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Items: 1 to 50 of 139


Functional brain activity is globally elevated by dopamine D2 receptor knockdown in the ventral tegmental area.

Martin TA, Smith HR, Luessen DJ, Chen R, Porrino LJ.

Brain Res. 2020 Jan 15;1727:146552. doi: 10.1016/j.brainres.2019.146552. Epub 2019 Nov 11.


Brain activity associated with social exclusion overlaps with drug-related frontal-striatal circuitry in cocaine users: A pilot study.

Hanlon CA, Shannon EE, Porrino LJ.

Neurobiol Stress. 2018 Oct 30;10:100137. doi: 10.1016/j.ynstr.2018.10.005. eCollection 2019 Feb.


Regional elevations in microglial activation and cerebral glucose utilization in frontal white matter tracts of rhesus monkeys following prolonged cocaine self-administration.

Smith HR, Beveridge TJR, Nader SH, Nader MA, Porrino LJ.

Brain Struct Funct. 2019 May;224(4):1417-1428. doi: 10.1007/s00429-019-01846-4. Epub 2019 Feb 12.


Neurophysiological capacity in a working memory task differentiates dependent from nondependent heavy drinkers and controls.

Wesley MJ, Lile JA, Fillmore MT, Porrino LJ.

Drug Alcohol Depend. 2017 Jun 1;175:24-35. doi: 10.1016/j.drugalcdep.2017.01.029. Epub 2017 Mar 21.


Social Status in Monkeys: Effects of Social Confrontation on Brain Function and Cocaine Self-Administration.

Gould RW, Czoty PW, Porrino LJ, Nader MA.

Neuropsychopharmacology. 2017 Apr;42(5):1093-1102. doi: 10.1038/npp.2016.285. Epub 2016 Dec 27.


Moderate-Heavy Alcohol Consumption Lifestyle in Older Adults Is Associated with Altered Central Executive Network Community Structure during Cognitive Task.

Mayhugh RE, Moussa MN, Simpson SL, Lyday RG, Burdette JH, Porrino LJ, Laurienti PJ.

PLoS One. 2016 Aug 5;11(8):e0160214. doi: 10.1371/journal.pone.0160214. eCollection 2016.


Neural Correlates of Exposure to Cocaine Cues in Rhesus Monkeys: Modulation by the Dopamine Transporter.

Porrino LJ, Miller MD, Smith HR, Nader SH, Nader MA.

Biol Psychiatry. 2016 Nov 1;80(9):702-710. doi: 10.1016/j.biopsych.2016.02.015. Epub 2016 Feb 23.


Abnormal medial prefrontal cortex activity in heavy cannabis users during conscious emotional evaluation.

Wesley MJ, Lile JA, Hanlon CA, Porrino LJ.

Psychopharmacology (Berl). 2016 Mar;233(6):1035-44. doi: 10.1007/s00213-015-4180-y. Epub 2015 Dec 22.


Effects of abstinence from chronic cocaine self-administration on nonhuman primate dorsal and ventral noradrenergic bundle terminal field structures.

Smith HR, Beveridge TJ, Nader MA, Porrino LJ.

Brain Struct Funct. 2016 Jun;221(5):2703-15. doi: 10.1007/s00429-015-1066-z. Epub 2015 May 27.


Functional consequences of cocaine expectation: findings in a non-human primate model of cocaine self-administration.

Porrino LJ, Beveridge TJ, Smith HR, Nader MA.

Addict Biol. 2016 May;21(3):519-29. doi: 10.1111/adb.12231. Epub 2015 Feb 15.


Long-term moderate alcohol consumption does not exacerbate age-related cognitive decline in healthy, community-dwelling older adults.

Moussa MN, Simpson SL, Mayhugh RE, Grata ME, Burdette JH, Porrino LJ, Laurienti PJ.

Front Aging Neurosci. 2015 Jan 5;6:341. doi: 10.3389/fnagi.2014.00341. eCollection 2014.


Chronic methylphenidate treatment during early life is associated with greater ethanol intake in socially isolated rats.

