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Items: 26

1.

Adverse pharmacokinetic interactions between illicit substances and clinical drugs.

Abbott KL, Flannery PC, Gill KS, Boothe DM, Dhanasekaran M, Mani S, Pondugula SR.

Drug Metab Rev. 2019 Dec 11:1-22. doi: 10.1080/03602532.2019.1697283. [Epub ahead of print]

PMID:
31826670
2.

Correlation of PPM1A Downregulation with CYP3A4 Repression in the Tumor Liver Tissue of Hepatocellular Carcinoma Patients.

Flannery PC, Abbott KL, Pondugula SR.

Eur J Drug Metab Pharmacokinet. 2019 Dec 2. doi: 10.1007/s13318-019-00595-3. [Epub ahead of print]

PMID:
31792727
3.

Screening for CYP3A4 inhibition and induction coupled to parallel artificial membrane permeability assay (PAMPA) for prediction of botanical-drug interactions: The case of açaí and maca.

Zhang Y, Rants'o TA, Jung D, Lopez E, Abbott K, Pondugula SR, McLendon L, Qian J, Hansen RA, Calderón AI.

Phytomedicine. 2019 Jun;59:152915. doi: 10.1016/j.phymed.2019.152915. Epub 2019 Apr 3.

PMID:
30981185
4.

Belinostat, at Its Clinically Relevant Concentrations, Inhibits Rifampicin-Induced CYP3A4 and MDR1 Gene Expression.

Abbott KL, Chaudhury CS, Chandran A, Vishveshwara S, Dvorak Z, Jiskrova E, Poulikova K, Vyhlidalova B, Mani S, Pondugula SR.

Mol Pharmacol. 2019 Mar;95(3):324-334. doi: 10.1124/mol.118.114587. Epub 2019 Jan 8.

PMID:
30622215
5.

The Combination of Omega-3 Stearidonic Acid and Docetaxel Enhances Cell Death over Docetaxel Alone in Human Prostate Cancer Cells.

Mansour M, van Ginkel S, Dennis JC, Mason B, Elhussin I, Abbott K, Pondugula SR, Samuel T, Morrison E.

J Cancer. 2018 Nov 11;9(23):4536-4546. doi: 10.7150/jca.26681. eCollection 2018.

6.

Pregnane X Receptor and Cancer: Context-Specificity is Key.

Pondugula SR, Pavek P, Mani S.

Nucl Receptor Res. 2016 Jun 12;3. pii: 101198.

7.

Pyrimido[1″,2″:1,5]pyrazolo[3,4-b]quinolines: Novel compounds that reverse ABCG2-mediated resistance in cancer cells.

Karthikeyan C, Malla R, Ashby CR Jr, Amawi H, Abbott KL, Moore J, Chen J, Balch C, Lee C, Flannery PC, Trivedi P, Faridi JS, Pondugula SR, Tiwari AK.

Cancer Lett. 2016 Jun 28;376(1):118-26. doi: 10.1016/j.canlet.2016.03.030. Epub 2016 Mar 21.

PMID:
27012188
8.

Serine 350 of human pregnane X receptor is crucial for its heterodimerization with retinoid X receptor alpha and transactivation of target genes in vitro and in vivo.

Wang YM, Chai SC, Lin W, Chai X, Elias A, Wu J, Ong SS, Pondugula SR, Beard JA, Schuetz EG, Zeng S, Xie W, Chen T.

Biochem Pharmacol. 2015 Aug 15;96(4):357-68. doi: 10.1016/j.bcp.2015.06.018. Epub 2015 Jun 25.

9.

3-(2-Bromoethyl)-indole inhibits the growth of cancer cells and NF-κB activation.

Fadlalla K, Elgendy R, Gilbreath E, Pondugula SR, Yehualaeshet T, Mansour M, Serbessa T, Manne U, Samuel T.

Oncol Rep. 2015 Jul;34(1):495-503. doi: 10.3892/or.2015.3970. Epub 2015 May 11.

10.

Stearidonic acid, a plant-based dietary fatty acid, enhances the chemosensitivity of canine lymphoid tumor cells.

