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Items: 1 to 50 of 158

1.

The Role of Deimination in Regenerative Reprogramming of Neurons.

Ding D, Enriquez-Algeciras M, Valdivia AO, Torres J, Pole C, Thompson JW, Chou TH, Perez-Pinzon M, Porciatti V, Udin S, Nestler E, Bhattacharya SK.

Mol Neurobiol. 2019 Apr;56(4):2618-2639. doi: 10.1007/s12035-018-1262-y. Epub 2018 Jul 26.

PMID:
30051351
2.

Retinal ganglion cell function in recovered optic neuritis: Faster is not better.

Monsalve P, Ren S, Jiang H, Wang J, Kostic M, Gordon P, Porciatti V.

Clin Neurophysiol. 2018 Sep;129(9):1813-1818. doi: 10.1016/j.clinph.2018.06.012. Epub 2018 Jun 30.

PMID:
29981956
3.

Steady-state PERG adaptation: a conspicuous component of response variability with clinical significance.

Monsalve P, Ren S, Triolo G, Vazquez L, Henderson AD, Kostic M, Gordon P, Feuer WJ, Porciatti V.

Doc Ophthalmol. 2018 Jun;136(3):157-164. doi: 10.1007/s10633-018-9633-2. Epub 2018 May 19.

PMID:
29779071
4.

Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells.

Dvoriantchikova G, Pronin A, Kurtenbach S, Toychiev A, Chou TH, Yee CW, Prindeville B, Tayou J, Porciatti V, Sagdullaev BT, Slepak VZ, Shestopalov VI.

Sci Rep. 2018 Apr 11;8(1):5797. doi: 10.1038/s41598-018-23894-2.

5.

Longterm Reversal of Severe Visual Loss by Mitochondrial Gene Transfer in a Mouse Model of Leber Hereditary Optic Neuropathy.

Yu H, Porciatti V, Lewin A, Hauswirth W, Guy J.

Sci Rep. 2018 Apr 3;8(1):5587. doi: 10.1038/s41598-018-23836-y.

6.

Neurovascular Changes Associated With the Water Drinking Test.

Gameiro G, Monsalve P, Golubev I, Ventura L, Porciatti V.

J Glaucoma. 2018 May;27(5):429-432. doi: 10.1097/IJG.0000000000000898.

7.

Reply.

Guy J, Feuer WJ, Davis JL, Porciatti V, Gonzalez PJ, Koilkonda RD, Yuan H, Hauswirth WW, Lam BL.

Ophthalmology. 2018 Feb;125(2):e15-e16. doi: 10.1016/j.ophtha.2017.08.041. No abstract available.

PMID:
29389414
8.

Anesthetic Preconditioning as Endogenous Neuroprotection in Glaucoma.

Chou TH, Musada GR, Romano GL, Bolton E, Porciatti V.

Int J Mol Sci. 2018 Jan 13;19(1). pii: E237. doi: 10.3390/ijms19010237.

9.

High-Throughput Binocular Pattern Electroretinograms in the Mouse.

Chou TH, Toft-Nielsen J, Porciatti V.

Methods Mol Biol. 2018;1695:63-68. doi: 10.1007/978-1-4939-7407-8_6.

PMID:
29190018
10.

A Novel Mouse Model of Traumatic Optic Neuropathy Using External Ultrasound Energy to Achieve Focal, Indirect Optic Nerve Injury.

Tao W, Dvoriantchikova G, Tse BC, Pappas S, Chou TH, Tapia M, Porciatti V, Ivanov D, Tse DT, Pelaez D.

Sci Rep. 2017 Sep 18;7(1):11779. doi: 10.1038/s41598-017-12225-6.

11.

Gene Therapy for Leber Hereditary Optic Neuropathy: Low- and Medium-Dose Visual Results.

Guy J, Feuer WJ, Davis JL, Porciatti V, Gonzalez PJ, Koilkonda RD, Yuan H, Hauswirth WW, Lam BL.

Ophthalmology. 2017 Nov;124(11):1621-1634. doi: 10.1016/j.ophtha.2017.05.016. Epub 2017 Jun 21.

12.

Next Generation PERG Method: Expanding the Response Dynamic Range and Capturing Response Adaptation.

Monsalve P, Triolo G, Toft-Nielsen J, Bohorquez J, Henderson AD, Delgado R, Miskiel E, Ozdamar O, Feuer WJ, Porciatti V.

