Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 190

1.

Risk assessment of the tropism & pathogenesis of the highly pathogenic avian influenza A/H7N9 virus using ex vivo & in vitro cultures of human respiratory tract.

Chan LLY, Hui KPY, Kuok DIT, Bui CHT, Ng KC, Mok CKP, Yang ZF, Guan W, Poon LLM, Zhong N, Peiris JSM, Nicholls JM, Chan MCW.

J Infect Dis. 2019 Apr 18. pii: jiz165. doi: 10.1093/infdis/jiz165. [Epub ahead of print]

PMID:
31001638
2.

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.

Laursen NS, Friesen RHE, Zhu X, Jongeneelen M, Blokland S, Vermond J, van Eijgen A, Tang C, van Diepen H, Obmolova G, van der Neut Kolfschoten M, Zuijdgeest D, Straetemans R, Hoffman RMB, Nieusma T, Pallesen J, Turner HL, Bernard SM, Ward AB, Luo J, Poon LLM, Tretiakova AP, Wilson JM, Limberis MP, Vogels R, Brandenburg B, Kolkman JA, Wilson IA.

Science. 2018 Nov 2;362(6414):598-602. doi: 10.1126/science.aaq0620.

3.

Combined use of live-attenuated and inactivated influenza vaccines to enhance heterosubtypic protection.

Yan LM, Li OTW, Poh CM, Perera RAPM, Valkenburg SA, Peiris M, Poon LLM.

Virology. 2018 Dec;525:73-82. doi: 10.1016/j.virol.2018.09.007. Epub 2018 Sep 21.

PMID:
30248524
4.

Mini viral RNAs act as innate immune agonists during influenza virus infection.

Te Velthuis AJW, Long JC, Bauer DLV, Fan RLY, Yen HL, Sharps J, Siegers JY, Killip MJ, French H, Oliva-Martín MJ, Randall RE, de Wit E, van Riel D, Poon LLM, Fodor E.

Nat Microbiol. 2018 Nov;3(11):1234-1242. doi: 10.1038/s41564-018-0240-5. Epub 2018 Sep 17.

5.

Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016.

So RT, Perera RA, Oladipo JO, Chu DK, Kuranga SA, Chan KH, Lau EH, Cheng SM, Poon LL, Webby RJ, Peiris M.

Euro Surveill. 2018 Aug;23(32). doi: 10.2807/1560-7917.ES.2018.23.32.1800175.

6.

The Hurdles From Bench to Bedside in the Realization and Implementation of a Universal Influenza Vaccine.

Valkenburg SA, Leung NHL, Bull MB, Yan LM, Li APY, Poon LLM, Cowling BJ.

Front Immunol. 2018 Jul 2;9:1479. doi: 10.3389/fimmu.2018.01479. eCollection 2018. Review.

7.

Circulation of Influenza A(H5N8) Virus, Saudi Arabia.

Al-Ghadeer H, Chu DKW, Rihan EMA, Abd-Allah EA, Gu H, Chin AWH, Qasim IA, Aldoweriej A, Alharbi SS, Al-Aqil MA, Al-Sahaf A, Abdel Rahman SS, Aljassem AH, Abdul-Al A, Aljasir MR, Alhammad YMO, Kasem S, Peiris M, Zaki AZSA, Poon LLM.

Emerg Infect Dis. 2018 Oct;24(10):1961-1964. doi: 10.3201/eid2410.180846. Epub 2018 Oct 17.

8.

Protection by universal influenza vaccine is mediated by memory CD4 T cells.

Valkenburg SA, Li OTW, Li A, Bull M, Waldmann TA, Perera LP, Peiris M, Poon LLM.

Vaccine. 2018 Jul 5;36(29):4198-4206. doi: 10.1016/j.vaccine.2018.06.007. Epub 2018 Jun 7.

PMID:
29887326
9.

Replicative virus shedding in the respiratory tract of patients with Middle East respiratory syndrome coronavirus infection.

Park WB, Poon LLM, Choi SJ, Choe PG, Song KH, Bang JH, Kim ES, Kim HB, Park SW, Kim NJ, Peiris M, Oh MD.

Int J Infect Dis. 2018 Jul;72:8-10. doi: 10.1016/j.ijid.2018.05.003. Epub 2018 May 9.

10.

MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity.

