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Items: 1 to 50 of 206

1.

Multiplex Screening Assay for Identifying Cytotoxic CD8+ T Cell Epitopes.

Poh CM, Zheng J, Channappanavar R, Chang ZW, Nguyen THO, Rénia L, Kedzierska K, Perlman S, Poon LLM.

Front Immunol. 2020 Mar 11;11:400. doi: 10.3389/fimmu.2020.00400. eCollection 2020.

2.

Viral dynamics in mild and severe cases of COVID-19.

Liu Y, Yan LM, Wan L, Xiang TX, Le A, Liu JM, Peiris M, Poon LLM, Zhang W.

Lancet Infect Dis. 2020 Mar 19. pii: S1473-3099(20)30232-2. doi: 10.1016/S1473-3099(20)30232-2. [Epub ahead of print] No abstract available.

PMID:
32199493
3.

Complete Genome Sequence of a 2019 Novel Coronavirus (SARS-CoV-2) Strain Isolated in Nepal.

Sah R, Rodriguez-Morales AJ, Jha R, Chu DKW, Gu H, Peiris M, Bastola A, Lal BK, Ojha HC, Rabaan AA, Zambrano LI, Costello A, Morita K, Pandey BD, Poon LLM.

Microbiol Resour Announc. 2020 Mar 12;9(11). pii: e00169-20. doi: 10.1128/MRA.00169-20.

4.

Heterosubtypic Protection Induced by a Live Attenuated Influenza Virus Vaccine Expressing Galactose-α-1,3-Galactose Epitopes in Infected Cells.

Yan LM, Lau SPN, Poh CM, Chan VSF, Chan MCW, Peiris M, Poon LLM.

mBio. 2020 Mar 3;11(2). pii: e00027-20. doi: 10.1128/mBio.00027-20.

5.

Emergence of a novel human coronavirus threatening human health.

Poon LLM, Peiris M.

Nat Med. 2020 Mar;26(3):317-319. doi: 10.1038/s41591-020-0796-5. No abstract available.

6.

Viral load of SARS-CoV-2 in clinical samples.

Pan Y, Zhang D, Yang P, Poon LLM, Wang Q.

Lancet Infect Dis. 2020 Apr;20(4):411-412. doi: 10.1016/S1473-3099(20)30113-4. Epub 2020 Feb 24. No abstract available.

PMID:
32105638
7.

The first 2019 novel coronavirus case in Nepal.

Bastola A, Sah R, Rodriguez-Morales AJ, Lal BK, Jha R, Ojha HC, Shrestha B, Chu DKW, Poon LLM, Costello A, Morita K, Pandey BD.

Lancet Infect Dis. 2020 Mar;20(3):279-280. doi: 10.1016/S1473-3099(20)30067-0. Epub 2020 Feb 10. No abstract available.

PMID:
32057299
8.

Molecular Diagnosis of a Novel Coronavirus (2019-nCoV) Causing an Outbreak of Pneumonia.

Chu DKW, Pan Y, Cheng SMS, Hui KPY, Krishnan P, Liu Y, Ng DYM, Wan CKC, Yang P, Wang Q, Peiris M, Poon LLM.

Clin Chem. 2020 Jan 31. pii: hvaa029. doi: 10.1093/clinchem/hvaa029. [Epub ahead of print]

PMID:
32031583
9.

Assessment of enhanced influenza vaccination finds that FluAd conveys an advantage in mice and older adults.

Kavian N, Hachim A, Li AP, Cohen CA, Chin AW, Poon LL, Fang VJ, Leung NH, Cowling BJ, Valkenburg SA.

Clin Transl Immunology. 2020 Feb 3;9(2):e1107. doi: 10.1002/cti2.1107. eCollection 2020.

10.

Influenza A Virus Infections in Dromedary Camels, Nigeria and Ethiopia, 2015-2017.

Chu DKW, Perera RAPM, Ali A, Oladipo JO, Mamo G, So RTY, Zhou Z, Chor YY, Chan CK, Belay D, Tayachew A, Mengesha M, Regassa F, Lam NT, Poon LLM, Peiris M.

Emerg Infect Dis. 2020 Jan;26(1):173-176. doi: 10.3201/eid2601.191165.

11.

