahead of print]

PMID:
31401665
2.

Systematic prostate biopsy still matters: A comprehensive analysis of MRI/TRUS-fusion targeted prostate biopsies across different indications.

Westhoff N, Baeßler B, von Hardenberg J, Hetjens S, Porubsky S, Siegel F, Martini T, Michel MS, Attenberger U, Ritter M.

Urol Oncol. 2019 Oct;37(10):678-687. doi: 10.1016/j.urolonc.2019.07.004. Epub 2019 Jul 31.

PMID:
31375340
3.

EWSR1 translocation in primary hyalinising clear cell carcinoma of the thymus.

Porubsky S, Rudolph B, Rückert JC, Küffer S, Ströbel P, Roden AC, Jain D, Tousseyn T, Van Veer H, Huang J, Antonicelli A, Kuo TT, Rosai J, Marx A; International Thymic Malignancy Interest Group (ITMIG).

Histopathology. 2019 Sep;75(3):431-436. doi: 10.1111/his.13890. Epub 2019 Jul 19.

PMID:
31050844
4.

Quantitative assessment of microperfusion by indocyanine green angiography in kidney transplantation resembles chronic morphological changes in kidney specimens.

Rother U, Amann K, Adler W, Nawroth N, Karampinis I, Keese M, Manap S, Regus S, Meyer A, Porubsky S, Hilgers K, Krämer BK, Lang W, Nowak K, Gerken ALH.

Microcirculation. 2019 Apr;26(3):e12529. doi: 10.1111/micc.12529. Epub 2019 Feb 8.

PMID:
30656790
5.

Association of training level and outcome of software-based image fusion-guided targeted prostate biopsies.

Westhoff N, Haumann H, Kriegmair MC, von Hardenberg J, Budjan J, Porubsky S, Michel MS, Honeck P, Ritter M.

World J Urol. 2019 Oct;37(10):2119-2127. doi: 10.1007/s00345-018-2605-z. Epub 2018 Dec 17.

PMID:
30560300
6.

Renal outcomes of STOP-IgAN trial patients in relation to baseline histology (MEST-C scores).

Schimpf JI, Klein T, Fitzner C, Eitner F, Porubsky S, Hilgers RD, Floege J, Groene HJ, Rauen T.

BMC Nephrol. 2018 Nov 19;19(1):328. doi: 10.1186/s12882-018-1128-6.

7.

Influence of symptomatic pseudoaneurysms on postoperative renal function after partial nephrectomy: results of a matched pair analysis.

Walach MT, Rathmann N, Porubsky S, Pfalzgraf D, Diehl SJ, Ritter M, Michel MS, Wagener N, Honeck P, Kriegmair MC.

Int Urol Nephrol. 2019 Jan;51(1):33-40. doi: 10.1007/s11255-018-2024-5. Epub 2018 Nov 12.

PMID:
30421098
8.

mRNA-Expression of KRT5 and KRT20 Defines Distinct Prognostic Subgroups of Muscle-Invasive Urothelial Bladder Cancer Correlating with Histological Variants.

Eckstein M, Wirtz RM, Gross-Weege M, Breyer J, Otto W, Stoehr R, Sikic D, Keck B, Eidt S, Burger M, Bolenz C, Nitschke K, Porubsky S, Hartmann A, Erben P.

Int J Mol Sci. 2018 Oct 30;19(11). pii: E3396. doi: 10.3390/ijms19113396.

9.

Prostate cancer treatment by the latest focal HIFU device with MRI/TRUS-fusion control biopsies: A prospective evaluation.

von Hardenberg J, Westhoff N, Baumunk D, Hausmann D, Martini T, Marx A, Porubsky S, Schostak M, Michel MS, Ritter M.

Urol Oncol. 2018 Sep;36(9):401.e1-401.e9. doi: 10.1016/j.urolonc.2018.05.022. Epub 2018 Aug 6.

PMID:
30093211
10.

Defining the target prior to prostate fusion biopsy: the effect of MRI reporting on cancer detection.

Westhoff N, Siegel F, Peter C, Hetjens S, Porubsky S, Martini T, von Hardenberg J, Michel MS, Budjan J, Ritter M.