Chu DKW, Hui KPY, Perera RAPM, Miguel E, Niemeyer D, Zhao J, Channappanavar R, Dudas G, Oladipo JO, Traoré A, Fassi-Fihri O, Ali A, Demissié GF, Muth D, Chan MCW, Nicholls JM, Meyerholz DK, Kuranga SA, Mamo G, Zhou Z, So RTY, Hemida MG, Webby RJ, Roger F, Rambaut A, Poon LLM, Perlman S, Drosten C, Chevalier V, Peiris M.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3144-3149. doi: 10.1073/pnas.1718769115. Epub 2018 Mar 5.

11.

Identification of influenza polymerase inhibitors targeting C-terminal domain of PA through surface plasmon resonance screening.

Lo CY, Li OT, Tang WP, Hu C, Wang GX, Ngo JC, Wan DC, Poon LL, Shaw PC.

Sci Rep. 2018 Feb 2;8(1):2280. doi: 10.1038/s41598-018-20772-9.

12.

Immune Responses to Twice-Annual Influenza Vaccination in Older Adults in Hong Kong.

Tam YH, Valkenburg SA, Perera RAPM, Wong JHF, Fang VJ, Ng TWY, Kwong ASK, Tsui WWS, Ip DKM, Poon LLM, Chau CKV, Barr IG, Peiris JSM, Cowling BJ.

Clin Infect Dis. 2018 Mar 5;66(6):904-912. doi: 10.1093/cid/cix900.

PMID:
29069368
13.

Cross-sectional study of MERS-CoV-specific RNA and antibodies in animals that have had contact with MERS patients in Saudi Arabia.

Kasem S, Qasim I, Al-Hufofi A, Hashim O, Alkarar A, Abu-Obeida A, Gaafer A, Elfadil A, Zaki A, Al-Romaihi A, Babekr N, El-Harby N, Hussien R, Al-Sahaf A, Al-Doweriej A, Bayoumi F, Poon LLM, Chu DKW, Peiris M, Perera RAPM.

J Infect Public Health. 2018 May - Jun;11(3):331-338. doi: 10.1016/j.jiph.2017.09.022. Epub 2017 Oct 6.

14.

Characterization of influenza A viruses with polymorphism in PB2 residues 701 and 702.

Chin AWH, Leong NKC, Nicholls JM, Poon LLM.

Sci Rep. 2017 Sep 12;7(1):11361. doi: 10.1038/s41598-017-11625-y.

15.

A46 MERS-CoV in Arabian camels in Africa and Central Asia.

Chu DKW, Chan SMS, Perera RAPM, Miguel E, Roger F, Chevalier V, Poon LLM, Peiris M.

Virus Evol. 2017 Mar 5;3(Suppl 1). pii: vew036.045. doi: 10.1093/ve/vew036.045. eCollection 2017 Mar. No abstract available.

16.

Longitudinal study of Middle East Respiratory Syndrome coronavirus infection in dromedary camel herds in Saudi Arabia, 2014-2015.

Hemida MG, Alnaeem A, Chu DK, Perera RA, Chan SM, Almathen F, Yau E, Ng BC, Webby RJ, Poon LL, Peiris M.

Emerg Microbes Infect. 2017 Jun 21;6(6):e56. doi: 10.1038/emi.2017.44.

17.

Identification of influenza polymerase inhibitors targeting polymerase PB2 cap-binding domain through virtual screening.

Liu M, Lo CY, Wang G, Chow HF, Ngo JC, Wan DC, Poon LL, Shaw PC.

Antiviral Res. 2017 Aug;144:186-195. doi: 10.1016/j.antiviral.2017.06.009. Epub 2017 Jun 16.

PMID:
28629986
18.

MERS-CoV Antibody Responses 1 Year after Symptom Onset, South Korea, 2015.

Choe PG, Perera RAPM, Park WB, Song KH, Bang JH, Kim ES, Kim HB, Ko LWR, Park SW, Kim NJ, Lau EHY, Poon LLM, Peiris M, Oh MD.

Emerg Infect Dis. 2017 Jul;23(7):1079-1084. doi: 10.3201/eid2307.170310. Epub 2017 Jul 15.

19.

Coronavirus infections in horses in Saudi Arabia and Oman.

