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Items: 8


Tityus serrulatus Scorpion Venom: In Vitro Tests and Their Correlation with In Vivo Lethal Dose Assay.

Cajado-Carvalho D, Galvão J, Kuniyoshi AK, Carneiro PDS, Paes Leme AF, Pauletti BA, Marengo EB, Portaro FV.

Toxins (Basel). 2017 Nov 23;9(12). pii: E380. doi: 10.3390/toxins9120380.


Impaired expression of CXCL5 and matrix metalloproteinases in the lungs of mice with high susceptibility to Streptococcus pneumoniae infection.

Mancuso RI, Miyaji EN, Silva CCF, Portaro FV, Soares-Schanoski A, Ribeiro OG, Oliveira MLS.

Immun Inflamm Dis. 2018 Mar;6(1):128-142. doi: 10.1002/iid3.205. Epub 2017 Nov 9.


In vitro cleavage of bioactive peptides by peptidases from Bothrops jararaca venom and its neutralization by bothropic antivenom produced by Butantan Institute: Major contribution of serine peptidases.

Kuniyoshi AK, Kodama RT, Moraes LHF, Duzzi B, Iwai LK, Lima IF, Cajado-Carvalho D, Portaro FV.

Toxicon. 2017 Oct;137:114-119. doi: 10.1016/j.toxicon.2017.07.020. Epub 2017 Jul 28.


Peptides derived from plasma proteins released by bothropasin, a metalloprotease present in the Bothrops jararaca venom.

Silva CCF, Menezes MC, Palomino M, Oliveira AK, Iwai LK, Faria M, Portaro FV.

Toxicon. 2017 Oct;137:65-72. doi: 10.1016/j.toxicon.2017.07.009. Epub 2017 Jul 8.


Insights into the Hypertensive Effects of Tityus serrulatus Scorpion Venom: Purification of an Angiotensin-Converting Enzyme-Like Peptidase.

Cajado-Carvalho D, Kuniyoshi AK, Duzzi B, Iwai LK, Oliveira ÚC, Junqueira de Azevedo IL, Kodama RT, Portaro FV.

Toxins (Basel). 2016 Nov 24;8(12). pii: E348.


[des-Arg(1)]-Proctolin: A novel NEP-like enzyme inhibitor identified in Tityus serrulatus venom.

Duzzi B, Cajado-Carvalho D, Kuniyoshi AK, Kodama RT, Gozzo FC, Fioramonte M, Tambourgi DV, Portaro FV, Rioli V.

Peptides. 2016 Jun;80:18-24. doi: 10.1016/j.peptides.2015.05.013. Epub 2015 Jun 6.


New proline-rich oligopeptides from the venom of African adders: Insights into the hypotensive effect of the venoms.

Kodama RT, Cajado-Carvalho D, Kuniyoshi AK, Kitano ES, Tashima AK, Barna BF, Takakura AC, Serrano SM, Dias-Da-Silva W, Tambourgi DV, Portaro FV.

Biochim Biophys Acta. 2015 Jun;1850(6):1180-7. doi: 10.1016/j.bbagen.2015.02.005. Epub 2015 Feb 14.


Neuropeptide Y family-degrading metallopeptidases in the Tityus serrulatus venom partially blocked by commercial antivenoms.

Cajado Carvalho D, Kuniyoshi AK, Kodama RT, Oliveira AK, Serrano SM, Tambourgi DV, Portaro FV.

Toxicol Sci. 2014 Dec;142(2):418-26. doi: 10.1093/toxsci/kfu193. Epub 2014 Sep 19.


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