Cross-reactive antibody-dependent cellular cytotoxicity antibodies are increased by recent infection in a household study of influenza transmission.

Valkenburg SA, Fang VJ, Leung NH, Chu DK, Ip DK, Perera RA, Wang Y, Li AP, Peiris JM, Cowling BJ, Poon LL.

Clin Transl Immunology. 2019 Nov 20;8(11):e1092. doi: 10.1002/cti2.1092. eCollection 2019.

12.

Vaccine-induced T cell protection from influenza viruses.

Valkenburg SA, Li OTW, Peiris JSM, Perera LP, Poon LLM.

Hong Kong Med J. 2019 Oct;25 Suppl 7(7):33-36. No abstract available.

13.

Dinucleotide evolutionary dynamics in influenza A virus.

Gu H, Fan RLY, Wang D, Poon LLM.

Virus Evol. 2019 Sep 17;5(2):vez038. doi: 10.1093/ve/vez038. eCollection 2019 Jul.

14.

Diversity of Dromedary Camel Coronavirus HKU23 in African Camels Revealed Multiple Recombination Events among Closely Related Betacoronaviruses of the Subgenus Embecovirus.

So RTY, Chu DKW, Miguel E, Perera RAPM, Oladipo JO, Fassi-Fihri O, Aylet G, Ko RLW, Zhou Z, Cheng MS, Kuranga SA, Roger FL, Chevalier V, Webby RJ, Woo PCY, Poon LLM, Peiris M.

J Virol. 2019 Nov 13;93(23). pii: e01236-19. doi: 10.1128/JVI.01236-19. Print 2019 Dec 1.

PMID:
31534035
15.

On-Demand Droplet Collection for Capturing Single Cells.

Nan L, Lai MYA, Tang MYH, Chan YK, Poon LLM, Shum HC.

Small. 2020 Mar;16(9):e1902889. doi: 10.1002/smll.201902889. Epub 2019 Aug 25.

PMID:
31448532
16.

Reply to 'Reconciling disparate estimates of viral genetic diversity during human influenza infections'.

Poon LLM, Song T, Wentworth DE, Holmes EC, Greenbaum BD, Peiris JSM, Cowling BJ, Ghedin E.

Nat Genet. 2019 Sep;51(9):1301-1303. doi: 10.1038/s41588-019-0486-8. No abstract available.

PMID:
31406345
17.

Risk Assessment of the Tropism and Pathogenesis of the Highly Pathogenic Avian Influenza A/H7N9 Virus Using Ex Vivo and In Vitro Cultures of Human Respiratory Tract.

Chan LLY, Hui KPY, Kuok DIT, Bui CHT, Ng KC, Mok CKP, Yang ZF, Guan W, Poon LLM, Zhong N, Peiris JSM, Nicholls JM, Chan MCW.

J Infect Dis. 2019 Jul 19;220(4):578-588. doi: 10.1093/infdis/jiz165.

PMID:
31001638
18.

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.

Laursen NS, Friesen RHE, Zhu X, Jongeneelen M, Blokland S, Vermond J, van Eijgen A, Tang C, van Diepen H, Obmolova G, van der Neut Kolfschoten M, Zuijdgeest D, Straetemans R, Hoffman RMB, Nieusma T, Pallesen J, Turner HL, Bernard SM, Ward AB, Luo J, Poon LLM, Tretiakova AP, Wilson JM, Limberis MP, Vogels R, Brandenburg B, Kolkman JA, Wilson IA.

Science. 2018 Nov 2;362(6414):598-602. doi: 10.1126/science.aaq0620.

19.

Combined use of live-attenuated and inactivated influenza vaccines to enhance heterosubtypic protection.

Yan LM, Li OTW, Poh CM, Perera RAPM, Valkenburg SA, Peiris M, Poon LLM.

Virology. 2018 Dec;525:73-82. doi: 10.1016/j.virol.2018.09.007. Epub 2018 Sep 21.

20.

Mini viral RNAs act as innate immune agonists during influenza virus infection.

Te Velthuis AJW, Long JC, Bauer DLV, Fan RLY, Yen HL, Sharps J, Siegers JY, Killip MJ, French H, Oliva-Martín MJ, Randall RE, de Wit E, van Riel D, Poon LLM, Fodor E.

