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Items: 39


Urinary miRNA-27b-3p and miRNA-1228-3p correlate with the progression of Kidney Fibrosis in Diabetic Nephropathy.

Conserva F, Barozzino M, Pesce F, Divella C, Oranger A, Papale M, Sallustio F, Simone S, Laviola L, Giorgino F, Gallone A, Pontrelli P, Gesualdo L.

Sci Rep. 2019 Aug 6;9(1):11357. doi: 10.1038/s41598-019-47778-1.


Interleukin-27 is a potential marker for the onset of post-transplant malignancies.

Pontrelli P, Rascio F, Zaza G, Accetturo M, Simone S, Infante B, Furian L, Castellano G, Ditonno P, Battaglia M, Cormio L, Carrieri G, Lupo A, Rigotti P, Gesualdo L, Stallone G, Grandaliano G.

Nephrol Dial Transplant. 2019 Jan 1;34(1):157-166. doi: 10.1093/ndt/gfy206.


Complement Activation During Ischemia/Reperfusion Injury Induces Pericyte-to-Myofibroblast Transdifferentiation Regulating Peritubular Capillary Lumen Reduction Through pERK Signaling.

Castellano G, Franzin R, Stasi A, Divella C, Sallustio F, Pontrelli P, Lucarelli G, Battaglia M, Staffieri F, Crovace A, Stallone G, Seelen M, Daha MR, Grandaliano G, Gesualdo L.

Front Immunol. 2018 May 23;9:1002. doi: 10.3389/fimmu.2018.01002. eCollection 2018.


Deregulation of autophagy under hyperglycemic conditions is dependent on increased lysine 63 ubiquitination: a candidate mechanism in the progression of diabetic nephropathy.

Pontrelli P, Oranger A, Barozzino M, Divella C, Conserva F, Fiore MG, Rossi R, Papale M, Castellano G, Simone S, Laviola L, Giorgino F, Piscitelli D, Gallone A, Gesualdo L.

J Mol Med (Berl). 2018 Jul;96(7):645-659. doi: 10.1007/s00109-018-1656-3. Epub 2018 May 27.


In Vitro Identification of New Transcriptomic and miRNomic Profiles Associated with Pulmonary Fibrosis Induced by High Doses Everolimus: Looking for New Pathogenetic Markers and Therapeutic Targets.

Granata S, Santoro G, Masola V, Tomei P, Sallustio F, Pontrelli P, Accetturo M, Antonucci N, Carrat├╣ P, Lupo A, Zaza G.

Int J Mol Sci. 2018 Apr 20;19(4). pii: E1250. doi: 10.3390/ijms19041250.


The pathological role of the ubiquitination pathway in diabetic nephropathy.

Pontrelli P, Oranger A, Barozzino M, Conserva F, Papale M, Gesualdo L.

Minerva Med. 2018 Feb;109(1):53-67. doi: 10.23736/S0026-4806.17.05419-2. Epub 2017 Oct 3. Review.


Lysine 63 ubiquitination is involved in the progression of tubular damage in diabetic nephropathy.

Pontrelli P, Conserva F, Papale M, Oranger A, Barozzino M, Vocino G, Rocchetti MT, Gigante M, Castellano G, Rossini M, Simone S, Laviola L, Giorgino F, Grandaliano G, Di Paolo S, Gesualdo L.

FASEB J. 2017 Jan;31(1):308-319. doi: 10.1096/fj.201600382RR. Epub 2016 Oct 24.


Establishment and characterization of a highly immunogenic human renal carcinoma cell line.

Prattichizzo C, Gigante M, Pontrelli P, Stella A, Rocchetti MT, Gigante M, Maiorano E, Herr W, Battaglia M, Gesualdo L, Ranieri E.

Int J Oncol. 2016 Aug;49(2):457-70. doi: 10.3892/ijo.2016.3544. Epub 2016 May 27.


miR-29b and miR-198 overexpression in CD8+ T cells of renal cell carcinoma patients down-modulates JAK3 and MCL-1 leading to immune dysfunction.

