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Items: 1 to 50 of 436

1.

IDH mutant lower grade (WHO Grades II/III) astrocytomas can be stratified for risk by CDKN2A, CDK4 and PDGFRA copy number alterations.

Yang RR, Shi ZF, Zhang ZY, Chan AK, Aibaidula A, Wang WW, Kwan JSH, Poon WS, Chen H, Li WC, Chung NY, Punchhi G, Chu WC, Chan IS, Liu XZ, Mao Y, Li KK, Ng HK.

Brain Pathol. 2019 Nov 16. doi: 10.1111/bpa.12801. [Epub ahead of print]

PMID:
31733156
2.

Identification of subsets of IDH-mutant glioblastomas with distinct epigenetic and copy number alterations and stratified clinical risks.

Li KK, Shi ZF, Malta TM, Chan AK, Cheng S, Kwan JSH, Yang RR, Poon WS, Mao Y, Noushmehr H, Chen H, Ng HK.

Neurooncol Adv. 2019 May-Dec;1(1):vdz015. doi: 10.1093/noajnl/vdz015. Epub 2019 Jul 17.

3.

Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.

Suzuki H, Kumar SA, Shuai S, Diaz-Navarro A, Gutierrez-Fernandez A, De Antonellis P, Cavalli FMG, Juraschka K, Farooq H, Shibahara I, Vladoiu MC, Zhang J, Abeysundara N, Przelicki D, Skowron P, Gauer N, Luu B, Daniels C, Wu X, Forget A, Momin A, Wang J, Dong W, Kim SK, Grajkowska WA, Jouvet A, Fèvre-Montange M, Garrè ML, Nageswara Rao AA, Giannini C, Kros JM, French PJ, Jabado N, Ng HK, Poon WS, Eberhart CG, Pollack IF, Olson JM, Weiss WA, Kumabe T, López-Aguilar E, Lach B, Massimino M, Van Meir EG, Rubin JB, Vibhakar R, Chambless LB, Kijima N, Klekner A, Bognár L, Chan JA, Faria CC, Ragoussis J, Pfister SM, Goldenberg A, Wechsler-Reya RJ, Bailey SD, Garzia L, Morrissy AS, Marra MA, Huang X, Malkin D, Ayrault O, Ramaswamy V, Puente XS, Calarco JA, Stein L, Taylor MD.

Nature. 2019 Oct;574(7780):707-711. doi: 10.1038/s41586-019-1650-0. Epub 2019 Oct 9.

PMID:
31664194
4.

The Dynamics of Microglial Polarization Reveal the Resident Neuroinflammatory Responses After Subarachnoid Hemorrhage.

Zheng ZV, Lyu H, Lam SYE, Lam PK, Poon WS, Wong GKC.

Transl Stroke Res. 2019 Oct 18. doi: 10.1007/s12975-019-00728-5. [Epub ahead of print]

PMID:
31628642
5.

Recurrent non-coding U1-snRNA mutations drive cryptic splicing in Shh medulloblastoma.

Suzuki H, Kumar SA, Shuai S, Diaz-Navarro A, Gutierrez-Fernandez A, De Antonellis P, Cavalli FMG, Juraschka K, Farooq H, Shibahara I, Vladoiu MC, Zhang J, Abeysundara N, Przelicki D, Skowron P, Gauer N, Luu B, Daniels C, Wu X, Forget A, Momin A, Wang J, Dong W, Kim SK, Grajkowska WA, Jouvet A, Fèvre-Montange M, Garrè ML, Rao AAN, Giannini C, Kros JM, French PJ, Jabado N, Ng HK, Poon WS, Eberhart CG, Pollack IF, Olson JM, Weiss WA, Kumabe T, López-Aguilar E, Lach B, Massimino M, Van Meir EG, Rubin JB, Vibhakar R, Chambless LB, Kijima N, Klekner A, Bognár L, Chan JA, Faria CC, Ragoussis J, Pfister SM, Goldenberg A, Wechsler-Reya RJ, Bailey SD, Garzia L, Morrissy AS, Marra MA, Huang X, Malkin D, Ayrault O, Ramaswamy V, Puente XS, Calarco JA, Stein L, Taylor MD.

