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Items: 1 to 50 of 173

1.

Biofluid quantification of TWEAK/Fn14 axis in combination with a selected biomarker panel improves assessment of prostate cancer aggressiveness.

Ruiz-Plazas X, Rodríguez-Gallego E, Alves M, Altuna-Coy A, Lozano-Bartolomé J, Portero-Otin M, García-Fontgivell JF, Martínez-González S, Segarra J, Chacón MR.

J Transl Med. 2019 Sep 9;17(1):307. doi: 10.1186/s12967-019-2053-6.

2.

A prospective pilot study using metabolomics discloses specific fatty acid, catecholamine and tryptophan metabolic pathways as possible predictors for a negative outcome after severe trauma.

Servià L, Jové M, Sol J, Pamplona R, Badia M, Montserrat N, Portero-Otin M, Trujillano J.

Scand J Trauma Resusc Emerg Med. 2019 May 22;27(1):56. doi: 10.1186/s13049-019-0631-5.

3.

Adipose Tissue Protein Glycoxidation is Associated with Weight-Loss Potential.

Serrano JCE, Baena-Fustegueras JA, Martin-Gari M, Rassendren H, Cassanye A, Naudí A, López-Cano C, Sánchez E, de la Fuente-Juárez MC, Herrerías González F, Olsina Kissler JJ, Lecube A, Portero-Otín M.

Obesity (Silver Spring). 2019 Jul;27(7):1133-1140. doi: 10.1002/oby.22501. Epub 2019 May 21.

4.

Biomarker Identification, Safety, and Efficacy of High-Dose Antioxidants for Adrenomyeloneuropathy: a Phase II Pilot Study.

Casasnovas C, Ruiz M, Schlüter A, Naudí A, Fourcade S, Veciana M, Castañer S, Albertí A, Bargalló N, Johnson M, Raymond GV, Fatemi A, Moser AB, Villarroya F, Portero-Otín M, Artuch R, Pamplona R, Pujol A.

Neurotherapeutics. 2019 May 10. doi: 10.1007/s13311-019-00735-2. [Epub ahead of print]

PMID:
31077039
5.

Altered Dynein Axonemal Assembly Factor 1 Expression in C-Boutons in Bulbar and Spinal Cord Motor-Neurons in Sporadic Amyotrophic Lateral Sclerosis.

Andrés-Benito P, Povedano M, Torres P, Portero-Otín M, Ferrer I.

J Neuropathol Exp Neurol. 2019 May 1;78(5):416-425. doi: 10.1093/jnen/nlz019.

PMID:
30939186
6.

Skin Autofluorescence Measurement in Subclinical Atheromatous Disease: Results from the ILERVAS Project.

Sánchez E, Betriu À, Yeramian A, Fernández E, Purroy F, Sánchez-de-la-Torre M, Pamplona R, Miquel E, Kerkeni M, Hernández C, Simó R, Lecube A; ILERVAS project; ILERVAS Project:, Hernández M, Rius F, Polanco D, Barbé F, Torres G, Suárez G, Portero-Otin M, Jové M, Colàs-Campàs L, Benabdelhak I, Farràs C, Ortega M, Manuel Valdivielso J, Bermúdez-López M, Martínez-Alonso M.

J Atheroscler Thromb. 2019 Mar 6. doi: 10.5551/jat.47498. [Epub ahead of print]

7.

Faecal bacterial and short-chain fatty acids signature in hypercholesterolemia.

Granado-Serrano AB, Martín-Garí M, Sánchez V, Riart Solans M, Berdún R, Ludwig IA, Rubió L, Vilaprinyó E, Portero-Otín M, Serrano JCE.

Sci Rep. 2019 Feb 11;9(1):1772. doi: 10.1038/s41598-019-38874-3.

8.

Adipose TSHB in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence.

Moreno-Navarrete JM, Liñares-Pose L, Sabater M, Rial-Pensado E, Comas F, Jové M, Latorre J, Ortega F, Ricart W, Portero-Otin M, López M, Fernández-Real JM.

Cell Physiol Biochem. 2018;51(1):142-153. doi: 10.1159/000495170. Epub 2018 Nov 16.

9.

Location-dependent effects of trauma on oxidative stress in humans.

Servia L, Serrano JCE, Pamplona R, Badia M, Montserrat N, Portero-Otin M, Trujillano J.

PLoS One. 2018 Oct 11;13(10):e0205519. doi: 10.1371/journal.pone.0205519. eCollection 2018.

10.

Regional vulnerability to lipoxidative damage and inflammation in normal human brain aging.