Transl Vis Sci Technol. 2017 May 22;6(3):5. doi: 10.1167/tvst.6.3.5. eCollection 2017 May.

13.

Head-down Posture in Glaucoma Suspects Induces Changes in IOP, Systemic Pressure, and PERG That Predict Future Loss of Optic Nerve Tissue.

Porciatti V, Feuer WJ, Monsalve P, Triolo G, Vazquez L, McSoley J, Ventura LM.

J Glaucoma. 2017 May;26(5):459-465. doi: 10.1097/IJG.0000000000000648.

14.

Reply.

Feuer WJ, Guy J, Gonzalez P, Koilkonda R, Porciatti V, Yuan H, Davis JL, Lam BL.

Ophthalmology. 2017 Mar;124(3):e22-e23. doi: 10.1016/j.ophtha.2016.07.003. No abstract available.

PMID:
28219503
15.

Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice.

Williams PA, Harder JM, Foxworth NE, Cochran KE, Philip VM, Porciatti V, Smithies O, John SW.

Science. 2017 Feb 17;355(6326):756-760. doi: 10.1126/science.aal0092.

16.

Integrative properties of retinal ganglion cell electrical responsiveness depend on neurotrophic support and genotype in the mouse.

Chou TH, Feuer WJ, Schwartz O, Rojas MJ, Roebber JK, Porciatti V.

Exp Eye Res. 2016 Apr;145:68-74. doi: 10.1016/j.exer.2015.11.008. Epub 2015 Nov 22.

17.

Gene Therapy for Leber Hereditary Optic Neuropathy: Initial Results.

Feuer WJ, Schiffman JC, Davis JL, Porciatti V, Gonzalez P, Koilkonda RD, Yuan H, Lalwani A, Lam BL, Guy J.

Ophthalmology. 2016 Mar;123(3):558-70. doi: 10.1016/j.ophtha.2015.10.025. Epub 2015 Nov 19.

18.

Consequences of zygote injection and germline transfer of mutant human mitochondrial DNA in mice.

Yu H, Koilkonda RD, Chou TH, Porciatti V, Mehta A, Hentall ID, Chiodo VA, Boye SL, Hauswirth WW, Lewin AS, Guy J.

Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):E5689-98. doi: 10.1073/pnas.1506129112. Epub 2015 Oct 5.

19.

Electrophysiological assessment of retinal ganglion cell function.

Porciatti V.

Exp Eye Res. 2015 Dec;141:164-70. doi: 10.1016/j.exer.2015.05.008. Epub 2015 May 18. Review.

20.

Complex I subunit gene therapy with NDUFA6 ameliorates neurodegeneration in EAE.

Talla V, Koilkonda R, Porciatti V, Chiodo V, Boye SL, Hauswirth WW, Guy J.

Invest Ophthalmol Vis Sci. 2015 Jan 22;56(2):1129-40. doi: 10.1167/iovs.14-15950.

21.

Relationship between transient and steady-state pattern electroretinograms: theoretical and experimental assessment.

Özdamar Ö, Toft-Nielsen J, Bohórquez J, Porciatti V.

Invest Ophthalmol Vis Sci. 2014 Dec 4;55(12):8560-70. doi: 10.1167/iovs.14-15685.

22.

LHON gene therapy vector prevents visual loss and optic neuropathy induced by G11778A mutant mitochondrial DNA: biodistribution and toxicology profile.

Koilkonda R, Yu H, Talla V, Porciatti V, Feuer WJ, Hauswirth WW, Chiodo V, Erger KE, Boye SL, Lewin AS, Conlon TJ, Renner L, Neuringer M, Detrisac C, Guy J.

Invest Ophthalmol Vis Sci. 2014 Oct 23;55(12):7739-53. doi: 10.1167/iovs.14-15388.

23.

Protection of pattern electroretinogram and retinal ganglion cells by oncostatin M after optic nerve injury.

Xia X, Wen R, Chou TH, Li Y, Wang Z, Porciatti V.

PLoS One. 2014 Sep 22;9(9):e108524. doi: 10.1371/journal.pone.0108524. eCollection 2014.

24.
25.

Gene therapy with mitochondrial heat shock protein 70 suppresses visual loss and optic atrophy in experimental autoimmune encephalomyelitis.

