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Items: 1 to 50 of 137

1.

5-Formylcytosine organizes nucleosomes and forms Schiff base interactions with histones in mouse embryonic stem cells.

Raiber EA, Portella G, Martínez Cuesta S, Hardisty R, Murat P, Li Z, Iurlaro M, Dean W, Spindel J, Beraldi D, Liu Z, Dawson MA, Reik W, Balasubramanian S.

Nat Chem. 2018 Dec;10(12):1258-1266. doi: 10.1038/s41557-018-0149-x. Epub 2018 Oct 22.

PMID:
30349137
2.

Intensive care support and clinical outcomes of patients with Ebola virus disease (EVD) in West Africa.

Langer M, Portella G, Finazzi S, Chatenoud L, Lanini S, Vairo F, Fowler R, Miccio R, Ippolito G, Bertolini G, Strada G.

Intensive Care Med. 2018 Aug;44(8):1266-1275. doi: 10.1007/s00134-018-5308-4. Epub 2018 Jul 30.

3.

Retraction for Fusco et al., "A mos Oncogene-Containing Retrovirus, Myeloproliferative Sarcoma Virus, Transforms Rat Thyroid Epithelial Cells and Irreversibly Blocks Their Differentiation Pattern".

Fusco A, Portella G, Di Fiore PP, Berlingieri MT, Di Lauro R, Schneider AB, Vecchio G.

J Virol. 2018 Feb 26;92(6). pii: e02169-17. doi: 10.1128/JVI.02169-17. eCollection 2018 Mar 15.

4.

Reply to Reisler et al.

Lanini S, Portella G, Vairo F, Di Caro A, Kobinger G, Zumla A, Ippolito G.

Clin Infect Dis. 2018 Apr 17;66(9):1480-1481. doi: 10.1093/cid/cix1026. No abstract available.

PMID:
29272344
5.

Relationship Between Viremia and Specific Organ Damage in Ebola Patients: A Cohort Study.

Lanini S, Portella G, Vairo F, Kobinger GP, Pesenti A, Langer M, Kabia S, Brogiato G, Amone J, Castilletti C, Miccio R, Capobianchi MR, Strada G, Zumla A, Di Caro A, Ippolito G; INMI-EMERGENCY EBOV Sierra Leone Study Group .

Clin Infect Dis. 2018 Jan 6;66(1):36-44. doi: 10.1093/cid/cix704.

PMID:
29020340
6.

The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage.

Kitevski-LeBlanc J, Fradet-Turcotte A, Kukic P, Wilson MD, Portella G, Yuwen T, Panier S, Duan S, Canny MD, van Ingen H, Arrowsmith CH, Rubinstein JL, Vendruscolo M, Durocher D, Kay LE.

Elife. 2017 Apr 13;6. pii: e23872. doi: 10.7554/eLife.23872.

7.

Lipopolysaccharide-Elicited TSLPR Expression Enriches a Functionally Discrete Subset of Human CD14+ CD1c+ Monocytes.

Borriello F, Iannone R, Di Somma S, Vastolo V, Petrosino G, Visconte F, Raia M, Scalia G, Loffredo S, Varricchi G, Galdiero MR, Granata F, Del Vecchio L, Portella G, Marone G.

J Immunol. 2017 May 1;198(9):3426-3435. doi: 10.4049/jimmunol.1601497. Epub 2017 Mar 24.

8.

Evaluation of the Automated QIAsymphony SP/AS Workflow for Cytomegalovirus DNA Extraction and Amplification from Dried Blood Spots.

Spalletti-Cernia D, Barbato S, Sorrentino R, Vallefuoco L, Rocco C, Di Costanzo P, Giannattasio A, Raimondi F, Mazzarella C, De Mattia R, Portella G.

Intervirology. 2016;59(4):211-216. doi: 10.1159/000457953. Epub 2017 Mar 10.

9.

Selenium supplementation modulates apoptotic processes in thyroid follicular cells.

Nettore IC, De Nisco E, Desiderio S, Passaro C, Maione L, Negri M, Albano L, Pivonello R, Pivonello C, Portella G, Ungaro P, Colao A, Macchia PE.