Nature. 2019 Oct 9. doi: 10.1038/s41586-019-1650-0. [Epub ahead of print]

PMID:
31597162
6.

Study of the association between gait variability and gene expressions in a mouse model of transient focal ischemic stroke.

Chen M, Lyu H, Li T, Su XW, Leung CK, Xiong MZQ, Poon WS, Cai YF, Lu G, Chan WY, Wang LX.

Int J Neurosci. 2019 Oct 13:1-12. doi: 10.1080/00207454.2019.1663188. [Epub ahead of print]

PMID:
31512542
7.

Topically applied adipose-derived mesenchymal stem cell treatment in experimental focal cerebral ischemia.

Lam PK, Wang KKW, Chin DWC, Tong CSW, Wang Y, Lo KKY, Lai PBS, Ma H, Zheng VZY, Poon WS, Wong GKC.

J Clin Neurosci. 2019 Aug 17. pii: S0967-5868(19)31149-X. doi: 10.1016/j.jocn.2019.08.051. [Epub ahead of print]

PMID:
31431402
8.

Topically applied adipose-derived mesenchymal stem cell treatment in experimental focal cerebral ischaemia.

Wong GKC, Lam PK, Lo AWI, Chan AKY, Wang YX, Poon WS.

Hong Kong Med J. 2019 Aug;25 Suppl 5(4):17. No abstract available.

9.

Development of a Delayed Cerebral Infarction Load Scoring System (DCI Score).

Wong GKC, Nung RCH, Sitt JCM, Mok VCT, Wong A, Poon WS, Wang D, Abrigo J, Siu DYW.

Acta Neurochir Suppl. 2020;127:145-148. doi: 10.1007/978-3-030-04615-6_21.

PMID:
31407075
10.

The Time Course of Cognitive Deficits in Experimental Subarachnoid Hemorrhage.

Zheng ZV, Lam PK, Poon WS, Wong KCG.

Acta Neurochir Suppl. 2020;127:121-125. doi: 10.1007/978-3-030-04615-6_18.

PMID:
31407072
11.

Mortality And Morbidity of Severe Traumatic Brain Injuries; A Pediatric Intensive Care Unit Experience Over 15 Years.

Hon KL, Huang S, Poon WS, Cheung HM, Ip P, Zee B.

Bull Emerg Trauma. 2019 Jul;7(3):256-262. doi: 10.29252/beat-070308.

12.

The importance of aspirin, catheterization accuracy, and catheter design in external ventricular drainage-related hemorrhage: a multicenter study of 1002 procedures.

Woo PYM, Ng BCF, Xiao JX, Wong D, Seto A, Lam S, Yim C, Lo HY, Po YC, Wong LYW, Lee MWY, Yam KY, Pu JKS, Chan KY, Poon WS.

Acta Neurochir (Wien). 2019 Aug;161(8):1623-1632. doi: 10.1007/s00701-019-03978-2. Epub 2019 Jun 20.

PMID:
31222516
13.

The neuroprotection of hypoxic adipose tissue-derived mesenchymal stem cells in experimental traumatic brain injury.

Ma H, Lam PK, Tong CSW, Lo KKY, Wong GKC, Poon WS.

Cell Transplant. 2019 Jul;28(7):874-884. doi: 10.1177/0963689719855624. Epub 2019 Jun 12.

14.

Long-term outcomes of ruptured cerebral arteriovenous malformations in the paediatric population: A retrospective review in a regional hospital in Hong Kong.

Tam KY, Lim K, Zhu CXL, Chan KY, Poon WS, Poon D, Kam M, Cheung M, Wong KCG.

J Clin Neurosci. 2019 Aug;66:66-70. doi: 10.1016/j.jocn.2019.05.022. Epub 2019 May 31.

PMID:
31160200
15.

