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Items: 1 to 50 of 245

1.

The pore structure of Clostridium perfringens epsilon toxin.

Savva CG, Clark AR, Naylor CE, Popoff MR, Moss DS, Basak AK, Titball RW, Bokori-Brown M.

Nat Commun. 2019 Jun 14;10(1):2641. doi: 10.1038/s41467-019-10645-8.

2.

Editorial: Pathogens and disease special issue ETOX18.

Ladant D, Buchrieser C, Popoff MR.

Pathog Dis. 2019 Mar 1;77(2). pii: fty091. doi: 10.1093/femspd/fty091. No abstract available.

PMID:
31029064
3.

Whole-Genome Sequences of a Cluster of 14 Unidentified Related Veillonella sp. Strains from Human Clinical Samples and Type Strains of 3 Veillonella Validated Species.

Aujoulat F, Popoff MR, Diancourt L, Criscuolo A, Jean-Pierre H, Jumas-Bilak E, Marchandin H.

Microbiol Resour Announc. 2019 Mar 21;8(12). pii: e01743-18. doi: 10.1128/MRA.01743-18.

4.

Two Clostridium perfringens Type E Isolates in France.

Diancourt L, Sautereau J, Criscuolo A, Popoff MR.

Toxins (Basel). 2019 Mar 1;11(3). pii: E138. doi: 10.3390/toxins11030138.

5.

Is botulism type C transmissible to human by consumption of contaminated poultry meat? Analysis of a suspect outbreak in French Guyana.

Martrenchar A, Djossou F, Stagnetto C, Dupuy C, Brulez E, Attica C, Egmann G, Gruenfeld J, Fontanella JM, Popoff MR.

Anaerobe. 2019 Apr;56:49-50. doi: 10.1016/j.anaerobe.2019.02.008. Epub 2019 Feb 12.

PMID:
30763675
6.

Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication.

Schnell L, Felix I, Müller B, Sadi M, von Bank F, Papatheodorou P, Popoff MR, Aktories K, Waltenberger E, Benz R, Weichbrodt C, Fauler M, Frick M, Barth H.

FASEB J. 2019 Apr;33(4):5755-5771. doi: 10.1096/fj.201802453R. Epub 2019 Jan 30.

PMID:
30699302
7.

Why Are Botulinum Neurotoxin-Producing Bacteria So Diverse and Botulinum Neurotoxins So Toxic?

Poulain B, Popoff MR.

Toxins (Basel). 2019 Jan 11;11(1). pii: E34. doi: 10.3390/toxins11010034. Review.

8.

Variability of Botulinum Toxins: Challenges and Opportunities for the Future.

Rasetti-Escargueil C, Lemichez E, Popoff MR.

Toxins (Basel). 2018 Sep 13;10(9). pii: E374. doi: 10.3390/toxins10090374. Review.

9.

Clostridium perfringens Enterotoxin: The Toxin Forms Highly Cation-Selective Channels in Lipid Bilayers.

Benz R, Popoff MR.

Toxins (Basel). 2018 Aug 22;10(9). pii: E341. doi: 10.3390/toxins10090341.

10.

Infant botulism: Two case reports and electroneuromyogram findings.

Bernardor J, Neveu J, Haas H, Pitelet G, Popoff MR, Mazuet C, Bérard E, Boulay C, Chabrol B.

Arch Pediatr. 2018 Jun 7. pii: S0929-693X(18)30108-8. doi: 10.1016/j.arcped.2018.05.002. [Epub ahead of print]

PMID:
29887515
11.

Expansion of the Clostridium perfringens toxin-based typing scheme.

Rood JI, Adams V, Lacey J, Lyras D, McClane BA, Melville SB, Moore RJ, Popoff MR, Sarker MR, Songer JG, Uzal FA, Van Immerseel F.

Anaerobe. 2018 Oct;53:5-10. doi: 10.1016/j.anaerobe.2018.04.011. Epub 2018 Apr 20. Review.

PMID:
29866424
12.

Evidence of Clostridium perfringens epsilon toxin associated with multiple sclerosis.

Wagley S, Bokori-Brown M, Morcrette H, Malaspina A, D'Arcy C, Gnanapavan S, Lewis N, Popoff MR, Raciborska D, Nicholas R, Turner B, Titball RW.

Mult Scler. 2019 Apr;25(5):653-660. doi: 10.1177/1352458518767327. Epub 2018 Apr 21.

13.

Human alpha-defensin-1 protects cells from intoxication with Clostridium perfringens iota toxin.

Fischer S, Popoff MR, Barth H.

