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Items: 1 to 50 of 61

1.

Genetic Diversity and Molecular Epidemiology of Mycobacterium tuberculosis in Roraima State, Brazil.

Tatara MB, Perdigão J, Viveiros M, Kritski A, Esther da Silva K, Correia Sacchi FP, Camioli de Lima C, Pereira Dos Santos PC, de Lourdes do Carmo Guimarães Diniz J, Almeida Silva PE, Duarte PG, Quirino Gomes MM, Totumi Cunha EA, Lapa E Silva JR, Portugal I, Croda J, Andrade MKN.

Am J Trop Med Hyg. 2019 Aug 5. doi: 10.4269/ajtmh.19-0324. [Epub ahead of print]

PMID:
31392954
2.

Azaaurones as Potent Antimycobacterial Agents Active against MDR- and XDR-TB.

Campaniço A, Carrasco MP, Njoroge M, Seldon R, Chibale K, Perdigão J, Portugal I, Warner DF, Moreira R, Lopes F.

ChemMedChem. 2019 Jul 11. doi: 10.1002/cmdc.201900289. [Epub ahead of print]

PMID:
31294529
3.

Tuberculosis caused by Mycobacterium pinnipedii in a wild South American sea lion Otaria flavescens stranded in southern Brazil.

Martins Melo A, Silva Filho RPD, von Groll A, Reis AJ, Diniz J, Perdigão J, Portugal I, da Silva PEA, Borelli Grecco F, Orzechowski Xavier M.

Dis Aquat Organ. 2019 Mar 28;133(3):189-194. doi: 10.3354/dao03342.

PMID:
31187733
4.

Evaluation of a gene-by-gene approach for prospective whole-genome sequencing-based surveillance of multidrug resistant Mycobacterium tuberculosis.

Macedo R, Pinto M, Borges V, Nunes A, Oliveira O, Portugal I, Duarte R, Gomes JP.

Tuberculosis (Edinb). 2019 Mar;115:81-88. doi: 10.1016/j.tube.2019.02.006. Epub 2019 Feb 25.

PMID:
30948181
5.

Insights on the Mycobacterium tuberculosis population structure associated with migrants from Portuguese-speaking countries over a three-year period in Greater Lisbon, Portugal: Implications at the public health level.

Pereira C, Gomes P, Taveira R, Silva C, Maltez F, Macedo R, Costa C, Couvin D, Rastogi N, Viveiros M, Perdigão J, Portugal I.

Infect Genet Evol. 2019 Jul;71:159-165. doi: 10.1016/j.meegid.2019.03.025. Epub 2019 Mar 27.

PMID:
30928606
6.

Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance.

Oppong YEA, Phelan J, Perdigão J, Machado D, Miranda A, Portugal I, Viveiros M, Clark TG, Hibberd ML.

BMC Genomics. 2019 Mar 29;20(1):252. doi: 10.1186/s12864-019-5615-3.

7.

Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation.

Brynildsrud OB, Pepperell CS, Suffys P, Grandjean L, Monteserin J, Debech N, Bohlin J, Alfsnes K, Pettersson JO, Kirkeleite I, Fandinho F, da Silva MA, Perdigao J, Portugal I, Viveiros M, Clark T, Caws M, Dunstan S, Thai PVK, Lopez B, Ritacco V, Kitchen A, Brown TS, van Soolingen D, O'Neill MB, Holt KE, Feil EJ, Mathema B, Balloux F, Eldholm V.

Sci Adv. 2018 Oct 17;4(10):eaat5869. doi: 10.1126/sciadv.aat5869. eCollection 2018 Oct.

8.

Genetics and roadblocks of drug resistant tuberculosis.

Perdigão J, Portugal I.

Infect Genet Evol. 2019 Aug;72:113-130. doi: 10.1016/j.meegid.2018.09.023. Epub 2018 Sep 24.

PMID:
30261266
9.

Dissecting whole-genome sequencing-based online tools for predicting resistance in Mycobacterium tuberculosis: can we use them for clinical decision guidance?

Macedo R, Nunes A, Portugal I, Duarte S, Vieira L, Gomes JP.

Tuberculosis (Edinb). 2018 May;110:44-51. doi: 10.1016/j.tube.2018.03.009. Epub 2018 Mar 27.

PMID:
29779772
10.

Contribution of efflux to colistin heteroresistance in a multidrug resistant Acinetobacter baumannii clinical isolate.