Nat Microbiol. 2018 Nov;3(11):1234-1242. doi: 10.1038/s41564-018-0240-5. Epub 2018 Sep 17.

21.

Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016.

So RT, Perera RA, Oladipo JO, Chu DK, Kuranga SA, Chan KH, Lau EH, Cheng SM, Poon LL, Webby RJ, Peiris M.

Euro Surveill. 2018 Aug;23(32). doi: 10.2807/1560-7917.ES.2018.23.32.1800175.

22.

The Hurdles From Bench to Bedside in the Realization and Implementation of a Universal Influenza Vaccine.

Valkenburg SA, Leung NHL, Bull MB, Yan LM, Li APY, Poon LLM, Cowling BJ.

Front Immunol. 2018 Jul 2;9:1479. doi: 10.3389/fimmu.2018.01479. eCollection 2018. Review.

23.

Circulation of Influenza A(H5N8) Virus, Saudi Arabia.

Al-Ghadeer H, Chu DKW, Rihan EMA, Abd-Allah EA, Gu H, Chin AWH, Qasim IA, Aldoweriej A, Alharbi SS, Al-Aqil MA, Al-Sahaf A, Abdel Rahman SS, Aljassem AH, Abdul-Al A, Aljasir MR, Alhammad YMO, Kasem S, Peiris M, Zaki AZSA, Poon LLM.

Emerg Infect Dis. 2018 Oct;24(10):1961-1964. doi: 10.3201/eid2410.180846. Epub 2018 Oct 17.

24.

Protection by universal influenza vaccine is mediated by memory CD4 T cells.

Valkenburg SA, Li OTW, Li A, Bull M, Waldmann TA, Perera LP, Peiris M, Poon LLM.

Vaccine. 2018 Jul 5;36(29):4198-4206. doi: 10.1016/j.vaccine.2018.06.007. Epub 2018 Jun 7.

PMID:
29887326
25.

Replicative virus shedding in the respiratory tract of patients with Middle East respiratory syndrome coronavirus infection.

Park WB, Poon LLM, Choi SJ, Choe PG, Song KH, Bang JH, Kim ES, Kim HB, Park SW, Kim NJ, Peiris M, Oh MD.

Int J Infect Dis. 2018 Jul;72:8-10. doi: 10.1016/j.ijid.2018.05.003. Epub 2018 May 9.

26.

MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity.

Chu DKW, Hui KPY, Perera RAPM, Miguel E, Niemeyer D, Zhao J, Channappanavar R, Dudas G, Oladipo JO, Traoré A, Fassi-Fihri O, Ali A, Demissié GF, Muth D, Chan MCW, Nicholls JM, Meyerholz DK, Kuranga SA, Mamo G, Zhou Z, So RTY, Hemida MG, Webby RJ, Roger F, Rambaut A, Poon LLM, Perlman S, Drosten C, Chevalier V, Peiris M.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3144-3149. doi: 10.1073/pnas.1718769115. Epub 2018 Mar 5.

27.

Identification of influenza polymerase inhibitors targeting C-terminal domain of PA through surface plasmon resonance screening.

Lo CY, Li OT, Tang WP, Hu C, Wang GX, Ngo JC, Wan DC, Poon LL, Shaw PC.

Sci Rep. 2018 Feb 2;8(1):2280. doi: 10.1038/s41598-018-20772-9.

28.

Immune Responses to Twice-Annual Influenza Vaccination in Older Adults in Hong Kong.

Tam YH, Valkenburg SA, Perera RAPM, Wong JHF, Fang VJ, Ng TWY, Kwong ASK, Tsui WWS, Ip DKM, Poon LLM, Chau CKV, Barr IG, Peiris JSM, Cowling BJ.

Clin Infect Dis. 2018 Mar 5;66(6):904-912. doi: 10.1093/cid/cix900.

PMID:
29069368
29.

Cross-sectional study of MERS-CoV-specific RNA and antibodies in animals that have had contact with MERS patients in Saudi Arabia.

Kasem S, Qasim I, Al-Hufofi A, Hashim O, Alkarar A, Abu-Obeida A, Gaafer A, Elfadil A, Zaki A, Al-Romaihi A, Babekr N, El-Harby N, Hussien R, Al-Sahaf A, Al-Doweriej A, Bayoumi F, Poon LLM, Chu DKW, Peiris M, Perera RAPM.

