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Items: 38

1.

Synthesis and biological evaluation of novel tamoxifen analogues.

Christodoulou MS, Fokialakis N, Passarella D, García-Argáez AN, Gia OM, Pongratz I, Dalla Via L, Haroutounian SA.

Bioorg Med Chem. 2013 Jul 15;21(14):4120-31. doi: 10.1016/j.bmc.2013.05.012. Epub 2013 May 15.

PMID:
23735829
2.

Tryptamine serves as a proligand of the AhR transcriptional pathway whose activation is dependent of monoamine oxidases.

Vikström Bergander L, Cai W, Klocke B, Seifert M, Pongratz I.

Mol Endocrinol. 2012 Sep;26(9):1542-51. doi: 10.1210/me.2011-1351. Epub 2012 Aug 3.

3.

The aryl hydrocarbon receptor ligands 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene regulate distinct genetic networks.

Swedenborg E, Kotka M, Seifert M, Kanno J, Pongratz I, Rüegg J.

Mol Cell Endocrinol. 2012 Oct 15;362(1-2):39-47. doi: 10.1016/j.mce.2012.05.006. Epub 2012 May 24.

PMID:
22634562
4.

Epigenetic regulation of glucose transporter 4 by estrogen receptor β.

Rüegg J, Cai W, Karimi M, Kiss NB, Swedenborg E, Larsson C, Ekström TJ, Pongratz I.

Mol Endocrinol. 2011 Dec;25(12):2017-28. doi: 10.1210/me.2011-1054. Epub 2011 Oct 20.

5.

The immunophilin-like protein XAP2 is a negative regulator of estrogen signaling through interaction with estrogen receptor α.

Cai W, Kramarova TV, Berg P, Korbonits M, Pongratz I.

PLoS One. 2011;6(10):e25201. doi: 10.1371/journal.pone.0025201. Epub 2011 Oct 3.

6.

A single dose of enterolactone activates estrogen signaling and regulates expression of circadian clock genes in mice.

Damdimopoulou P, Nurmi T, Salminen A, Damdimopoulos AE, Kotka M, van der Saag P, Strauss L, Poutanen M, Pongratz I, Mäkelä S.

J Nutr. 2011 Sep;141(9):1583-9. doi: 10.3945/jn.111.140277. Epub 2011 Jul 13.

PMID:
21753063
7.

Endocrine disruptors targeting ERbeta function.

Swedenborg E, Pongratz I, Gustafsson JA.

Int J Androl. 2010 Apr;33(2):288-97. doi: 10.1111/j.1365-2605.2009.01025.x. Epub 2009 Dec 30. Review.

PMID:
20050941
8.

AhR and ARNT modulate ER signaling.

Swedenborg E, Pongratz I.

Toxicology. 2010 Feb 9;268(3):132-8. doi: 10.1016/j.tox.2009.09.007. Epub 2009 Sep 22. Review.

PMID:
19778576
9.

Regulation of estrogen receptor beta activity and implications in health and disease.

Swedenborg E, Power KA, Cai W, Pongratz I, Rüegg J.

Cell Mol Life Sci. 2009 Dec;66(24):3873-94. doi: 10.1007/s00018-009-0118-z. Review.

PMID:
19669093
10.

A CASCADE of effects of bisphenol A.

Bondesson M, Jönsson J, Pongratz I, Olea N, Cravedi JP, Zalko D, Håkansson H, Halldin K, Di Lorenzo D, Behl C, Manthey D, Balaguer P, Demeneix B, Fini JB, Laudet V, Gustafsson JA.

Reprod Toxicol. 2009 Dec;28(4):563-7. doi: 10.1016/j.reprotox.2009.06.014. Epub 2009 Jul 3. No abstract available.

PMID:
19577634
11.

The endogenous retinoid metabolite S-4-oxo-9-cis-13,14-dihydro-retinoic acid activates retinoic acid receptor signalling both in vitro and in vivo.

Schuchardt JP, Wahlström D, Rüegg J, Giese N, Stefan M, Hopf H, Pongratz I, Håkansson H, Eichele G, Pettersson K, Nau H.

FEBS J. 2009 Jun;276(11):3043-59. doi: 10.1111/j.1742-4658.2009.07023.x. Epub 2009 Apr 22.

12.

Endocrine disruptive chemicals: mechanisms of action and involvement in metabolic disorders.

Swedenborg E, Rüegg J, Mäkelä S, Pongratz I.

J Mol Endocrinol. 2009 Jul;43(1):1-10. doi: 10.1677/JME-08-0132. Epub 2009 Feb 11. Review.

PMID:
19211731
13.

Receptors mediating toxicity and their involvement in endocrine disruption.

Rüegg J, Penttinen-Damdimopoulou P, Mäkelä S, Pongratz I, Gustafsson JA.

EXS. 2009;99:289-323. Review.

PMID:
19157066
14.

An amphioxus orthologue of the estrogen receptor that does not bind estradiol: insights into estrogen receptor evolution.

Paris M, Pettersson K, Schubert M, Bertrand S, Pongratz I, Escriva H, Laudet V.