Gigante M, Pontrelli P, Herr W, Gigante M, D'Avenia M, Zaza G, Cavalcanti E, Accetturo M, Lucarelli G, Carrieri G, Battaglia M, Storkus WJ, Gesualdo L, Ranieri E.

J Transl Med. 2016 Apr 11;14:84. doi: 10.1186/s12967-016-0841-9.


Soluble Serum ╬▒Klotho Is a Potential Predictive Marker of Disease Progression in Clear Cell Renal Cell Carcinoma.

Gigante M, Lucarelli G, Divella C, Netti GS, Pontrelli P, Cafiero C, Grandaliano G, Castellano G, Rutigliano M, Stallone G, Bettocchi C, Ditonno P, Gesualdo L, Battaglia M, Ranieri E.

Medicine (Baltimore). 2015 Nov;94(45):e1917. doi: 10.1097/MD.0000000000001917.


Complement Modulation of Anti-Aging Factor Klotho in Ischemia/Reperfusion Injury and Delayed Graft Function.

Castellano G, Intini A, Stasi A, Divella C, Gigante M, Pontrelli P, Franzin R, Accetturo M, Zito A, Fiorentino M, Montinaro V, Lucarelli G, Ditonno P, Battaglia M, Crovace A, Staffieri F, Oortwijn B, van Amersfoort E, Pertosa G, Grandaliano G, Gesualdo L.

Am J Transplant. 2016 Jan;16(1):325-33. doi: 10.1111/ajt.13415. Epub 2015 Aug 17.


Thrombin may modulate dendritic cell activation in kidney transplant recipients with delayed graft function.

Pontrelli P, Cariello M, Rascio F, Gigante M, Verrienti R, Tataranni T, Castellano G, Divella C, Ranieri E, Stallone G, Gesualdo L, Grandaliano G.

Nephrol Dial Transplant. 2015 Sep;30(9):1480-7. doi: 10.1093/ndt/gfv129. Epub 2015 Jun 7.


A type I interferon signature characterizes chronic antibody-mediated rejection in kidney transplantation.

Rascio F, Pontrelli P, Accetturo M, Oranger A, Gigante M, Castellano G, Gigante M, Zito A, Zaza G, Lupo A, Ranieri E, Stallone G, Gesualdo L, Grandaliano G.

J Pathol. 2015 Sep;237(1):72-84. doi: 10.1002/path.4553. Epub 2015 Jun 4.


Local synthesis of interferon-alpha in lupus nephritis is associated with type I interferons signature and LMP7 induction in renal tubular epithelial cells.

Castellano G, Cafiero C, Divella C, Sallustio F, Gigante M, Pontrelli P, De Palma G, Rossini M, Grandaliano G, Gesualdo L.

Arthritis Res Ther. 2015 Mar 22;17:72. doi: 10.1186/s13075-015-0588-3.


Endothelial dysfunction and renal fibrosis in endotoxemia-induced oliguric kidney injury: possible role of LPS-binding protein.

Castellano G, Stasi A, Intini A, Gigante M, Di Palma AM, Divella C, Netti GS, Prattichizzo C, Pontrelli P, Crovace A, Staffieri F, Fiaccadori E, Brienza N, Grandaliano G, Pertosa G, Gesualdo L.

Crit Care. 2014 Sep 27;18(5):520. doi: 10.1186/s13054-014-0520-2.


miRNome analysis using real-time PCR.

Pontrelli P, Accetturo M, Gesualdo L.

Methods Mol Biol. 2014;1186:201-32. doi: 10.1007/978-1-4939-1158-5_11.


The microarray-based approach for the analysis of the transcriptome.

Accetturo M, Pontrelli P, Gesualdo L.

Methods Mol Biol. 2014;1186:131-99. doi: 10.1007/978-1-4939-1158-5_10.


Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients.

Zaza G, Rascio F, Pontrelli P, Granata S, Stifanelli P, Accetturo M, Ancona N, Gesualdo L, Lupo A, Grandaliano G.

BMC Med Genomics. 2014 Mar 14;7:14. doi: 10.1186/1755-8794-7-14.