Domínguez-González M, Puigpinós M, Jové M, Naudi A, Portero-Otín M, Pamplona R, Ferrer I.

Exp Gerontol. 2018 Oct 1;111:218-228. doi: 10.1016/j.exger.2018.07.023. Epub 2018 Aug 2.

PMID:
30077575
11.

Aberrant regulation of the GSK-3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy.

Ranea-Robles P, Launay N, Ruiz M, Calingasan NY, Dumont M, Naudí A, Portero-Otín M, Pamplona R, Ferrer I, Beal MF, Fourcade S, Pujol A.

EMBO Mol Med. 2018 Aug;10(8). pii: e8604. doi: 10.15252/emmm.201708604.

12.

Psoriasis, metabolic syndrome and cardiovascular risk factors. A population-based study.

Fernández-Armenteros JM, Gómez-Arbonés X, Buti-Soler M, Betriu-Bars A, Sanmartin-Novell V, Ortega-Bravo M, Martínez-Alonso M, Garí E, Portero-Otín M, Santamaria-Babi L, Casanova-Seuma JM.

J Eur Acad Dermatol Venereol. 2019 Jan;33(1):128-135. doi: 10.1111/jdv.15159. Epub 2018 Jul 17.

PMID:
29953676
13.

Essential physiological differences characterise short- and long-lived strains of Drosophila melanogaster.

Gubina N, Naudi A, Stefanatos R, Jove M, Scialo F, Fernandez-Ayala DJ, Rantapero T, Yurkevych I, Portero-Otin M, Nykter M, Lushchak O, Navas P, Pamplona R, Sanz A.

J Gerontol A Biol Sci Med Sci. 2018 Jun 26. doi: 10.1093/gerona/gly143. [Epub ahead of print]

PMID:
29945183
14.

Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue.

Torres P, Ramírez-Núñez O, Romero-Guevara R, Barés G, Granado-Serrano AB, Ayala V, Boada J, Fontdevila L, Povedano M, Sanchís D, Pamplona R, Ferrer I, Portero-Otín M.

Autophagy. 2018;14(8):1398-1403. doi: 10.1080/15548627.2018.1474311. Epub 2018 Jul 28.

15.

Subcutaneous advanced glycation end-products and lung function according to glucose abnormalities: The ILERVAS Project.

Sánchez E, Lecube A, Betriu À, Hernández C, López-Cano C, Gutiérrez-Carrasquilla L, Kerkeni M, Yeramian A, Purroy F, Pamplona R, Farràs C, Fernández E, Barbé F, Simó R; ILERVAS project, Hernández M, Rius F, Polanco D, de la Torre MS, Torres G, Godoy P, Portero-Otin M, Jové M, Colàs-Compàs L, Benabdelhak I, Miquel E, Ortega M, Valdivielso JM, Bermúdez M, Martínez-Alonso M.

Diabetes Metab. 2018 Apr 13. pii: S1262-3636(18)30079-X. doi: 10.1016/j.diabet.2018.04.002. [Epub ahead of print] No abstract available.

PMID:
29706471
16.

Lipidomics reveals altered biosynthetic pathways of glycerophospholipids and cell signaling as biomarkers of the polycystic ovary syndrome.

Jové M, Pradas I, Naudí A, Rovira-Llopis S, Bañuls C, Rocha M, Portero-Otin M, Hernández-Mijares A, Victor VM, Pamplona R.

Oncotarget. 2017 Dec 17;9(4):4522-4536. doi: 10.18632/oncotarget.23393. eCollection 2018 Jan 12.

17.

Altered Expression of miR-181a-5p and miR-23a-3p Is Associated With Obesity and TNFα-Induced Insulin Resistance.

Lozano-Bartolomé J, Llauradó G, Portero-Otin M, Altuna-Coy A, Rojo-Martínez G, Vendrell J, Jorba R, Rodríguez-Gallego E, Chacón MR.

J Clin Endocrinol Metab. 2018 Apr 1;103(4):1447-1458. doi: 10.1210/jc.2017-01909.

PMID:
29409019
18.

Tumour-microenvironmental blood flow determines a metabolomic signature identifying lysophospholipids and resolvin D as biomarkers in endometrial cancer patients.

Eritja N, Jové M, Fasmer KE, Gatius S, Portero-Otin M, Trovik J, Krakstad C, Sol J, Pamplona R, Haldorsen IS, Matias-Guiu X.

Oncotarget. 2017 Nov 20;8(65):109018-109026. doi: 10.18632/oncotarget.22558. eCollection 2017 Dec 12.

19.

Metabolomic Estimation of the Diagnosis and Onset Time of Permanent and Transient Cerebral Ischemia.

