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Items: 7


Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription.

Struntz NB, Chen A, Deutzmann A, Wilson RM, Stefan E, Evans HL, Ramirez MA, Liang T, Caballero F, Wildschut MHE, Neel DV, Freeman DB, Pop MS, McConkey M, Muller S, Curtin BH, Tseng H, Frombach KR, Butty VL, Levine SS, Feau C, Elmiligy S, Hong JA, Lewis TA, Vetere A, Clemons PA, Malstrom SE, Ebert BL, Lin CY, Felsher DW, Koehler AN.

Cell Chem Biol. 2019 May 16;26(5):711-723.e14. doi: 10.1016/j.chembiol.2019.02.009. Epub 2019 Mar 14.


Inhibition of Zinc-Dependent Histone Deacetylases with a Chemically Triggered Electrophile.

Boskovic ZV, Kemp MM, Freedy AM, Viswanathan VS, Pop MS, Fuller JH, Martinez NM, Figueroa LazĂș SO, Hong JA, Lewis TA, Calarese D, Love JD, Vetere A, Almo SC, Schreiber SL, Koehler AN.

ACS Chem Biol. 2016 Jul 15;11(7):1844-51. doi: 10.1021/acschembio.6b00012. Epub 2016 Apr 29.


Advances in discovering small molecules to probe protein function in a systems context.

Doyle SK, Pop MS, Evans HL, Koehler AN.

Curr Opin Chem Biol. 2016 Feb;30:28-36. doi: 10.1016/j.cbpa.2015.10.032. Epub 2015 Nov 23. Review.


Probing small-molecule microarrays with tagged proteins in cell lysates.

Pop MS, Wassaf D, Koehler AN.

Curr Protoc Chem Biol. 2014 Dec 1;6(4):209-20. doi: 10.1002/9780470559277.ch140101.


A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein.

Pop MS, Stransky N, Garvie CW, Theurillat JP, Hartman EC, Lewis TA, Zhong C, Culyba EK, Lin F, Daniels DS, Pagliarini R, Ronco L, Koehler AN, Garraway LA.

Mol Cancer Ther. 2014 Jun;13(6):1492-502. doi: 10.1158/1535-7163.MCT-13-0689. Epub 2014 Apr 15.


CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53.

Shi D, Pop MS, Kulikov R, Love IM, Kung AL, Grossman SR.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16275-80. doi: 10.1073/pnas.0904305106. Epub 2009 Sep 4. Erratum in: Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18427. Kung, Andrew [corrected to Kung, Andrew L].


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