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Items: 48

1.

Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway.

Mills RJ, Parker BL, Quaife-Ryan GA, Voges HK, Needham EJ, Bornot A, Ding M, Andersson H, Polla M, Elliott DA, Drowley L, Clausen M, Plowright AT, Barrett IP, Wang QD, James DE, Porrello ER, Hudson JE.

Cell Stem Cell. 2019 Jun 6;24(6):895-907.e6. doi: 10.1016/j.stem.2019.03.009. Epub 2019 Mar 28.

PMID:
30930147
2.

Differential Response to Injury in Fetal and Adolescent Sheep Hearts in the Immediate Post-myocardial Infarction Period.

Lock MC, Darby JRT, Soo JY, Brooks DA, Perumal SR, Selvanayagam JB, Seed M, Macgowan CK, Porrello ER, Tellam RL, Morrison JL.

Front Physiol. 2019 Mar 5;10:208. doi: 10.3389/fphys.2019.00208. eCollection 2019.

3.

Upsizing Neonatal Heart Regeneration.

Mahmoud AI, Porrello ER.

Circulation. 2018 Dec 11;138(24):2817-2819. doi: 10.1161/CIRCULATIONAHA.118.037333. No abstract available.

PMID:
30565992
4.

Development of a human skeletal micro muscle platform with pacing capabilities.

Mills RJ, Parker BL, Monnot P, Needham EJ, Vivien CJ, Ferguson C, Parton RG, James DE, Porrello ER, Hudson JE.

Biomaterials. 2019 Apr;198:217-227. doi: 10.1016/j.biomaterials.2018.11.030. Epub 2018 Nov 28.

PMID:
30527761
5.

A symphony of stem cells in Vienna - looking to the future.

Porrello ER, Kirkeby A.

Development. 2018 Jun 8;145(11). pii: dev163501. doi: 10.1242/dev.163501.

6.

Cardiomyocyte Functional Etiology in Heart Failure With Preserved Ejection Fraction Is Distinctive-A New Preclinical Model.

Curl CL, Danes VR, Bell JR, Raaijmakers AJA, Ip WTK, Chandramouli C, Harding TW, Porrello ER, Erickson JR, Charchar FJ, Kompa AR, Edgley AJ, Crossman DJ, Soeller C, Mellor KM, Kalman JM, Harrap SB, Delbridge LMD.

J Am Heart Assoc. 2018 Jun 1;7(11). pii: e007451. doi: 10.1161/JAHA.117.007451.

7.

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network.

Anderson DJ, Kaplan DI, Bell KM, Koutsis K, Haynes JM, Mills RJ, Phelan DG, Qian EL, Leitoguinho AR, Arasaratnam D, Labonne T, Ng ES, Davis RP, Casini S, Passier R, Hudson JE, Porrello ER, Costa MW, Rafii A, Curl CL, Delbridge LM, Harvey RP, Oshlack A, Cheung MM, Mummery CL, Petrou S, Elefanty AG, Stanley EG, Elliott DA.

Nat Commun. 2018 Apr 10;9(1):1373. doi: 10.1038/s41467-018-03714-x.

8.

TrawlerWeb: an online de novo motif discovery tool for next-generation sequencing datasets.

Dang LT, Tondl M, Chiu MHH, Revote J, Paten B, Tano V, Tokolyi A, Besse F, Quaife-Ryan G, Cumming H, Drvodelic MJ, Eichenlaub MP, Hallab JC, Stolper JS, Rossello FJ, Bogoyevitch MA, Jans DA, Nim HT, Porrello ER, Hudson JE, Ramialison M.

BMC Genomics. 2018 Apr 5;19(1):238. doi: 10.1186/s12864-018-4630-0.

9.

FunSel: Mesenchymal Stromal Cells Stay for the Party.

Hudson JE, Porrello ER.

Circulation. 2017 Oct 17;136(16):1525-1527. doi: 10.1161/CIRCULATIONAHA.117.030795. No abstract available.

PMID:
29038207
10.

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest.

Mills RJ, Titmarsh DM, Koenig X, Parker BL, Ryall JG, Quaife-Ryan GA, Voges HK, Hodson MP, Ferguson C, Drowley L, Plowright AT, Needham EJ, Wang QD, Gregorevic P, Xin M, Thomas WG, Parton RG, Nielsen LK, Launikonis BS, James DE, Elliott DA, Porrello ER, Hudson JE.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8372-E8381. doi: 10.1073/pnas.1707316114. Epub 2017 Sep 15.