Hemida MG, Chu DKW, Perera RAPM, Ko RLW, So RTY, Ng BCY, Chan SMS, Chu S, Alnaeem AA, Alhammadi MA, Webby RJ, Poon LLM, Balasuriya UBR, Peiris M.

Transbound Emerg Dis. 2017 Dec;64(6):2093-2103. doi: 10.1111/tbed.12630. Epub 2017 Mar 13.

PMID:
28296228
20.

Preexisting Antibody-Dependent Cellular Cytotoxicity-Activating Antibody Responses Are Stable Longitudinally and Cross-reactive Responses Are Not Boosted by Recent Influenza Exposure.

Valkenburg SA, Zhang Y, Chan KY, Leung K, Wu JT, Poon LL.

J Infect Dis. 2016 Oct 15;214(8):1159-63. doi: 10.1093/infdis/jiw346. Epub 2016 Aug 4.

21.

Age-specific genetic and antigenic variations of influenza A viruses in Hong Kong, 2013-2014.

Cao P, Wong CM, Chan KH, Wang X, Chan KP, Peiris JS, Poon LL, Yang L.

Sci Rep. 2016 Jul 25;6:30260. doi: 10.1038/srep30260.

22.
23.

Stalking influenza by vaccination with pre-fusion headless HA mini-stem.

Valkenburg SA, Mallajosyula VV, Li OT, Chin AW, Carnell G, Temperton N, Varadarajan R, Poon LL.

Sci Rep. 2016 Mar 7;6:22666. doi: 10.1038/srep22666.

24.

Quantifying influenza virus diversity and transmission in humans.

Poon LL, Song T, Rosenfeld R, Lin X, Rogers MB, Zhou B, Sebra R, Halpin RA, Guan Y, Twaddle A, DePasse JV, Stockwell TB, Wentworth DE, Holmes EC, Greenbaum B, Peiris JS, Cowling BJ, Ghedin E.

Nat Genet. 2016 Feb;48(2):195-200. doi: 10.1038/ng.3479. Epub 2016 Jan 4.

25.

Recombinant influenza virus with a pandemic H2N2 polymerase complex has a higher adaptive potential than one with seasonal H2N2 polymerase complex.

Chin AW, Yen HL, Krauss S, Webby RJ, Poon LL.

J Gen Virol. 2016 Mar;97(3):611-9. doi: 10.1099/jgv.0.000385. Epub 2015 Dec 24.

26.

Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels in Nigeria, 2015.

Chu DK, Oladipo JO, Perera RA, Kuranga SA, Chan SM, Poon LL, Peiris M.

Euro Surveill. 2015;20(49). doi: 10.2807/1560-7917.ES.2015.20.49.30086.

27.

Asymptomatic MERS-CoV Infection in Humans Possibly Linked to Infected Dromedaries Imported from Oman to United Arab Emirates, May 2015.

Al Hammadi ZM, Chu DK, Eltahir YM, Al Hosani F, Al Mulla M, Tarnini W, Hall AJ, Perera RA, Abdelkhalek MM, Peiris JS, Al Muhairi SS, Poon LL.

Emerg Infect Dis. 2015 Dec;21(12):2197-200. doi: 10.3201/eid2112.151132.

28.

Comparison of serological assays in human Middle East respiratory syndrome (MERS)-coronavirus infection.

Park SW, Perera RA, Choe PG, Lau EH, Choi SJ, Chun JY, Oh HS, Song KH, Bang JH, Kim ES, Kim HB, Park WB, Kim NJ, Poon LL, Peiris M, Oh MD.

Euro Surveill. 2015;20(41). doi: 10.2807/1560-7917.ES.2015.20.41.30042.

29.

Evidence for an Ancestral Association of Human Coronavirus 229E with Bats.

Corman VM, Baldwin HJ, Tateno AF, Zerbinati RM, Annan A, Owusu M, Nkrumah EE, Maganga GD, Oppong S, Adu-Sarkodie Y, Vallo P, da Silva Filho LV, Leroy EM, Thiel V, van der Hoek L, Poon LL, Tschapka M, Drosten C, Drexler JF.

J Virol. 2015 Dec;89(23):11858-70. doi: 10.1128/JVI.01755-15. Epub 2015 Sep 16.

30.

Generation of Live Attenuated Influenza Virus by Using Codon Usage Bias.

