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Items: 1 to 50 of 152

1.

The effects of maternal risk factors during pregnancy on the onset of sleep difficulties in infants at 3 months old.

Morales-Muñoz I, Saarenpää-Heikkilä O, Kylliäinen A, Pölkki P, Porkka-Heiskanen T, Paunio T, Paavonen EJ.

J Sleep Res. 2018 May 2:e12696. doi: 10.1111/jsr.12696. [Epub ahead of print]

PMID:
29722084
2.

Physiological and autonomic stress responses after prolonged sleep restriction and subsequent recovery sleep in healthy young men.

van Leeuwen WMA, Sallinen M, Virkkala J, Lindholm H, Hirvonen A, Hublin C, Porkka-Heiskanen T, Härmä M.

Sleep Biol Rhythms. 2018;16(1):45-54. doi: 10.1007/s41105-017-0122-x. Epub 2017 Sep 8.

3.

Novel concepts in sleep regulation.

Wigren HK, Porkka-Heiskanen T.

Acta Physiol (Oxf). 2018 Apr;222(4):e13017. doi: 10.1111/apha.13017. Epub 2018 Jan 19. Review.

PMID:
29253320
4.

Sleep and slow-wave activity in depressed adolescent boys: a preliminary study.

Santangeli O, Porkka-Heiskanen T, Virkkala J, Castaneda AE, Marttunen M, Paunio T, Urrila AS.

Sleep Med. 2017 Oct;38:24-30. doi: 10.1016/j.sleep.2017.06.029. Epub 2017 Jul 25.

PMID:
29031752
5.

Cholinergic basal forebrain structures are not essential for mediation of the arousing action of glutamate.

Lelkes Z, Abdurakhmanova S, Porkka-Heiskanen T.

J Sleep Res. 2018 Aug;27(4):e12605. doi: 10.1111/jsr.12605. Epub 2017 Sep 18.

PMID:
28921744
6.

Abnormalities in the Polysomnographic, Adenosine and Metabolic Response to Sleep Deprivation in an Animal Model of Hyperammonemia.

Marini S, Santangeli O, Saarelainen P, Middleton B, Chowdhury N, Skene DJ, Costa R, Porkka-Heiskanen T, Montagnese S.

Front Physiol. 2017 Aug 31;8:636. doi: 10.3389/fphys.2017.00636. eCollection 2017.

7.

Variants in calcium voltage-gated channel subunit Alpha1 C-gene (CACNA1C) are associated with sleep latency in infants.

Kantojärvi K, Liuhanen J, Saarenpää-Heikkilä O, Satomaa AL, Kylliäinen A, Pölkki P, Jaatela J, Toivola A, Milani L, Himanen SL, Porkka-Heiskanen T, Paavonen J, Paunio T.

PLoS One. 2017 Aug 9;12(8):e0180652. doi: 10.1371/journal.pone.0180652. eCollection 2017.

8.

Common Genetic Variation Near Melatonin Receptor 1A Gene Linked to Job-Related Exhaustion in Shift Workers.

Sulkava S, Ollila HM, Alasaari J, Puttonen S, Härmä M, Viitasalo K, Lahtinen A, Lindström J, Toivola A, Sulkava R, Kivimäki M, Vahtera J, Partonen T, Silander K, Porkka-Heiskanen T, Paunio T.

Sleep. 2017 Jan 1;40(1). doi: 10.1093/sleep/zsw011.

9.

Enhanced Memory Consolidation Via Automatic Sound Stimulation During Non-REM Sleep.

Leminen MM, Virkkala J, Saure E, Paajanen T, Zee PC, Santostasi G, Hublin C, Müller K, Porkka-Heiskanen T, Huotilainen M, Paunio T.

Sleep. 2017 Mar 1;40(3). doi: 10.1093/sleep/zsx003.

10.

Homeostatic response to sleep/rest deprivation by constant water flow in larval zebrafish in both dark and light conditions.

Aho V, Vainikka M, Puttonen HAJ, Ikonen HMK, Salminen T, Panula P, Porkka-Heiskanen T, Wigren HK.

J Sleep Res. 2017 Jun;26(3):394-400. doi: 10.1111/jsr.12508. Epub 2017 Mar 2.

11.

Maternal and paternal sleep during pregnancy in the Child-sleep birth cohort.

Juulia Paavonen E, Saarenpää-Heikkilä O, Pölkki P, Kylliäinen A, Porkka-Heiskanen T, Paunio T.

Sleep Med. 2017 Jan;29:47-56. doi: 10.1016/j.sleep.2016.09.011. Epub 2016 Nov 4.

PMID:
28153216
12.

Sleep and Behavior in Cross-Fostering Rats: Developmental and Sex Aspects.

