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Items: 8

1.

Improving biophysical properties of a bispecific antibody scaffold to aid developability: quality by molecular design.

Von Kreudenstein TS, Escobar-Carbrera E, Lario PI, D'Angelo I, Brault K, Kelly J, Durocher Y, Baardsnes J, Woods RJ, Xie MH, Girod PA, Suits MD, Boulanger MJ, Poon DK, Ng GY, Dixit SB.

MAbs. 2013 Sep-Oct;5(5):646-54. doi: 10.4161/mabs.25632. Epub 2013 Jul 8.

2.

Probing electrostatic interactions along the reaction pathway of a glycoside hydrolase: histidine characterization by NMR spectroscopy.

Schubert M, Poon DK, Wicki J, Tarling CA, Kwan EM, Nielsen JE, Withers SG, McIntosh LP.

Biochemistry. 2007 Jun 26;46(25):7383-95. Epub 2007 Jun 5.

PMID:
17547373
3.

NMR spectroscopic characterization of a beta-(1,4)-glycosidase along its reaction pathway: stabilization upon formation of the glycosyl-enzyme intermediate.

Poon DK, Ludwiczek ML, Schubert M, Kwan EM, Withers SG, McIntosh LP.

Biochemistry. 2007 Feb 20;46(7):1759-70. Epub 2007 Jan 25.

PMID:
17253772
4.

Unambiguous determination of the ionization state of a glycoside hydrolase active site lysine by 1H-15N heteronuclear correlation spectroscopy.

Poon DK, Schubert M, Au J, Okon M, Withers SG, McIntosh LP.

J Am Chem Soc. 2006 Dec 6;128(48):15388-9.

PMID:
17132001
5.
6.

Gas phase noncovalent protein complexes that retain solution binding properties: Binding of xylobiose inhibitors to the beta-1, 4 exoglucanase from cellulomonas fimi.

Tesić M, Wicki J, Poon DK, Withers SG, Douglas DJ.

J Am Soc Mass Spectrom. 2007 Jan;18(1):64-73. Epub 2006 Sep 26.

7.

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