BMC Evol Biol. 2008 Jul 25;8:219. doi: 10.1186/1471-2148-8-219.

15.

Biotransformation of genistein and bisphenol A in cell lines used for screening endocrine disruptors.

Bursztyka J, Perdu E, Pettersson K, Pongratz I, Fernández-Cabrera M, Olea N, Debrauwer L, Zalko D, Cravedi JP.

Toxicol In Vitro. 2008 Sep;22(6):1595-604. doi: 10.1016/j.tiv.2008.06.013. Epub 2008 Jul 2.

PMID:
18640261
16.

Expression levels of estrogen receptor beta are modulated by components of the molecular clock.

Cai W, Rambaud J, Teboul M, Masse I, Benoit G, Gustafsson JA, Delaunay F, Laudet V, Pongratz I.

Mol Cell Biol. 2008 Jan;28(2):784-93. Epub 2007 Nov 26.

17.

3-Methylcholanthrene displays dual effects on estrogen receptor (ER) alpha and ER beta signaling in a cell-type specific fashion.

Swedenborg E, Rüegg J, Hillenweck A, Rehnmark S, Faulds MH, Zalko D, Pongratz I, Pettersson K.

Mol Pharmacol. 2008 Feb;73(2):575-86. Epub 2007 Nov 14.

PMID:
18003862
18.
19.

Diet-derived polyphenol metabolite enterolactone is a tissue-specific estrogen receptor activator.

Penttinen P, Jaehrling J, Damdimopoulos AE, Inzunza J, Lemmen JG, van der Saag P, Pettersson K, Gauglitz G, Mäkelä S, Pongratz I.

Endocrinology. 2007 Oct;148(10):4875-86. Epub 2007 Jul 12.

PMID:
17628008
20.

The co-chaperone XAP2 is required for activation of hypothalamic thyrotropin-releasing hormone transcription in vivo.

Froidevaux MS, Berg P, Seugnet I, Decherf S, Becker N, Sachs LM, Bilesimo P, Nygård M, Pongratz I, Demeneix BA.

EMBO Rep. 2006 Oct;7(10):1035-9. Epub 2006 Aug 25. Erratum in: EMBO Rep. 2006 Nov;7(11):1182.

21.

The basic helix-loop-helix-PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcription.

Brunnberg S, Pettersson K, Rydin E, Matthews J, Hanberg A, Pongratz I.

Proc Natl Acad Sci U S A. 2003 May 27;100(11):6517-22. Epub 2003 May 16.

22.

Mammalian two-hybrid assay showing redox control of HIF-like factor.

Lando D, Peet DJ, Pongratz I, Whitelaw ML.

Methods Enzymol. 2002;353:3-10. No abstract available.

PMID:
12078504
23.

Two parallel pathways mediate cytoplasmic localization of the dioxin (aryl hydrocarbon) receptor.

Berg P, Pongratz I.

J Biol Chem. 2002 Aug 30;277(35):32310-9. Epub 2002 Jun 13.

24.

Two distinct regions of the immunophilin-like protein XAP2 regulate dioxin receptor function and interaction with hsp90.

Kazlauskas A, Poellinger L, Pongratz I.

J Biol Chem. 2002 Apr 5;277(14):11795-801. Epub 2002 Jan 22.

25.
26.

The hsp90 chaperone complex regulates intracellular localization of the dioxin receptor.

Kazlauskas A, Sundström S, Poellinger L, Pongratz I.

Mol Cell Biol. 2001 Apr;21(7):2594-607.

27.

The immunophilin-like protein XAP2 regulates ubiquitination and subcellular localization of the dioxin receptor.

Kazlauskas A, Poellinger L, Pongratz I.

J Biol Chem. 2000 Dec 29;275(52):41317-24.

28.
29.

Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (Aryl hydrocarbon) receptor.

Kazlauskas A, Poellinger L, Pongratz I.

J Biol Chem. 1999 May 7;274(19):13519-24.

30.

Role of the PAS domain in regulation of dimerization and DNA binding specificity of the dioxin receptor.

Pongratz I, Antonsson C, Whitelaw ML, Poellinger L.

Mol Cell Biol. 1998 Jul;18(7):4079-88.

31.

Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor.

Kallio PJ, Pongratz I, Gradin K, McGuire J, Poellinger L.

Proc Natl Acad Sci U S A. 1997 May 27;94(11):5667-72.

32.

A cellular factor stimulates ligand-dependent release of hsp90 from the basic helix-loop-helix dioxin receptor.

McGuire J, Whitelaw ML, Pongratz I, Gustafsson JA, Poellinger L.

Mol Cell Biol. 1994 Apr;14(4):2438-46.

33.

Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor.

Whitelaw M, Pongratz I, Wilhelmsson A, Gustafsson JA, Poellinger L.

Mol Cell Biol. 1993 Apr;13(4):2504-14.

34.
36.

Inhibition of the specific DNA binding activity of the dioxin receptor by phosphatase treatment.

Pongratz I, Strömstedt PE, Mason GG, Poellinger L.

J Biol Chem. 1991 Sep 5;266(25):16813-7.

37.
38.

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