Gill KE, Chappell AM, Beveridge TJ, Porrino LJ, Weiner JL.

Alcohol Clin Exp Res. 2014 Aug;38(8):2260-8. doi: 10.1111/acer.12489.


Functional consequences of cocaine re-exposure after discontinuation of cocaine availability.

Beveridge TJ, Smith HR, Nader SH, Nader MA, Porrino LJ.

Neuropharmacology. 2014 Oct;85:528-37. doi: 10.1016/j.neuropharm.2014.06.003. Epub 2014 Jun 19.


Age-related differences in advantageous decision making are associated with distinct differences in functional community structure.

Moussa MN, Wesley MJ, Porrino LJ, Hayasaka S, Bechara A, Burdette JH, Laurienti PJ.

Brain Connect. 2014 Apr;4(3):193-202. doi: 10.1089/brain.2013.0184. Epub 2014 Apr 4.


Regionally-specific alterations in myelin proteins in nonhuman primate white matter following prolonged cocaine self-administration.

Smith HR, Beveridge TJ, Nader MA, Porrino LJ.

Drug Alcohol Depend. 2014 Apr 1;137:143-7. doi: 10.1016/j.drugalcdep.2014.01.015. Epub 2014 Jan 30.


Withdrawal from extended-access cocaine self-administration results in dysregulated functional activity and altered locomotor activity in rats.

Calipari ES, Beveridge TJ, Jones SR, Porrino LJ.

Eur J Neurosci. 2013 Dec;38(12):3749-57. doi: 10.1111/ejn.12381. Epub 2013 Oct 13.


Effects of chronic methylphenidate in adolescence on later methylphenidate self-administration in rhesus monkeys.

Martelle SE, Porrino LJ, Nader MA.

Behav Pharmacol. 2013 Sep;24(5-6):478-81. doi: 10.1097/FBP.0b013e328364bfee.


The effects of rearing environment and chronic methylphenidate administration on behavior and dopamine receptors in adolescent rats.

Gill KE, Beveridge TJ, Smith HR, Porrino LJ.

Brain Res. 2013 Aug 21;1527:67-78. doi: 10.1016/j.brainres.2013.06.021. Epub 2013 Jun 24.


Recovering from cocaine: insights from clinical and preclinical investigations.

Hanlon CA, Beveridge TJ, Porrino LJ.

Neurosci Biobehav Rev. 2013 Nov;37(9 Pt A):2037-46. doi: 10.1016/j.neubiorev.2013.04.007. Epub 2013 Apr 27. Review.


Differential development of tolerance to the functional and behavioral effects of repeated baclofen treatment in rats.

Beveridge TJ, Smith HR, Porrino LJ.

Pharmacol Biochem Behav. 2013 May;106:27-32. doi: 10.1016/j.pbb.2013.03.001. Epub 2013 Mar 13.


Individual differences in decision making and reward processing predict changes in cannabis use: a prospective functional magnetic resonance imaging study.

Cousijn J, Wiers RW, Ridderinkhof KR, van den Brink W, Veltman DJ, Porrino LJ, Goudriaan AE.

Addict Biol. 2013 Nov;18(6):1013-23. doi: 10.1111/j.1369-1600.2012.00498.x. Epub 2012 Sep 21.


Acute cocaine induced deficits in cognitive performance in rhesus macaque monkeys treated with baclofen.

Porrino LJ, Hampson RE, Opris I, Deadwyler SA.

Psychopharmacology (Berl). 2013 Jan;225(1):105-14. doi: 10.1007/s00213-012-2798-6. Epub 2012 Jul 27.


Chronic treatment with extended release methylphenidate does not alter dopamine systems or increase vulnerability for cocaine self-administration: a study in nonhuman primates.

Gill KE, Pierre PJ, Daunais J, Bennett AJ, Martelle S, Gage HD, Swanson JM, Nader MA, Porrino LJ.