World J Urol. 2019 Feb;37(2):327-335. doi: 10.1007/s00345-018-2400-x. Epub 2018 Jul 2.

PMID:
29967946
11.

Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient.

Doll S, Kriegmair MC, Santos A, Wierer M, Coscia F, Neil HM, Porubsky S, Geyer PE, Mund A, Nuhn P, Mann M.

Mol Oncol. 2018 Aug;12(8):1296-1307. doi: 10.1002/1878-0261.12326. Epub 2018 Jun 14.

12.

Changes in CD73, CD39 and CD26 expression on T-lymphocytes of ANCA-associated vasculitis patients suggest impairment in adenosine generation and turn-over.

Kling L, Benck U, Breedijk A, Leikeim L, Heitzmann M, Porubsky S, Krämer BK, Yard BA, Kälsch AI.

Sci Rep. 2017 Sep 15;7(1):11683. doi: 10.1038/s41598-017-12011-4.

13.

Glucosylceramide Synthase Is Involved in Development of Invariant Natural Killer T Cells.

Popovic ZV, Rabionet M, Jennemann R, Krunic D, Sandhoff R, Gröne HJ, Porubsky S.

Front Immunol. 2017 Jul 21;8:848. doi: 10.3389/fimmu.2017.00848. eCollection 2017.

14.

Metabolic Syndrome Negatively Impacts the Outcome of Localized Renal Cell Carcinoma.

Kriegmair MC, Mandel P, Porubsky S, Dürr J, Huck N, Nuhn P, Pfalzgraf D, Michel MS, Wagener N.

Horm Cancer. 2017 Apr;8(2):127-134. doi: 10.1007/s12672-017-0289-2. Epub 2017 Feb 28.

PMID:
28247362
15.

Deficiency of N-myristoylation reveals calcineurin activity as regulator of IFN-γ-producing γδ T cells.

Rampoldi F, Brunk F, Bonrouhi M, Federico G, Krunic D, Porubsky S, Gröne HJ, Popovic ZV.

J Leukoc Biol. 2017 Apr;101(4):1005-1014. doi: 10.1189/jlb.1A0616-264R. Epub 2017 Jan 6.

PMID:
28062573
16.

ELMO1 protects renal structure and ultrafiltration in kidney development and under diabetic conditions.

Sharma KR, Heckler K, Stoll SJ, Hillebrands JL, Kynast K, Herpel E, Porubsky S, Elger M, Hadaschik B, Bieback K, Hammes HP, Nawroth PP, Kroll J.

Sci Rep. 2016 Nov 16;6:37172. doi: 10.1038/srep37172.

17.

Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis.

Federico G, Meister M, Mathow D, Heine GH, Moldenhauer G, Popovic ZV, Nordström V, Kopp-Schneider A, Hielscher T, Nelson PJ, Schaefer F, Porubsky S, Fliser D, Arnold B, Gröne HJ.

JCI Insight. 2016 Jan 21;1(1):e84916. doi: 10.1172/jci.insight.84916.

18.

On-Tissue Phospholipase C Digestion for Enhanced MALDI-MS Imaging of Neutral Glycosphingolipids.

Vens-Cappell S, Kouzel IU, Kettling H, Soltwisch J, Bauwens A, Porubsky S, Müthing J, Dreisewerd K.

Anal Chem. 2016 Jun 7;88(11):5595-9. doi: 10.1021/acs.analchem.6b01084. Epub 2016 May 26.

PMID:
27212679
19.

Myf5 and Myogenin in the development of thymic myoid cells - Implications for a murine in vivo model of myasthenia gravis.

Hu B, Simon-Keller K, Küffer S, Ströbel P, Braun T, Marx A, Porubsky S.

Exp Neurol. 2016 Mar;277:76-85. doi: 10.1016/j.expneurol.2015.12.010. Epub 2015 Dec 18.

PMID:
26708556
20.

The renal microenvironment modifies dendritic cell phenotype.

Chessa F, Mathow D, Wang S, Hielscher T, Atzberger A, Porubsky S, Gretz N, Burgdorf S, Gröne HJ, Popovic ZV.

