Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 8

1.

Methoxsalen as an in vitro phenotyping tool in comparison with 1-aminobenzotriazole.

Palacharla RC, Molgara P, Panthangi HR, Boggavarapu RK, Manoharan AK, Ponnamaneni RK, Ajjala DR, Nirogi R.

Xenobiotica. 2018 Feb 15:1-8. doi: 10.1080/00498254.2018.1434913. [Epub ahead of print]

PMID:
29382249
2.

Quantitative in vitro phenotyping and prediction of drug interaction potential of CYP2B6 substrates as victims.

Palacharla RC, Nirogi R, Uthukam V, Manoharan A, Ponnamaneni RK, Kalaikadhiban I.

Xenobiotica. 2018 Jul;48(7):663-675. doi: 10.1080/00498254.2017.1354267. Epub 2017 Jul 28.

PMID:
28737446
3.

Inhibition of cytochrome P450 enzymes by saturated and unsaturated fatty acids in human liver microsomes, characterization of enzyme kinetics in the presence of bovine serum albumin (0.1 and 1.0% w/v) and in vitro - in vivo extrapolation of hepatic clearance.

Palacharla RC, Uthukam V, Manoharan A, Ponnamaneni RK, Padala NP, Boggavarapu RK, Bhyrapuneni G, Ajjala DR, Nirogi R.

Eur J Pharm Sci. 2017 Apr 1;101:80-89. doi: 10.1016/j.ejps.2017.01.027. Epub 2017 Feb 4.

PMID:
28179134
4.

Evaluation of metabolism dependent inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators of drug interaction.

Nirogi R, Palacharla RC, Mohammed AR, Manoharan A, Ponnamaneni RK, Bhyrapuneni G.

Chem Biol Interact. 2015 Mar 25;230:9-20. doi: 10.1016/j.cbi.2015.01.028. Epub 2015 Feb 3.

PMID:
25656918
5.

Chemical inhibitors of CYP450 enzymes in liver microsomes: combining selectivity and unbound fractions to guide selection of appropriate concentration in phenotyping assays.

Nirogi R, Palacharla RC, Uthukam V, Manoharan A, Srikakolapu SR, Kalaikadhiban I, Boggavarapu RK, Ponnamaneni RK, Ajjala DR, Bhyrapuneni G.

Xenobiotica. 2015 Feb;45(2):95-106. doi: 10.3109/00498254.2014.945196. Epub 2014 Jul 29.

PMID:
25070627
6.

Identification of a suitable and selective inhibitor towards aldehyde oxidase catalyzed reactions.

Nirogi R, Kandikere V, Palacharla RC, Bhyrapuneni G, Kanamarlapudi VB, Ponnamaneni RK, Manoharan AK.

Xenobiotica. 2014 Mar;44(3):197-204. doi: 10.3109/00498254.2013.819594. Epub 2013 Oct 24.

PMID:
24156774
7.

In vivo receptor occupancy assay of histamine H₃ receptor antagonist in rats using non-radiolabeled tracer.

Nirogi R, Kandikere V, Bhyrapuneni G, Muddana N, Saralaya R, Ponnamaneni RK, Manoharan AK.

J Pharmacol Toxicol Methods. 2012 May-Jun;65(3):115-21. doi: 10.1016/j.vascn.2012.03.003. Epub 2012 Apr 1.

PMID:
22487318
8.

Effect of dimethyl sulfoxide on in vitro cytochrome P4501A2 mediated phenacetin O-deethylation in human liver microsomes.

Nirogi R, Kandikere V, Bhyrapuneni G, Ponnamaneni RK, Palacharla Rc, Manoharan A.

Drug Metab Dispos. 2011 Nov;39(11):2162-4. doi: 10.1124/dmd.111.041160. Epub 2011 Aug 8.

Supplemental Content

Loading ...
Support Center