Talla V, Porciatti V, Chiodo V, Boye SL, Hauswirth WW, Guy J.

Invest Ophthalmol Vis Sci. 2014 Jul 11;55(8):5214-26. doi: 10.1167/iovs.14-14688.

26.

Robust mouse pattern electroretinograms derived simultaneously from each eye using a common snout electrode.

Chou TH, Bohorquez J, Toft-Nielsen J, Ozdamar O, Porciatti V.

Invest Ophthalmol Vis Sci. 2014 Apr 17;55(4):2469-75. doi: 10.1167/iovs.14-13943.

27.

Trial end points and natural history in patients with G11778A Leber hereditary optic neuropathy : preparation for gene therapy clinical trial.

Lam BL, Feuer WJ, Schiffman JC, Porciatti V, Vandenbroucke R, Rosa PR, Gregori G, Guy J.

JAMA Ophthalmol. 2014 Apr 1;132(4):428-36. doi: 10.1001/jamaophthalmol.2013.7971.

28.

Safety and effects of the vector for the Leber hereditary optic neuropathy gene therapy clinical trial.

Koilkonda RD, Yu H, Chou TH, Feuer WJ, Ruggeri M, Porciatti V, Tse D, Hauswirth WW, Chiodo V, Boye SL, Lewin AS, Neuringer M, Renner L, Guy J.

JAMA Ophthalmol. 2014 Apr 1;132(4):409-20. doi: 10.1001/jamaophthalmol.2013.7630.

29.

Retinal ganglion cell dysfunction in asymptomatic G11778A: Leber hereditary optic neuropathy.

Guy J, Feuer WJ, Porciatti V, Schiffman J, Abukhalil F, Vandenbroucke R, Rosa PR, Lam BL.

Invest Ophthalmol Vis Sci. 2014 Feb 10;55(2):841-8. doi: 10.1167/iovs.13-13365.

30.

NADH-dehydrogenase type-2 suppresses irreversible visual loss and neurodegeneration in the EAE animal model of MS.

Talla V, Yu H, Chou TH, Porciatti V, Chiodo V, Boye SL, Hauswirth WW, Lewin AS, Guy J.

Mol Ther. 2013 Oct;21(10):1876-88. doi: 10.1038/mt.2013.104. Epub 2013 Jun 11.

31.

Noninvasive assessments of optic nerve neurodegeneration in transgenic mice with isolated optic neuritis.

Talla V, Yang C, Shaw G, Porciatti V, Koilkonda RD, Guy J.

Invest Ophthalmol Vis Sci. 2013 Jul 1;54(7):4440-50. doi: 10.1167/iovs.13-11899.

32.

Adaptation of the steady-state PERG in early glaucoma.

Porciatti V, Bosse B, Parekh PK, Shif OA, Feuer WJ, Ventura LM.

J Glaucoma. 2014 Oct-Nov;23(8):494-500. doi: 10.1097/IJG.0b013e318285fd95.

33.

A new mouse model of inducible, chronic retinal ganglion cell dysfunction not associated with cell death.

Yang X, Chou TH, Ruggeri M, Porciatti V.

Invest Ophthalmol Vis Sci. 2013 Mar 28;54(3):1898-904. doi: 10.1167/iovs.12-11375.

34.

Progressive loss of retinal ganglion cell function precedes structural loss by several years in glaucoma suspects.

Banitt MR, Ventura LM, Feuer WJ, Savatovsky E, Luna G, Shif O, Bosse B, Porciatti V.

Invest Ophthalmol Vis Sci. 2013 Mar 28;54(3):2346-52. doi: 10.1167/iovs.12-11026.

35.

Retrograde signaling in the optic nerve is necessary for electrical responsiveness of retinal ganglion cells.

Chou TH, Park KK, Luo X, Porciatti V.

Invest Ophthalmol Vis Sci. 2013 Feb 1;54(2):1236-43. doi: 10.1167/iovs.12-11188.

36.

Deimination restores inner retinal visual function in murine demyelinating disease.

Enriquez-Algeciras M, Ding D, Mastronardi FG, Marc RE, Porciatti V, Bhattacharya SK.

J Clin Invest. 2013 Feb;123(2):646-56. doi: 10.1172/JCI64811. Epub 2013 Jan 2.

37.

Retinal ganglion cell functional plasticity and optic neuropathy: a comprehensive model.