Kidney Int. 2016 Jan;89(1):82-94. doi: 10.1038/ki.2015.292. Epub 2016 Jan 4.

PMID:
26466317
21.

Immunosuppression and Aberrant T Cell Development in the Absence of N-Myristoylation.

Rampoldi F, Bonrouhi M, Boehm ME, Lehmann WD, Popovic ZV, Kaden S, Federico G, Brunk F, Gröne HJ, Porubsky S.

J Immunol. 2015 Nov 1;195(9):4228-43. doi: 10.4049/jimmunol.1500622. Epub 2015 Sep 30.

22.

Male meiotic cytokinesis requires ceramide synthase 3-dependent sphingolipids with unique membrane anchors.

Rabionet M, Bayerle A, Jennemann R, Heid H, Fuchser J, Marsching C, Porubsky S, Bolenz C, Guillou F, Gröne HJ, Gorgas K, Sandhoff R.

Hum Mol Genet. 2015 Sep 1;24(17):4792-808. doi: 10.1093/hmg/ddv204. Epub 2015 Jun 4.

PMID:
26045466
23.

Thymoma related myasthenia gravis in humans and potential animal models.

Marx A, Porubsky S, Belharazem D, Saruhan-Direskeneli G, Schalke B, Ströbel P, Weis CA.

Exp Neurol. 2015 Aug;270:55-65. doi: 10.1016/j.expneurol.2015.02.010. Epub 2015 Feb 18. Review.

PMID:
25700911
24.

Hepatitis C virus induced endothelial inflammatory response depends on the functional expression of TNFα receptor subtype 2.

Pircher J, Czermak T, Merkle M, Mannell H, Krötz F, Ribeiro A, Vielhauer V, Nadjiri J, Gaitzsch E, Niemeyer M, Porubsky S, Gröne HJ, Wörnle M.

PLoS One. 2014 Nov 24;9(11):e113351. doi: 10.1371/journal.pone.0113351. eCollection 2014.

25.

[Globosides as key players in the pathophysiology of Shiga toxin-associated acute kidney failure and Fabry disease].

Porubsky S.

Pathologe. 2014 Nov;35 Suppl 2:271-6. doi: 10.1007/s00292-014-1992-1. German.

PMID:
25348118
26.

Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.

Marsching C, Rabionet M, Mathow D, Jennemann R, Kremser C, Porubsky S, Bolenz C, Willecke K, Gröne HJ, Hopf C, Sandhoff R.

J Lipid Res. 2014 Nov;55(11):2354-69. doi: 10.1194/jlr.M051839. Epub 2014 Sep 29.

27.

The molecular phenotype of endocapillary proliferation: novel therapeutic targets for IgA nephropathy.

Hodgin JB, Berthier CC, John R, Grone E, Porubsky S, Gröne HJ, Herzenberg AM, Scholey JW, Hladunewich M, Cattran DC, Kretzler M, Reich HN.

PLoS One. 2014 Aug 18;9(8):e103413. doi: 10.1371/journal.pone.0103413. eCollection 2014.

28.

Depletion of globosides and isoglobosides fully reverts the morphologic phenotype of Fabry disease.

Porubsky S, Jennemann R, Lehmann L, Gröne HJ.

Cell Tissue Res. 2014 Oct;358(1):217-27. doi: 10.1007/s00441-014-1922-9. Epub 2014 Jul 4.

29.

Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure.

Porubsky S, Federico G, Müthing J, Jennemann R, Gretz N, Büttner S, Obermüller N, Jung O, Hauser IA, Gröne E, Geiger H, Gröne HJ, Betz C.

J Pathol. 2014 Sep;234(1):120-33. doi: 10.1002/path.4388. Epub 2014 Jul 25.

30.

Renal lipidosis in patients enrolled in a methadone substitution program.

Porubsky S, Kuppe C, Maier T, Birk HW, Wörnle M, Moeller MJ, Floege J, Gröne HJ.

Arch Pathol Lab Med. 2014 May;138(5):689-93. doi: 10.5858/arpa.2013-0075-CR.

PMID:
24786128
31.

cFLIP regulates skin homeostasis and protects against TNF-induced keratinocyte apoptosis.