Santangeli O, Lehtikuja H, Palomäki E, Wigren HK, Paunio T, Porkka-Heiskanen T.

Sleep. 2016 Dec 1;39(12):2211-2221. doi: 10.5665/sleep.6328.

13.

Altered Electroencephalographic Activity Associated with Changes in the Sleep-Wakefulness Cycle of C57BL/6J Mice in Response to a Photoperiod Shortening.

Rozov SV, Zant JC, Gurevicius K, Porkka-Heiskanen T, Panula P.

Front Behav Neurosci. 2016 Aug 31;10:168. doi: 10.3389/fnbeh.2016.00168. eCollection 2016.

14.

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses.

Aho V, Ollila HM, Kronholm E, Bondia-Pons I, Soininen P, Kangas AJ, Hilvo M, Seppälä I, Kettunen J, Oikonen M, Raitoharju E, Hyötyläinen T, Kähönen M, Viikari JS, Härmä M, Sallinen M, Olkkonen VM, Alenius H, Jauhiainen M, Paunio T, Lehtimäki T, Salomaa V, Orešič M, Raitakari OT, Ala-Korpela M, Porkka-Heiskanen T.

Sci Rep. 2016 Apr 22;6:24828. doi: 10.1038/srep24828.

15.

Brief Isoflurane Anesthesia Produces Prominent Phosphoproteomic Changes in the Adult Mouse Hippocampus.

Kohtala S, Theilmann W, Suomi T, Wigren HK, Porkka-Heiskanen T, Elo LL, Rokka A, Rantamäki T.

ACS Chem Neurosci. 2016 Jun 15;7(6):749-56. doi: 10.1021/acschemneuro.6b00002. Epub 2016 Apr 28.

PMID:
27074656
16.

Insomnia does not mediate or modify the association between MTNR1B risk variant rs10830963 and glucose levels.

Ollila HM, Kronholm E, Kettunen J, Silander K, Perola M, Porkka-Heiskanen T, Salomaa V, Paunio T.

Diabetologia. 2016 May;59(5):1070-2. doi: 10.1007/s00125-016-3893-8. Epub 2016 Feb 24. No abstract available.

PMID:
26912228
17.

On the Role of Histamine Receptors in the Regulation of Circadian Rhythms.

Rozov SV, Porkka-Heiskanen T, Panula P.

PLoS One. 2015 Dec 10;10(12):e0144694. doi: 10.1371/journal.pone.0144694. eCollection 2015.

18.

Sleep regulatory factors.

Porkka-Heiskanen T.

Arch Ital Biol. 2014 Jun-Sep;152(2-3):57-65. doi: 10.12871/000298292014231. Review.

PMID:
25828678
19.

Cholinergic neurons of the basal forebrain mediate biochemical and electrophysiological mechanisms underlying sleep homeostasis.

Kalinchuk AV, Porkka-Heiskanen T, McCarley RW, Basheer R.

Eur J Neurosci. 2015 Jan;41(2):182-95. doi: 10.1111/ejn.12766. Epub 2014 Nov 4.

20.
21.

Genome-wide association study of sleep duration in the Finnish population.

Ollila HM, Kettunen J, Pietiläinen O, Aho V, Silander K, Kronholm E, Perola M, Lahti J, Räikkönen K, Widen E, Palotie A, Eriksson JG, Partonen T, Kaprio J, Salomaa V, Raitakari O, Lehtimäki T, Sallinen M, Härmä M, Porkka-Heiskanen T, Paunio T.

J Sleep Res. 2014 Dec;23(6):609-618. doi: 10.1111/jsr.12175. Epub 2014 Aug 11.

22.

The relationship between mood and sleep in different female reproductive states.

Toffol E, Kalleinen N, Urrila AS, Himanen SL, Porkka-Heiskanen T, Partonen T, Polo-Kantola P.

BMC Psychiatry. 2014 Jun 16;14:177. doi: 10.1186/1471-244X-14-177.

23.

Amigo adhesion protein regulates development of neural circuits in zebrafish brain.

Zhao X, Kuja-Panula J, Sundvik M, Chen YC, Aho V, Peltola MA, Porkka-Heiskanen T, Panula P, Rauvala H.

J Biol Chem. 2014 Jul 18;289(29):19958-75. doi: 10.1074/jbc.M113.545582. Epub 2014 Jun 5.

24.

Direct activation of the Mauthner cell by electric field pulses drives ultrarapid escape responses.

Tabor KM, Bergeron SA, Horstick EJ, Jordan DC, Aho V, Porkka-Heiskanen T, Haspel G, Burgess HA.

J Neurophysiol. 2014 Aug 15;112(4):834-44. doi: 10.1152/jn.00228.2014. Epub 2014 May 21.

