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Items: 1 to 50 of 155

1.

Serotonin transporter deficiency alters socioemotional ultrasonic communication in rats.

Golebiowska J, Hołuj M, Potasiewicz A, Piotrowska D, Kuziak A, Popik P, Homberg JR, Nikiforuk A.

Sci Rep. 2019 Dec 30;9(1):20283. doi: 10.1038/s41598-019-56629-y.

2.

Cannabidiol Improves Cognitive Impairment and Reverses Cortical Transcriptional Changes Induced by Ketamine, in Schizophrenia-Like Model in Rats.

Kozela E, Krawczyk M, Kos T, Juknat A, Vogel Z, Popik P.

Mol Neurobiol. 2019 Dec 11. doi: 10.1007/s12035-019-01831-2. [Epub ahead of print]

PMID:
31823199
3.

Behavioral effects of buspirone in a mouse model of posttraumatic stress disorder.

Malikowska-Racia N, Popik P, Sałat K.

Behav Brain Res. 2019 Nov 22:112380. doi: 10.1016/j.bbr.2019.112380. [Epub ahead of print]

PMID:
31765726
4.

Virtual screening-driven discovery of dual 5-HT6/5-HT2A receptor ligands with pro-cognitive properties.

Staroń J, Kurczab R, Warszycki D, Satała G, Krawczyk M, Bugno R, Lenda T, Popik P, Hogendorf AS, Hogendorf A, Dubiel K, Matłoka M, Moszczyński-Pętkowski R, Pieczykolan J, Wieczorek M, Zajdel P, Bojarski AJ.

Eur J Med Chem. 2020 Jan 1;185:111857. doi: 10.1016/j.ejmech.2019.111857. Epub 2019 Nov 7.

5.

Serotonin type 5A receptor antagonists inhibit D-lysergic acid diethylamide discriminatory cue in rats.

Popik P, Krawczyk M, Kuziak A, Bugno R, Hogendorf A, Staroń J, Nikiforuk A.

J Psychopharmacol. 2019 Nov;33(11):1447-1455. doi: 10.1177/0269881119867603. Epub 2019 Aug 27.

PMID:
31452444
6.

2-Aminoimidazole-based antagonists of the 5-HT6 receptor - A new concept in aminergic GPCR ligand design.

Hogendorf AS, Hogendorf A, Kurczab R, Kalinowska-Tłuścik J, Popik P, Nikiforuk A, Krawczyk M, Satała G, Lenda T, Knutelska J, Bugno R, Staroń J, Pietruś W, Matłoka M, Dubiel K, Moszczyński-Pętkowski R, Pieczykolan J, Wieczorek M, Pilarski B, Zajdel P, Bojarski AJ.

Eur J Med Chem. 2019 Oct 1;179:1-15. doi: 10.1016/j.ejmech.2019.06.001. Epub 2019 Jun 5.

PMID:
31229883
7.

Dopamine D2/D3 receptor agonists attenuate PTSD-like symptoms in mice exposed to single prolonged stress.

Malikowska-Racia N, Sałat K, Nowaczyk A, Fijałkowski Ł, Popik P.

Neuropharmacology. 2019 Sep 1;155:1-9. doi: 10.1016/j.neuropharm.2019.05.012. Epub 2019 May 11.

PMID:
31085186
8.

Dual 5-HT6 and D3 Receptor Antagonists in a Group of 1H-Pyrrolo[3,2-c]quinolines with Neuroprotective and Procognitive Activity.

Grychowska K, Chaumont-Dubel S, Kurczab R, Koczurkiewicz P, Deville C, Krawczyk M, Pietruś W, Satała G, Buda S, Piska K, Drop M, Bantreil X, Lamaty F, Pękala E, Bojarski AJ, Popik P, Marin P, Zajdel P.

ACS Chem Neurosci. 2019 Jul 17;10(7):3183-3196. doi: 10.1021/acschemneuro.8b00618. Epub 2019 Apr 2.

PMID:
30896921
9.

Procognitive effects of varenicline in the animal model of schizophrenia depend on α4β2- and α 7-nicotinic acetylcholine receptors.