Machado D, Antunes J, Simões A, Perdigão J, Couto I, McCusker M, Martins M, Portugal I, Pacheco T, Batista J, Toscano C, Viveiros M.

J Med Microbiol. 2018 Jun;67(6):740-749. doi: 10.1099/jmm.0.000741. Epub 2018 May 2.

PMID:
29717972
11.

Analyzing complement activity in the serum and body homogenates of different fish species, using rabbit and sheep red blood cells.

Nayak S, Portugal I, Zilberg D.

Vet Immunol Immunopathol. 2018 May;199:39-42. doi: 10.1016/j.vetimm.2018.03.008. Epub 2018 Mar 22.

PMID:
29678228
12.

Author Correction: Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis.

Coll F, Phelan J, Hill-Cawthorne GA, Nair MB, Mallard K, Ali S, Abdallah AM, Alghamdi S, Alsomali M, Ahmed AO, Portelli S, Oppong Y, Alves A, Bessa TB, Campino S, Caws M, Chatterjee A, Crampin AC, Dheda K, Furnham N, Glynn JR, Grandjean L, Ha DM, Hasan R, Hasan Z, Hibberd ML, Joloba M, Jones-López EC, Matsumoto T, Miranda A, Moore DJ, Mocillo N, Panaiotov S, Parkhill J, Penha C, Perdigão J, Portugal I, Rchiad Z, Robledo J, Sheen P, Shesha NT, Sirgel FA, Sola C, Sousa EO, Streicher EM, Van Helden P, Viveiros M, Warren RM, McNerney R, Pain A, Clark TG.

Nat Genet. 2018 May;50(5):764. doi: 10.1038/s41588-018-0074-3.

PMID:
29674744
13.

Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries.

Perdigão J, Silva C, Diniz J, Pereira C, Machado D, Ramos J, Silva H, Abilleira F, Brum C, Reis AJ, Macedo M, Scaini JL, Silva AB, Esteves L, Macedo R, Maltez F, Clemente S, Coelho E, Viegas S, Rabna P, Rodrigues A, Taveira N, Jordao L, Kritski A, Lapa E Silva JR, Mokrousov I, Couvin D, Rastogi N, Couto I, Pain A, McNerney R, Clark TG, von Groll A, Dalla-Costa ER, Rossetti ML, Silva PEA, Viveiros M, Portugal I.

Infect Genet Evol. 2019 Aug;72:44-58. doi: 10.1016/j.meegid.2018.03.011. Epub 2018 Mar 17.

14.

Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains.

Machado D, Perdigão J, Portugal I, Pieroni M, Silva PA, Couto I, Viveiros M.

Antibiotics (Basel). 2018 Mar 3;7(1). pii: E18. doi: 10.3390/antibiotics7010018.

15.

Complete dorsal pancreatic agenesis and unilateral renal agenesis.

Moreira A, Carvalho A, Portugal I, Jesus JM.

Radiol Case Rep. 2017 Dec 1;13(1):68-71. doi: 10.1016/j.radcr.2017.10.025. eCollection 2018 Feb.

16.

Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis.

Coll F, Phelan J, Hill-Cawthorne GA, Nair MB, Mallard K, Ali S, Abdallah AM, Alghamdi S, Alsomali M, Ahmed AO, Portelli S, Oppong Y, Alves A, Bessa TB, Campino S, Caws M, Chatterjee A, Crampin AC, Dheda K, Furnham N, Glynn JR, Grandjean L, Minh Ha D, Hasan R, Hasan Z, Hibberd ML, Joloba M, Jones-López EC, Matsumoto T, Miranda A, Moore DJ, Mocillo N, Panaiotov S, Parkhill J, Penha C, Perdigão J, Portugal I, Rchiad Z, Robledo J, Sheen P, Shesha NT, Sirgel FA, Sola C, Oliveira Sousa E, Streicher EM, Helden PV, Viveiros M, Warren RM, McNerney R, Pain A, Clark TG.

Nat Genet. 2018 Feb;50(2):307-316. doi: 10.1038/s41588-017-0029-0. Epub 2018 Jan 22. Erratum in: Nat Genet. 2018 Apr 19;:.

17.

Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally.

Phelan J, de Sessions PF, Tientcheu L, Perdigao J, Machado D, Hasan R, Hasan Z, Bergval IL, Anthony R, McNerney R, Antonio M, Portugal I, Viveiros M, Campino S, Hibberd ML, Clark TG.