Baicalein enhances the effect of low dose Levodopa on the gait deficits and protects dopaminergic neurons in experimental Parkinsonism.

Zheng ZV, Cheung CY, Lyu H, Chan HY, Li Y, Bian ZX, Wang KKW, Poon WS.

J Clin Neurosci. 2019 Jun;64:242-251. doi: 10.1016/j.jocn.2019.02.005. Epub 2019 Mar 21.

PMID:
30905662
16.

Determining a cut-off residual tumor volume threshold for patients with newly diagnosed glioblastoma treated with temozolomide chemoradiotherapy: A multicenter cohort study.

Woo PYM, Ho JMK, Tse TPK, Lam SW, Mak CHK, Chan DTM, Lee MWY, Wong ST, Chan KY, Poon WS.

J Clin Neurosci. 2019 May;63:134-141. doi: 10.1016/j.jocn.2019.01.022. Epub 2019 Jan 31.

PMID:
30712777
17.

Characterization of Axon Damage, Neurological Deficits, and Histopathology in Two Experimental Models of Intracerebral Hemorrhage.

Liu Y, Lu G, Su XW, Ding T, Wang WL, Li YM, Poon WS, Ao LJ.

Front Neurosci. 2018 Dec 11;12:928. doi: 10.3389/fnins.2018.00928. eCollection 2018.

18.

Plasma and CSF miRNA dysregulations in subarachnoid hemorrhage reveal clinical courses and underlying pathways.

Chan MTH, Wong JYY, Leung AKT, Lu G, Poon WS, Lau AY, Chan WY, Wong GKC.

J Clin Neurosci. 2019 Apr;62:155-161. doi: 10.1016/j.jocn.2018.11.038. Epub 2018 Nov 24.

PMID:
30482403
19.

Blessing or burden? Long-term maintenance, complications and clinical outcome of intrathecal baclofen pumps.

Chan DY, Chan SS, Chan EK, Ng AY, Ying AC, Li AC, Chiu CC, Cheung N, Mak WK, Sun DT, Zhu CX, Poon WS.

Surg Pract. 2018 Aug;22(3):105-110. doi: 10.1111/1744-1633.12308. Epub 2018 Jul 4.

20.

Forward and reverse mutations in stages of cancer development.

Hu T, Kumar Y, Shazia I, Duan SJ, Li Y, Chen L, Chen JF, Yin R, Kwong A, Leung GK, Mat WK, Wu Z, Long X, Chan CH, Chen S, Lee P, Ng SK, Ho TYC, Yang J, Ding X, Tsang SY, Zhou X, Zhang DH; International Cancer Genome Consortium, Zhou EX, Xu L, Poon WS, Wang HY, Xue H.

Hum Genomics. 2018 Aug 22;12(1):40. doi: 10.1186/s40246-018-0170-6.

21.

Safety and Efficacy of Atorvastatin for Chronic Subdural Hematoma in Chinese Patients: A Randomized ClinicalTrial.

Jiang R, Zhao S, Wang R, Feng H, Zhang J, Li X, Mao Y, Yuan X, Fei Z, Zhao Y, Yu X, Poon WS, Zhu X, Liu N, Kang D, Sun T, Jiao B, Liu X, Yu R, Zhang J, Gao G, Hao J, Su N, Yin G, Zhu X, Lu Y, Wei J, Hu J, Hu R, Li J, Wang D, Wei H, Tian Y, Lei P, Dong JF, Zhang J.

JAMA Neurol. 2018 Nov 1;75(11):1338-1346. doi: 10.1001/jamaneurol.2018.2030.

22.

Pediatric low-grade gliomas can be molecularly stratified for risk.

Yang RR, Aibaidula A, Wang WW, Chan AK, Shi ZF, Zhang ZY, Chan DTM, Poon WS, Liu XZ, Li WC, Zhang RQ, Li YX, Chung NY, Chen H, Wu J, Zhou L, Li KK, Ng HK.