Potasiewicz A, Golebiowska J, Popik P, Nikiforuk A.

J Psychopharmacol. 2018 Dec 3;33(1):269881118812097. doi: 10.1177/0269881118812097.

PMID:
30501536
10.

Evaluation of ultrasonic vocalizations in a neurodevelopmental model of schizophrenia during the early life stages of rats.

Potasiewicz A, Holuj M, Piotrowska D, Zajda K, Wojcik M, Popik P, Nikiforuk A.

Neuropharmacology. 2019 Mar 1;146:28-38. doi: 10.1016/j.neuropharm.2018.11.023. Epub 2018 Nov 15.

PMID:
30448422
11.

Enhanced pharmacological efficacy of sumatriptan due to modification of its physicochemical properties by inclusion in selected cyclodextrins.

Paczkowska M, Mizera M, Sałat K, Furgała A, Popik P, Knapik-Kowalczuk J, Krause A, Szymanowska-Powałowska D, Fojud Z, Kozak M, Paluch M, Cielecka-Piontek J.

Sci Rep. 2018 Nov 1;8(1):16184. doi: 10.1038/s41598-018-34554-w.

12.

Novel multi-target azinesulfonamides of cyclic amine derivatives as potential antipsychotics with pro-social and pro-cognitive effects.

Zajdel P, Kos T, Marciniec K, Satała G, Canale V, Kamiński K, Hołuj M, Lenda T, Koralewski R, Bednarski M, Nowiński L, Wójcikowski J, Daniel WA, Nikiforuk A, Nalepa I, Chmielarz P, Kuśmierczyk J, Bojarski AJ, Popik P.

Eur J Med Chem. 2018 Feb 10;145:790-804. doi: 10.1016/j.ejmech.2018.01.002. Epub 2018 Jan 3.

PMID:
29407591
13.

Novel non-sulfonamide 5-HT6 receptor partial inverse agonist in a group of imidazo[4,5-b]pyridines with cognition enhancing properties.

Vanda D, Soural M, Canale V, Chaumont-Dubel S, Satała G, Kos T, Funk P, Fülöpová V, Lemrová B, Koczurkiewicz P, Pękala E, Bojarski AJ, Popik P, Marin P, Zajdel P.

Eur J Med Chem. 2018 Jan 20;144:716-729. doi: 10.1016/j.ejmech.2017.12.053. Epub 2017 Dec 16.

PMID:
29291439
14.

A Novel Dopamine Transporter Inhibitor CE-123 Improves Cognitive Flexibility and Maintains Impulsivity in Healthy Male Rats.

Nikiforuk A, Kalaba P, Ilic M, Korz V, Dragačević V, Wackerlig J, Langer T, Höger H, Golebiowska J, Popik P, Lubec G.

Front Behav Neurosci. 2017 Nov 27;11:222. doi: 10.3389/fnbeh.2017.00222. eCollection 2017.

15.

Antidepressant-like activity of venlafaxine and clonidine in mice exposed to single prolonged stress - A model of post-traumatic stress disorder. Pharmacodynamic and molecular docking studies.

Malikowska N, Fijałkowski Ł, Nowaczyk A, Popik P, Sałat K.

Brain Res. 2017 Oct 15;1673:1-10. doi: 10.1016/j.brainres.2017.08.001. Epub 2017 Aug 8.

PMID:
28797691
16.

Comparison of the Psychopharmacological Effects of Tiletamine and Ketamine in Rodents.

Popik P, Hołuj M, Kos T, Nowak G, Librowski T, Sałat K.

Neurotox Res. 2017 Nov;32(4):544-554. doi: 10.1007/s12640-017-9759-0. Epub 2017 Jun 2.

17.

Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in a ketamine-based animal model of schizophrenia.

Zurawek D, Salerno-Kochan A, Dziedzicka-Wasylewska M, Nikiforuk A, Kos T, Popik P.

Schizophr Res. 2018 Feb;192:423-430. doi: 10.1016/j.schres.2017.04.014. Epub 2017 Apr 20.

PMID:
28433499
18.