11.

Cryoinjury Model for Tissue Injury and Repair in Bioengineered Human Striated Muscle.

Mills RJ, Voges HK, Porrello ER, Hudson JE.

Methods Mol Biol. 2017;1668:209-224. doi: 10.1007/978-1-4939-7283-8_15.

PMID:
28842912
12.

Multicellular Transcriptional Analysis of Mammalian Heart Regeneration.

Quaife-Ryan GA, Sim CB, Ziemann M, Kaspi A, Rafehi H, Ramialison M, El-Osta A, Hudson JE, Porrello ER.

Circulation. 2017 Sep 19;136(12):1123-1139. doi: 10.1161/CIRCULATIONAHA.117.028252. Epub 2017 Jul 21.

13.

Cavin-1 deficiency modifies myocardial and coronary function, stretch responses and ischaemic tolerance: roles of NOS over-activity.

Kaakinen M, Reichelt ME, Ma Z, Ferguson C, Martel N, Porrello ER, Hudson JE, Thomas WG, Parton RG, Headrick JP.

Basic Res Cardiol. 2017 May;112(3):24. doi: 10.1007/s00395-017-0613-6. Epub 2017 Mar 25.

PMID:
28343262
14.

Periostin paves the way for neonatal heart regeneration.

Hudson JE, Porrello ER.

Cardiovasc Res. 2017 May 1;113(6):556-558. doi: 10.1093/cvr/cvx039. No abstract available.

PMID:
28339887
15.

Development of a human cardiac organoid injury model reveals innate regenerative potential.

Voges HK, Mills RJ, Elliott DA, Parton RG, Porrello ER, Hudson JE.

Development. 2017 Mar 15;144(6):1118-1127. doi: 10.1242/dev.143966. Epub 2017 Feb 7.

16.

Evolution, comparative biology and ontogeny of vertebrate heart regeneration.

Vivien CJ, Hudson JE, Porrello ER.

NPJ Regen Med. 2016 Jul 28;1:16012. doi: 10.1038/npjregenmed.2016.12. eCollection 2016. Review.

17.

Induction of Human iPSC-Derived Cardiomyocyte Proliferation Revealed by Combinatorial Screening in High Density Microbioreactor Arrays.

Titmarsh DM, Glass NR, Mills RJ, Hidalgo A, Wolvetang EJ, Porrello ER, Hudson JE, Cooper-White JJ.

Sci Rep. 2016 Apr 21;6:24637. doi: 10.1038/srep24637.

18.

Resetting the epigenome for heart regeneration.

Quaife-Ryan GA, Sim CB, Porrello ER, Hudson JE.

Semin Cell Dev Biol. 2016 Oct;58:2-13. doi: 10.1016/j.semcdb.2015.12.021. Epub 2016 Jan 7. Review.

PMID:
26773213
19.

Regulation of microRNA during cardiomyocyte maturation in sheep.

Morrison JL, Zhang S, Tellam RL, Brooks DA, McMillen IC, Porrello ER, Botting KJ.

BMC Genomics. 2015 Jul 22;16:541. doi: 10.1186/s12864-015-1693-z.

20.

Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation.

Foster SR, Porrello ER, Stefani M, Smith NJ, Molenaar P, dos Remedios CG, Thomas WG, Ramialison M.

Naunyn Schmiedebergs Arch Pharmacol. 2015 Oct;388(10):1009-27. doi: 10.1007/s00210-015-1118-1. Epub 2015 May 20.

PMID:
25986534
21.

Dynamic changes in the cardiac methylome during postnatal development.

Sim CB, Ziemann M, Kaspi A, Harikrishnan KN, Ooi J, Khurana I, Chang L, Hudson JE, El-Osta A, Porrello ER.

FASEB J. 2015 Apr;29(4):1329-43. doi: 10.1096/fj.14-264093. Epub 2014 Dec 9.

PMID:
25491312
22.

Therapeutic silencing of miR-652 restores heart function and attenuates adverse remodeling in a setting of established pathological hypertrophy.

Bernardo BC, Nguyen SS, Winbanks CE, Gao XM, Boey EJ, Tham YK, Kiriazis H, Ooi JY, Porrello ER, Igoor S, Thomas CJ, Gregorevic P, Lin RC, Du XJ, McMullen JR.