Cambray S, Portero-Otin M, Jové M, Torreguitart N, Colàs-Campàs L, Sanz A, Benabdelhak I, Yemisci M, Dalkara T, Dönmez-Demir B, Egea J, Purroy F.

Mol Neurobiol. 2018 Jul;55(7):6193-6200. doi: 10.1007/s12035-017-0827-5. Epub 2017 Dec 21.

PMID:
29270918
20.

The gut mycobiome composition is linked to carotid atherosclerosis.

Chacón MR, Lozano-Bartolomé J, Portero-Otín M, Rodríguez MM, Xifra G, Puig J, Blasco G, Ricart W, Chaves FJ, Fernández-Real JM.

Benef Microbes. 2018 Feb 27;9(2):185-198. doi: 10.3920/BM2017.0029. Epub 2017 Nov 10.

PMID:
29124969
21.

Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance.

Fourcade S, Morató L, Parameswaran J, Ruiz M, Ruiz-Cortés T, Jové M, Naudí A, Martínez-Redondo P, Dierssen M, Ferrer I, Villarroya F, Pamplona R, Vaquero A, Portero-Otín M, Pujol A.

Aging Cell. 2017 Dec;16(6):1404-1413. doi: 10.1111/acel.12682. Epub 2017 Oct 5.

22.

Lipid Profile in Human Frontal Cortex Is Sustained Throughout Healthy Adult Life Span to Decay at Advanced Ages.

Cabré R, Naudí A, Dominguez-Gonzalez M, Jové M, Ayala V, Mota-Martorell N, Pradas I, Nogueras L, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

J Gerontol A Biol Sci Med Sci. 2018 May 9;73(6):703-710. doi: 10.1093/gerona/glx164.

PMID:
28958038
23.

Characterization of the post-prandial insulinemic response and low glycaemic index of a soy beverage.

Serrano JC, Martín-Gari M, Cassanye A, Granado-Serrano AB, Portero-Otín M.

PLoS One. 2017 Aug 9;12(8):e0182762. doi: 10.1371/journal.pone.0182762. eCollection 2017.

24.

Differential metabolic profiles associated to movement behaviour of stream-resident brown trout (Salmo trutta).

Oromi N, Jové M, Pascual-Pons M, Royo JL, Rocaspana R, Aparicio E, Pamplona R, Palau A, Sanuy D, Fibla J, Portero-Otin M.

PLoS One. 2017 Jul 27;12(7):e0181697. doi: 10.1371/journal.pone.0181697. eCollection 2017.

25.

TSHB mRNA is linked to cholesterol metabolism in adipose tissue.

Moreno-Navarrete JM, Moreno M, Ortega F, Xifra G, Hong S, Asara JM, Serrano JCE, Jové M, Pissios P, Blüher M, Ricart W, Portero-Otin M, Fernández-Real JM.

FASEB J. 2017 Oct;31(10):4482-4491. doi: 10.1096/fj.201700161R. Epub 2017 Jun 23.

26.

The Gut Metagenome Changes in Parallel to Waist Circumference, Brain Iron Deposition, and Cognitive Function.

Blasco G, Moreno-Navarrete JM, Rivero M, Pérez-Brocal V, Garre-Olmo J, Puig J, Daunis-I-Estadella P, Biarnés C, Gich J, Fernández-Aranda F, Alberich-Bayarri Á, Moya A, Pedraza S, Ricart W, López M, Portero-Otin M, Fernandez-Real JM.

J Clin Endocrinol Metab. 2017 Aug 1;102(8):2962-2973. doi: 10.1210/jc.2017-00133.

PMID:
28591831
27.

Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system.

Naudí A, Cabré R, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):485-495. doi: 10.1016/j.bbalip.2017.02.001. Epub 2017 Feb 7.

PMID:
28185952
28.

Biofortification of crops with nutrients: factors affecting utilization and storage.

Díaz-Gómez J, Twyman RM, Zhu C, Farré G, Serrano JC, Portero-Otin M, Muñoz P, Sandmann G, Capell T, Christou P.

Curr Opin Biotechnol. 2017 Apr;44:115-123. doi: 10.1016/j.copbio.2016.12.002. Epub 2017 Jan 6. Review.

PMID:
28068552
29.

Specific Metabolomics Adaptations Define a Differential Regional Vulnerability in the Adult Human Cerebral Cortex.

Cabré R, Jové M, Naudí A, Ayala V, Piñol-Ripoll G, Gil-Villar MP, Dominguez-Gonzalez M, Obis È, Berdun R, Mota-Martorell N, Portero-Otin M, Ferrer I, Pamplona R.