Novel 5-HT7R antagonists, arylsulfonamide derivatives of (aryloxy)propyl piperidines: Add-on effect to the antidepressant activity of SSRI and DRI, and pro-cognitive profile.

Canale V, Partyka A, Kurczab R, Krawczyk M, Kos T, Satała G, Kubica B, Jastrzębska-Więsek M, Wesołowska A, Bojarski AJ, Popik P, Zajdel P.

Bioorg Med Chem. 2017 May 15;25(10):2789-2799. doi: 10.1016/j.bmc.2017.03.057. Epub 2017 Mar 29.

PMID:
28391970
19.

Stimulation of nicotinic acetylcholine alpha7 receptors rescue schizophrenia-like cognitive impairments in rats.

Potasiewicz A, Nikiforuk A, Hołuj M, Popik P.

J Psychopharmacol. 2017 Feb;31(2):260-271. doi: 10.1177/0269881116675509. Epub 2016 Nov 15.

PMID:
28168926
20.

3-Furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic receptor, reverses schizophrenia-like cognitive and social deficits in rats.

Potasiewicz A, Hołuj M, Kos T, Popik P, Arias HR, Nikiforuk A.

Neuropharmacology. 2017 Feb;113(Pt A):188-197. doi: 10.1016/j.neuropharm.2016.10.002. Epub 2016 Oct 4.

PMID:
27717880
21.

Retraction notice to "Dopamine induces an optimism bias in rats - Pharmacological proof for the translational validity of the ambiguous-cue interpretation test" [Behav. Brain Res. 297 (2016) 84-90].

Kregiel J, Golebiowska J, Popik P, Rygula R.

Behav Brain Res. 2017 Jan 1;316:305. doi: 10.1016/j.bbr.2016.09.046. No abstract available.

PMID:
27692284
22.

The combination of memantine and galantamine improves cognition in rats: The synergistic role of the α7 nicotinic acetylcholine and NMDA receptors.

Nikiforuk A, Potasiewicz A, Kos T, Popik P.

Behav Brain Res. 2016 Oct 15;313:214-218. doi: 10.1016/j.bbr.2016.07.023. Epub 2016 Jul 18.

PMID:
27435422
23.

N1-Azinylsulfonyl-1H-indoles: 5-HT6 Receptor Antagonists with Procognitive and Antidepressant-Like Properties.

Zajdel P, Marciniec K, Satała G, Canale V, Kos T, Partyka A, Jastrzębska-Więsek M, Wesołowska A, Basińska-Ziobroń A, Wójcikowski J, Daniel WA, Bojarski AJ, Popik P.

ACS Med Chem Lett. 2016 Apr 7;7(6):618-22. doi: 10.1021/acsmedchemlett.6b00056. eCollection 2016 Jun 9.

24.

Novel 1H-Pyrrolo[3,2-c]quinoline Based 5-HT6 Receptor Antagonists with Potential Application for the Treatment of Cognitive Disorders Associated with Alzheimer's Disease.

Grychowska K, Satała G, Kos T, Partyka A, Colacino E, Chaumont-Dubel S, Bantreil X, Wesołowska A, Pawłowski M, Martinez J, Marin P, Subra G, Bojarski AJ, Lamaty F, Popik P, Zajdel P.

ACS Chem Neurosci. 2016 Jul 20;7(7):972-83. doi: 10.1021/acschemneuro.6b00090. Epub 2016 May 5.

PMID:
27100049
25.

Trait "pessimism" is associated with increased sensitivity to negative feedback in rats.

Rygula R, Popik P.

Cogn Affect Behav Neurosci. 2016 Jun;16(3):516-26. doi: 10.3758/s13415-016-0410-y.

PMID:
26902303
26.

The effects of a 5-HT5A receptor antagonist in a ketamine-based rat model of cognitive dysfunction and the negative symptoms of schizophrenia.

Nikiforuk A, Hołuj M, Kos T, Popik P.

Neuropharmacology. 2016 Jun;105:351-360. doi: 10.1016/j.neuropharm.2016.01.035. Epub 2016 Jan 28.

PMID:
26826431
27.

N-Alkylated arylsulfonamides of (aryloxy)ethyl piperidines: 5-HT(7) receptor selectivity versus multireceptor profile.