J Infect Public Health. 2018 May - Jun;11(3):331-338. doi: 10.1016/j.jiph.2017.09.022. Epub 2017 Oct 6.

30.

Characterization of influenza A viruses with polymorphism in PB2 residues 701 and 702.

Chin AWH, Leong NKC, Nicholls JM, Poon LLM.

Sci Rep. 2017 Sep 12;7(1):11361. doi: 10.1038/s41598-017-11625-y.

31.

A46 MERS-CoV in Arabian camels in Africa and Central Asia.

Chu DKW, Chan SMS, Perera RAPM, Miguel E, Roger F, Chevalier V, Poon LLM, Peiris M.

Virus Evol. 2017 Mar 5;3(Suppl 1). pii: vew036.045. doi: 10.1093/ve/vew036.045. eCollection 2017 Mar. No abstract available.

32.

Longitudinal study of Middle East Respiratory Syndrome coronavirus infection in dromedary camel herds in Saudi Arabia, 2014-2015.

Hemida MG, Alnaeem A, Chu DK, Perera RA, Chan SM, Almathen F, Yau E, Ng BC, Webby RJ, Poon LL, Peiris M.

Emerg Microbes Infect. 2017 Jun 21;6(6):e56. doi: 10.1038/emi.2017.44.

33.

Identification of influenza polymerase inhibitors targeting polymerase PB2 cap-binding domain through virtual screening.

Liu M, Lo CY, Wang G, Chow HF, Ngo JC, Wan DC, Poon LL, Shaw PC.

Antiviral Res. 2017 Aug;144:186-195. doi: 10.1016/j.antiviral.2017.06.009. Epub 2017 Jun 16.

PMID:
28629986
34.

MERS-CoV Antibody Responses 1 Year after Symptom Onset, South Korea, 2015.

Choe PG, Perera RAPM, Park WB, Song KH, Bang JH, Kim ES, Kim HB, Ko LWR, Park SW, Kim NJ, Lau EHY, Poon LLM, Peiris M, Oh MD.

Emerg Infect Dis. 2017 Jul;23(7):1079-1084. doi: 10.3201/eid2307.170310. Epub 2017 Jul 15.

35.

Coronavirus infections in horses in Saudi Arabia and Oman.

Hemida MG, Chu DKW, Perera RAPM, Ko RLW, So RTY, Ng BCY, Chan SMS, Chu S, Alnaeem AA, Alhammadi MA, Webby RJ, Poon LLM, Balasuriya UBR, Peiris M.

Transbound Emerg Dis. 2017 Dec;64(6):2093-2103. doi: 10.1111/tbed.12630. Epub 2017 Mar 13.

PMID:
28296228
36.

Preexisting Antibody-Dependent Cellular Cytotoxicity-Activating Antibody Responses Are Stable Longitudinally and Cross-reactive Responses Are Not Boosted by Recent Influenza Exposure.

Valkenburg SA, Zhang Y, Chan KY, Leung K, Wu JT, Poon LL.

J Infect Dis. 2016 Oct 15;214(8):1159-63. doi: 10.1093/infdis/jiw346. Epub 2016 Aug 4.

37.

Age-specific genetic and antigenic variations of influenza A viruses in Hong Kong, 2013-2014.

Cao P, Wong CM, Chan KH, Wang X, Chan KP, Peiris JS, Poon LL, Yang L.

Sci Rep. 2016 Jul 25;6:30260. doi: 10.1038/srep30260.

38.
39.

Stalking influenza by vaccination with pre-fusion headless HA mini-stem.

Valkenburg SA, Mallajosyula VV, Li OT, Chin AW, Carnell G, Temperton N, Varadarajan R, Poon LL.

Sci Rep. 2016 Mar 7;6:22666. doi: 10.1038/srep22666.

40.

Quantifying influenza virus diversity and transmission in humans.

Poon LL, Song T, Rosenfeld R, Lin X, Rogers MB, Zhou B, Sebra R, Halpin RA, Guan Y, Twaddle A, DePasse JV, Stockwell TB, Wentworth DE, Holmes EC, Greenbaum B, Peiris JS, Cowling BJ, Ghedin E.