Front Mol Neurosci. 2016 Dec 8;9:138. doi: 10.3389/fnmol.2016.00138. eCollection 2016.

30.

Adipocyte lipopolysaccharide binding protein (LBP) is linked to a specific lipidomic signature.

Moreno-Navarrete JM, Jové M, Padró T, Boada J, Ortega F, Ricart W, Pamplona R, Badimón L, Portero-Otín M, Fernández-Real JM.

Obesity (Silver Spring). 2017 Feb;25(2):391-400. doi: 10.1002/oby.21711. Epub 2016 Dec 21.

31.

Sixty years old is the breakpoint of human frontal cortex aging.

Cabré R, Naudí A, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

Free Radic Biol Med. 2017 Feb;103:14-22. doi: 10.1016/j.freeradbiomed.2016.12.010. Epub 2016 Dec 13.

PMID:
27979658
32.

Metabolomics Predicts Neuroimaging Characteristics of Transient Ischemic Attack Patients.

Purroy F, Cambray S, Mauri-Capdevila G, Jové M, Sanahuja J, Farré J, Benabdelhak I, Molina-Seguin J, Colàs-Campàs L, Begue R, Gil MI, Pamplona R, Portero-Otín M.

EBioMedicine. 2016 Dec;14:131-138. doi: 10.1016/j.ebiom.2016.11.010. Epub 2016 Nov 9.

33.

The distribution of carotenoids in hens fed on biofortified maize is influenced by feed composition, absorption, resource allocation and storage.

Moreno JA, Díaz-Gómez J, Nogareda C, Angulo E, Sandmann G, Portero-Otin M, Serrano JC, Twyman RM, Capell T, Zhu C, Christou P.

Sci Rep. 2016 Oct 14;6:35346. doi: 10.1038/srep35346.

34.

Metabotyping human endometrioid endometrial adenocarcinoma reveals an implication of endocannabinoid metabolism.

Jové M, Gatius S, Yeramian A, Portero-Otin M, Eritja N, Santacana M, Colas E, Ruiz M, Pamplona R, Matias-Guiu X.

Oncotarget. 2016 Aug 9;7(32):52364-52374. doi: 10.18632/oncotarget.10564.

35.

A Stress-Resistant Lipidomic Signature Confers Extreme Longevity to Humans.

Jové M, Naudí A, Gambini J, Borras C, Cabré R, Portero-Otín M, Viña J, Pamplona R.

J Gerontol A Biol Sci Med Sci. 2017 Jan;72(1):30-37. Epub 2016 Mar 24.

PMID:
27013396
36.

Effect of Dietary Bioactive Compounds on Mitochondrial and Metabolic Flexibility.

Serrano JCE, Cassanye A, Martín-Gari M, Granado-Serrano AB, Portero-Otín M.

Diseases. 2016 Mar 10;4(1). pii: E14. doi: 10.3390/diseases4010014. Review.

37.

Erratum: Obesity changes the human gut mycobiome.

Mar Rodríguez M, Pérez D, Javier Chaves F, Esteve E, Marin-Garcia P, Xifra G, Vendrell J, Jové M, Pamplona R, Ricart W, Portero-Otin M, Chacón MR, Fernández Real JM.

Sci Rep. 2016 Feb 24;6:21679. doi: 10.1038/srep21679. No abstract available.

38.

Targeted activation of CREB in reactive astrocytes is neuroprotective in focal acute cortical injury.

Pardo L, Schlüter A, Valor LM, Barco A, Giralt M, Golbano A, Hidalgo J, Jia P, Zhao Z, Jové M, Portero-Otin M, Ruiz M, Giménez-Llort L, Masgrau R, Pujol A, Galea E.

Glia. 2016 May;64(5):853-74. doi: 10.1002/glia.22969. Epub 2016 Feb 16.

PMID:
26880229
39.

Metabolomics uncovers the role of adipose tissue PDXK in adipogenesis and systemic insulin sensitivity.

Moreno-Navarrete JM, Jove M, Ortega F, Xifra G, Ricart W, Obis È, Pamplona R, Portero-Otin M, Fernández-Real JM.

Diabetologia. 2016 Apr;59(4):822-32. doi: 10.1007/s00125-016-3863-1. Epub 2016 Feb 2.

PMID:
26831303
40.

Oral intake of genetically engineered high-carotenoid corn ameliorates hepatomegaly and hepatic steatosis in PTEN haploinsufficient mice.

Eritja N, Arjó G, Santacana M, Gatius S, Ramírez-Núñez O, Arcal L, Serrano JCE, Pamplona R, Dolcet X, Piñol C, Christou P, Matias-Guiu X, Portero-Otin M.