Pathog Dis. 2018 Mar 1;76(2). doi: 10.1093/femspd/fty022.

PMID:
29635426
14.

Botulinum Neurotoxins: Still a Privilege of Clostridia?

Popoff MR.

Cell Host Microbe. 2018 Feb 14;23(2):145-146. doi: 10.1016/j.chom.2018.01.014.

16.

Development of a clinical prediction score for detection of suspected cases of equine grass sickness (dysautonomia) in France.

Randleff-Rasmussen PK, Leblond A, Cappelle J, Bontemps J, Belluco S, Popoff MR, Marcillaud-Pitel C, Tapprest J, Tritz P, Desjardins I.

Vet Res Commun. 2018 Mar;42(1):19-27. doi: 10.1007/s11259-017-9704-y. Epub 2017 Dec 4.

PMID:
29204821
17.

Clostridium difficile and Clostridium sordellii toxins, proinflammatory versus anti-inflammatory response.

Popoff MR.

Toxicon. 2018 Jul;149:54-64. doi: 10.1016/j.toxicon.2017.11.003. Epub 2017 Nov 14.

PMID:
29146177
18.

ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments.

Wu Y, Pons V, Goudet A, Panigai L, Fischer A, Herweg JA, Kali S, Davey RA, Laporte J, Bouclier C, Yousfi R, Aubenque C, Merer G, Gobbo E, Lopez R, Gillet C, Cojean S, Popoff MR, Clayette P, Le Grand R, Boulogne C, Tordo N, Lemichez E, Loiseau PM, Rudel T, Sauvaire D, Cintrat JC, Gillet D, Barbier J.

Sci Rep. 2017 Nov 14;7(1):15567. doi: 10.1038/s41598-017-15466-7.

19.

A large outbreak of bovine botulism possibly linked to a massive contamination of grass silage by type D/C Clostridium botulinum spores on a farm with dairy and poultry operations.

Relun A, Dorso L, Douart A, Chartier C, Guatteo R, Mazuet C, Popoff MR, Assié S.

Epidemiol Infect. 2017 Dec;145(16):3477-3485. doi: 10.1017/S0950268817002382. Epub 2017 Nov 2.

PMID:
29094676
20.

Translocation and dissemination of botulinum neurotoxin from the intestinal tract.

Fujinaga Y, Popoff MR.

Toxicon. 2018 Jun 1;147:13-18. doi: 10.1016/j.toxicon.2017.10.020. Epub 2017 Oct 24.

PMID:
29074396
21.

The European AntibotABE Framework Program and Its Update: Development of Innovative Botulinum Antibodies.

Rasetti-Escargueil C, Avril A, Miethe S, Mazuet C, Derman Y, Selby K, Thullier P, Pelat T, Urbain R, Fontayne A, Korkeala H, Sesardic D, Hust M, Popoff MR.

Toxins (Basel). 2017 Oct 2;9(10). pii: E309. doi: 10.3390/toxins9100309. Review.

22.

Uptake of Clostridial Neurotoxins into Cells and Dissemination.

Connan C, Popoff MR.

Curr Top Microbiol Immunol. 2017;406:39-78. doi: 10.1007/82_2017_50. Review.

PMID:
28879524
23.

Highly sensitive sandwich immunoassay and immunochromatographic test for the detection of Clostridial epsilon toxin in complex matrices.

Féraudet-Tarisse C, Mazuet C, Pauillac S, Krüger M, Lacroux C, Popoff MR, Dorner BG, Andréoletti O, Plaisance M, Volland H, Simon S.

PLoS One. 2017 Jul 11;12(7):e0181013. doi: 10.1371/journal.pone.0181013. eCollection 2017.

24.

Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells.

Ernst K, Schmid J, Beck M, Hägele M, Hohwieler M, Hauff P, Ückert AK, Anastasia A, Fauler M, Jank T, Aktories K, Popoff MR, Schiene-Fischer C, Kleger A, Müller M, Frick M, Barth H.

Sci Rep. 2017 Jun 2;7(1):2724. doi: 10.1038/s41598-017-02882-y.

25.

Botulinum neurotoxin type B uses a distinct entry pathway mediated by CDC42 into intestinal cells versus neuronal cells.

Connan C, Voillequin M, Chavez CV, Mazuet C, Leveque C, Vitry S, Vandewalle A, Popoff MR.

Cell Microbiol. 2017 Aug;19(8). doi: 10.1111/cmi.12738. Epub 2017 Apr 10.

26.

Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature.