Nat Genet. 2016 Feb;48(2):195-200. doi: 10.1038/ng.3479. Epub 2016 Jan 4.

41.

Recombinant influenza virus with a pandemic H2N2 polymerase complex has a higher adaptive potential than one with seasonal H2N2 polymerase complex.

Chin AWH, Yen HL, Krauss S, Webby RJ, Poon LLM.

J Gen Virol. 2016 Mar;97(3):611-619. doi: 10.1099/jgv.0.000385. Epub 2015 Dec 24.

42.

Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels in Nigeria, 2015.

Chu DK, Oladipo JO, Perera RA, Kuranga SA, Chan SM, Poon LL, Peiris M.

Euro Surveill. 2015;20(49). doi: 10.2807/1560-7917.ES.2015.20.49.30086.

43.

Asymptomatic MERS-CoV Infection in Humans Possibly Linked to Infected Dromedaries Imported from Oman to United Arab Emirates, May 2015.

Al Hammadi ZM, Chu DK, Eltahir YM, Al Hosani F, Al Mulla M, Tarnini W, Hall AJ, Perera RA, Abdelkhalek MM, Peiris JS, Al Muhairi SS, Poon LL.

Emerg Infect Dis. 2015 Dec;21(12):2197-200. doi: 10.3201/eid2112.151132.

44.

Comparison of serological assays in human Middle East respiratory syndrome (MERS)-coronavirus infection.

Park SW, Perera RA, Choe PG, Lau EH, Choi SJ, Chun JY, Oh HS, Song KH, Bang JH, Kim ES, Kim HB, Park WB, Kim NJ, Poon LL, Peiris M, Oh MD.

Euro Surveill. 2015;20(41). doi: 10.2807/1560-7917.ES.2015.20.41.30042.

45.

Evidence for an Ancestral Association of Human Coronavirus 229E with Bats.

Corman VM, Baldwin HJ, Tateno AF, Zerbinati RM, Annan A, Owusu M, Nkrumah EE, Maganga GD, Oppong S, Adu-Sarkodie Y, Vallo P, da Silva Filho LV, Leroy EM, Thiel V, van der Hoek L, Poon LL, Tschapka M, Drosten C, Drexler JF.

J Virol. 2015 Dec;89(23):11858-70. doi: 10.1128/JVI.01755-15. Epub 2015 Sep 16.

46.

Generation of Live Attenuated Influenza Virus by Using Codon Usage Bias.

Fan RL, Valkenburg SA, Wong CK, Li OT, Nicholls JM, Rabadan R, Peiris JS, Poon LL.

J Virol. 2015 Nov;89(21):10762-73. doi: 10.1128/JVI.01443-15. Epub 2015 Aug 12.

47.

Transmission of H7N9 Influenza Viruses with a Polymorphism at PB2 Residue 627 in Chickens and Ferrets.

Luk GS, Leung CY, Sia SF, Choy KT, Zhou J, Ho CC, Cheung PP, Lee EF, Wai CK, Li PC, Ip SM, Poon LL, Lindsley WG, Peiris M, Yen HL.

J Virol. 2015 Oct;89(19):9939-51. doi: 10.1128/JVI.01444-15. Epub 2015 Jul 22.

48.

Absence of MERS-Coronavirus in Bactrian Camels, Southern Mongolia, November 2014.

Chan SM, Damdinjav B, Perera RA, Chu DK, Khishgee B, Enkhbold B, Poon LL, Peiris M.

Emerg Infect Dis. 2015 Jul;21(7):1269-71. doi: 10.3201/eid2107.150178. No abstract available.

49.

Pseudoparticle neutralization assay for detecting ebola- neutralizing antibodies in biosafety level 2 settings.

Chin AW, Perera RA, Guan Y, Halfmann P, Kawaoka Y, Peiris M, Poon LL.

Clin Chem. 2015 Jun;61(6):885-6. doi: 10.1373/clinchem.2015.238204. Epub 2015 Mar 31. No abstract available.

PMID:
25829407
50.

Lack of middle East respiratory syndrome coronavirus transmission from infected camels.

Hemida MG, Al-Naeem A, Perera RA, Chin AW, Poon LL, Peiris M.

Emerg Infect Dis. 2015 Apr;21(4):699-701. doi: 10.3201/eid2104.141949.

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