Sci Rep. 2018 Jan 9;8(1):160. doi: 10.1038/s41598-017-18188-y.

18.

Synthesis of Novel Fluorene Bisamide Derivatives via Ugi Reaction and Evaluation their Biological Activity against Mycobacterium species.

Rezayan AH, Hariri S, Azerang P, Ghavami G, Portugal I, Sardari S.

Iran J Pharm Res. 2017 Spring;16(2):745-755.

19.

Role of Alanine Racemase Mutations in Mycobacterium tuberculosis d-Cycloserine Resistance.

Nakatani Y, Opel-Reading HK, Merker M, Machado D, Andres S, Kumar SS, Moradigaravand D, Coll F, Perdigão J, Portugal I, Schön T, Nair D, Devi KRU, Kohl TA, Beckert P, Clark TG, Maphalala G, Khumalo D, Diel R, Klaos K, Aung HL, Cook GM, Parkhill J, Peacock SJ, Swaminathan S, Viveiros M, Niemann S, Krause KL, Köser CU.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01575-17. doi: 10.1128/AAC.01575-17. Print 2017 Dec.

20.

[Multidrug-Resistant Tuberculosis by Strains of Beijing Family, in Patients from Lisbon, Portugal: Preliminary Report].

Maltez F, Martins T, Póvoas D, Cabo J, Peres H, Antunes F, Perdigão J, Portugal I.

Acta Med Port. 2017 Mar 31;30(3):175-184. doi: 10.20344/amp.7882. Epub 2017 Mar 31. Portuguese.

21.

Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis.

Machado D, Coelho TS, Perdigão J, Pereira C, Couto I, Portugal I, Maschmann RA, Ramos DF, von Groll A, Rossetti MLR, Silva PA, Viveiros M.

Front Microbiol. 2017 Apr 27;8:711. doi: 10.3389/fmicb.2017.00711. eCollection 2017.

22.

Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola.

Perdigão J, Clemente S, Ramos J, Masakidi P, Machado D, Silva C, Couto I, Viveiros M, Taveira N, Portugal I.

Sci Rep. 2017 Feb 23;7:42814. doi: 10.1038/srep42814.

23.

Genetic diversity, transmission dynamics, and drug resistance of Mycobacterium tuberculosis in Luanda, Angola.

Perdigão J, Clemente S, Ramos J, Masakidi P, Machado D, Silva C, Couto I, Viveiros M, Taveira N, Portugal I.

Int J Mycobacteriol. 2016 Dec;5 Suppl 1:S38-S39. doi: 10.1016/j.ijmyco.2016.09.050. Epub 2016 Nov 12.

24.

Beyond extensively drug-resistant tuberculosis in Lisbon, Portugal: a case of linezolid resistance acquisition presenting as an iliopsoas abscess.

Perdigão J, Maltez F, Machado D, Silva H, Pereira C, Silva C, Couto I, Viveiros M, Portugal I.

Int J Antimicrob Agents. 2016 Nov;48(5):569-570. doi: 10.1016/j.ijantimicag.2016.07.026. Epub 2016 Sep 29. No abstract available.

PMID:
27769708
25.

Influence of Polyphosphoric Acid on the Consistency and Composition of Formulated Bitumen: Standard Characterization and NMR Insights.

Varanda C, Portugal I, Ribeiro J, Silva AM, Silva CM.

J Anal Methods Chem. 2016;2016:2915467. doi: 10.1155/2016/2915467. Epub 2016 Aug 8.

26.

Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages.

Phelan JE, Coll F, Bergval I, Anthony RM, Warren R, Sampson SL, Gey van Pittius NC, Glynn JR, Crampin AC, Alves A, Bessa TB, Campino S, Dheda K, Grandjean L, Hasan R, Hasan Z, Miranda A, Moore D, Panaiotov S, Perdigao J, Portugal I, Sheen P, de Oliveira Sousa E, Streicher EM, van Helden PD, Viveiros M, Hibberd ML, Pain A, McNerney R, Clark TG.

BMC Genomics. 2016 Feb 29;17:151. doi: 10.1186/s12864-016-2467-y.

27.

Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis.

Machado D, Pires D, Perdigão J, Couto I, Portugal I, Martins M, Amaral L, Anes E, Viveiros M.

PLoS One. 2016 Feb 26;11(2):e0149326. doi: 10.1371/journal.pone.0149326. eCollection 2016.