Acta Neuropathol. 2018 Oct;136(4):641-655. doi: 10.1007/s00401-018-1874-3. Epub 2018 Jun 14.

PMID:
29948154
23.

Assessment of long-term functional outcome in patients who sustained moderate or major trauma: a 4-year prospective cohort study.

Rainer TH, Graham CA, Yeung HH, Poon WS, Ho HF, Kam CW, Cameron P.

Hong Kong Med J. 2018 Feb;24 Suppl 2(1):30-33. No abstract available.

24.

Ictal intracranial electroencephalography using wavelet analysis of high-frequency oscillations in Chinese patients with refractory epilepsy.

Leung HW, Poon WS, Kwan PK, Lui CH, Poon TL, Chan EL, Yuen SC.

Hong Kong Med J. 2018 Jun;24 Suppl 3(3):21-23. No abstract available.

25.

Oligodendrogliomas in pediatric and teenage patients only rarely exhibit molecular markers and patients have excellent survivals.

Li YX, Aibaidula A, Shi Z, Chen H, Li KK, Chung NY, Yang RR, Chan DT, Poon WS, Lee KLR, Mao Y, Wu J, Chan AK, Zhou L, Ng HK.

J Neurooncol. 2018 Sep;139(2):307-322. doi: 10.1007/s11060-018-2890-9. Epub 2018 May 14.

PMID:
29761369
26.

Techniques for Stereotactic Neurosurgery: Beyond the Frame, Toward the Intraoperative Magnetic Resonance Imaging-Guided and Robot-Assisted Approaches.

Guo Z, Leong MC, Su H, Kwok KW, Chan DT, Poon WS.

World Neurosurg. 2018 Aug;116:77-87. doi: 10.1016/j.wneu.2018.04.155. Epub 2018 May 3. Review.

PMID:
29730102
27.

A Comparative Analysis of the Usefulness of Survival Prediction Models for Patients with Glioblastoma in the Temozolomide Era: The Importance of Methylguanine Methyltransferase Promoter Methylation, Extent of Resection, and Subventricular Zone Location.

Woo P, Ho J, Lam S, Ma E, Chan D, Wong WK, Mak C, Lee M, Wong ST, Chan KY, Poon WS.

World Neurosurg. 2018 Jul;115:e375-e385. doi: 10.1016/j.wneu.2018.04.059. Epub 2018 Apr 17.

PMID:
29678708
28.

Awake craniotomy for excision of arteriovenous malformations? A qualitative comparison study with stereotactic radiosurgery.

Chan DYC, Chan DTM, Zhu CXL, Kan PKY, Ng AY, Hsieh YS, Abrigo J, Poon WS, Wong GKC.

J Clin Neurosci. 2018 May;51:52-56. doi: 10.1016/j.jocn.2018.02.019. Epub 2018 Mar 9.

PMID:
29530384
29.

Cognitive Outcomes of Patients with Traumatic Bifrontal Contusions.

Wong GKC, Ngai K, Poon WS, Zheng VZY, Yu C.

Acta Neurochir Suppl. 2018;126:63-65. doi: 10.1007/978-3-319-65798-1_14.

PMID:
29492534
30.

Neuroprotective effect of Da Chuanxiong Formula against cognitive and motor deficits in a rat controlled cortical impact model of traumatic brain injury.

Liu ZK, Ng CF, Shiu HT, Wong HL, Chin WC, Zhang JF, Lam PK, Poon WS, Lau CB, Leung PC, Ko CH.

J Ethnopharmacol. 2018 May 10;217:11-22. doi: 10.1016/j.jep.2018.02.004. Epub 2018 Feb 6.

PMID:
29425850
31.

Elderly population have a decreased aneurysmal subarachnoid hemorrhage incidence rate than Middle aged population: a descriptive analysis of 8,144 cases in mainland China.

Wáng YXJ, Zhang L, Zhao L, He J, Zeng XJ, Liu H, Yang YJ, Ding SW, Xu ZF, He YM, Yang L, Sun L, Mu KJ, Wang BS, Xu XH, Ji ZY, Liu JH, Fang JZ, Hou R, Fan F, Peng GM, Zhu YQ, Ju SH, Poon WS.