FASEB J. 2014 Dec;28(12):5097-110. doi: 10.1096/fj.14-253856. Epub 2014 Aug 21.

PMID:
25145628
23.

A neonatal blueprint for cardiac regeneration.

Porrello ER, Olson EN.

Stem Cell Res. 2014 Nov;13(3 Pt B):556-70. doi: 10.1016/j.scr.2014.06.003. Epub 2014 Jul 9. Review.

24.

Concise review: new frontiers in microRNA-based tissue regeneration.

Frith JE, Porrello ER, Cooper-White JJ.

Stem Cells Transl Med. 2014 Aug;3(8):969-76. doi: 10.5966/sctm.2014-0032. Epub 2014 May 29. Review.

25.

Macrophages are required for neonatal heart regeneration.

Aurora AB, Porrello ER, Tan W, Mahmoud AI, Hill JA, Bassel-Duby R, Sadek HA, Olson EN.

J Clin Invest. 2014 Mar;124(3):1382-92. doi: 10.1172/JCI72181. Epub 2014 Feb 24.

26.

Surgical models for cardiac regeneration in neonatal mice.

Mahmoud AI, Porrello ER, Kimura W, Olson EN, Sadek HA.

Nat Protoc. 2014 Feb;9(2):305-11. doi: 10.1038/nprot.2014.021. Epub 2014 Jan 16.

27.

Hippo pathway effector Yap promotes cardiac regeneration.

Xin M, Kim Y, Sutherland LB, Murakami M, Qi X, McAnally J, Porrello ER, Mahmoud AI, Tan W, Shelton JM, Richardson JA, Sadek HA, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13839-44. doi: 10.1073/pnas.1313192110. Epub 2013 Aug 5.

28.

The non-coding road towards cardiac regeneration.

Hudson JE, Porrello ER.

J Cardiovasc Transl Res. 2013 Dec;6(6):909-23. Review.

PMID:
23797382
29.

Expression, regulation and putative nutrient-sensing function of taste GPCRs in the heart.

Foster SR, Porrello ER, Purdue B, Chan HW, Voigt A, Frenzel S, Hannan RD, Moritz KM, Simmons DG, Molenaar P, Roura E, Boehm U, Meyerhof W, Thomas WG.

PLoS One. 2013 May 15;8(5):e64579. doi: 10.1371/journal.pone.0064579. Print 2013.

30.

microRNAs in cardiac development and regeneration.

Porrello ER.

Clin Sci (Lond). 2013 Aug;125(4):151-66. doi: 10.1042/CS20130011. Review.

PMID:
23634935
31.

Meis1 regulates postnatal cardiomyocyte cell cycle arrest.

Mahmoud AI, Kocabas F, Muralidhar SA, Kimura W, Koura AS, Thet S, Porrello ER, Sadek HA.

Nature. 2013 May 9;497(7448):249-253. doi: 10.1038/nature12054. Epub 2013 Apr 17.

32.

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family.

Porrello ER, Mahmoud AI, Simpson E, Johnson BA, Grinsfelder D, Canseco D, Mammen PP, Rothermel BA, Olson EN, Sadek HA.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):187-92. doi: 10.1073/pnas.1208863110. Epub 2012 Dec 17.

33.

Turning back the cardiac regenerative clock: lessons from the neonate.

Mahmoud AI, Porrello ER.

Trends Cardiovasc Med. 2012 Jul;22(5):128-33. doi: 10.1016/j.tcm.2012.07.008. Epub 2012 Aug 14. Review.

PMID:
22902092
34.

The hypoxic epicardial and subepicardial microenvironment.

Kocabas F, Mahmoud AI, Sosic D, Porrello ER, Chen R, Garcia JA, DeBerardinis RJ, Sadek HA.

J Cardiovasc Transl Res. 2012 Oct;5(5):654-65. Epub 2012 May 8. Erratum in: J Cardiovasc Transl Res. 2012 Oct;5(5):666.

PMID:
22566269
35.

Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures.

O'Callaghan EL, Bassi JK, Porrello ER, Delbridge LM, Thomas WG, Allen AM.

J Neurochem. 2011 Oct;119(1):18-26. doi: 10.1111/j.1471-4159.2011.07406.x. Epub 2011 Aug 22.

36.

MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes.

Porrello ER, Johnson BA, Aurora AB, Simpson E, Nam YJ, Matkovich SJ, Dorn GW 2nd, van Rooij E, Olson EN.

