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Items: 1 to 50 of 198

1.

Leishmania major degrades murine CXCL1 - An immune evasion strategy.

Yorek MS, Poudel B, Mazgaeen L, Pope RM, Wilson ME, Gurung P.

PLoS Negl Trop Dis. 2019 Jul 1;13(7):e0007533. doi: 10.1371/journal.pntd.0007533. eCollection 2019 Jul.

2.

Communicating, consulting, and caring differently.

Pope RM, Ali SM, Muir CD, Schulte AA.

BMJ. 2018 Jul 13;362:k3103. doi: 10.1136/bmj.k3103. No abstract available.

PMID:
30006477
3.

Extracellular release of virulence factor major surface protease via exosomes in Leishmania infantum promastigotes.

Marshall S, Kelly PH, Singh BK, Pope RM, Kim P, Zhanbolat B, Wilson ME, Yao C.

Parasit Vectors. 2018 Jun 19;11(1):355. doi: 10.1186/s13071-018-2937-y.

4.

Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis.

Mandelin AM 2nd, Homan PJ, Shaffer AM, Cuda CM, Dominguez ST, Bacalao E, Carns M, Hinchcliff M, Lee J, Aren K, Thakrar A, Montgomery AB, Bridges SL Jr, Bathon JM, Atkinson JP, Fox DA, Matteson EL, Buckley CD, Pitzalis C, Parks D, Hughes LB, Geraldino-Pardilla L, Ike R, Phillips K, Wright K, Filer A, Kelly S, Ruderman EM, Morgan V, Abdala-Valencia H, Misharin AV, Budinger GS, Bartom ET, Pope RM, Perlman H, Winter DR.

Arthritis Rheumatol. 2018 Jun;70(6):841-854. doi: 10.1002/art.40453. Epub 2018 May 3.

5.

Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR-Knockout Ferrets.

Rosen BH, Evans TIA, Moll SR, Gray JS, Liang B, Sun X, Zhang Y, Jensen-Cody CW, Swatek AM, Zhou W, He N, Rotti PG, Tyler SR, Keiser NW, Anderson PJ, Brooks L, Li Y, Pope RM, Rajput M, Hoffman EA, Wang K, Harris JK, Parekh KR, Gibson-Corley KN, Engelhardt JF.

Am J Respir Crit Care Med. 2018 May 15;197(10):1308-1318. doi: 10.1164/rccm.201708-1616OC.

6.

The Role of Macrophages in the Response to TNF Inhibition in Experimental Arthritis.

Huang QQ, Birkett R, Doyle R, Shi B, Roberts EL, Mao Q, Pope RM.

J Immunol. 2018 Jan 1;200(1):130-138. doi: 10.4049/jimmunol.1700229. Epub 2017 Nov 17.

7.

Association of Increased F4/80high Macrophages With Suppression of Serum-Transfer Arthritis in Mice With Reduced FLIP in Myeloid Cells.

Huang QQ, Birkett R, Doyle RE, Haines GK, Perlman H, Shi B, Homan P, Xing L, Pope RM.

Arthritis Rheumatol. 2017 Sep;69(9):1762-1771. doi: 10.1002/art.40151. Epub 2017 Aug 1.

8.

Enzyme reversal to explore the function of yeast E3 ubiquitin-ligases.

MacDonald C, Winistorfer S, Pope RM, Wright ME, Piper RC.

Traffic. 2017 Jul;18(7):465-484. doi: 10.1111/tra.12485. Epub 2017 Jun 1.

9.

SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages.

Shi B, Huang QQ, Birkett R, Doyle R, Dorfleutner A, Stehlik C, He C, Pope RM.

Autophagy. 2017 Feb;13(2):285-301. doi: 10.1080/15548627.2016.1261238. Epub 2016 Dec 8.

10.

The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases.

Cuda CM, Pope RM, Perlman H.

Nat Rev Rheumatol. 2016 Aug 23;12(9):543-58. doi: 10.1038/nrrheum.2016.132. Review.

11.

Deletion of calponin 2 in macrophages attenuates the severity of inflammatory arthritis in mice.

Huang QQ, Hossain MM, Sun W, Xing L, Pope RM, Jin JP.

Am J Physiol Cell Physiol. 2016 Oct 1;311(4):C673-C685. doi: 10.1152/ajpcell.00331.2015. Epub 2016 Aug 3.

12.

Association of Rheumatoid Factors With Subclinical and Clinical Atherosclerosis in African American Women: The Multiethnic Study of Atherosclerosis.