Canale V, Kurczab R, Partyka A, Satała G, Słoczyńska K, Kos T, Jastrzębska-Więsek M, Siwek A, Pękala E, Bojarski AJ, Wesołowska A, Popik P, Zajdel P.

Bioorg Med Chem. 2016 Jan 15;24(2):130-9. doi: 10.1016/j.bmc.2015.11.041. Epub 2015 Nov 30.

PMID:
26706111
28.

Effects of optimism on gambling in the rat slot machine task.

Rafa D, Kregiel J, Popik P, Rygula R.

Behav Brain Res. 2016 Mar 1;300:97-105. doi: 10.1016/j.bbr.2015.12.013. Epub 2015 Dec 14.

PMID:
26698397
29.

The effects of PDE10 inhibition on attentional set-shifting do not depend on the activation of dopamine D1 receptors.

Nikiforuk A, Potasiewicz A, Rafa D, Drescher K, Bespalov A, Popik P.

Behav Pharmacol. 2016 Jun;27(4):331-8. doi: 10.1097/FBP.0000000000000201.

PMID:
26580130
30.

Dopamine induces an optimism bias in rats-Pharmacological proof for the translational validity of the ambiguous-cue interpretation test.

Kregiel J, Golebiowska J, Popik P, Rygula R.

Behav Brain Res. 2016 Jan 15;297:84-90. doi: 10.1016/j.bbr.2015.10.020. Epub 2015 Oct 14. Retraction in: Behav Brain Res. 2017 Jan 1;316:305.

PMID:
26462571
31.

Anandamide mediates cognitive judgement bias in rats.

Kregiel J, Malek N, Popik P, Starowicz K, Rygula R.

Neuropharmacology. 2016 Feb;101:146-53. doi: 10.1016/j.neuropharm.2015.09.009. Epub 2015 Sep 9.

PMID:
26363193
32.

Pro-cognitive activity in rats of 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic acetylcholine receptor.

Potasiewicz A, Kos T, Ravazzini F, Puia G, Arias HR, Popik P, Nikiforuk A.

Br J Pharmacol. 2015 Nov;172(21):5123-35. doi: 10.1111/bph.13277. Epub 2015 Oct 10. Erratum in: Br J Pharmacol. 2016 Jan;173(2):411.

33.

Antidepressant-like effects of ketamine, norketamine and dehydronorketamine in forced swim test: Role of activity at NMDA receptor.

Sałat K, Siwek A, Starowicz G, Librowski T, Nowak G, Drabik U, Gajdosz R, Popik P.

Neuropharmacology. 2015 Dec;99:301-7. doi: 10.1016/j.neuropharm.2015.07.037. Epub 2015 Aug 1.

PMID:
26240948
34.

Positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors reverse ketamine-induced schizophrenia-like deficits in rats.

Nikiforuk A, Kos T, Hołuj M, Potasiewicz A, Popik P.

Neuropharmacology. 2016 Feb;101:389-400. doi: 10.1016/j.neuropharm.2015.07.034. Epub 2015 Jul 29.

PMID:
26232639
35.

Attentional Set-Shifting Paradigm in the Rat.

Popik P, Nikiforuk A.

Curr Protoc Neurosci. 2015 Jul 1;72:9.51.1-9.51.13. doi: 10.1002/0471142301.ns0951s72.

PMID:
26131663
36.

Positive allosteric modulation of alpha 7 nicotinic acetylcholine receptors enhances recognition memory and cognitive flexibility in rats.

Nikiforuk A, Kos T, Potasiewicz A, Popik P.

Eur Neuropsychopharmacol. 2015 Aug;25(8):1300-13. doi: 10.1016/j.euroneuro.2015.04.018. Epub 2015 Apr 30.

PMID:
26003081
37.

Effects of the selective 5-HT7 receptor antagonist SB-269970 on premature responding in the five-choice serial reaction time test in rats.

Nikiforuk A, Hołuj M, Potasiewicz A, Popik P.

Behav Brain Res. 2015 Aug 1;289:149-56. doi: 10.1016/j.bbr.2015.04.030. Epub 2015 Apr 27.