Fan RL, Valkenburg SA, Wong CK, Li OT, Nicholls JM, Rabadan R, Peiris JS, Poon LL.

J Virol. 2015 Nov;89(21):10762-73. doi: 10.1128/JVI.01443-15. Epub 2015 Aug 12.

31.

Transmission of H7N9 Influenza Viruses with a Polymorphism at PB2 Residue 627 in Chickens and Ferrets.

Luk GS, Leung CY, Sia SF, Choy KT, Zhou J, Ho CC, Cheung PP, Lee EF, Wai CK, Li PC, Ip SM, Poon LL, Lindsley WG, Peiris M, Yen HL.

J Virol. 2015 Oct;89(19):9939-51. doi: 10.1128/JVI.01444-15. Epub 2015 Jul 22.

32.

Absence of MERS-Coronavirus in Bactrian Camels, Southern Mongolia, November 2014.

Chan SM, Damdinjav B, Perera RA, Chu DK, Khishgee B, Enkhbold B, Poon LL, Peiris M.

Emerg Infect Dis. 2015 Jul;21(7):1269-71. doi: 10.3201/eid2107.150178. No abstract available.

33.

Pseudoparticle neutralization assay for detecting ebola- neutralizing antibodies in biosafety level 2 settings.

Chin AW, Perera RA, Guan Y, Halfmann P, Kawaoka Y, Peiris M, Poon LL.

Clin Chem. 2015 Jun;61(6):885-6. doi: 10.1373/clinchem.2015.238204. Epub 2015 Mar 31. No abstract available.

34.

Lack of middle East respiratory syndrome coronavirus transmission from infected camels.

Hemida MG, Al-Naeem A, Perera RA, Chin AW, Poon LL, Peiris M.

Emerg Infect Dis. 2015 Apr;21(4):699-701. doi: 10.3201/eid2104.141949.

35.

Dissemination, divergence and establishment of H7N9 influenza viruses in China.

Lam TT, Zhou B, Wang J, Chai Y, Shen Y, Chen X, Ma C, Hong W, Chen Y, Zhang Y, Duan L, Chen P, Jiang J, Zhang Y, Li L, Poon LL, Webby RJ, Smith DK, Leung GM, Peiris JS, Holmes EC, Guan Y, Zhu H.

Nature. 2015 Jun 4;522(7554):102-5. doi: 10.1038/nature14348. Epub 2015 Mar 11.

PMID:
25762140
36.

Inhalable dry powder formulations of siRNA and pH-responsive peptides with antiviral activity against H1N1 influenza virus.

Liang W, Chow MY, Lau PN, Zhou QT, Kwok PC, Leung GP, Mason AJ, Chan HK, Poon LL, Lam JK.

Mol Pharm. 2015 Mar 2;12(3):910-21. doi: 10.1021/mp500745v. Epub 2015 Jan 30.

PMID:
25599953
37.

Molecular epidemiology of influenza A(H1N1)pdm09 virus among humans and swine, Sri Lanka.

Perera HK, Vijaykrishna D, Premarathna AG, Jayamaha CJ, Wickramasinghe G, Cheung CL, Yeung MF, Poon LL, Perera AK, Barr IG, Guan Y, Peiris M.

Emerg Infect Dis. 2014 Dec;20(12):2080-4. doi: 10.3201/eid2012.140842.

38.

Detection of Novel Reassortant Influenza A (H3N2) and H1N1 2009 Pandemic Viruses in Swine in Hanoi, Vietnam.

Baudon E, Poon LL, Dao TD, Pham NT, Cowling BJ, Peyre M, Nguyen KV, Peiris M.

Zoonoses Public Health. 2015 Sep;62(6):429-34. doi: 10.1111/zph.12164. Epub 2014 Nov 1.

PMID:
25363845
39.

Influenza A viruses with different amino acid residues at PB2-627 display distinct replication properties in vitro and in vivo: revealing the sequence plasticity of PB2-627 position.

Chin AWH, Li OTW, Mok CKP, Ng MKW, Peiris M, Poon LLM.

Virology. 2014 Nov;468-470:545-555. doi: 10.1016/j.virol.2014.09.008. Epub 2014 Sep 28.

40.

Generation and characterization of influenza A viruses with altered polymerase fidelity.