Peck MW, Smith TJ, Anniballi F, Austin JW, Bano L, Bradshaw M, Cuervo P, Cheng LW, Derman Y, Dorner BG, Fisher A, Hill KK, Kalb SR, Korkeala H, Lindström M, Lista F, Lúquez C, Mazuet C, Pirazzini M, Popoff MR, Rossetto O, Rummel A, Sesardic D, Singh BR, Stringer SC.

Toxins (Basel). 2017 Jan 18;9(1). pii: E38. doi: 10.3390/toxins9010038. Review.

27.

First isolation of Clostridium indolis in a patient with chronic osteitis: a case report and literature review of human infections related to Clostridium saccharolyticum group species.

Lotte R, Lotte L, Bouvet P, Degand N, Bal A, Carles M, de Dompsure RB, Popoff MR, Ruimy R.

Anaerobe. 2016 Dec;42:44-49. doi: 10.1016/j.anaerobe.2016.08.001. Epub 2016 Aug 7.

28.

Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B.

Miethe S, Mazuet C, Liu Y, Tierney R, Rasetti-Escargueil C, Avril A, Frenzel A, Thullier P, Pelat T, Urbain R, Fontayne A, Sesardic D, Hust M, Popoff MR.

PLoS One. 2016 Aug 25;11(8):e0161446. doi: 10.1371/journal.pone.0161446. eCollection 2016.

29.

Diversity of Group I and II Clostridium botulinum Strains from France Including Recently Identified Subtypes.

Mazuet C, Legeay C, Sautereau J, Ma L, Bouchier C, Bouvet P, Popoff MR.

Genome Biol Evol. 2016 Jun 13;8(6):1643-60. doi: 10.1093/gbe/evw101.

30.

A penicillin- and metronidazole-resistant Clostridium botulinum strain responsible for an infant botulism case.

Mazuet C, Yoon EJ, Boyer S, Pignier S, Blanc T, Doehring I, Meziane-Cherif D, Dumant-Forest C, Sautereau J, Legeay C, Bouvet P, Bouchier C, Quijano-Roy S, Pestel-Caron M, Courvalin P, Popoff MR.

Clin Microbiol Infect. 2016 Jul;22(7):644.e7-644.e12. doi: 10.1016/j.cmi.2016.04.011. Epub 2016 Apr 21.

31.

EGA Protects Mammalian Cells from Clostridium difficile CDT, Clostridium perfringens Iota Toxin and Clostridium botulinum C2 Toxin.

Schnell L, Mittler AK, Sadi M, Popoff MR, Schwan C, Aktories K, Mattarei A, Azarnia Tehran D, Montecucco C, Barth H.

Toxins (Basel). 2016 Apr 1;8(4):101. doi: 10.3390/toxins8040101.

32.

The Tip of the Four N-Terminal α-Helices of Clostridium sordellii Lethal Toxin Contains the Interaction Site with Membrane Phosphatidylserine Facilitating Small GTPases Glucosylation.

Varela Chavez C, Haustant GM, Baron B, England P, Chenal A, Pauillac S, Blondel A, Popoff MR.

Toxins (Basel). 2016 Mar 25;8(4):90. doi: 10.3390/toxins8040090.

33.

Special Issue on "Toxins: New targets and new functions".

Benoit E, Barbier J, Popoff MR, Faure G, Molgó J, Servent D.

Toxicon. 2016 Jun 15;116:1-3. doi: 10.1016/j.toxicon.2016.03.012. Epub 2016 Mar 17. No abstract available.

PMID:
26996493
34.

A cluster of three cases of botulism due to Clostridium baratii type F, France, August 2015.

Tréhard H, Poujol I, Mazuet C, Blanc Q, Gillet Y, Rossignol F, Popoff MR, Jourdan Da Silva N.

Euro Surveill. 2016;21(4). doi: 10.2807/1560-7917.ES.2016.21.4.30117.

35.

A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin.

Ernst K, Liebscher M, Mathea S, Granzhan A, Schmid J, Popoff MR, Ihmels H, Barth H, Schiene-Fischer C.

Sci Rep. 2016 Feb 3;6:20301. doi: 10.1038/srep20301.

36.

An optical biosensor assay for rapid dual detection of Botulinum neurotoxins A and E.

Lévêque C, Ferracci G, Maulet Y, Mazuet C, Popoff MR, Blanchard MP, Seagar M, El Far O.

Sci Rep. 2015 Dec 9;5:17953. doi: 10.1038/srep17953.

37.

Development of Human-Like scFv-Fc Neutralizing Botulinum Neurotoxin E.

Miethe S, Rasetti-Escargueil C, Avril A, Liu Y, Chahboun S, Korkeala H, Mazuet C, Popoff MR, Pelat T, Thullier P, Sesardic D, Hust M.