Porciatti V, Ventura LM.

J Neuroophthalmol. 2012 Dec;32(4):354-8. doi: 10.1097/WNO.0b013e3182745600. Review.

38.

The bioelectric field of the pattern electroretinogram in the mouse.

Chou TH, Porciatti V.

Invest Ophthalmol Vis Sci. 2012 Dec 13;53(13):8086-92. doi: 10.1167/iovs.12-10720.

39.

Mutant NADH dehydrogenase subunit 4 gene delivery to mitochondria by targeting sequence-modified adeno-associated virus induces visual loss and optic atrophy in mice.

Yu H, Ozdemir SS, Koilkonda RD, Chou TH, Porciatti V, Chiodo V, Boye SL, Hauswirth WW, Lewin AS, Guy J.

Mol Vis. 2012;18:1668-83. Epub 2012 Jun 20.

40.

Control issues.

Blieden LS, Chen JL, Knape RM, Panarelli JF, Parrish R, Goldberg J, Porciatti V.

Br J Ophthalmol. 2012 Oct;96(10):1348-9. Epub 2012 May 31. No abstract available.

41.

Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber's hereditary optic neuropathy in a mouse model.

Yu H, Koilkonda RD, Chou TH, Porciatti V, Ozdemir SS, Chiodo V, Boye SL, Boye SE, Hauswirth WW, Lewin AS, Guy J.

Proc Natl Acad Sci U S A. 2012 May 15;109(20):E1238-47. doi: 10.1073/pnas.1119577109. Epub 2012 Apr 20.

42.

Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma.

Howell GR, Soto I, Zhu X, Ryan M, Macalinao DG, Sousa GL, Caddle LB, MacNicoll KH, Barbay JM, Porciatti V, Anderson MG, Smith RS, Clark AF, Libby RT, John SW.

J Clin Invest. 2012 Apr;122(4):1246-61. doi: 10.1172/JCI61135. Epub 2012 Mar 19.

43.

Progressive loss of retinal ganglion cell function is hindered with IOP-lowering treatment in early glaucoma.

Ventura LM, Feuer WJ, Porciatti V.

Invest Ophthalmol Vis Sci. 2012 Feb 13;53(2):659-63. doi: 10.1167/iovs.11-8525. Print 2012 Feb.

44.

Head-down posture induces PERG alterations in early glaucoma.

Ventura LM, Golubev I, Lee W, Nose I, Parel JM, Feuer WJ, Porciatti V.

J Glaucoma. 2013 Mar;22(3):255-64. doi: 10.1097/IJG.0b013e318232973b.

45.

Pattern electroretinogram progression in glaucoma suspects.

Ventura LM, Golubev I, Feuer WJ, Porciatti V.

J Glaucoma. 2013 Mar;22(3):219-25. doi: 10.1097/IJG.0b013e318237c89f.

46.

Postnatal elongation of eye size in DBA/2J mice compared with C57BL/6J mice: in vivo analysis with whole-eye OCT.

Chou TH, Kocaoglu OP, Borja D, Ruggeri M, Uhlhorn SR, Manns F, Porciatti V.

Invest Ophthalmol Vis Sci. 2011 Jun 1;52(6):3604-12. doi: 10.1167/iovs.10-6340.

47.

Evaluation of a transgenic mouse model of multiple sclerosis with noninvasive methods.

Enriquez-Algeciras M, Ding D, Chou TH, Wang J, Padgett KR, Porciatti V, Bhattacharya SK.

Invest Ophthalmol Vis Sci. 2011 Apr 14;52(5):2405-11. doi: 10.1167/iovs.10-6425. Print 2011 Apr.

48.
49.

Leber hereditary optic neuropathy gene therapy clinical trial recruitment: year 1.

Lam BL, Feuer WJ, Abukhalil F, Porciatti V, Hauswirth WW, Guy J.

Arch Ophthalmol. 2010 Sep;128(9):1129-35. doi: 10.1001/archophthalmol.2010.201.

50.

Scale for photographic grading of vitreous haze in uveitis.

Davis JL, Madow B, Cornett J, Stratton R, Hess D, Porciatti V, Feuer WJ.

Am J Ophthalmol. 2010 Nov;150(5):637-641.e1. doi: 10.1016/j.ajo.2010.05.036. Epub 2010 Aug 16.

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