Majka DS, Vu TT, Pope RM, Teodorescu M, Karlson EW, Liu K, Chang RW.

Arthritis Care Res (Hoboken). 2017 Feb;69(2):166-174. doi: 10.1002/acr.22930.

13.

Tcf1 and Lef1 transcription factors establish CD8(+) T cell identity through intrinsic HDAC activity.

Xing S, Li F, Zeng Z, Zhao Y, Yu S, Shan Q, Li Y, Phillips FC, Maina PK, Qi HH, Liu C, Zhu J, Pope RM, Musselman CA, Zeng C, Peng W, Xue HH.

Nat Immunol. 2016 Jun;17(6):695-703. doi: 10.1038/ni.3456. Epub 2016 Apr 25.

14.

Cytochrome c adducts with PCB quinoid metabolites.

Li M, Teesch LM, Murry DJ, Pope RM, Li Y, Robertson LW, Ludewig G.

Environ Sci Pollut Res Int. 2016 Feb;23(3):2148-59. doi: 10.1007/s11356-015-4801-3. Epub 2015 Jun 12.

15.

CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis.

Huang QQ, Perlman H, Birkett R, Doyle R, Fang D, Haines GK, Robinson W, Datta S, Huang Z, Li QZ, Phee H, Pope RM.

Nat Commun. 2015 May 12;6:7086. doi: 10.1038/ncomms8086.

16.

Rapid identification and quantitative validation of a caffeine-degrading pathway in Pseudomonas sp. CES.

Yu CL, Summers RM, Li Y, Mohanty SK, Subramanian M, Pope RM.

J Proteome Res. 2015 Jan 2;14(1):95-106. doi: 10.1021/pr500751w. Epub 2014 Nov 24.

PMID:
25350919
17.

Fas signaling in macrophages promotes chronicity in K/BxN serum-induced arthritis.

Huang QQ, Birkett R, Koessler RE, Cuda CM, Haines GK 3rd, Jin JP, Perlman H, Pope RM.

Arthritis Rheumatol. 2014 Jan;66(1):68-77. doi: 10.1002/art.38198.

18.

Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets.

Sun X, Olivier AK, Liang B, Yi Y, Sui H, Evans TI, Zhang Y, Zhou W, Tyler SR, Fisher JT, Keiser NW, Liu X, Yan Z, Song Y, Goeken JA, Kinyon JM, Fligg D, Wang X, Xie W, Lynch TJ, Kaminsky PM, Stewart ZA, Pope RM, Frana T, Meyerholz DK, Parekh K, Engelhardt JF.

Am J Respir Cell Mol Biol. 2014 Mar;50(3):502-12. doi: 10.1165/rcmb.2013-0261OC.

19.

Antiphospholipid antibodies and sub-clinical atherosclerosis in the Coronary Artery Risk Development in Young Adults (CARDIA) cohort.

Majka DS, Liu K, Pope RM, Karlson EW, Vu TH, Teodorescu M, Chang RW.

Inflamm Res. 2013 Oct;62(10):919-27.

20.

CaMKII is essential for the proasthmatic effects of oxidation.

Sanders PN, Koval OM, Jaffer OA, Prasad AM, Businga TR, Scott JA, Hayden PJ, Luczak ED, Dickey DD, Allamargot C, Olivier AK, Meyerholz DK, Robison AJ, Winder DG, Blackwell TS, Dworski R, Sammut D, Wagner BA, Buettner GR, Pope RM, Miller FJ Jr, Dibbern ME, Haitchi HM, Mohler PJ, Howarth PH, Zabner J, Kline JN, Grumbach IM, Anderson ME.

Sci Transl Med. 2013 Jul 24;5(195):195ra97. doi: 10.1126/scitranslmed.3006135.

21.

Biochemical and biological characterization of exosomes containing prominin-1/CD133.

Rappa G, Mercapide J, Anzanello F, Pope RM, Lorico A.

Mol Cancer. 2013 Jun 14;12:62. doi: 10.1186/1476-4598-12-62.

22.

TLR2 deletion promotes arthritis through reduction of IL-10.

Huang QQ, Koessler RE, Birkett R, Perlman H, Xing L, Pope RM.

J Leukoc Biol. 2013 May;93(5):751-9. doi: 10.1189/jlb.0912473. Epub 2013 Feb 27.

23.

The role of glycoprotein 96 in the persistent inflammation of rheumatoid arthritis.

Huang QQ, Pope RM.

Arch Biochem Biophys. 2013 Feb 1;530(1):1-6. doi: 10.1016/j.abb.2012.12.008. Epub 2012 Dec 17. Review.

24.

ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting.

Humbert MC, Weihbrecht K, Searby CC, Li Y, Pope RM, Sheffield VC, Seo S.

Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19691-6. doi: 10.1073/pnas.1210916109. Epub 2012 Nov 12.

25.

Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma.

Bhattacharyya S, Kelley K, Melichian DS, Tamaki Z, Fang F, Su Y, Feng G, Pope RM, Budinger GR, Mutlu GM, Lafyatis R, Radstake T, Feghali-Bostwick C, Varga J.

Am J Pathol. 2013 Jan;182(1):192-205. doi: 10.1016/j.ajpath.2012.09.007. Epub 2012 Nov 7.

26.

Possible roles of IL-12-family cytokines in rheumatoid arthritis.

Pope RM, Shahrara S.

Nat Rev Rheumatol. 2013 Apr;9(4):252-6. doi: 10.1038/nrrheum.2012.170. Epub 2012 Oct 23. Review.

PMID:
23090510
27.

Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis.

Huang QQ, Koessler RE, Birkett R, Dorfleutner A, Perlman H, Haines GK 3rd, Stehlik C, Nicchitta CV, Pope RM.

Arthritis Rheum. 2012 Nov;64(11):3638-48. doi: 10.1002/art.34610.

28.

Ligation of TLR7 by rheumatoid arthritis synovial fluid single strand RNA induces transcription of TNFα in monocytes.

Chamberlain ND, Kim SJ, Vila OM, Volin MV, Volkov S, Pope RM, Arami S, Mandelin AM 2nd, Shahrara S.

Ann Rheum Dis. 2013 Mar;72(3):418-26. doi: 10.1136/annrheumdis-2011-201203. Epub 2012 Jun 23.

29.

TLR5, a novel and unidentified inflammatory mediator in rheumatoid arthritis that correlates with disease activity score and joint TNF-α levels.

Chamberlain ND, Vila OM, Volin MV, Volkov S, Pope RM, Swedler W, Mandelin AM 2nd, Shahrara S.

J Immunol. 2012 Jul 1;189(1):475-83. doi: 10.4049/jimmunol.1102977. Epub 2012 Jun 1.

30.

SNAPIN: an endogenous Toll-like receptor ligand in rheumatoid arthritis.

Shi B, Huang Q, Tak PP, Vervoordeldonk MJ, Huang CC, Dorfleutner A, Stehlik C, Pope RM.

Ann Rheum Dis. 2012 Aug;71(8):1411-7. doi: 10.1136/annrheumdis-2011-200899. Epub 2012 Apr 20.

PMID:
22523426
31.

Role of the CCL21 and CCR7 pathways in rheumatoid arthritis angiogenesis.

Pickens SR, Chamberlain ND, Volin MV, Pope RM, Talarico NE, Mandelin AM 2nd, Shahrara S.

Arthritis Rheum. 2012 Aug;64(8):2471-81. doi: 10.1002/art.34452.

32.

Portability of an algorithm to identify rheumatoid arthritis in electronic health records.

Carroll RJ, Thompson WK, Eyler AE, Mandelin AM, Cai T, Zink RM, Pacheco JA, Boomershine CS, Lasko TA, Xu H, Karlson EW, Perez RG, Gainer VS, Murphy SN, Ruderman EM, Pope RM, Plenge RM, Kho AN, Liao KP, Denny JC.

J Am Med Inform Assoc. 2012 Jun;19(e1):e162-9. Epub 2012 Feb 28.

33.

Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice.

Cuda CM, Agrawal H, Misharin AV, Haines GK 3rd, Hutcheson J, Weber E, Schoenfeldt JA, Mohan C, Pope RM, Perlman H.

Arthritis Rheum. 2012 Mar;64(3):808-20. doi: 10.1002/art.34317.

34.

More than just B-cell inhibition.

Ruderman EM, Pope RM.

Arthritis Res Ther. 2011 Aug 30;13(4):125. doi: 10.1186/ar3439.

35.

Anti-CXCL5 therapy ameliorates IL-17-induced arthritis by decreasing joint vascularization.

Pickens SR, Chamberlain ND, Volin MV, Gonzalez M, Pope RM, Mandelin AM 2nd, Kolls JK, Shahrara S.

Angiogenesis. 2011 Dec;14(4):443-55. doi: 10.1007/s10456-011-9227-z. Epub 2011 Jul 21.

36.

Activated TLR signaling in atherosclerosis among women with lower Framingham risk score: the multi-ethnic study of atherosclerosis.