Panayotova-Dimitrova D, Feoktistova M, Ploesser M, Kellert B, Hupe M, Horn S, Makarov R, Jensen F, Porubsky S, Schmieder A, Zenclussen AC, Marx A, Kerstan A, Geserick P, He YW, Leverkus M.

Cell Rep. 2013 Oct 31;5(2):397-408. doi: 10.1016/j.celrep.2013.09.035.

32.

Sulfatides are required for renal adaptation to chronic metabolic acidosis.

Stettner P, Bourgeois S, Marsching C, Traykova-Brauch M, Porubsky S, Nordström V, Hopf C, Koesters R, Sandhoff R, Wiegandt H, Wagner CA, Gröne HJ, Jennemann R.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9998-10003. doi: 10.1073/pnas.1217775110. Epub 2013 May 28. Erratum in: Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14813. Kösters, Robert [corrected to Koesters, Robert].

33.

Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells.

Porubsky S, Speak AO, Salio M, Jennemann R, Bonrouhi M, Zafarulla R, Singh Y, Dyson J, Luckow B, Lehuen A, Malle E, Müthing J, Platt FM, Cerundolo V, Gröne HJ.

J Immunol. 2012 Sep 15;189(6):3007-17. doi: 10.4049/jimmunol.1201483. Epub 2012 Aug 8.

34.

A new, robust, and nonradioactive approach for exploring N-myristoylation.

Rampoldi F, Sandhoff R, Owen RW, Gröne HJ, Porubsky S.

J Lipid Res. 2012 Nov;53(11):2459-68. doi: 10.1194/jlr.D026997. Epub 2012 Jul 24.

35.

The proteoglycan biglycan enhances antigen-specific T cell activation potentially via MyD88 and TRIF pathways and triggers autoimmune perimyocarditis.

Popovic ZV, Wang S, Papatriantafyllou M, Kaya Z, Porubsky S, Meisner M, Bonrouhi M, Burgdorf S, Young MF, Schaefer L, Gröne HJ.

J Immunol. 2011 Dec 15;187(12):6217-26. doi: 10.4049/jimmunol.1003478. Epub 2011 Nov 16.

36.

Modulation of Wnt and Hedgehog signaling pathways is linked to retinoic acid-induced amelioration of chronic allograft dysfunction.

von Toerne C, Bedke J, Safi S, Porubsky S, Gretz N, Loewe R, Nelson PJ, Gröne HJ.

Am J Transplant. 2012 Jan;12(1):55-68. doi: 10.1111/j.1600-6143.2011.03776.x. Epub 2011 Oct 12.

37.

Human renal cell carcinoma induces a dendritic cell subset that uses T-cell crosstalk for tumor-permissive milieu alterations.

Figel AM, Brech D, Prinz PU, Lettenmeyer UK, Eckl J, Turqueti-Neves A, Mysliwietz J, Anz D, Rieth N, Muenchmeier N, Buchner A, Porubsky S, Siegert SI, Segerer S, Nelson PJ, Noessner E.

Am J Pathol. 2011 Jul;179(1):436-51. doi: 10.1016/j.ajpath.2011.03.011. Epub 2011 May 18.

38.

Suppression of chronic damage in renal allografts by Liver X receptor (LXR) activation relevant contribution of macrophage LXRα.

Kiss E, Popovic Z, Bedke J, Wang S, Bonrouhi M, Gretz N, Stettner P, Teupser D, Thiery J, Porubsky S, Adams J, Gröne HJ.

Am J Pathol. 2011 Jul;179(1):92-103. doi: 10.1016/j.ajpath.2011.03.019. Epub 2011 May 5.

39.

Rhoh deficiency reduces peripheral T-cell function and attenuates allogenic transplant rejection.

Porubsky S, Wang S, Kiss E, Dehmel S, Bonrouhi M, Dorn T, Luckow B, Brakebusch C, Gröne HJ.

Eur J Immunol. 2011 Jan;41(1):76-88. doi: 10.1002/eji.201040420. Epub 2010 Nov 11.

40.

Attenuation-based characterization of coronary atherosclerotic plaque: comparison of dual source and dual energy CT with single-source CT and histopathology.

