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Items: 1 to 50 of 209

1.

Risk of colorectal polyps and of malignancies in asymptomatic carriers of mutations in the main DNA mismatch repair genes.

Ponz de Leon M, Pedroni M, Pezzi A, Sulce B, Roncucci L, Domati F, Rossi G, Reggiani Bonetti L.

Scand J Gastroenterol. 2018 Jan;53(1):31-37. doi: 10.1080/00365521.2017.1386794. Epub 2017 Oct 12.

PMID:
29025352
2.

Nonalcoholic fatty liver disease and COPD: is it time to cross the diaphragm?

Lonardo A, Nascimbeni F, Ponz de Leon M.

Eur Respir J. 2017 Jun 8;49(6). pii: 1700546. doi: 10.1183/13993003.00546-2017. Print 2017 Jun. No abstract available.

3.

Aberrant DNA methylation profiles of inherited and sporadic colorectal cancer.

Sahnane N, Magnoli F, Bernasconi B, Tibiletti MG, Romualdi C, Pedroni M, Ponz de Leon M, Magnani G, Reggiani-Bonetti L, Bertario L, Signoroni S, Capella C, Sessa F, Furlan D; AIFEG.

Clin Epigenetics. 2015 Dec 21;7:131. doi: 10.1186/s13148-015-0165-2. eCollection 2015.

4.

Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis.

Tricarico R, Cortellino S, Riccio A, Jagmohan-Changur S, Van der Klift H, Wijnen J, Turner D, Ventura A, Rovella V, Percesepe A, Lucci-Cordisco E, Radice P, Bertario L, Pedroni M, Ponz de Leon M, Mancuso P, Devarajan K, Cai KQ, Klein-Szanto AJ, Neri G, Møller P, Viel A, Genuardi M, Fodde R, Bellacosa A.

Oncotarget. 2015 Dec 15;6(40):42892-904. doi: 10.18632/oncotarget.5740.

5.

MLH1 constitutional and somatic methylation in patients with MLH1 negative tumors fulfilling the revised Bethesda criteria.

Crucianelli F, Tricarico R, Turchetti D, Gorelli G, Gensini F, Sestini R, Giunti L, Pedroni M, Ponz de Leon M, Civitelli S, Genuardi M.

Epigenetics. 2014 Oct;9(10):1431-8. doi: 10.4161/15592294.2014.970080.

6.

An unusual case of familial adenomatous polyposis with very early symptom occurrence.

Ponz de Leon M, Bianchini MA, Reggiani-Bonetti L, Pedroni M, Di Gregorio C, Merighi A, Rossi G, Magnani G, Domati F, Cacciari A.

Fam Cancer. 2014 Sep;13(3):375-80. doi: 10.1007/s10689-014-9718-3.

PMID:
24770791
7.

PLZF expression during colorectal cancer development and in normal colorectal mucosa according to body size, as marker of colorectal cancer risk.

Mariani F, Sena P, Magnani G, Mancini S, Palumbo C, Ponz de Leon M, Roncucci L.

ScientificWorldJournal. 2013 Nov 14;2013:630869. doi: 10.1155/2013/630869. eCollection 2013.

8.

Estimates of cancer burden in Emilia-Romagna.

Falcini F, Mancini S, Ravaioli A, Vattiato R, Bucchi L, Ferretti S, Michiara M, Federico M, Ponz de Leon M, Mangone L, Rossi S, Foschi R.

Tumori. 2013 May-Jun;99(3):327-33. doi: 10.1700/1334.14796.

PMID:
24158061
9.

Incidence trend of malignant polyps through the data of a specialized colorectal cancer registry: clinical features and effect of screening.

Reggiani-Bonetti L, Di Gregorio C, Pedroni M, Domati F, Barresi V, Marcheselli L, Ponz de Leon M.

Scand J Gastroenterol. 2013 Nov;48(11):1294-301. doi: 10.3109/00365521.2013.838301. Epub 2013 Sep 30.

PMID:
24073745
10.

Incidence, clinical features and possible etiology of early onset (≤40 years) colorectal neoplasms.

Domati F, Maffei S, Kaleci S, Di Gregorio C, Pedroni M, Roncucci L, Benatti P, Magnani G, Marcheselli L, Bonetti LR, Mariani F, Alberti AM, Rossi V, Ponz de Leon M.

Intern Emerg Med. 2014 Sep;9(6):623-31. doi: 10.1007/s11739-013-0981-3. Epub 2013 Aug 9.

PMID:
23929387
11.

Lymph node evaluation in stage IIA colorectal cancer and its impact on patient prognosis: a population-based study.