28.

Fragment-Based De Novo Design of Antimycobacterial Agents and In Vitro Potency Evaluation.

Sardari S, Portugal I, ALKafri A, Moradi D, Ghavami G.

Comb Chem High Throughput Screen. 2016;19(3):238-45.

PMID:
26892505
29.

High Pressure Laminates with Antimicrobial Properties.

Magina S, Santos MD, Ferra J, Cruz P, Portugal I, Evtuguin D.

Materials (Basel). 2016 Feb 6;9(2). pii: E100. doi: 10.3390/ma9020100.

30.

Multidrug-Resistant Mycobacterium tuberculosis of the Latin American Mediterranean Lineage, Wrongly Identified as Mycobacterium pinnipedii (Spoligotype International Type 863 [SIT863]), Causing Active Tuberculosis in South Brazil.

Dalla Costa ER, Vasconcelos SE, Esteves LS, Gomes HM, Gomes LL, da Silva PA, Perdigão J, Portugal I, Viveiros M, McNerney R, Pain A, Clark TG, Rastogi N, Unis G, Rossetti ML, Suffys PN.

J Clin Microbiol. 2015 Dec;53(12):3805-11.

31.

Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences.

Coll F, McNerney R, Preston MD, Guerra-Assunção JA, Warry A, Hill-Cawthorne G, Mallard K, Nair M, Miranda A, Alves A, Perdigão J, Viveiros M, Portugal I, Hasan Z, Hasan R, Glynn JR, Martin N, Pain A, Clark TG.

Genome Med. 2015 May 27;7(1):51. doi: 10.1186/s13073-015-0164-0. eCollection 2015.

32.

Direct Detection by the Xpert MTB/RIF Assay and Characterization of Multi and Poly Drug-Resistant Tuberculosis in Guinea-Bissau, West Africa.

Rabna P, Ramos J, Ponce G, Sanca L, Mané M, Armada A, Machado D, Vieira F, Gomes VF, Martins E, Colombatti R, Riccardi F, Perdigão J, Sotero J, Portugal I, Couto I, Atouguia J, Rodrigues A, Viveiros M.

PLoS One. 2015 May 27;10(5):e0127536. doi: 10.1371/journal.pone.0127536. eCollection 2015.

33.

Distribution of saphenous vein valves and its practical importance.

Portugal IB, Ribeiro Ide L, Sousa-Rodrigues CF, Monte-Bispo RF, Rocha AC.

Rev Bras Cir Cardiovasc. 2014 Oct-Dec;29(4):564-8. doi: 10.5935/1678-9741.20140038.

34.

Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting.

Perdigão J, Silva H, Machado D, Macedo R, Maltez F, Silva C, Jordao L, Couto I, Mallard K, Coll F, Hill-Cawthorne GA, McNerney R, Pain A, Clark TG, Viveiros M, Portugal I.

BMC Genomics. 2014 Nov 18;15:991. doi: 10.1186/1471-2164-15-991.

35.

Mycobacterial interspersed repetitive unit typing and mutational profile for multidrug-resistant and extensively drug-resistant tuberculosis surveillance in Portugal: a 3-year period overview.

Silva C, Perdigão J, Jordão L, Portugal I.

Int J Antimicrob Agents. 2014 Dec;44(6):546-51. doi: 10.1016/j.ijantimicag.2014.06.021. Epub 2014 Sep 6.

PMID:
25270633
36.

A robust SNP barcode for typing Mycobacterium tuberculosis complex strains.

Coll F, McNerney R, Guerra-Assunção JA, Glynn JR, Perdigão J, Viveiros M, Portugal I, Pain A, Martin N, Clark TG.

Nat Commun. 2014 Sep 1;5:4812. doi: 10.1038/ncomms5812.

37.

PolyTB: a genomic variation map for Mycobacterium tuberculosis.

Coll F, Preston M, Guerra-Assunção JA, Hill-Cawthorn G, Harris D, Perdigão J, Viveiros M, Portugal I, Drobniewski F, Gagneux S, Glynn JR, Pain A, Parkhill J, McNerney R, Martin N, Clark TG.

Tuberculosis (Edinb). 2014 May;94(3):346-54. doi: 10.1016/j.tube.2014.02.005. Epub 2014 Feb 15.

38.

Pre-multidrug-resistant Mycobacterium tuberculosis Beijing strain associated with disseminated tuberculosis in a pet dog.