Br J Neurosurg. 2018 Apr;32(2):165-171. doi: 10.1080/02688697.2018.1426724. Epub 2018 Jan 17.

PMID:
29338437
32.

"Triggers" for referral to neurology palliative care service.

Chang RS, Poon WS.

Ann Palliat Med. 2018 Jul;7(3):289-295. doi: 10.21037/apm.2017.08.02. Epub 2017 Aug 31. Review.

33.

Early versus Late Application of Subthalamic deep brain Stimulation to Parkinson's disease patients with motor complications (ELASS): protocol of a multicentre, prospective and observational study.

Jiang L, Poon WS, Moro E, Xian W, Yang C, Zhu XL, Gu J, Cai X, Liu J, Mok V, Liu Y, Xu S, Guo Q, Chen W, Chen L.

BMJ Open. 2017 Nov 16;7(11):e018610. doi: 10.1136/bmjopen-2017-018610.

34.

Plasma miR-124 Is a Promising Candidate Biomarker for Human Intracerebral Hemorrhage Stroke.

Wang Z, Lu G, Sze J, Liu Y, Lin S, Yao H, Zhang J, Xie D, Liu Q, Kung HF, Lin MC, Poon WS.

Mol Neurobiol. 2018 Jul;55(7):5879-5888. doi: 10.1007/s12035-017-0808-8. Epub 2017 Nov 3.

35.

Phase I/II randomized controlled trial of autologous bone marrow-derived mesenchymal stem cell therapy for chronic stroke.

Tsang KS, Ng CPS, Zhu XL, Wong GKC, Lu G, Ahuja AT, Wong KSL, Ng HK, Poon WS.

World J Stem Cells. 2017 Aug 26;9(8):133-143. doi: 10.4252/wjsc.v9.i8.133.

36.

Minimum Clinically Important Difference of Montreal Cognitive Assessment in aneurysmal subarachnoid hemorrhage patients.

Wong GKC, Mak JSY, Wong A, Zheng VZY, Poon WS, Abrigo J, Mok VCT.

J Clin Neurosci. 2017 Dec;46:41-44. doi: 10.1016/j.jocn.2017.08.039. Epub 2017 Sep 5.

PMID:
28887072
37.

5-Aminolevulinic acid fluorescence guided resection of malignant glioma: Hong Kong experience.

Chan DTM, Yi-Pin Sonia H, Poon WS.

Asian J Surg. 2018 Sep;41(5):467-472. doi: 10.1016/j.asjsur.2017.06.004. Epub 2017 Aug 26.

38.

Feasibility and safety of extended adjuvant temozolomide beyond six cycles for patients with glioblastoma.

Hsieh SY, Chan DT, Kam MK, Loong HH, Tsang WK, Poon DM, Ng SC, Poon WS.

Hong Kong Med J. 2017 Dec;23(6):594-8. doi: 10.12809/hkmj165002. Epub 2017 Aug 11.

39.

miR-181d regulates human dendritic cell maturation through NF-κB pathway.

Su XW, Lu G, Leung CK, Liu Q, Li Y, Tsang KS, Zhao SD, Chan DTM, Kung HF, Poon WS.

Cell Prolif. 2017 Oct;50(5). doi: 10.1111/cpr.12358. Epub 2017 Jul 21.

PMID:
28731516
40.

Moving the goalposts: A comparison of different definitions for primary external ventricular drain infection and its risk factors: A multi-center study of 2575 patients.

Woo PYM, Wong HT, Pu JKS, Wong WK, Wong LYW, Lee MWY, Yam KY, Lui WM, Poon WS.

J Clin Neurosci. 2017 Nov;45:67-72. doi: 10.1016/j.jocn.2017.05.042. Epub 2017 Jul 14.

PMID:
28716567
41.

Interactome and reciprocal activation of pathways in topical mesenchymal stem cells and the recipient cerebral cortex following traumatic brain injury.