Iachetta F, Reggiani Bonetti L, Marcheselli L, Di Gregorio C, Cirilli C, Messinese S, Cervo GL, Postiglione R, Di Emidio K, Pedroni M, Longinotti E, Federico M, Ponz de Leon M.

Acta Oncol. 2013 Nov;52(8):1682-90. doi: 10.3109/0284186X.2013.808376. Epub 2013 Jun 20.

PMID:
23786176
12.

Disease presentation, treatment and survival for Italian colorectal cancer patients: a EUROCARE high resolution study.

Minicozzi P, Kaleci S, Maffei S, Allemani C, Giacomin A, Caldarella A, Iachetta F, Fusco M, Tumino R, Vicentini M, Falcini F, Cesaraccio R, Ponz de Leon M, Sant M.

Eur J Public Health. 2014 Feb;24(1):98-100. doi: 10.1093/eurpub/ckt056. Epub 2013 May 31.

PMID:
23729484
13.

Double heterozygosity for BRCA1 and hMLH1 gene mutations in a 46-year-old woman with five primary tumors.

Pedroni M, Di Gregorio C, Cortesi L, Reggiani Bonetti L, Magnani G, Simone ML, Medici V, Priore Oliva C, Marino M, Ponz de Leon M.

Tech Coloproctol. 2014 Mar;18(3):285-9. doi: 10.1007/s10151-013-1030-y. Epub 2013 May 22.

PMID:
23695190
14.

Colonoscopic surveillance of first-degree relatives of colorectal cancer patients in a faecal occult blood screening programme.

Sassoli de Bianchi P, Campari C, Mancini S, Giuliani O, Landi P, Paterlini L, Naldoni C, Finarelli AC, Falcini F, Ponz de Leon M, Sassatelli R, Borciani E, Fornari F, Gatti G, Zatelli M, Zurlini C, Rossi F, Corradini R, Olivetti R, Manfredi M, Baldazzi P, Nannini R, Zanarini S, Matarese VG, Palmonari C, Triossi O, Gordini S, Vattiato R, Colamartini A, Palazzi M, Severi M, Briganti L, Giovanardi M, Casale C, Bucchi L.

Cancer Epidemiol. 2013 Aug;37(4):469-73. doi: 10.1016/j.canep.2013.04.004. Epub 2013 May 14.

PMID:
23683843
15.

Impact of diabetes on overall and cancer-specific mortality in colorectal cancer patients.

Bella F, Minicozzi P, Giacomin A, Crocetti E, Federico M, Ponz de Leon M, Fusco M, Tumino R, Mangone L, Giuliani O, Budroni M, Sant M.

J Cancer Res Clin Oncol. 2013 Aug;139(8):1303-10. doi: 10.1007/s00432-013-1439-8. Epub 2013 Apr 30.

PMID:
23633003
16.

Cancer risk associated with STK11/LKB1 germline mutations in Peutz-Jeghers syndrome patients: results of an Italian multicenter study.

Resta N, Pierannunzio D, Lenato GM, Stella A, Capocaccia R, Bagnulo R, Lastella P, Susca FC, Bozzao C, Loconte DC, Sabbà C, Urso E, Sala P, Fornasarig M, Grammatico P, Piepoli A, Host C, Turchetti D, Viel A, Memo L, Giunti L, Stigliano V, Varesco L, Bertario L, Genuardi M, Lucci Cordisco E, Tibiletti MG, Di Gregorio C, Andriulli A, Ponz de Leon M; AIFEG.

Dig Liver Dis. 2013 Jul;45(7):606-11. doi: 10.1016/j.dld.2012.12.018. Epub 2013 Feb 15.

PMID:
23415580
17.

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts.

Vasen HF, Blanco I, Aktan-Collan K, Gopie JP, Alonso A, Aretz S, Bernstein I, Bertario L, Burn J, Capella G, Colas C, Engel C, Frayling IM, Genuardi M, Heinimann K, Hes FJ, Hodgson SV, Karagiannis JA, Lalloo F, Lindblom A, Mecklin JP, Møller P, Myrhoj T, Nagengast FM, Parc Y, Ponz de Leon M, Renkonen-Sinisalo L, Sampson JR, Stormorken A, Sijmons RH, Tejpar S, Thomas HJ, Rahner N, Wijnen JT, Järvinen HJ, Möslein G; Mallorca group.

Gut. 2013 Jun;62(6):812-23. doi: 10.1136/gutjnl-2012-304356. Epub 2013 Feb 13.

18.

Looking at differences in stage and treatment of colorectal cancers across Italy: a EUROCARE-5 high resolution study.