PMID:
25930219
38.

Effect of NMDAR antagonists in the tetrabenazine test for antidepressants: comparison with the tail suspension test.

Skolnick P, Kos T, Czekaj J, Popik P.

Acta Neuropsychiatr. 2015 Aug;27(4):228-34. doi: 10.1017/neu.2015.14. Epub 2015 Apr 10.

PMID:
25858023
39.

Improvement of ketamine-induced social withdrawal in rats: the role of 5-HT7 receptors.

Hołuj M, Popik P, Nikiforuk A.

Behav Pharmacol. 2015 Dec;26(8 Spec No):766-75. doi: 10.1097/FBP.0000000000000132.

PMID:
25769091
40.

Effects of optimism on motivation in rats.

Rygula R, Golebiowska J, Kregiel J, Kubik J, Popik P.

Front Behav Neurosci. 2015 Feb 25;9:32. doi: 10.3389/fnbeh.2015.00032. eCollection 2015.

41.

Acute administration of lithium, but not valproate, modulates cognitive judgment bias in rats.

Rygula R, Golebiowska J, Kregiel J, Holuj M, Popik P.

Psychopharmacology (Berl). 2015 Jun;232(12):2149-56. doi: 10.1007/s00213-014-3847-0. Epub 2014 Dec 25.

42.

1-aminocyclopropanecarboxylic acid (ACPC) produces procognitive but not antipsychotic-like effects in rats.

Popik P, Holuj M, Nikiforuk A, Kos T, Trullas R, Skolnick P.

Psychopharmacology (Berl). 2015 Mar;232(6):1025-38. doi: 10.1007/s00213-014-3738-4. Epub 2014 Sep 27.

43.

Cognitive judgment bias in the psychostimulant-induced model of mania in rats.

Rygula R, Szczech E, Kregiel J, Golebiowska J, Kubik J, Popik P.

Psychopharmacology (Berl). 2015 Feb;232(3):651-60. doi: 10.1007/s00213-014-3707-y. Epub 2014 Aug 14.

44.

The effects of cocaine and mazindol on the cognitive judgement bias of rats in the ambiguous-cue interpretation paradigm.

Rygula R, Szczech E, Papciak J, Nikiforuk A, Popik P.

Behav Brain Res. 2014 Aug 15;270:206-12. doi: 10.1016/j.bbr.2014.05.026. Epub 2014 May 23.

PMID:
24859175
45.

The effects of acute and repeated administration of ketamine on attentional performance in the five-choice serial reaction time task in rats.

Nikiforuk A, Popik P.

Eur Neuropsychopharmacol. 2014 Aug;24(8):1381-93. doi: 10.1016/j.euroneuro.2014.04.007. Epub 2014 May 4.

PMID:
24846536
46.

Prediction of Young׳s modulus of trabeculae in microscale using macro-scale׳s relationships between bone density and mechanical properties.

Cyganik Ł, Binkowski M, Kokot G, Rusin T, Popik P, Bolechała F, Nowak R, Wróbel Z, John A.

J Mech Behav Biomed Mater. 2014 Aug;36:120-34. doi: 10.1016/j.jmbbm.2014.04.011. Epub 2014 Apr 29.

47.
48.

The effects of acute pharmacological stimulation of the 5-HT, NA and DA systems on the cognitive judgement bias of rats in the ambiguous-cue interpretation paradigm.

Rygula R, Papciak J, Popik P.

Eur Neuropsychopharmacol. 2014 Jul;24(7):1103-11. doi: 10.1016/j.euroneuro.2014.01.012. Epub 2014 Jan 18.

PMID:
24503278
49.

Ketamine prevents stress-induced cognitive inflexibility in rats.

Nikiforuk A, Popik P.

Psychoneuroendocrinology. 2014 Feb;40:119-22. doi: 10.1016/j.psyneuen.2013.11.009. Epub 2013 Nov 20.

PMID:
24485483
50.

Conditioned rewarding effects of morphine and methadone in mice pre-exposed to cocaine.

Hołuj M, Bisaga A, Popik P.

Pharmacol Rep. 2013;65(5):1176-84.

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