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Items: 7


Multisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegans.

Portegijs V, Fielmich LE, Galli M, Schmidt R, Muñoz J, van Mourik T, Akhmanova A, Heck AJ, Boxem M, van den Heuvel S.

PLoS Genet. 2016 Oct 6;12(10):e1006291. doi: 10.1371/journal.pgen.1006291. eCollection 2016 Oct.


Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis.

van Schendel R, Roerink SF, Portegijs V, van den Heuvel S, Tijsterman M.

Nat Commun. 2015 Jun 16;6:7394. doi: 10.1038/ncomms8394.


CRISPR/Cas9-targeted mutagenesis in Caenorhabditis elegans.

Waaijers S, Portegijs V, Kerver J, Lemmens BB, Tijsterman M, van den Heuvel S, Boxem M.

Genetics. 2013 Nov;195(3):1187-91. doi: 10.1534/genetics.113.156299. Epub 2013 Aug 26.


F-actin asymmetry and the endoplasmic reticulum-associated TCC-1 protein contribute to stereotypic spindle movements in the Caenorhabditis elegans embryo.

Berends CW, Muñoz J, Portegijs V, Schmidt R, Grigoriev I, Boxem M, Akhmanova A, Heck AJ, van den Heuvel S.

Mol Biol Cell. 2013 Jul;24(14):2201-15. doi: 10.1091/mbc.E13-02-0076. Epub 2013 May 22.


Caenorhabditis elegans cyclin D/CDK4 and cyclin E/CDK2 induce distinct cell cycle re-entry programs in differentiated muscle cells.

Korzelius J, The I, Ruijtenberg S, Prinsen MB, Portegijs V, Middelkoop TC, Groot Koerkamp MJ, Holstege FC, Boxem M, van den Heuvel S.

PLoS Genet. 2011 Nov;7(11):e1002362. doi: 10.1371/journal.pgen.1002362. Epub 2011 Nov 10.


aPKC phosphorylates NuMA-related LIN-5 to position the mitotic spindle during asymmetric division.

Galli M, Muñoz J, Portegijs V, Boxem M, Grill SW, Heck AJ, van den Heuvel S.

Nat Cell Biol. 2011 Aug 21;13(9):1132-8. doi: 10.1038/ncb2315.


C. elegans MCM-4 is a general DNA replication and checkpoint component with an epidermis-specific requirement for growth and viability.

Korzelius J, The I, Ruijtenberg S, Portegijs V, Xu H, Horvitz HR, van den Heuvel S.

Dev Biol. 2011 Feb 15;350(2):358-69. doi: 10.1016/j.ydbio.2010.12.009. Epub 2010 Dec 10.

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