Cheung PP, Watson SJ, Choy KT, Fun Sia S, Wong DD, Poon LL, Kellam P, Guan Y, Malik Peiris JS, Yen HL.

Nat Commun. 2014 Sep 3;5:4794. doi: 10.1038/ncomms5794.

41.

Tropism and replication of Middle East respiratory syndrome coronavirus from dromedary camels in the human respiratory tract: an in-vitro and ex-vivo study.

Chan RW, Hemida MG, Kayali G, Chu DK, Poon LL, Alnaeem A, Ali MA, Tao KP, Ng HY, Chan MC, Guan Y, Nicholls JM, Peiris JS.

Lancet Respir Med. 2014 Oct;2(10):813-22. doi: 10.1016/S2213-2600(14)70158-4. Epub 2014 Aug 28.

PMID:
25174549
42.

Use of fractional factorial design to study the compatibility of viral ribonucleoprotein gene segments of human H7N9 virus and circulating human influenza subtypes.

Chin AW, Mok CK, Zhu H, Guan Y, Peiris JS, Poon LL.

Influenza Other Respir Viruses. 2014 Sep;8(5):580-4. doi: 10.1111/irv.12269. Epub 2014 Jul 9.

43.

Substitution at aspartic acid 1128 in the SARS coronavirus spike glycoprotein mediates escape from a S2 domain-targeting neutralizing monoclonal antibody.

Ng OW, Keng CT, Leung CS, Peiris JS, Poon LL, Tan YJ.

PLoS One. 2014 Jul 14;9(7):e102415. doi: 10.1371/journal.pone.0102415. eCollection 2014.

44.

Expansion of genotypic diversity and establishment of 2009 H1N1 pandemic-origin internal genes in pigs in China.

Liang H, Lam TT, Fan X, Chen X, Zeng Y, Zhou J, Duan L, Tse M, Chan CH, Li L, Leung TY, Yip CH, Cheung CL, Zhou B, Smith DK, Poon LL, Peiris M, Guan Y, Zhu H.

J Virol. 2014 Sep;88(18):10864-74. doi: 10.1128/JVI.01327-14. Epub 2014 Jul 9.

45.

MERS coronavirus in dromedary camel herd, Saudi Arabia.

Hemida MG, Chu DK, Poon LL, Perera RA, Alhammadi MA, Ng HY, Siu LY, Guan Y, Alnaeem A, Peiris M.

Emerg Infect Dis. 2014 Jul;20(7):1231-4. doi: 10.3201/eid2007.140571.

46.

Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity.

Hemida MG, Perera RA, Al Jassim RA, Kayali G, Siu LY, Wang P, Chu KW, Perlman S, Ali MA, Alnaeem A, Guan Y, Poon LL, Saif L, Peiris M.

Euro Surveill. 2014 Jun 12;19(23). pii: 20828.

47.

MERS coronaviruses in dromedary camels, Egypt.

Chu DK, Poon LL, Gomaa MM, Shehata MM, Perera RA, Abu Zeid D, El Rifay AS, Siu LY, Guan Y, Webby RJ, Ali MA, Peiris M, Kayali G.

Emerg Infect Dis. 2014 Jun;20(6):1049-53. doi: 10.3201/eid2006.140299.

48.

A novel molecular test for influenza B virus detection and lineage differentiation.

Wong CK, Tsang GC, Chan KH, Li OT, Peiris M, Poon LL.

J Med Virol. 2014 Dec;86(12):2171-6. doi: 10.1002/jmv.23955. Epub 2014 Apr 24.

49.

Anti-inflammatory and antiviral effects of indirubin derivatives in influenza A (H5N1) virus infected primary human peripheral blood-derived macrophages and alveolar epithelial cells.

Mok CK, Kang SS, Chan RW, Yue PY, Mak NK, Poon LL, Wong RN, Peiris JS, Chan MC.

Antiviral Res. 2014 Jun;106:95-104. doi: 10.1016/j.antiviral.2014.03.019. Epub 2014 Apr 6.

PMID:
24717263
50.

IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection.

Valkenburg SA, Li OT, Mak PW, Mok CK, Nicholls JM, Guan Y, Waldmann TA, Peiris JS, Perera LP, Poon LL.

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5676-81. doi: 10.1073/pnas.1403684111. Epub 2014 Mar 31.

Supplemental Content

Support Center