Minicozzi P, Caldarella A, Giacomin A, Ponz de Leon M, Cesaraccio R, Falcini F, Fusco M, Iachetta F, Pellegri C, Tumino R, Capocaccia R, Sant M.

Tumori. 2012 Nov;98(6):671-7. doi: 10.1700/1217.13488.

PMID:
23389351
19.

A case of pneumatosis cystoides intestinalis mimicking familial adenomatous polyposis.

Ponz de Leon M, Bertarelli C, Casadei GP, Grilli A, Bacchini P, Pedroni M, Jovine E.

Fam Cancer. 2013 Sep;12(3):573-6. doi: 10.1007/s10689-012-9587-6.

PMID:
23196630
20.

Colorectal carcinoma grading by quantifying poorly differentiated cell clusters is more reproducible and provides more robust prognostic information than conventional grading.

Barresi V, Reggiani Bonetti L, Branca G, Di Gregorio C, Ponz de Leon M, Tuccari G.

Virchows Arch. 2012 Dec;461(6):621-8. doi: 10.1007/s00428-012-1326-8. Epub 2012 Oct 24.

PMID:
23093109
21.

Identification of Lynch syndrome among patients with colorectal cancer.

Moreira L, Balaguer F, Lindor N, de la Chapelle A, Hampel H, Aaltonen LA, Hopper JL, Le Marchand L, Gallinger S, Newcomb PA, Haile R, Thibodeau SN, Gunawardena S, Jenkins MA, Buchanan DD, Potter JD, Baron JA, Ahnen DJ, Moreno V, Andreu M, Ponz de Leon M, Rustgi AK, Castells A; EPICOLON Consortium.

JAMA. 2012 Oct 17;308(15):1555-65. doi: 10.1001/jama.2012.13088.

22.

Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients.

Reggiani Bonetti L, Migaldi M, Caredda E, Boninsegna A, Ponz De Leon M, Di Gregorio C, Barresi V, Scannone D, Danese S, Cittadini A, Sgambato A.

Scand J Gastroenterol. 2012 Oct;47(10):1211-7. Epub 2012 Aug 3.

PMID:
22856425
23.

Matrix metalloproteinases 15 and 19 are stromal regulators of colorectal cancer development from the early stages.

Sena P, Mariani F, Marzona L, Benincasa M, Ponz de Leon M, Palumbo C, Roncucci L.

Int J Oncol. 2012 Jul;41(1):260-6. doi: 10.3892/ijo.2012.1441. Epub 2012 Apr 19.

PMID:
22576687
24.

Clinical outcome of low- and high-risk malignant colorectal polyps: results of a population-based study and meta-analysis of the available literature.

Di Gregorio C, Bonetti LR, de Gaetani C, Pedroni M, Kaleci S, Ponz de Leon M.

Intern Emerg Med. 2014 Mar;9(2):151-60. doi: 10.1007/s11739-012-0772-2. Epub 2012 Mar 27. Review.

PMID:
22451095
25.

Immunohistochemical assessment of lymphovascular invasion in stage I colorectal carcinoma: prognostic relevance and correlation with nodal micrometastases.

Barresi V, Reggiani Bonetti L, Vitarelli E, Di Gregorio C, Ponz de Leon M, Barresi G.

Am J Surg Pathol. 2012 Jan;36(1):66-72. doi: 10.1097/PAS.0b013e31822d3008.

PMID:
21989343
26.

Neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinase-9 (MMP-9) prognostic value in stage I colorectal carcinoma.

Barresi V, Reggiani-Bonetti L, Di Gregorio C, Vitarelli E, Ponz De Leon M, Barresi G.

Pathol Res Pract. 2011 Aug 15;207(8):479-86. doi: 10.1016/j.prp.2011.05.012. Epub 2011 Jul 2.

PMID:
21726963
27.

Long-term survey of patients with curable colorectal cancer with specific reference to the quality of life.

Domati F, Rossi G, Benatti P, Roncucci L, Cirilli C, Ponz de Leon M.

Intern Emerg Med. 2011 Dec;6(6):529-35. doi: 10.1007/s11739-011-0590-y. Epub 2011 Apr 22.

PMID:
21512795
28.

Lymph node micrometastasis and survival of patients with Stage I (Dukes' A) colorectal carcinoma.

Reggiani Bonetti L, Di Gregorio C, De Gaetani C, Pezzi A, Barresi G, Barresi V, Roncucci L, Ponz de Leon M.

Scand J Gastroenterol. 2011 Jul;46(7-8):881-6. doi: 10.3109/00365521.2011.571708. Epub 2011 Apr 15.

PMID:
21492052
29.