Dialysis-related transcriptomic profiling: the pivotal role of heparanase.

Zaza G, Masola V, Granata S, Pontrelli P, Sallustio F, Gesualdo L, Gambaro G, Grandaliano G, Lupo A.

Exp Biol Med (Maywood). 2014 Jan;239(1):52-64. doi: 10.1177/1535370213506678. Epub 2013 Nov 4.


Rapamycin induces ILT3(high)ILT4(high) dendritic cells promoting a new immunoregulatory pathway.

Stallone G, Pontrelli P, Infante B, Gigante M, Netti GS, Ranieri E, Grandaliano G, Gesualdo L.

Kidney Int. 2014 Apr;85(4):888-97. doi: 10.1038/ki.2013.337. Epub 2013 Oct 9.


A specific immune transcriptomic profile discriminates chronic kidney disease patients in predialysis from hemodialyzed patients.

Zaza G, Granata S, Rascio F, Pontrelli P, Dell'Oglio MP, Cox SN, Pertosa G, Grandaliano G, Lupo A.

BMC Med Genomics. 2013 May 10;6:17. doi: 10.1186/1755-8794-6-17.


The pathogenesis of diabetic nephropathy: focus on microRNAs and proteomics.

Conserva F, Pontrelli P, Accetturo M, Gesualdo L.

J Nephrol. 2013 Sep-Oct;26(5):811-20. doi: 10.5301/jn.5000262. Epub 2013 Mar 27. Review.


Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay.

Fiorentino L, Cavalera M, Menini S, Marchetti V, Mavilio M, Fabrizi M, Conserva F, Casagrande V, Menghini R, Pontrelli P, Arisi I, D'Onofrio M, Lauro D, Khokha R, Accili D, Pugliese G, Gesualdo L, Lauro R, Federici M.

EMBO Mol Med. 2013 Mar;5(3):441-55. doi: 10.1002/emmm.201201475. Epub 2013 Feb 12.


Sirolimus and proteinuria in renal transplant patients: evidence for a dose-dependent effect on slit diaphragm-associated proteins.

Stallone G, Infante B, Pontrelli P, Gigante M, Montemurno E, Loverre A, Rossini M, Schena FP, Grandaliano G, Gesualdo L.

Transplantation. 2011 May 15;91(9):997-1004. doi: 10.1097/TP.0b013e318211d342.


The anti-fibrotic effect of mycophenolic acid-induced neutral endopeptidase.

Dell'Oglio MP, Zaza G, Rossini M, Divella C, Pontrelli P, Verrienti R, Rutigliano M, Ditonno P, Stifanelli P, Ancona N, Schena FP, Grandaliano G.

J Am Soc Nephrol. 2010 Dec;21(12):2157-68. doi: 10.1681/ASN.2010020181. Epub 2010 Sep 23.


Altered modulation of WNT-beta-catenin and PI3K/Akt pathways in IgA nephropathy.

Cox SN, Sallustio F, Serino G, Pontrelli P, Verrienti R, Pesce F, Torres DD, Ancona N, Stifanelli P, Zaza G, Schena FP.

Kidney Int. 2010 Aug;78(4):396-407. doi: 10.1038/ki.2010.138. Epub 2010 May 19.


Mitochondrial dysregulation and oxidative stress in patients with chronic kidney disease.

Granata S, Zaza G, Simone S, Villani G, Latorre D, Pontrelli P, Carella M, Schena FP, Grandaliano G, Pertosa G.

BMC Genomics. 2009 Aug 21;10:388. doi: 10.1186/1471-2164-10-388.


ID2-VEGF-related pathways in the pathogenesis of Kaposi's sarcoma: a link disrupted by rapamycin.

Stallone G, Infante B, Pontrelli P, Ranieri E, Loverre A, Schena A, Cormio L, Carrieri G, Schena FP, Grandaliano G, Gesualdo L.

Am J Transplant. 2009 Mar;9(3):558-66. doi: 10.1111/j.1600-6143.2008.02537.x.


CD2AP mutations are associated with sporadic nephrotic syndrome and focal segmental glomerulosclerosis (FSGS).