Biochim Biophys Acta. 2016 Apr;1862(4):526-535. doi: 10.1016/j.bbadis.2016.01.018. Epub 2016 Jan 26.

41.

Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis.

Cacabelos D, Ayala V, Granado-Serrano AB, Jové M, Torres P, Boada J, Cabré R, Ramírez-Núñez O, Gonzalo H, Soler-Cantero A, Serrano JC, Bellmunt MJ, Romero MP, Motilva MJ, Nonaka T, Hasegawa M, Ferrer I, Pamplona R, Portero-Otín M.

Neurobiol Dis. 2016 Apr;88:148-60. doi: 10.1016/j.nbd.2016.01.007. Epub 2016 Jan 12.

PMID:
26805387
42.

Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS.

Cacabelos D, Ramírez-Núñez O, Granado-Serrano AB, Torres P, Ayala V, Moiseeva V, Povedano M, Ferrer I, Pamplona R, Portero-Otin M, Boada J.

Acta Neuropathol Commun. 2016 Jan 13;4:3. doi: 10.1186/s40478-015-0271-6.

43.

Obesity changes the human gut mycobiome.

Mar Rodríguez M, Pérez D, Javier Chaves F, Esteve E, Marin-Garcia P, Xifra G, Vendrell J, Jové M, Pamplona R, Ricart W, Portero-Otin M, Chacón MR, Fernández Real JM.

Sci Rep. 2015 Oct 12;5:14600. doi: 10.1038/srep14600. Erratum in: Sci Rep. 2016;6:21679.

44.

Gut Microbiota Interacts With Brain Microstructure and Function.

Fernandez-Real JM, Serino M, Blasco G, Puig J, Daunis-i-Estadella J, Ricart W, Burcelin R, Fernández-Aranda F, Portero-Otin M.

J Clin Endocrinol Metab. 2015 Dec;100(12):4505-13. doi: 10.1210/jc.2015-3076. Epub 2015 Oct 7.

PMID:
26445114
45.

Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy.

Ruiz M, Jové M, Schlüter A, Casasnovas C, Villarroya F, Guilera C, Ortega FJ, Naudí A, Pamplona R, Gimeno R, Fourcade S, Portero-Otín M, Pujol A.

Hum Mol Genet. 2015 Dec 15;24(24):6861-76. doi: 10.1093/hmg/ddv375. Epub 2015 Sep 14.

PMID:
26370417
46.

Neuroinflammatory Gene Regulation, Mitochondrial Function, Oxidative Stress, and Brain Lipid Modifications With Disease Progression in Tau P301S Transgenic Mice as a Model of Frontotemporal Lobar Degeneration-Tau.

López-González I, Aso E, Carmona M, Armand-Ugon M, Blanco R, Naudí A, Cabré R, Portero-Otin M, Pamplona R, Ferrer I.

J Neuropathol Exp Neurol. 2015 Oct;74(10):975-99. doi: 10.1097/NEN.0000000000000241.

PMID:
26360374
47.

Lipidomics of human brain aging and Alzheimer's disease pathology.

Naudí A, Cabré R, Jové M, Ayala V, Gonzalo H, Portero-Otín M, Ferrer I, Pamplona R.

Int Rev Neurobiol. 2015;122:133-89. doi: 10.1016/bs.irn.2015.05.008. Epub 2015 Jun 19. Review.

PMID:
26358893
48.

Nutridynamics: mechanism(s) of action of bioactive compounds and their effects.

Serrano JC, Jove M, Gonzalo H, Pamplona R, Portero-Otin M.

Int J Food Sci Nutr. 2015 Jul;66 Suppl 1:S22-30. Review.

PMID:
26241008
49.

Dietary advanced glycation end products and their role in health and disease.

Uribarri J, del Castillo MD, de la Maza MP, Filip R, Gugliucci A, Luevano-Contreras C, Macías-Cervantes MH, Markowicz Bastos DH, Medrano A, Menini T, Portero-Otin M, Rojas A, Sampaio GR, Wrobel K, Wrobel K, Garay-Sevilla ME.

Adv Nutr. 2015 Jul 15;6(4):461-73. doi: 10.3945/an.115.008433. Print 2015 Jul. Review.

50.

Human Aging Is a Metabolome-related Matter of Gender.

Jové M, Maté I, Naudí A, Mota-Martorell N, Portero-Otín M, De la Fuente M, Pamplona R.

J Gerontol A Biol Sci Med Sci. 2016 May;71(5):578-85. doi: 10.1093/gerona/glv074. Epub 2015 May 26.

PMID:
26019184

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