PLoS One. 2015 Oct 6;10(10):e0139905. doi: 10.1371/journal.pone.0139905. eCollection 2015.

38.

Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A1 and A2 by targeting their heavy chain.

Avril A, Miethe S, Popoff MR, Mazuet C, Chahboun S, Rasetti-Escargueil C, Sesardic D, Thullier P, Hust M, Pelat T.

BMC Biotechnol. 2015 Sep 17;15:86. doi: 10.1186/s12896-015-0206-0.

39.

Development of human-like scFv-Fc antibodies neutralizing Botulinum toxin serotype B.

Rasetti-Escargueil C, Avril A, Chahboun S, Tierney R, Bak N, Miethe S, Mazuet C, Popoff MR, Thullier P, Hust M, Pelat T, Sesardic D.

MAbs. 2015;7(6):1161-77. doi: 10.1080/19420862.2015.1082016. Epub 2015 Sep 18.

40.

Translocation and dissemination to target neurons of botulinum neurotoxin type B in the mouse intestinal wall.

Connan C, Varela-Chavez C, Mazuet C, Molgó J, Haustant GM, Disson O, Lecuit M, Vandewalle A, Popoff MR.

Cell Microbiol. 2016 Feb;18(2):282-301. doi: 10.1111/cmi.12502. Epub 2015 Sep 18.

41.

Pore-forming activity of clostridial binary toxins.

Knapp O, Benz R, Popoff MR.

Biochim Biophys Acta. 2016 Mar;1858(3):512-25. doi: 10.1016/j.bbamem.2015.08.006. Epub 2015 Aug 14. Review.

42.

Characterization of botulinum neurotoxin type A subtypes by immunocapture enrichment and liquid chromatography-tandem mass spectrometry.

Morineaux V, Mazuet C, Hilaire D, Enche J, Popoff MR.

Anal Bioanal Chem. 2015 Jul;407(19):5559-70. doi: 10.1007/s00216-015-8707-1. Epub 2015 Jun 3.

43.

The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid.

Varela Chavez C, Hoos S, Haustant GM, Chenal A, England P, Blondel A, Pauillac S, Lacy DB, Popoff MR.

Cell Microbiol. 2015 Oct;17(10):1477-93. doi: 10.1111/cmi.12449. Epub 2015 May 13.

PMID:
25882477
44.

Draft Genome Sequence of Clostridium botulinum Strain 277-00 Type B2.

Mazuet C, Bouchier C, Popoff MR.

Genome Announc. 2015 Apr 2;3(2). pii: e00211-15. doi: 10.1128/genomeA.00211-15.

45.

A vanG-type locus in Clostridium argentinense.

Berthet N, Périchon B, Mazuet C, Chapetón-Montes D, Bouchier C, Bouvet P, Legeay C, Popoff MR, Courvalin P.

J Antimicrob Chemother. 2015 Jul;70(7):1942-5. doi: 10.1093/jac/dkv073. Epub 2015 Mar 22.

PMID:
25802283
46.

From saprophytic to toxigenic clostridia, a complex evolution based on multiple diverse genetic transfers and/or rearrangements.

Popoff MR.

Res Microbiol. 2015 May;166(4):221-4. doi: 10.1016/j.resmic.2015.02.008. Epub 2015 Mar 2. Review. No abstract available.

PMID:
25744779
47.

Cluster of two cases of botulism due to Clostridium baratii type F in France, November 2014.

Castor C, Mazuet C, Saint-Leger M, Vygen S, Coutureau J, Durand M, Popoff MR, Jourdan Da Silva N.

Euro Surveill. 2015 Feb 12;20(6). pii: 21031.

48.

Genomics of Clostridium tetani.

Brüggemann H, Brzuszkiewicz E, Chapeton-Montes D, Plourde L, Speck D, Popoff MR.

Res Microbiol. 2015 May;166(4):326-31. doi: 10.1016/j.resmic.2015.01.002. Epub 2015 Jan 29.

49.

Foot infection by Clostridium sordellii: case report and review of 15 cases in France.

Bouvet P, Sautereau J, Le Coustumier A, Mory F, Bouchier C, Popoff MR.

J Clin Microbiol. 2015 Apr;53(4):1423-7. doi: 10.1128/JCM.03414-14. Epub 2015 Jan 21.

50.

Two-component systems and toxinogenesis regulation in Clostridium botulinum.

Connan C, Popoff MR.

Res Microbiol. 2015 May;166(4):332-43. doi: 10.1016/j.resmic.2014.12.012. Epub 2015 Jan 12. Review.

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