25.

Periodic properties of the histaminergic system of the mouse brain.

Rozov SV, Zant JC, Karlstedt K, Porkka-Heiskanen T, Panula P.

Eur J Neurosci. 2014 Jan;39(2):218-28. doi: 10.1111/ejn.12397. Epub 2013 Nov 6.

PMID:
24438489
26.

Partial sleep restriction activates immune response-related gene expression pathways: experimental and epidemiological studies in humans.

Aho V, Ollila HM, Rantanen V, Kronholm E, Surakka I, van Leeuwen WM, Lehto M, Matikainen S, Ripatti S, Härmä M, Sallinen M, Salomaa V, Jauhiainen M, Alenius H, Paunio T, Porkka-Heiskanen T.

PLoS One. 2013 Oct 23;8(10):e77184. doi: 10.1371/journal.pone.0077184. eCollection 2013.

27.

Sleep, its regulation and possible mechanisms of sleep disturbances.

Porkka-Heiskanen T, Zitting KM, Wigren HK.

Acta Physiol (Oxf). 2013 Aug;208(4):311-28. doi: 10.1111/apha.12134. Epub 2013 Jun 21. Review.

PMID:
23746394
28.

Cholinergic basal forebrain structures are involved in the mediation of the arousal effect of noradrenaline.

Lelkes Z, Porkka-Heiskanen T, Stenberg D.

J Sleep Res. 2013 Dec;22(6):721-6. doi: 10.1111/jsr.12061. Epub 2013 May 24.

29.

Sleep homeostasis.

Porkka-Heiskanen T.

Curr Opin Neurobiol. 2013 Oct;23(5):799-805. doi: 10.1016/j.conb.2013.02.010. Epub 2013 Mar 17. Review.

PMID:
23510741
30.

Effects of cumulative sleep restriction on self-perceptions while multitasking.

Sallinen M, Onninen J, Tirkkonen K, Haavisto ML, Härmä M, Kubo T, Mutanen P, Virkkala J, Tolvanen A, Porkka-Heiskanen T.

J Sleep Res. 2013 Jun;22(3):273-81. doi: 10.1111/jsr.12013. Epub 2012 Nov 22.

31.

Histamine release in the basal forebrain mediates cortical activation through cholinergic neurons.

Zant JC, Rozov S, Wigren HK, Panula P, Porkka-Heiskanen T.

J Neurosci. 2012 Sep 19;32(38):13244-54.

32.

TRIB1 constitutes a molecular link between regulation of sleep and lipid metabolism in humans.

Ollila HM, Utge S, Kronholm E, Aho V, Van Leeuwen W, Silander K, Partonen T, Perola M, Kaprio J, Salomaa V, Sallinen M, Härmä M, Porkka-Heiskanen T, Paunio T.

Transl Psychiatry. 2012 Mar 20;2:e97. doi: 10.1038/tp.2012.20. Review.

33.

Inter-tissue networks between the basal forebrain, hippocampus, and prefrontal cortex in a model for depression caused by disturbed sleep.

Lagus M, Gass N, Saharinen J, Savelyev S, Porkka-Heiskanen T, Paunio T.

J Neurogenet. 2012 Sep;26(3-4):397-412. doi: 10.3109/01677063.2012.694932. Epub 2012 Jul 11.

PMID:
22783900
34.

Sleep homeostasis and depression: studies with the rat clomipramine model of depression.

Savelyev SA, Rantamäki T, Rytkönen KM, Castren E, Porkka-Heiskanen T.

Neuroscience. 2012 Jun 14;212:149-58. doi: 10.1016/j.neuroscience.2012.03.029. Epub 2012 Apr 16.

PMID:
22516018
35.

The temporal relationship between growth hormone and slow wave sleep is weaker after menopause.

Kalleinen N, Virkki A, Polo O, Himanen SL, Irjala K, Joutsen A, Porkka-Heiskanen T, Polo-Kantola P.

Sleep Med. 2012 Jan;13(1):96-101. doi: 10.1016/j.sleep.2011.05.010. Epub 2011 Dec 3.

PMID:
22137103
36.

Shared genetic background for regulation of mood and sleep: association of GRIA3 with sleep duration in healthy Finnish women.

Utge S, Kronholm E, Partonen T, Soronen P, Ollila HM, Loukola A, Perola M, Salomaa V, Porkka-Heiskanen T, Paunio T.

Sleep. 2011 Oct 1;34(10):1309-16. doi: 10.5665/SLEEP.1268.

37.

Automated sleep scoring in rats and mice using the naive Bayes classifier.

Rytkönen KM, Zitting J, Porkka-Heiskanen T.

J Neurosci Methods. 2011 Oct 30;202(1):60-4. doi: 10.1016/j.jneumeth.2011.08.023. Epub 2011 Aug 22.