Henzler T, Porubsky S, Kayed H, Harder N, Krissak UR, Meyer M, Sueselbeck T, Marx A, Michaely H, Schoepf UJ, Schoenberg SO, Fink C.

Eur J Radiol. 2011 Oct;80(1):54-9. doi: 10.1016/j.ejrad.2010.07.024. Epub 2010 Aug 31.

PMID:
20810229
41.

Peroxisome proliferator-activated receptor (PPAR)gamma can inhibit chronic renal allograft damage.

Kiss E, Popovic ZV, Bedke J, Adams J, Bonrouhi M, Babelova A, Schmidt C, Edenhofer F, Zschiedrich I, Domhan S, Abdollahi A, Schäfer L, Gretz N, Porubsky S, Gröne HJ.

Am J Pathol. 2010 May;176(5):2150-62. doi: 10.2353/ajpath.2010.090370. Epub 2010 Apr 2.

42.

Recipient Toll-like receptors contribute to chronic graft dysfunction by both MyD88- and TRIF-dependent signaling.

Wang S, Schmaderer C, Kiss E, Schmidt C, Bonrouhi M, Porubsky S, Gretz N, Schaefer L, Kirschning CJ, Popovic ZV, Gröne HJ.

Dis Model Mech. 2010 Jan-Feb;3(1-2):92-103. doi: 10.1242/dmm.003533. Epub 2009 Dec 28.

43.

Wnt pathway regulation in chronic renal allograft damage.

von Toerne C, Schmidt C, Adams J, Kiss E, Bedke J, Porubsky S, Gretz N, Lindenmeyer MT, Cohen CD, Gröne HJ, Nelson PJ.

Am J Transplant. 2009 Oct;9(10):2223-39. doi: 10.1111/j.1600-6143.2009.02762.x. Epub 2009 Jul 22.

44.

Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans.

De Santo C, Salio M, Masri SH, Lee LY, Dong T, Speak AO, Porubsky S, Booth S, Veerapen N, Besra GS, Gröne HJ, Platt FM, Zambon M, Cerundolo V.

J Clin Invest. 2008 Dec;118(12):4036-48. doi: 10.1172/JCI36264. Epub 2008 Nov 13.

45.

[Glycosphingolipids Gb3 and iGb3. In vivo roles in hemolytic-uremic syndrome and iNKT cell function].

Porubsky S, Luckow B, Bonrouhi M, Speak A, Cerundolo V, Platt F, Gröne HJ.

Pathologe. 2008 Nov;29 Suppl 2:297-302. doi: 10.1007/s00292-008-1040-0. German.

PMID:
18810447
46.

Histiocytosis X and renal insufficiency.

Materne C, Porubsky S, Gerth J, Gröne HJ, Wolf G.

Nephrol Dial Transplant. 2007 Dec;22(12):3664-7. Epub 2007 Sep 21. No abstract available.

PMID:
17890248
47.

Abrogation of nephrotic proteinuria by rituximab treatment in a renal transplant patient with relapsed focal segmental glomerulosclerosis.

Gossmann J, Scheuermann EH, Porubsky S, Kachel HG, Geiger H, Hauser IA.

Transpl Int. 2007 Jun;20(6):558-62. Epub 2007 Apr 13.

48.

Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency.

Porubsky S, Speak AO, Luckow B, Cerundolo V, Platt FM, Gröne HJ.

Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5977-82. Epub 2007 Mar 19.

49.

Nephrotic-range proteinuria following pamidronate therapy in a patient with metastatic breast cancer: mitochondrial toxicity as a pathogenetic concept?

Sauter M, Jülg B, Porubsky S, Cohen C, Fischereder M, Sitter T, Schlondorff D, Gröne HJ.

Am J Kidney Dis. 2006 Jun;47(6):1075-80. No abstract available.

PMID:
16731304
50.

Influence of native and hypochlorite-modified low-density lipoprotein on gene expression in human proximal tubular epithelium.

Porubsky S, Schmid H, Bonrouhi M, Kretzler M, Malle E, Nelson PJ, Gröne HJ.

Am J Pathol. 2004 Jun;164(6):2175-87.

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