Botelho A, Perdigão J, Canto A, Albuquerque T, Leal N, Macedo R, Portugal I, Cunha MV.

J Clin Microbiol. 2014 Jan;52(1):354-6. doi: 10.1128/JCM.02800-13. Epub 2013 Oct 23.

39.

GidB mutation as a phylogenetic marker for Q1 cluster Mycobacterium tuberculosis isolates and intermediate-level streptomycin resistance determinant in Lisbon, Portugal.

Perdigão J, Macedo R, Machado D, Silva C, Jordão L, Couto I, Viveiros M, Portugal I.

Clin Microbiol Infect. 2014 May;20(5):O278-84. doi: 10.1111/1469-0691.12392. Epub 2013 Nov 4.

40.

Exploring the contribution of mycobacteria characteristics in their interaction with human macrophages.

Silva C, Perdigao J, Alverca E, de Matos AP, Carvalho PA, Portugal I, Jordao L.

Microsc Microanal. 2013 Oct;19(5):1159-69. doi: 10.1017/S1431927613001906. Epub 2013 Jun 24.

PMID:
23790221
41.

High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations.

Machado D, Perdigão J, Ramos J, Couto I, Portugal I, Ritter C, Boettger EC, Viveiros M.

J Antimicrob Chemother. 2013 Aug;68(8):1728-32. doi: 10.1093/jac/dkt090. Epub 2013 Mar 28.

42.

From multidrug-resistant to extensively drug-resistant tuberculosis in Lisbon, Portugal: the stepwise mode of resistance acquisition.

Perdigão J, Macedo R, Silva C, Machado D, Couto I, Viveiros M, Jordao L, Portugal I.

J Antimicrob Chemother. 2013 Jan;68(1):27-33. doi: 10.1093/jac/dks371. Epub 2012 Oct 10.

PMID:
23054995
43.

Multidrug and extensively drug-resistant tuberculosis in Lisbon and Vale do Tejo, Portugal, from 2008 to 2010.

Macedo R, Antunes AF, Villar M, Portugal I.

Int J Mycobacteriol. 2012 Sep;1(3):131-6. doi: 10.1016/j.ijmyco.2012.07.001. Epub 2012 Aug 13.

44.

Biomass-based polyols through oxypropylation reaction.

Aniceto JP, Portugal I, Silva CM.

ChemSusChem. 2012 Aug;5(8):1358-68. doi: 10.1002/cssc.201200032. Epub 2012 Jul 16. Review.

PMID:
22807440
45.

Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.

Machado D, Couto I, Perdigão J, Rodrigues L, Portugal I, Baptista P, Veigas B, Amaral L, Viveiros M.

PLoS One. 2012;7(4):e34538. doi: 10.1371/journal.pone.0034538. Epub 2012 Apr 6.

46.

Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis.

Veigas B, Machado D, Perdigão J, Portugal I, Couto I, Viveiros M, Baptista PV.

Nanotechnology. 2010 Oct 15;21(41):415101. doi: 10.1088/0957-4484/21/41/415101. Epub 2010 Sep 16.

PMID:
20844324
47.

Tuberculosis drug-resistance in Lisbon, Portugal: a 6-year overview.

Perdigão J, Macedo R, Silva C, Pinto C, Furtado C, Brum L, Portugal I.

Clin Microbiol Infect. 2011 Sep;17(9):1397-402. doi: 10.1111/j.1469-0691.2010.03351.x. Epub 2010 Oct 19.

48.

Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections.

Viveiros M, Martins M, Couto I, Rodrigues L, Machado D, Portugal I, Amaral L.

Expert Rev Anti Infect Ther. 2010 Apr;8(4):465-80. doi: 10.1586/eri.10.20. Review.

PMID:
20377340
49.

Hydration of cellulose/silica hybrids assessed by sorption isotherms.

Portugal I, Dias VM, Duarte RF, Evtuguin DV.

J Phys Chem B. 2010 Mar 25;114(11):4047-55. doi: 10.1021/jp911270y.

PMID:
20196586
50.

Genetic analysis of extensively drug-resistant Mycobacterium tuberculosis strains in Lisbon, Portugal.

Perdigão J, Macedo R, Malaquias A, Ferreira A, Brum L, Portugal I.

J Antimicrob Chemother. 2010 Feb;65(2):224-7. doi: 10.1093/jac/dkp452. Epub 2009 Dec 22.

PMID:
20028780

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