Huang CC, Liu K, Pope RM, Du P, Lin S, Rajamannan NM, Huang QQ, Jafari N, Burke GL, Post W, Watson KE, Johnson C, Daviglus ML, Lloyd-Jones DM.

PLoS One. 2011;6(6):e21067. doi: 10.1371/journal.pone.0021067. Epub 2011 Jun 16.

37.

Characterization of interleukin-7 and interleukin-7 receptor in the pathogenesis of rheumatoid arthritis.

Pickens SR, Chamberlain ND, Volin MV, Pope RM, Talarico NE, Mandelin AM 2nd, Shahrara S.

Arthritis Rheum. 2011 Oct;63(10):2884-93. doi: 10.1002/art.30493.

38.

Characterization of CCL19 and CCL21 in rheumatoid arthritis.

Pickens SR, Chamberlain ND, Volin MV, Pope RM, Mandelin AM 2nd, Shahrara S.

Arthritis Rheum. 2011 Apr;63(4):914-22. doi: 10.1002/art.30232.

39.

FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasis.

Huang QQ, Perlman H, Huang Z, Birkett R, Kan L, Agrawal H, Misharin A, Gurbuxani S, Crispino JD, Pope RM.

Blood. 2010 Dec 2;116(23):4968-77. doi: 10.1182/blood-2009-11-252841. Epub 2010 Aug 19.

40.

Prostate secretions from men with chronic pelvic pain syndrome inhibit proinflammatory mediators.

Thumbikat P, Shahrara S, Sobkoviak R, Done J, Pope RM, Schaeffer AJ.

J Urol. 2010 Oct;184(4):1536-42. doi: 10.1016/j.juro.2010.05.086. Epub 2010 Aug 17.

41.

Innate immunity and rheumatoid arthritis.

Gierut A, Perlman H, Pope RM.

Rheum Dis Clin North Am. 2010 May;36(2):271-96. doi: 10.1016/j.rdc.2010.03.004. Review.

42.

Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis.

Huang Q, Pope RM.

J Leukoc Biol. 2010 Aug;88(2):253-62. doi: 10.1189/jlb.0310126. Epub 2010 May 19. Review. No abstract available.

43.

IL-17-mediated monocyte migration occurs partially through CC chemokine ligand 2/monocyte chemoattractant protein-1 induction.

Shahrara S, Pickens SR, Mandelin AM 2nd, Karpus WJ, Huang Q, Kolls JK, Pope RM.

J Immunol. 2010 Apr 15;184(8):4479-87. doi: 10.4049/jimmunol.0901942. Epub 2010 Mar 12.

44.

The synovial lining micromass system: toward rheumatoid arthritis in a dish?

Perlman H, Pope RM.

Arthritis Rheum. 2010 Mar;62(3):643-6. doi: 10.1002/art.27297. No abstract available.

45.

IL-17 contributes to angiogenesis in rheumatoid arthritis.

Pickens SR, Volin MV, Mandelin AM 2nd, Kolls JK, Pope RM, Shahrara S.

J Immunol. 2010 Mar 15;184(6):3233-41. doi: 10.4049/jimmunol.0903271. Epub 2010 Feb 19.

46.

Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis.

Scatizzi JC, Hutcheson J, Pope RM, Firestein GS, Koch AE, Mavers M, Smason A, Agrawal H, Haines GK 3rd, Chandel NS, Hotchkiss RS, Perlman H.

Arthritis Rheum. 2010 Feb;62(2):441-51. doi: 10.1002/art.27198.

47.

The role of toll-like receptors in rheumatoid arthritis.

Huang QQ, Pope RM.

Curr Rheumatol Rep. 2009 Oct;11(5):357-64. Review.

48.

Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling.

Huang QQ, Sobkoviak R, Jockheck-Clark AR, Shi B, Mandelin AM 2nd, Tak PP, Haines GK 3rd, Nicchitta CV, Pope RM.

J Immunol. 2009 Apr 15;182(8):4965-73. doi: 10.4049/jimmunol.0801563.

49.

Activation-induced degradation of FLIP(L) is mediated via the phosphatidylinositol 3-kinase/Akt signaling pathway in macrophages.

Shi B, Tran T, Sobkoviak R, Pope RM.

J Biol Chem. 2009 May 22;284(21):14513-23. doi: 10.1074/jbc.M807918200. Epub 2009 Apr 1.

50.

IL-17 induces monocyte migration in rheumatoid arthritis.

Shahrara S, Pickens SR, Dorfleutner A, Pope RM.

J Immunol. 2009 Mar 15;182(6):3884-91. doi: 10.4049/jimmunol.0802246.

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