Neuropsychopharmacology. 2012 Nov;37(12):2555-65. doi: 10.1038/npp.2012.117. Epub 2012 Jul 18.


Neuroanatomy of dopamine: reward and addiction.

Taber KH, Black DN, Porrino LJ, Hurley RA.

J Neuropsychiatry Clin Neurosci. 2012 Winter;24(1):1-4. doi: 10.1176/appi.neuropsych.24.1.1. Review. No abstract available.


Nonhuman primate models of addiction and PET imaging: dopamine system dysregulation.

Gould RW, Porrino LJ, Nader MA.

Curr Top Behav Neurosci. 2012;11:25-44. doi: 10.1007/7854_2011_168.


Elevated gray and white matter densities in cocaine abstainers compared to current users.

Hanlon CA, Dufault DL, Wesley MJ, Porrino LJ.

Psychopharmacology (Berl). 2011 Dec;218(4):681-92. doi: 10.1007/s00213-011-2360-y. Epub 2011 Jun 22.


Group II metabotropic glutamate receptors in the striatum of non-human primates: dysregulation following chronic cocaine self-administration.

Beveridge TJ, Smith HR, Nader MA, Porrino LJ.

Neurosci Lett. 2011 May 27;496(1):15-9. doi: 10.1016/j.neulet.2011.03.077. Epub 2011 Mar 31.


The association between frontal-striatal connectivity and sensorimotor control in cocaine users.

Hanlon CA, Wesley MJ, Stapleton JR, Laurienti PJ, Porrino LJ.

Drug Alcohol Depend. 2011 Jun 1;115(3):240-3. doi: 10.1016/j.drugalcdep.2010.11.008. Epub 2010 Dec 28.


Poor decision-making by chronic marijuana users is associated with decreased functional responsiveness to negative consequences.

Wesley MJ, Hanlon CA, Porrino LJ.

Psychiatry Res. 2011 Jan 30;191(1):51-9. doi: 10.1016/j.pscychresns.2010.10.002. Epub 2010 Dec 9.


Effects of cocaine rewards on neural representations of cognitive demand in nonhuman primates.

Hampson RE, Porrino LJ, Opris I, Stanford T, Deadwyler SA.

Psychopharmacology (Berl). 2011 Jan;213(1):105-18. doi: 10.1007/s00213-010-2017-2. Epub 2010 Sep 24.


Local cerebral glucose utilization in rats exposed to an enriched environment: a comparison to impoverishment.

Läck AK, Gill KE, Porrino LJ.

Pharmacol Biochem Behav. 2010 Oct;96(4):521-5. doi: 10.1016/j.pbb.2010.07.015. Epub 2010 Jul 27.


Loss of laterality in chronic cocaine users: an fMRI investigation of sensorimotor control.

Hanlon CA, Wesley MJ, Roth AJ, Miller MD, Porrino LJ.

Psychiatry Res. 2010 Jan 30;181(1):15-23. doi: 10.1016/j.pscychresns.2009.07.009.


Loss of functional specificity in the dorsal striatum of chronic cocaine users.

Hanlon CA, Wesley MJ, Porrino LJ.

Drug Alcohol Depend. 2009 Jun 1;102(1-3):88-94. doi: 10.1016/j.drugalcdep.2009.01.005. Epub 2009 Mar 4.


Mechanisms underlying cognitive enhancement and reversal of cognitive deficits in nonhuman primates by the ampakine CX717.

Hampson RE, España RA, Rogers GA, Porrino LJ, Deadwyler SA.

Psychopharmacology (Berl). 2009 Jan;202(1-3):355-69. doi: 10.1007/s00213-008-1360-z. Epub 2008 Nov 5.


Abstinence from chronic cocaine self-administration alters striatal dopamine systems in rhesus monkeys.

Beveridge TJ, Smith HR, Nader MA, Porrino LJ.

Neuropsychopharmacology. 2009 Apr;34(5):1162-71. doi: 10.1038/npp.2008.135. Epub 2008 Sep 3.


Review. Parallel studies of cocaine-related neural and cognitive impairment in humans and monkeys.