Gigante M, Pontrelli P, Montemurno E, Roca L, Aucella F, Penza R, Caridi G, Ranieri E, Ghiggeri GM, Gesualdo L.

Nephrol Dial Transplant. 2009 Jun;24(6):1858-64. doi: 10.1093/ndt/gfn712. Epub 2009 Jan 7.


Rapamycin inhibits PAI-1 expression and reduces interstitial fibrosis and glomerulosclerosis in chronic allograft nephropathy.

Pontrelli P, Rossini M, Infante B, Stallone G, Schena A, Loverre A, Ursi M, Verrienti R, Maiorano A, Zaza G, Ranieri E, Gesualdo L, Ditonno P, Bettocchi C, Schena FP, Grandaliano G.

Transplantation. 2008 Jan 15;85(1):125-34. doi: 10.1097/


Dialysis-related systemic microinflammation is associated with specific genomic patterns.

Zaza G, Pontrelli P, Pertosa G, Granata S, Rossini M, Porreca S, Staal FJ, Gesualdo L, Grandaliano G, Schena FP.

Nephrol Dial Transplant. 2008 May;23(5):1673-81. Epub 2007 Nov 29.


The ratio of epidermal growth factor to monocyte chemotactic peptide-1 in the urine predicts renal prognosis in IgA nephropathy.

Torres DD, Rossini M, Manno C, Mattace-Raso F, D'Altri C, Ranieri E, Pontrelli P, Grandaliano G, Gesualdo L, Schena FP.

Kidney Int. 2008 Feb;73(3):327-33. Epub 2007 Oct 17.


Sirolimus interferes with iron homeostasis in renal transplant recipients.

Maiorano A, Stallone G, Schena A, Infante B, Pontrelli P, Schena FP, Grandaliano G.

Transplantation. 2006 Oct 15;82(7):908-12.


CD40L proinflammatory and profibrotic effects on proximal tubular epithelial cells: role of NF-kappaB and lyn.

Pontrelli P, Ursi M, Ranieri E, Capobianco C, Schena FP, Gesualdo L, Grandaliano G.

J Am Soc Nephrol. 2006 Mar;17(3):627-36. Epub 2006 Feb 1.


CD40 ligand increases complement C3 secretion by proximal tubular epithelial cells.

Castellano G, Cappiello V, Fiore N, Pontrelli P, Gesualdo L, Schena FP, Montinaro V.

J Am Soc Nephrol. 2005 Jul;16(7):2003-11. Epub 2005 May 4.


Ischemia-reperfusion induces glomerular and tubular activation of proinflammatory and antiapoptotic pathways: differential modulation by rapamycin.

Loverre A, Ditonno P, Crovace A, Gesualdo L, Ranieri E, Pontrelli P, Stallone G, Infante B, Schena A, Di Paolo S, Capobianco C, Ursi M, Palazzo S, Battaglia M, Selvaggi FP, Schena FP, Grandaliano G.

J Am Soc Nephrol. 2004 Oct;15(10):2675-86.


jun-N-terminal kinase regulates thrombin-induced PAI-1 gene expression in proximal tubular epithelial cells.

Pontrelli P, Ranieri E, Ursi M, Ghosh-Choudhury G, Gesualdo L, Paolo Schena F, Grandaliano G.

Kidney Int. 2004 Jun;65(6):2249-61.


Protease-activated receptor-2 expression in IgA nephropathy: a potential role in the pathogenesis of interstitial fibrosis.

Grandaliano G, Pontrelli P, Cerullo G, Monno R, Ranieri E, Ursi M, Loverre A, Gesualdo L, Schena FP.

J Am Soc Nephrol. 2003 Aug;14(8):2072-83.


Protease-activated receptor 1 and plasminogen activator inhibitor 1 expression in chronic allograft nephropathy: the role of coagulation and fibrinolysis in renal graft fibrosis.

Grandaliano G, Di Paolo S, Monno R, Stallone G, Ranieri E, Pontrelli P, Gesualdo L, Schena FP.

Transplantation. 2001 Oct 27;72(8):1437-43.


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