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Items: 1 to 50 of 105

1.

Gene expression profiles in human peripheral blood mononuclear cells as biomarkers for nutritional in vitro and in vivo investigations.

Hofmann T, Klenow S, Borowicki A, Gill CI, Pool-Zobel BL, Glei M.

Genes Nutr. 2010 Dec;5(4):309-19. doi: 10.1007/s12263-010-0170-1. Epub 2010 Feb 9.

2.

Increasing fish consumption does not affect genotoxicity markers in the colon in an intervention study.

Pot GK, Habermann N, Majsak-Newman G, Harvey LJ, Geelen A, Przybylska-Philips K, Nagengast FM, Witteman BJ, van de Meeberg PC, Hart AR, Schaafsma G, Hooiveld G, Glei M, Lund EK, Pool-Zobel BL, Kampman E.

Carcinogenesis. 2010 Jun;31(6):1087-91. doi: 10.1093/carcin/bgp255. Epub 2009 Oct 27.

PMID:
19861650
3.

Effects of fatty acids on metabolism and cell growth of human colon cell lines of different transformation state.

Habermann N, Christian B, Luckas B, Pool-Zobel BL, Lund EK, Glei M.

Biofactors. 2009 Sep-Oct;35(5):460-7. doi: 10.1002/biof.60.

PMID:
19798733
4.

Modulation of detoxification enzymes by watercress: in vitro and in vivo investigations in human peripheral blood cells.

Hofmann T, Kuhnert A, Schubert A, Gill C, Rowland IR, Pool-Zobel BL, Glei M.

Eur J Nutr. 2009 Dec;48(8):483-91. doi: 10.1007/s00394-009-0039-5. Epub 2009 Jul 28.

PMID:
19636603
5.

Influence of inorganic and organic iron compounds on parameters of cell growth and survival in human colon cells.

Klenow S, Pool-Zobel BL, Glei M.

Toxicol In Vitro. 2009 Apr;23(3):400-7.

PMID:
19444923
6.

Does an extract of carob (Ceratonia siliqua L.) have chemopreventive potential related to oxidative stress and drug metabolism in human colon cells?

Klenow S, Jahns F, Pool-Zobel BL, Glei M.

J Agric Food Chem. 2009 Apr 8;57(7):2999-3004. doi: 10.1021/jf802872b.

PMID:
19296575
7.

Fermentation products of inulin-type fructans reduce proliferation and induce apoptosis in human colon tumour cells of different stages of carcinogenesis.

Munjal U, Glei M, Pool-Zobel BL, Scharlau D.

Br J Nutr. 2009 Sep;102(5):663-71. doi: 10.1017/S0007114509274770. Epub 2009 Feb 27.

PMID:
19250571
8.

Modulation of gene expression in eicosapentaenoic acid and docosahexaenoic acid treated human colon adenoma cells.

Habermann N, Lund EK, Pool-Zobel BL, Glei M.

Genes Nutr. 2009 Mar;4(1):73-6. doi: 10.1007/s12263-009-0112-y. Epub 2009 Feb 21.

9.

Intervention with cloudy apple juice results in altered biological activities of ileostomy samples collected from individual volunteers.

Veeriah S, Balavenkatraman KK, Böhmer F, Kahle K, Glei M, Richling E, Scheppach W, Pool-Zobel BL.

Eur J Nutr. 2008 Aug;47(5):226-34. doi: 10.1007/s00394-008-0726-7. Epub 2008 Jul 17.

PMID:
18636219
10.

Antioxidant effectiveness of phenolic apple juice extracts and their gut fermentation products in the human colon carcinoma cell line caco-2.

Bellion P, Hofmann T, Pool-Zobel BL, Will F, Dietrich H, Knaup B, Richling E, Baum M, Eisenbrand G, Janzowski C.

J Agric Food Chem. 2008 Aug 13;56(15):6310-7. doi: 10.1021/jf8005068. Epub 2008 Jul 15.