Beveridge TJ, Gill KE, Hanlon CA, Porrino LJ.

Philos Trans R Soc Lond B Biol Sci. 2008 Oct 12;363(1507):3257-66. doi: 10.1098/rstb.2008.0102. Review.


The comparative distributions of the monoamine transporters in the rodent, monkey, and human amygdala.

Smith HR, Porrino LJ.

Brain Struct Funct. 2008 Sep;213(1-2):73-91. doi: 10.1007/s00429-008-0176-2. Epub 2008 Feb 19. Review.


The effects of cocaine: a shifting target over the course of addiction.

Porrino LJ, Smith HR, Nader MA, Beveridge TJ.

Prog Neuropsychopharmacol Biol Psychiatry. 2007 Nov 15;31(8):1593-600. Epub 2007 Sep 4. Review.


Chronic cocaine self-administration is associated with altered functional activity in the temporal lobes of non human primates.

Beveridge TJ, Smith HR, Daunais JB, Nader MA, Porrino LJ.

Eur J Neurosci. 2006 Jun;23(11):3109-18.


Distribution of norepinephrine transporters in the non-human primate brain.

Smith HR, Beveridge TJ, Porrino LJ.

Neuroscience. 2006;138(2):703-14. Epub 2006 Jan 20.


Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates.

Porrino LJ, Daunais JB, Rogers GA, Hampson RE, Deadwyler SA.

PLoS Biol. 2005 Sep;3(9):e299. Epub 2005 Aug 23.


Effects of chronic cocaine self-administration on norepinephrine transporters in the nonhuman primate brain.

Beveridge TJ, Smith HR, Nader MA, Porrino LJ.

Psychopharmacology (Berl). 2005 Aug;180(4):781-8. Epub 2005 Sep 14.


Time-dependent changes in receptor/G-protein coupling in rat brain following chronic monoamine transporter blockade.

O'Connor KA, Porrino LJ, Davies HM, Childers SR.

J Pharmacol Exp Ther. 2005 May;313(2):510-7. Epub 2005 Jan 11.


Cortical 3 alpha-hydroxy-5 alpha-pregnan-20-one levels after acute administration of Delta 9-tetrahydrocannabinol, cocaine and morphine.

Grobin AC, VanDoren MJ, Porrino LJ, Morrow AL.

Psychopharmacology (Berl). 2005 May;179(3):544-50. Epub 2004 Dec 24.


Functional effects of cocaine self-administration in primate brain regions regulating cardiovascular function.

Beveridge TJ, Smith HR, Nader MA, Porrino LJ.

Neurosci Lett. 2004 Nov 11;370(2-3):201-5.


Cannabinoid physiology and pharmacology: 30 years of progress.

Howlett AC, Breivogel CS, Childers SR, Deadwyler SA, Hampson RE, Porrino LJ.

Neuropharmacology. 2004;47 Suppl 1:345-58. Review.


Long-term heavy marijuana users make costly decisions on a gambling task.

Whitlow CT, Liguori A, Livengood LB, Hart SL, Mussat-Whitlow BJ, Lamborn CM, Laurienti PJ, Porrino LJ.

Drug Alcohol Depend. 2004 Oct 5;76(1):107-11.


Cocaine self-administration produces a progressive involvement of limbic, association, and sensorimotor striatal domains.

Porrino LJ, Lyons D, Smith HR, Daunais JB, Nader MA.

J Neurosci. 2004 Apr 7;24(14):3554-62.


The expanding effects of cocaine: studies in a nonhuman primate model of cocaine self-administration.

Porrino LJ, Daunais JB, Smith HR, Nader MA.

Neurosci Biobehav Rev. 2004 Jan;27(8):813-20. Review.


Patterns of functional activity associated with cocaine self-administration in the rat change over time.

Macey DJ, Rice WN, Freedland CS, Whitlow CT, Porrino LJ.

Psychopharmacology (Berl). 2004 Apr;172(4):384-92. Epub 2003 Dec 11.


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