PMID:
21884727
38.

Increases in extracellular serotonin and dopamine metabolite levels in the basal forebrain during sleep deprivation.

Zant JC, Leenaars CH, Kostin A, Van Someren EJ, Porkka-Heiskanen T.

Brain Res. 2011 Jul 5;1399:40-8. doi: 10.1016/j.brainres.2011.05.008. Epub 2011 May 14.

PMID:
21645878
39.

The time course of adenosine, nitric oxide (NO) and inducible NO synthase changes in the brain with sleep loss and their role in the non-rapid eye movement sleep homeostatic cascade.

Kalinchuk AV, McCarley RW, Porkka-Heiskanen T, Basheer R.

J Neurochem. 2011 Jan;116(2):260-72. doi: 10.1111/j.1471-4159.2010.07100.x. Epub 2010 Dec 2.

40.

Adenosine, energy metabolism and sleep homeostasis.

Porkka-Heiskanen T, Kalinchuk AV.

Sleep Med Rev. 2011 Apr;15(2):123-35. doi: 10.1016/j.smrv.2010.06.005. Epub 2010 Oct 20. Review.

PMID:
20970361
41.

Sleep deprivation triggers inducible nitric oxide-dependent nitric oxide production in wake-active basal forebrain neurons.

Kalinchuk AV, McCarley RW, Porkka-Heiskanen T, Basheer R.

J Neurosci. 2010 Oct 6;30(40):13254-64. doi: 10.1523/JNEUROSCI.0014-10.2010.

42.

Methylxanthines and sleep.

Porkka-Heiskanen T.

Handb Exp Pharmacol. 2011;(200):331-48. doi: 10.1007/978-3-642-13443-2_12. Review.

PMID:
20859802
43.

Prolonged sleep restriction affects glucose metabolism in healthy young men.

van Leeuwen WM, Hublin C, Sallinen M, Härmä M, Hirvonen A, Porkka-Heiskanen T.

Int J Endocrinol. 2010;2010:108641. doi: 10.1155/2010/108641. Epub 2010 Apr 19.

44.

Sleep restriction for the duration of a work week impairs multitasking performance.

Haavisto ML, Porkka-Heiskanen T, Hublin C, Härmä M, Mutanen P, Müller K, Virkkala J, Sallinen M.

J Sleep Res. 2010 Sep;19(3):444-54. doi: 10.1111/j.1365-2869.2010.00823.x. Epub 2010 Apr 9.

45.

Contribution of adenosine related genes to the risk of depression with disturbed sleep.

Gass N, Ollila HM, Utge S, Partonen T, Kronholm E, Pirkola S, Suhonen J, Silander K, Porkka-Heiskanen T, Paunio T.

J Affect Disord. 2010 Oct;126(1-2):134-9. doi: 10.1016/j.jad.2010.03.009. Epub 2010 Apr 13.

PMID:
20392501
46.

Gene expression patterns in a rodent model for depression.

Lagus M, Gass N, Saharinen J, Saarela J, Porkka-Heiskanen T, Paunio T.

Eur J Neurosci. 2010 Apr;31(8):1465-73. doi: 10.1111/j.1460-9568.2010.07166.x. Epub 2010 Apr 6.

PMID:
20384783
47.

Sleep quality and cognitive performance in 8-year-old children.

Paavonen EJ, Räikkönen K, Pesonen AK, Lahti J, Komsi N, Heinonen K, Järvenpää AL, Strandberg T, Kajantie E, Porkka-Heiskanen T.

Sleep Med. 2010 Apr;11(4):386-92. doi: 10.1016/j.sleep.2009.09.009. Epub 2010 Mar 3.

PMID:
20202902
48.

Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance.

Utge SJ, Soronen P, Loukola A, Kronholm E, Ollila HM, Pirkola S, Porkka-Heiskanen T, Partonen T, Paunio T.

PLoS One. 2010 Feb 18;5(2):e9259. doi: 10.1371/journal.pone.0009259.

49.

Sleep-related factors and mobility in older men and women.

Stenholm S, Kronholm E, Sainio P, Borodulin K, Era P, Fogelholm M, Partonen T, Porkka-Heiskanen T, Koskinen S.

J Gerontol A Biol Sci Med Sci. 2010 Jun;65(6):649-57. doi: 10.1093/gerona/glq017. Epub 2010 Feb 16.

50.

Effect of sleep deprivation on multi-unit discharge activity of basal forebrain.

Kostin A, Stenberg D, Porkka-Heiskanen T.

J Sleep Res. 2010 Jun;19(2):269-79. doi: 10.1111/j.1365-2869.2009.00791.x. Epub 2009 Dec 16.

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