PMID:
18624411
11.

Apple polyphenols modulate expression of selected genes related to toxicological defence and stress response in human colon adenoma cells.

Veeriah S, Miene C, Habermann N, Hofmann T, Klenow S, Sauer J, Böhmer F, Wölfl S, Pool-Zobel BL.

Int J Cancer. 2008 Jun 15;122(12):2647-55. doi: 10.1002/ijc.23440.

12.

Use of Comet-FISH in the study of DNA damage and repair: review.

Glei M, Hovhannisyan G, Pool-Zobel BL.

Mutat Res. 2009 Jan-Feb;681(1):33-43. doi: 10.1016/j.mrrev.2008.01.006. Epub 2008 Jan 31. Review.

PMID:
18304859
13.

Histone-deacetylase inhibition and butyrate formation: Fecal slurry incubations with apple pectin and apple juice extracts.

Waldecker M, Kautenburger T, Daumann H, Veeriah S, Will F, Dietrich H, Pool-Zobel BL, Schrenk D.

Nutrition. 2008 Apr;24(4):366-74. doi: 10.1016/j.nut.2007.12.013. Epub 2008 Feb 11.

PMID:
18262392
14.

Effects of carrot and tomato juice consumption on faecal markers relevant to colon carcinogenesis in humans.

Schnäbele K, Briviba K, Bub A, Roser S, Pool-Zobel BL, Rechkemmer G.

Br J Nutr. 2008 Mar;99(3):606-13. doi: 10.1017/S0007114507819143.

PMID:
18254985
15.

Overview of experimental data on reduction of colorectal cancer risk by inulin-type fructans.

Pool-Zobel BL, Sauer J.

J Nutr. 2007 Nov;137(11 Suppl):2580S-2584S. doi: 10.1093/jn/137.11.2580S. Review.

PMID:
17951507
16.

Carob fibre compounds modulate parameters of cell growth differently in human HT29 colon adenocarcinoma cells than in LT97 colon adenoma cells.

Klenow S, Glei M, Haber B, Owen R, Pool-Zobel BL.

Food Chem Toxicol. 2008 Apr;46(4):1389-97. Epub 2007 Sep 11.

PMID:
17950517
17.

Ursodeoxycholic acid intervention in patients with familial adenomatous polyposis: a pilot study.

Berkhout M, Roelofs HM, Friederich P, van Schaik A, Gosens MJ, Marian B, Pool-Zobel BL, van Krieken JH, Peters WH, Nagengast FM.

Transl Res. 2007 Sep;150(3):147-9. Epub 2007 May 25. No abstract available.

PMID:
17761365
18.

Fecal water as a non-invasive biomarker in nutritional intervention: comparison of preparation methods and refinement of different endpoints.

Klinder A, Karlsson PC, Clune Y, Hughes R, Glei M, Rafter JJ, Rowland I, Collins JK, Pool-Zobel BL.

Nutr Cancer. 2007;57(2):158-67.

PMID:
17571949
19.

Bread enriched with green coffee extract has chemoprotective and antigenotoxic activities in human cells.

Glei M, Kirmse A, Habermann N, Persin C, Pool-Zobel BL.

Nutr Cancer. 2006;56(2):182-92.

PMID:
17474864
20.

Physiological concentrations of butyrate favorably modulate genes of oxidative and metabolic stress in primary human colon cells.

Sauer J, Richter KK, Pool-Zobel BL.

J Nutr Biochem. 2007 Nov;18(11):736-45. Epub 2007 Apr 16.

PMID:
17434725
22.

Apple polyphenols and products formed in the gut differently inhibit survival of human cell lines derived from colon adenoma (LT97) and carcinoma (HT29).

Veeriah S, Hofmann T, Glei M, Dietrich H, Will F, Schreier P, Knaup B, Pool-Zobel BL.

J Agric Food Chem. 2007 Apr 18;55(8):2892-900. Epub 2007 Mar 23.

PMID:
17378580
23.