Biofactors. 2017 May 6;43(3):415-423. doi: 10.1002/biof.1351. Epub 2017 Mar 2.

PMID:
28251705
10.

GM-CSF and IL-3 Modulate Human Monocyte TNF-α Production and Renewal in In Vitro Models of Trained Immunity.

Borriello F, Iannone R, Di Somma S, Loffredo S, Scamardella E, Galdiero MR, Varricchi G, Granata F, Portella G, Marone G.

Front Immunol. 2017 Jan 16;7:680. doi: 10.3389/fimmu.2016.00680. eCollection 2016.

11.

How accurate are accurate force-fields for B-DNA?

Dans PD, Ivani I, Hospital A, Portella G, González C, Orozco M.

Nucleic Acids Res. 2017 Apr 20;45(7):4217-4230. doi: 10.1093/nar/gkw1355.

12.

Ebola virus disease and critical illness.

Leligdowicz A, Fischer WA 2nd, Uyeki TM, Fletcher TE, Adhikari NK, Portella G, Lamontagne F, Clement C, Jacob ST, Rubinson L, Vanderschuren A, Hajek J, Murthy S, Ferri M, Crozier I, Ibrahima E, Lamah MC, Schieffelin JS, Brett-Major D, Bausch DG, Shindo N, Chan AK, O'Dempsey T, Mishra S, Jacobs M, Dickson S, Lyon GM 3rd, Fowler RA.

Crit Care. 2016 Jul 29;20(1):217. doi: 10.1186/s13054-016-1325-2. Review.

13.

Fourth generation assays for HIV testing.

Vallefuoco L, Mazzarella C, Portella G.

Expert Rev Mol Diagn. 2016 Jul;16(7):723-32. doi: 10.1080/14737159.2016.1179115. Epub 2016 May 6. Review.

PMID:
27095565
14.

Non-randomised Ebola trials--lessons for optimal outbreak research.

Ippolito G, Lanini S, Brouqui P, Di Caro A, Vairo F, Fusco FM, Krishna S, Capobianchi MR, Kyobe-Bosa H, Puro V, Wölfel R, Avsic-Zupanc T, Ioannidis JP, Portella G, Kremsner P, Dar O, Bates M, Zumla A.

Lancet Infect Dis. 2016 Apr;16(4):407-8. doi: 10.1016/S1473-3099(16)00132-8. No abstract available.

PMID:
27036341
15.

The oncolytic virus dl922-947 reduces IL-8/CXCL8 and MCP-1/CCL2 expression and impairs angiogenesis and macrophage infiltration in anaplastic thyroid carcinoma.

Passaro C, Borriello F, Vastolo V, Di Somma S, Scamardella E, Gigantino V, Franco R, Marone G, Portella G.

Oncotarget. 2016 Jan 12;7(2):1500-15. doi: 10.18632/oncotarget.6430.

16.

Parmbsc1: a refined force field for DNA simulations.

Ivani I, Dans PD, Noy A, Pérez A, Faustino I, Hospital A, Walther J, Andrio P, Goñi R, Balaceanu A, Portella G, Battistini F, Gelpí JL, González C, Vendruscolo M, Laughton CA, Harris SA, Case DA, Orozco M.

Nat Methods. 2016 Jan;13(1):55-8. doi: 10.1038/nmeth.3658. Epub 2015 Nov 16.

17.

Blood kinetics of Ebola virus in survivors and nonsurvivors.

Lanini S, Portella G, Vairo F, Kobinger GP, Pesenti A, Langer M, Kabia S, Brogiato G, Amone J, Castilletti C, Miccio R, Zumla A, Capobianchi MR, Di Caro A, Strada G, Ippolito G; INMI-EMERGENCY EBOV Sierra Leone Study Group.

J Clin Invest. 2015 Dec;125(12):4692-8. doi: 10.1172/JCI83111. Epub 2015 Nov 9.

18.

Seven-Membered Ring Nucleoside Analogues: Stereoselective Synthesis and Studies on Their Conformational Properties.

Habibian M, Martínez-Montero S, Portella G, Chua Z, Bohle DS, Orozco M, Damha MJ.

Org Lett. 2015 Nov 6;17(21):5416-9. doi: 10.1021/acs.orglett.5b02769. Epub 2015 Oct 22.