Lam PK, Wang KKW, Lo AWI, Tong CSW, Ching DWC, Wong K, Yang Z, Kong T, Lo KKY, Choy RKW, Lai PBS, Wong GKC, Poon WS.

Sci Rep. 2017 Jul 10;7(1):5017. doi: 10.1038/s41598-017-01772-7.

42.

MicroRNA-182 Regulates Neurite Outgrowth Involving the PTEN/AKT Pathway.

Wang WM, Lu G, Su XW, Lyu H, Poon WS.

Front Cell Neurosci. 2017 Apr 10;11:96. doi: 10.3389/fncel.2017.00096. eCollection 2017.

43.

Circulating MicroRNAs in Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage.

Lu G, Wong MS, Xiong MZQ, Leung CK, Su XW, Zhou JY, Poon WS, Zheng VZY, Chan WY, Wong GKC.

J Am Heart Assoc. 2017 Apr 25;6(4). pii: e005363. doi: 10.1161/JAHA.116.005363.

44.

Cryostored autologous skull bone for cranioplasty? A study on cranial bone flaps' viability and microbial contamination after deep-frozen storage at -80°C.

Chan DYC, Mok YT, Lam PK, Tong CSW, Ng SCP, Sun TFD, Poon WS.

J Clin Neurosci. 2017 Aug;42:81-83. doi: 10.1016/j.jocn.2017.04.016. Epub 2017 Apr 18.

45.

Enhanced expression of Vastatin inhibits angiogenesis and prolongs survival in murine orthotopic glioblastoma model.

Li Y, Li J, Woo YM, Shen Z, Yao H, Cai Y, Lin MC, Poon WS.

BMC Cancer. 2017 Feb 13;17(1):126. doi: 10.1186/s12885-017-3125-8.

46.

Inhibition of NF-κB Pathway and Modulation of MAPK Signaling Pathways in Glioblastoma and Implications for Lovastatin and Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) Combination Therapy.

Liu PC, Lu G, Deng Y, Wang CD, Su XW, Zhou JY, Chan TM, Hu X, Poon WS.

PLoS One. 2017 Jan 30;12(1):e0171157. doi: 10.1371/journal.pone.0171157. eCollection 2017.

47.

A traditional Chinese formula composed of Chuanxiong Rhizoma and Gastrodiae Rhizoma (Da Chuanxiong Formula) suppresses inflammatory response in LPS -induced RAW 264.7 cells through inhibition of NF-κB pathway.

Liu ZK, Ng CF, Shiu HT, Wong HL, Wong CW, Li KK, Zhang JF, Lam PK, Poon WS, Lau CB, Leung PC, Ko CH.

J Ethnopharmacol. 2017 Jan 20;196:20-28. doi: 10.1016/j.jep.2016.12.014. Epub 2016 Dec 11.

PMID:
27965052
48.

Use of subdural drain for chronic subdural haematoma? A 4-year multi-centre observational study of 302 cases.

Chan DY, Woo PY, Mak CH, Chu AC, Li CC, Ko NM, Ng SC, Sun TF, Poon WS.

J Clin Neurosci. 2017 Feb;36:27-30. doi: 10.1016/j.jocn.2016.10.039. Epub 2016 Nov 30.

PMID:
27914805
49.

Ten-year review of survival and management of malignant glioma in Hong Kong.

Chan DT, Hsieh SY, Lau CK, Kam MK, Loong HH, Tsang WK, Poon DM, Poon WS.

Hong Kong Med J. 2017 Apr;23(2):134-9. doi: 10.12809/hkmj164879. Epub 2016 Dec 2.

50.

The use of atorvastatin for chronic subdural haematoma: a retrospective cohort comparison study.

Chan DY, Chan DT, Sun TF, Ng SC, Wong GK, Poon WS.

Br J Neurosurg. 2017 Feb;31(1):72-77. doi: 10.1080/02688697.2016.1208806. Epub 2016 Nov 23.

PMID:
27881024

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