Blood mononucleocytes are sensitive to the DNA damaging effects of iron overload--in vitro and ex vivo results with human and rat cells.

Park E, Glei M, Knöbel Y, Pool-Zobel BL.

Mutat Res. 2007 Jun 1;619(1-2):59-67. Epub 2007 Feb 6.

PMID:
17349663
24.

Influence of prebiotics and antioxidants in bread on the immune system, antioxidative status and antioxidative capacity in male smokers and non-smokers.

Seidel C, Boehm V, Vogelsang H, Wagner A, Persin C, Glei M, Pool-Zobel BL, Jahreis G.

Br J Nutr. 2007 Feb;97(2):349-56.

PMID:
17298705
25.

Comet fluorescence in situ hybridization analysis for oxidative stress-induced DNA damage in colon cancer relevant genes.

Glei M, Schaeferhenrich A, Claussen U, Kuechler A, Liehr T, Weise A, Marian B, Sendt W, Pool-Zobel BL.

Toxicol Sci. 2007 Apr;96(2):279-84. Epub 2006 Dec 27.

PMID:
17192441
26.

Ferric iron is genotoxic in non-transformed and preneoplastic human colon cells.

Knöbel Y, Weise A, Glei M, Sendt W, Claussen U, Pool-Zobel BL.

Food Chem Toxicol. 2007 May;45(5):804-11. Epub 2006 Nov 7.

PMID:
17157427
27.

Intervention with polyphenol-rich fruit juices results in an elevation of glutathione S-transferase P1 (hGSTP1) protein expression in human leucocytes of healthy volunteers.

Hofmann T, Liegibel U, Winterhalter P, Bub A, Rechkemmer G, Pool-Zobel BL.

Mol Nutr Food Res. 2006 Dec;50(12):1191-200.

PMID:
17131458
29.
30.
31.

Equol: a comparison of the effects of the racemic compound with that of the purified S-enantiomer on the growth, invasion, and DNA integrity of breast and prostate cells in vitro.

Magee PJ, Raschke M, Steiner C, Duffin JG, Pool-Zobel BL, Jokela T, Wahala K, Rowland IR.

Nutr Cancer. 2006;54(2):232-42.

PMID:
16898868
32.

Uranyl nitrilotriacetate, a stabilized salt of uranium, is genotoxic in nontransformed human colon cells and in the human colon adenoma cell line LT97.

Knöbel Y, Glei M, Weise A, Osswald K, Schäferhenrich A, Richter KK, Claussen U, Pool-Zobel BL.

Toxicol Sci. 2006 Oct;93(2):286-97. Epub 2006 Jul 13.

PMID:
16840563
33.

Genistein protects prostate cells against hydrogen peroxide-induced DNA damage and induces expression of genes involved in the defence against oxidative stress.

Raschke M, Rowland IR, Magee PJ, Pool-Zobel BL.

Carcinogenesis. 2006 Nov;27(11):2322-30. Epub 2006 Jun 13.

PMID:
16774941
34.

DEP-1 protein tyrosine phosphatase inhibits proliferation and migration of colon carcinoma cells and is upregulated by protective nutrients.

Balavenkatraman KK, Jandt E, Friedrich K, Kautenburger T, Pool-Zobel BL, Ostman A, Böhmer FD.

Oncogene. 2006 Oct 12;25(47):6319-24. Epub 2006 May 8.

PMID:
16682945
35.
36.

Ferric iron increases ROS formation, modulates cell growth and enhances genotoxic damage by 4-hydroxynonenal in human colon tumor cells.

Knöbel Y, Glei M, Osswald K, Pool-Zobel BL.

Toxicol In Vitro. 2006 Sep;20(6):793-800. Epub 2006 Jan 18.

PMID:
16412607
37.

Apple flavonoids inhibit growth of HT29 human colon cancer cells and modulate expression of genes involved in the biotransformation of xenobiotics.