Neutrophil gelatinase-associated lipocalin: a new prognostic marker in stage I colorectal carcinoma?

Barresi V, Di Gregorio C, Reggiani-Bonetti L, Ieni A, Ponz-De Leon M, Barresi G.

Hum Pathol. 2011 Nov;42(11):1720-6. doi: 10.1016/j.humpath.2010.05.031. Epub 2011 Mar 21.

PMID:
21420718
30.

Analysis of telomere dynamics in peripheral blood cells from patients with Lynch syndrome.

Bozzao C, Lastella P, Ponz de Leon M, Pedroni M, Di Gregorio C, D'Ovidio FD, Resta N, Prete F, Guanti G, Stella A.

Cancer. 2011 Sep 15;117(18):4325-35. doi: 10.1002/cncr.26022. Epub 2011 Mar 8.

31.

Integrated analysis of unclassified variants in mismatch repair genes.

Pastrello C, Pin E, Marroni F, Bedin C, Fornasarig M, Tibiletti MG, Oliani C, Ponz de Leon M, Urso ED, Della Puppa L, Agostini M, Viel A.

Genet Med. 2011 Feb;13(2):115-24. doi: 10.1097/GIM.0b013e3182011489.

PMID:
21239990
32.

What should we advise about alcohol consumption.

Ponz de Leon M.

Intern Emerg Med. 2011 Feb;6(1):87; author reply 89-90. doi: 10.1007/s11739-010-0487-1. Epub 2010 Nov 30. No abstract available.

PMID:
21116737
33.

[The power of modern medicine: final considerations].

Ponz de Leon M.

Epidemiol Prev. 2010 Jan-Apr;34(1-2):2-3. Italian. No abstract available.

PMID:
20595721
34.

Peutz-Jeghers syndrome: a systematic review and recommendations for management.

Beggs AD, Latchford AR, Vasen HF, Moslein G, Alonso A, Aretz S, Bertario L, Blanco I, Bülow S, Burn J, Capella G, Colas C, Friedl W, Møller P, Hes FJ, Järvinen H, Mecklin JP, Nagengast FM, Parc Y, Phillips RK, Hyer W, Ponz de Leon M, Renkonen-Sinisalo L, Sampson JR, Stormorken A, Tejpar S, Thomas HJ, Wijnen JT, Clark SK, Hodgson SV.

Gut. 2010 Jul;59(7):975-86. doi: 10.1136/gut.2009.198499.

PMID:
20581245
35.

Stage I colorectal carcinoma: VEGF immunohistochemical expression, microvessel density, and their correlation with clinical outcome.

Barresi V, Di Gregorio C, Regiani-Bonetti L, Ponz-De Leon M, Barresi G, Vitarelli E.

Virchows Arch. 2010 Jul;457(1):11-9. doi: 10.1007/s00428-010-0933-5. Epub 2010 Jun 8.

PMID:
20532559
36.

Infliximab-related hepatitis: discussion of a case and review of the literature.

Mancini S, Amorotti E, Vecchio S, Ponz de Leon M, Roncucci L.

Intern Emerg Med. 2010 Jun;5(3):193-200. doi: 10.1007/s11739-009-0342-4. Epub 2010 Jan 27. Review.

PMID:
20107930
37.

[The power of modern medicine].

Ponz de Leon M.

Epidemiol Prev. 2009 May-Jun;33(3):72-4. Italian. No abstract available.

38.

Recommendations to improve identification of hereditary and familial colorectal cancer in Europe.

Vasen HF, Möslein G, Alonso A, Aretz S, Bernstein I, Bertario L, Blanco I, Bulow S, Burn J, Capella G, Colas C, Engel C, Frayling I, Rahner N, Hes FJ, Hodgson S, Mecklin JP, Møller P, Myrhøj T, Nagengast FM, Parc Y, Ponz de Leon M, Renkonen-Sinisalo L, Sampson JR, Stormorken A, Tejpar S, Thomas HJ, Wijnen J, Lubinski J, Järvinen H, Claes E, Heinimann K, Karagiannis JA, Lindblom A, Dove-Edwin I, Müller H.

Fam Cancer. 2010 Jun;9(2):109-15. doi: 10.1007/s10689-009-9291-3. Epub 2009 Sep 18.

PMID:
19763885
39.

Relative role of APC and MUTYH mutations in the pathogenesis of familial adenomatous polyposis.

Pezzi A, Roncucci L, Benatti P, Sassatelli R, Varesco L, Di Gregorio C, Venesio T, Pedroni M, Maffei S, Reggiani Bonetti L, Borsi E, Ferrari M, Martella P, Rossi G, Ponz De Leon M.