PMID:
26492193
19.

Molecular Signature of the Ebola Virus Associated with the Fishermen Community Outbreak in Aberdeen, Sierra Leone, in February 2015.

Capobianchi MR, Gruber CE, Carletti F, Meschi S, Castilletti C, Vairo F, Biava M, Minosse C, Strada G, Portella G, Miccio R, Minardi V, Rolla L, Kamara A, Chillemi G, Desideri A, Di Caro A, Ippolito G.

Genome Announc. 2015 Sep 24;3(5). pii: e01093-15. doi: 10.1128/genomeA.01093-15.

20.

Can A Denaturant Stabilize DNA? Pyridine Reverses DNA Denaturation in Acidic pH.

Portella G, Terrazas M, Villegas N, González C, Orozco M.

Angew Chem Int Ed Engl. 2015 Sep 1;54(36):10488-91. doi: 10.1002/anie.201503770. Epub 2015 Jul 24.

PMID:
26224143
21.

Chromatin Unfolding by Epigenetic Modifications Explained by Dramatic Impairment of Internucleosome Interactions: A Multiscale Computational Study.

Collepardo-Guevara R, Portella G, Vendruscolo M, Frenkel D, Schlick T, Orozco M.

J Am Chem Soc. 2015 Aug 19;137(32):10205-15. doi: 10.1021/jacs.5b04086. Epub 2015 Aug 10.

22.

Are adaptive randomised trials or non-randomised studies the best way to address the Ebola outbreak in west Africa?

Lanini S, Zumla A, Ioannidis JP, Di Caro A, Krishna S, Gostin L, Girardi E, Pletschette M, Strada G, Baritussio A, Portella G, Apolone G, Cavuto S, Satolli R, Kremsner P, Vairo F, Ippolito G.

Lancet Infect Dis. 2015 Jun;15(6):738-45. doi: 10.1016/S1473-3099(15)70106-4. Epub 2015 Apr 14. Review.

PMID:
25881871
23.

Synthesis and properties of 2'-deoxy-2',4'-difluoroarabinose-modified nucleic acids.

Martínez-Montero S, Deleavey GF, Dierker-Viik A, Lindovska P, Ilina T, Portella G, Orozco M, Parniak MA, González C, Damha MJ.

J Org Chem. 2015 Mar 20;80(6):3083-91. doi: 10.1021/jo502948t. Epub 2015 Mar 5.

24.

Structure and dynamics of oligonucleotides in the gas phase.

Arcella A, Dreyer J, Ippoliti E, Ivani I, Portella G, Gabelica V, Carloni P, Orozco M.

Angew Chem Int Ed Engl. 2015 Jan 7;54(2):467-71. doi: 10.1002/anie.201406910. Epub 2014 Nov 21.

PMID:
25417598
25.

High levels of GPR30 protein in human testicular carcinoma in situ and seminomas correlate with low levels of estrogen receptor-beta and indicate a switch in estrogen responsiveness.

Boscia F, Passaro C, Gigantino V, Perdonà S, Franco R, Portella G, Chieffi S, Chieffi P.

J Cell Physiol. 2015 Jun;230(6):1290-7. doi: 10.1002/jcp.24864.

PMID:
25413376
26.

JC virus antibody index in natalizumab-treated patients: correlations with John Cunningham virus DNA and C-reactive protein level.

Lanzillo R, Liuzzi R, Vallefuoco L, Moccia M, Amato L, Vacca G, Vacchiano V, Portella G, Brescia Morra V.

Ther Clin Risk Manag. 2014 Oct 9;10:807-14. doi: 10.2147/TCRM.S63295. eCollection 2014.

27.

PARP inhibitor olaparib increases the oncolytic activity of dl922-947 in in vitro and in vivo model of anaplastic thyroid carcinoma.

Passaro C, Volpe M, Botta G, Scamardella E, Perruolo G, Gillespie D, Libertini S, Portella G.

Mol Oncol. 2015 Jan;9(1):78-92. doi: 10.1016/j.molonc.2014.07.022. Epub 2014 Aug 2.

28.

Prevalence of herpes simplex virus 1 and 2 antibodies in patients with autism spectrum disorders.