Veeriah S, Kautenburger T, Habermann N, Sauer J, Dietrich H, Will F, Pool-Zobel BL.

Mol Carcinog. 2006 Mar;45(3):164-74.

PMID:
16369997
38.

Hemoglobin and hemin induce DNA damage in human colon tumor cells HT29 clone 19A and in primary human colonocytes.

Glei M, Klenow S, Sauer J, Wegewitz U, Richter K, Pool-Zobel BL.

Mutat Res. 2006 Feb 22;594(1-2):162-71. Epub 2005 Oct 13.

PMID:
16226281
39.

The main catechin of green tea, (-)-epigallocatechin-3-gallate (EGCG), reduces bleomycin-induced DNA damage in human leucocytes.

Glei M, Pool-Zobel BL.

Toxicol In Vitro. 2006 Apr;20(3):295-300. Epub 2005 Sep 26.

PMID:
16188420
40.

2-Dodecylcyclobutanone, a radiolytic product of palmitic acid, is genotoxic in primary human colon cells and in cells from preneoplastic lesions.

Knoll N, Weise A, Claussen U, Sendt W, Marian B, Glei M, Pool-Zobel BL.

Mutat Res. 2006 Feb 22;594(1-2):10-9. Epub 2005 Sep 8.

PMID:
16153665
41.

The gut fermentation product butyrate, a chemopreventive agent, suppresses glutathione S-transferase theta (hGSTT1) and cell growth more in human colon adenoma (LT97) than tumor (HT29) cells.

Kautenburger T, Beyer-Sehlmeyer G, Festag G, Haag N, Kühler S, Küchler A, Weise A, Marian B, Peters WH, Liehr T, Claussen U, Pool-Zobel BL.

J Cancer Res Clin Oncol. 2005 Oct;131(10):692-700. Epub 2005 Oct 20.

PMID:
16133571
42.

Assessment of DNA damage and its modulation by dietary and genetic factors in smokers using the Comet assay: a biomarker model.

Glei M, Habermann N, Osswald K, Seidel C, Persin C, Jahreis G, Pool-Zobel BL.

Biomarkers. 2005 Mar-Jun;10(2-3):203-17.

PMID:
16076733
43.

Basal colon crypt cells are more sensitive than surface cells toward hydrogen peroxide, a factor of oxidative stress.

Oberreuther-Moschner DL, Rechkemmer G, Pool-Zobel BL.

Toxicol Lett. 2005 Dec 15;159(3):212-8. Epub 2005 Jun 23.

PMID:
15979256
44.

Inulin-type fructans and reduction in colon cancer risk: review of experimental and human data.

Pool-Zobel BL.

Br J Nutr. 2005 Apr;93 Suppl 1:S73-90. Review.

PMID:
15877900
45.

Genotoxicity of 4-hydroxy-2-nonenal in human colon tumor cells is associated with cellular levels of glutathione and the modulation of glutathione S-transferase A4 expression by butyrate.

Knoll N, Ruhe C, Veeriah S, Sauer J, Glei M, Gallagher EP, Pool-Zobel BL.

Toxicol Sci. 2005 Jul;86(1):27-35. Epub 2005 Apr 13.

PMID:
15829614
46.

Butyrate may enhance toxicological defence in primary, adenoma and tumor human colon cells by favourably modulating expression of glutathione S-transferases genes, an approach in nutrigenomics.

Pool-Zobel BL, Selvaraju V, Sauer J, Kautenburger T, Kiefer J, Richter KK, Soom M, Wölfl S.

Carcinogenesis. 2005 Jun;26(6):1064-76. Epub 2005 Mar 3.

PMID:
15746163
48.
49.
50.

Multitude multicolor chromosome banding (mMCB) - a comprehensive one-step multicolor FISH banding method.

Weise A, Heller A, Starke H, Mrasek K, Kuechler A, Pool-Zobel BL, Claussen U, Liehr T.

Cytogenet Genome Res. 2003;103(1-2):34-9.

PMID:
15004461

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