Scand J Gastroenterol. 2009;44(9):1092-100. doi: 10.1080/00365520903100481.

PMID:
19593690
40.

Differentiated thyroid carcinoma (DTC) in a young woman with Peutz-Jeghers syndrome: are these two conditions associated?

Zirilli L, Benatti P, Romano S, Roncucci L, Rossi G, Diazzi C, Carani C, Ponz De Leon M, Rochira V.

Exp Clin Endocrinol Diabetes. 2009 May;117(5):234-9. doi: 10.1055/s-0028-1102920. Epub 2009 Feb 20.

PMID:
19235129
41.

Attitude of the Italian general population towards prevention and screening of the most common tumors, with special emphasis on colorectal malignancies.

Domati F, Travlos E, Cirilli C, Rossi G, Benatti P, Marino M, Ponti G, Vandelli M, Valmori S, Oursana A, Pezzi A, Ponz de Leon M.

Intern Emerg Med. 2009 Jun;4(3):213-20. doi: 10.1007/s11739-008-0184-5. Epub 2008 Sep 20.

PMID:
18807148
42.

Epidemiology of colorectal cancer: the 21-year experience of a specialised registry.

Ponz de Leon M, Rossi G, di Gregorio C, De Gaetani C, Rossi F, Ponti G, Pecone L, Pedroni M, Roncucci L, Pezzi A, Benatti P.

Intern Emerg Med. 2007 Dec;2(4):269-79. Epub 2007 Nov 29.

PMID:
18060471
43.

Identification and classification of hereditary nonpolyposis colorectal cancer (Lynch syndrome): adapting old concepts to recent advancements. Report from the Italian Association for the study of Hereditary Colorectal Tumors Consensus Group.

Ponz de Leon M, Bertario L, Genuardi M, Lanza G, Oliani C, Ranzani GN, Rossi GB, Varesco L, Venesio T, Viel A.

Dis Colon Rectum. 2007 Dec;50(12):2126-34. Epub 2007 Sep 27. Review.

PMID:
17899274
44.

Frequency of constitutional MSH6 mutations in a consecutive series of families with clinical suspicion of HNPCC.

Roncari B, Pedroni M, Maffei S, Di Gregorio C, Ponti G, Scarselli A, Losi L, Benatti P, Roncucci L, De Gaetani C, Camellini L, Lucci-Cordisco E, Tricarico R, Genuardi M, Ponz de Leon M.

Clin Genet. 2007 Sep;72(3):230-7.

PMID:
17718861
45.

Preventive war and chemoprevention of cancer.

Ponz de Leon M, Roncucci L.

Intern Emerg Med. 2007 Jun;2(2):156. Epub 2007 Jul 18. No abstract available.

PMID:
17634827
46.

O6-methylguanine-DNA methyltransferase promoter hypermethylation in colorectal carcinogenesis.

Menigatti M, Pedroni M, Verrone AM, Borghi F, Scarselli A, Benatti P, Losi L, Di Gregorio C, Schär P, Marra G, Ponz de Leon M, Roncucci L.

Oncol Rep. 2007 Jun;17(6):1421-7.

47.

Whipple's disease in a father-son pair.

Ponz de Leon M, Borghi A, Ferrara F, Contri M, Roncucci L.

Intern Emerg Med. 2006;1(3):254-6. No abstract available.

PMID:
17120481
48.

Impact of surgery on the development of duodenal cancer in patients with familial adenomatous polyposis.

Biasco G, Nobili E, Calabrese C, Sassatelli R, Camellini L, Pantaleo MA, Bertoni G, De Vivo A, Ponz De Leon M, Poggioli G, Bedogni G, Venesio T, Varesco L, Risio M, Di Febo G, Brandi G.

Dis Colon Rectum. 2006 Dec;49(12):1860-6.

PMID:
17103055
49.

Immunohistochemical expression of MYH protein can be used to identify patients with MYH-associated polyposis.

Di Gregorio C, Frattini M, Maffei S, Ponti G, Losi L, Pedroni M, Venesio T, Bertario L, Varesco L, Risio M, Ponz de Leon M.

Gastroenterology. 2006 Aug;131(2):439-44.

PMID:
16890597
50.

Adjuvant chemotherapy in colorectal cancer patients with microsatellite instability.

Watanabe T, Kanazawa T, Kazama Y, Tanaka J, Tanaka T, Ishihara S, Nagawa H, Benatti P, Ponz de Leon M, Gafá R, Lanza G, Barana D, Oliani C.

Clin Cancer Res. 2006 Jun 15;12(12):3866-7; author reply 3867. No abstract available.

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