Circ Res. 2011 Sep 2;109(6):670-9. doi: 10.1161/CIRCRESAHA.111.248880. Epub 2011 Jul 21.

37.

Heteromerization of angiotensin receptors changes trafficking and arrestin recruitment profiles.

Porrello ER, Pfleger KD, Seeber RM, Qian H, Oro C, Abogadie F, Delbridge LM, Thomas WG.

Cell Signal. 2011 Nov;23(11):1767-76. doi: 10.1016/j.cellsig.2011.06.011. Epub 2011 Jun 25.

PMID:
21740964
38.

Transient regenerative potential of the neonatal mouse heart.

Porrello ER, Mahmoud AI, Simpson E, Hill JA, Richardson JA, Olson EN, Sadek HA.

Science. 2011 Feb 25;331(6020):1078-80. doi: 10.1126/science.1200708.

39.

Building a new heart from old parts: stem cell turnover in the aging heart.

Porrello ER, Olson EN.

Circ Res. 2010 Nov 26;107(11):1292-4. doi: 10.1161/CIRCRESAHA.110.235168. No abstract available.

40.

Cardiomyocyte autophagy is regulated by angiotensin II type 1 and type 2 receptors.

Porrello ER, Delbridge LM.

Autophagy. 2009 Nov;5(8):1215-6.

PMID:
19955853
41.

Glucocorticoids suppress growth in neonatal cardiomyocytes co-expressing AT(2) and AT(1) angiotensin receptors.

Porrello ER, Meeker WF, Thomas WG, Widdop RE, Delbridge LM.

Neonatology. 2010;97(3):257-65. doi: 10.1159/000253757. Epub 2009 Oct 30.

PMID:
19887855
42.

Maternal vitamin D deficiency leads to cardiac hypertrophy in rat offspring.

Gezmish O, Tare M, Parkington HC, Morley R, Porrello ER, Bubb KJ, Black MJ.

Reprod Sci. 2010 Feb;17(2):168-76. doi: 10.1177/1933719109349536. Epub 2009 Oct 13.

PMID:
19828430
43.

Angiotensin II type 2 receptor antagonizes angiotensin II type 1 receptor-mediated cardiomyocyte autophagy.

Porrello ER, D'Amore A, Curl CL, Allen AM, Harrap SB, Thomas WG, Delbridge LM.

Hypertension. 2009 Jun;53(6):1032-40. doi: 10.1161/HYPERTENSIONAHA.108.128488. Epub 2009 May 11.

PMID:
19433781
44.

The angiotensin II type 2 (AT2) receptor: an enigmatic seven transmembrane receptor.

Porrello ER, Delbridge LM, Thomas WG.

Front Biosci (Landmark Ed). 2009 Jan 1;14:958-72. Review.

PMID:
19273111
45.

Heritable pathologic cardiac hypertrophy in adulthood is preceded by neonatal cardiac growth restriction.

Porrello ER, Bell JR, Schertzer JD, Curl CL, McMullen JR, Mellor KM, Ritchie RH, Lynch GS, Harrap SB, Thomas WG, Delbridge LM.

Am J Physiol Regul Integr Comp Physiol. 2009 Mar;296(3):R672-80. doi: 10.1152/ajpregu.90919.2008. Epub 2009 Jan 7.

46.

Early origins of cardiac hypertrophy: does cardiomyocyte attrition programme for pathological 'catch-up' growth of the heart?

Porrello ER, Widdop RE, Delbridge LM.

Clin Exp Pharmacol Physiol. 2008 Nov;35(11):1358-64. doi: 10.1111/j.1440-1681.2008.05036.x. Epub 2008 Aug 26. Review.

PMID:
18759854
47.

The intrinsic resistance of female hearts to an ischemic insult is abrogated in primary cardiac hypertrophy.

Bell JR, Porrello ER, Huggins CE, Harrap SB, Delbridge LM.

Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1514-22. doi: 10.1152/ajpheart.01283.2007. Epub 2008 Feb 1.

48.

Elevated dietary sodium intake exacerbates myocardial hypertrophy associated with cardiac-specific overproduction of angiotensin II.

Porrello ER, Huggins CE, Curl CI, Domenighetti AA, Pedrazzini T, Delbridge LM, Morgan TO.

J Renin Angiotensin Aldosterone Syst. 2004 Dec;5(4):169-75.

PMID:
15806712

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