Gentile I, Zappulo E, Bonavolta R, Maresca R, Riccio MP, Buonomo AR, Portella G, Vallefuoco L, Settimi A, Pascotto A, Borgia G, Bravaccio C.

In Vivo. 2014 Jul-Aug;28(4):667-71.

PMID:
24982239
29.

Exposure to Varicella Zoster Virus is higher in children with autism spectrum disorder than in healthy controls. Results from a case-control study.

Gentile I, Zappulo E, Bonavolta R, Maresca R, Riccio MP, Buonomo AR, Portella G, Settimi A, Pascotto A, Borgia G, Bravaccio C.

In Vivo. 2014 Jul-Aug;28(4):627-31.

PMID:
24982233
30.

Prevalence and titre of antibodies to cytomegalovirus and epstein-barr virus in patients with autism spectrum disorder.

Gentile I, Zappulo E, Bonavolta R, Maresca R, Messana T, Buonomo AR, Portella G, Sorrentino R, Settimi A, Pascotto A, Borgia G, Bravaccio C.

In Vivo. 2014 Jul-Aug;28(4):621-6.

PMID:
24982232
31.

Structure and properties of DNA in apolar solvents.

Arcella A, Portella G, Collepardo-Guevara R, Chakraborty D, Wales DJ, Orozco M.

J Phys Chem B. 2014 Jul 24;118(29):8540-8. doi: 10.1021/jp503816r. Epub 2014 Jul 14.

32.

Evaluation of the siemens HIV antigen-antibody immunoassay.

Vallefuoco L, Aden Abdi F, Sorrentino R, Spalletti-Cernia D, Mazzarella C, Barbato S, Perna E, Buffolano W, Di Nicuolo G, Portella G.

Intervirology. 2014;57(2):106-11. doi: 10.1159/000358879. Epub 2014 Feb 19.

33.

Aorta-to-right ventricular outflow tract fistula with coronary cusp prolapse.

Tiwari KK, Salvati AC, di Summa M, Barbieri A, Portella G, Strada G.

Asian Cardiovasc Thorac Ann. 2013 Apr;21(2):193-5. doi: 10.1177/0218492312449011.

PMID:
24532619
34.

MD and NMR analyses of choline and TMA binding to duplex DNA: on the origins of aberrant sequence-dependent stability by alkyl cations in aqueous and water-free solvents.

Portella G, Germann MW, Hud NV, Orozco M.

J Am Chem Soc. 2014 Feb 26;136(8):3075-86. doi: 10.1021/ja410698u. Epub 2014 Feb 14.

PMID:
24490755
35.

Specific loop modifications of the thrombin-binding aptamer trigger the formation of parallel structures.

Aviñó A, Portella G, Ferreira R, Gargallo R, Mazzini S, Gabelica V, Orozco M, Eritja R.

FEBS J. 2014 Feb;281(4):1085-99. doi: 10.1111/febs.12670. Epub 2014 Jan 2.

36.

Prevalence of HHV-6 and HHV-8 antibodies in patients with autism spectrum disorders.

Gentile I, Zappulo E, Coppola N, Bonavolta R, Portella G, Cernia DS, Riccio MP, Settimi A, Pascotto A, Borgia G, Bravaccio C.

In Vivo. 2013 Nov-Dec;27(6):843-9.

PMID:
24292591
37.

Understanding the connection between epigenetic DNA methylation and nucleosome positioning from computer simulations.

Portella G, Battistini F, Orozco M.

PLoS Comput Biol. 2013;9(11):e1003354. doi: 10.1371/journal.pcbi.1003354. Epub 2013 Nov 21.

38.

Backbone FC-H···O hydrogen bonds in 2'F-substituted nucleic acids.

Martin-Pintado N, Deleavey GF, Portella G, Campos-Olivas R, Orozco M, Damha MJ, González C.

Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12065-8. doi: 10.1002/anie.201305710. Epub 2013 Sep 23. No abstract available.

PMID:
24115468
39.

In vivo antiviral activity of telbivudine against HIV-1: a case report.

Gentile I, Bonadies G, Carleo MA, Buonomo AR, Borrelli F, Portella G, Borgia G.

Infez Med. 2013 Sep;21(3):216-9.

40.

Clinico-pathological significance of hepatitis C virus core antigen levels in chronic infection.

Durante-Mangoni E, Vallefuoco L, Sorrentino R, Iossa D, Perna E, Molaro R, Braschi U, Zampino R, Sodano G, Adinolfi LE, Utili R, Portella G.

J Med Virol. 2013 Nov;85(11):1913-8. doi: 10.1002/jmv.23672. Epub 2013 Jul 29.

PMID:
23897630
41.

Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells.

Passaro C, Abagnale A, Libertini S, Volpe M, Botta G, Cella L, Pacelli R, Halldèn G, Gillespie D, Portella G.

Endocr Relat Cancer. 2013 Aug 19;20(5):633-47. doi: 10.1530/ERC-13-0001. Print 2013 Oct.

PMID:
23839822
42.

Response to measles-mumps-rubella vaccine in children with autism spectrum disorders.

Gentile I, Bravaccio C, Bonavolta R, Zappulo E, Scarica S, Riccio MP, Settimi A, Portella G, Pascotto A, Borgia G.

In Vivo. 2013 May-Jun;27(3):377-82.

PMID:
23606694
43.

Dramatic effect of furanose C2' substitution on structure and stability: directing the folding of the human telomeric quadruplex with a single fluorine atom.

Martín-Pintado N, Yahyaee-Anzahaee M, Deleavey GF, Portella G, Orozco M, Damha MJ, González C.

J Am Chem Soc. 2013 Apr 10;135(14):5344-7. doi: 10.1021/ja401954t. Epub 2013 Mar 27.

PMID:
23521511
44.

Design of peptide-membrane interactions to modulate single-file water transport through modified gramicidin channels.

Portella G, Polupanow T, Zocher F, Boytsov DA, Pohl P, Diederichsen U, de Groot BL.

Biophys J. 2012 Oct 17;103(8):1698-705. doi: 10.1016/j.bpj.2012.08.059. Epub 2012 Oct 16.

45.

Oncolytic virotherapy with modified adenoviruses and novel therapeutic targets.

Halldén G, Portella G.

Expert Opin Ther Targets. 2012 Oct;16(10):945-58. doi: 10.1517/14728222.2012.712962. Epub 2012 Aug 13. Review.

PMID:
22880939
46.

Light on the structural communication in Ras GTPases.

Raimondi F, Felline A, Portella G, Orozco M, Fanelli F.

J Biomol Struct Dyn. 2013;31(2):142-57. doi: 10.1080/07391102.2012.698379. Epub 2012 Aug 1.

PMID:
22849539
47.

The cobas p 630 instrument: a dedicated pre-analytic solution to optimize COBAS® AmpliPrep/COBAS® TaqMan® system workflow and turn-around-time.

Vallefuoco L, Sorrentino R, Spalletti Cernia D, Colucci G, Portella G.

J Virol Methods. 2012 Dec;186(1-2):86-8. doi: 10.1016/j.jviromet.2012.07.020. Epub 2012 Jul 22.

PMID:
22827959
48.

Inhibition of autophagy enhances the effects of E1A-defective oncolytic adenovirus dl922-947 against glioma cells in vitro and in vivo.

Botta G, Passaro C, Libertini S, Abagnale A, Barbato S, Maione AS, Hallden G, Beguinot F, Formisano P, Portella G.

Hum Gene Ther. 2012 Jun;23(6):623-34. doi: 10.1089/hum.2011.120. Epub 2012 Jun 5.

PMID:
22475378
49.

Structure of triplex DNA in the gas phase.

Arcella A, Portella G, Ruiz ML, Eritja R, Vilaseca M, Gabelica V, Orozco M.

J Am Chem Soc. 2012 Apr 18;134(15):6596-606. doi: 10.1021/ja209786t. Epub 2012 Apr 6.

PMID:
22420643
50.

Nucleotide binding switches the information flow in ras GTPases.

Raimondi F, Portella G, Orozco M, Fanelli F.

PLoS Comput Biol. 2011 Mar;7(3):e1001098. doi: 10.1371/journal.pcbi.1001098. Epub 2011 Mar 3.

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