Pondugula SR, Ferniany G, Ashraf F, Abbott KL, Smith BF, Coleman ES, Mansour M, Bird RC, Smith AN, Karthikeyan C, Trivedi P, Tiwari AK.

Biochem Biophys Res Commun. 2015 May 15;460(4):1002-7. doi: 10.1016/j.bbrc.2015.03.141. Epub 2015 Apr 4.

PMID:
25847597
11.

Mg2+/Mn2+-dependent phosphatase 1A is involved in regulating pregnane X receptor-mediated cytochrome p450 3A4 gene expression.

Pondugula SR, Flannery PC, Apte U, Babu JR, Geetha T, Rege SD, Chen T, Abbott KL.

Drug Metab Dispos. 2015 Mar;43(3):385-91. doi: 10.1124/dmd.114.062083. Epub 2015 Jan 5.

PMID:
25561723
12.

Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR.

Pondugula SR, Flannery PC, Abbott KL, Coleman ES, Mani S, Samuel T, Xie W.

Toxicol Lett. 2015 Feb 3;232(3):580-9. doi: 10.1016/j.toxlet.2014.12.015. Epub 2014 Dec 24.

13.

IND-2, a pyrimido[1″,2″:1,5]pyrazolo[3,4-b]quinoline derivative, circumvents multi-drug resistance and causes apoptosis in colon cancer cells.

Karthikeyan C, Lee C, Moore J, Mittal R, Suswam EA, Abbott KL, Pondugula SR, Manne U, Narayanan NK, Trivedi P, Tiwari AK.

Bioorg Med Chem. 2015 Feb 1;23(3):602-11. doi: 10.1016/j.bmc.2014.11.043. Epub 2014 Dec 8.

14.

Noncoding RNAs in Neurodegenerative Diseases.

Rege SD, Geetha T, Pondugula SR, Zizza CA, Wernette CM, Babu JR.

ISRN Neurol. 2013 Apr 30;2013:375852. doi: 10.1155/2013/375852. Print 2013.

15.

cAMP-stimulated Cl- secretion is increased by glucocorticoids and inhibited by bumetanide in semicircular canal duct epithelium.

Pondugula SR, Kampalli SB, Wu T, De Lisle RC, Raveendran NN, Harbidge DG, Marcus DC.

BMC Physiol. 2013 Mar 27;13:6. doi: 10.1186/1472-6793-13-6.

16.

Pregnane xenobiotic receptor in cancer pathogenesis and therapeutic response.

Pondugula SR, Mani S.

Cancer Lett. 2013 Jan 1;328(1):1-9. doi: 10.1016/j.canlet.2012.08.030. Epub 2012 Aug 29. Review.

17.

Sodium selectivity of semicircular canal duct epithelial cells.

Yamazaki M, Wu T, Pondugula SR, Harbidge DG, Marcus DC.

BMC Res Notes. 2011 Sep 13;4:355. doi: 10.1186/1756-0500-4-355.

18.

Protein phosphatase 2Cbetal regulates human pregnane X receptor-mediated CYP3A4 gene expression in HepG2 liver carcinoma cells.

Pondugula SR, Tong AA, Wu J, Cui J, Chen T.

Drug Metab Dispos. 2010 Sep;38(9):1411-6. doi: 10.1124/dmd.110.032128. Epub 2010 Jun 10.

19.

Ion transport regulation by P2Y receptors, protein kinase C and phosphatidylinositol 3-kinase within the semicircular canal duct epithelium.

Pondugula SR, Raveendran NN, Marcus DC.

BMC Res Notes. 2010 Apr 14;3:100. doi: 10.1186/1756-0500-3-100.

20.

Phosphorylation and protein-protein interactions in PXR-mediated CYP3A repression.

Pondugula SR, Dong H, Chen T.

Expert Opin Drug Metab Toxicol. 2009 Aug;5(8):861-73. doi: 10.1517/17425250903012360. Review.

21.

A phosphomimetic mutation at threonine-57 abolishes transactivation activity and alters nuclear localization pattern of human pregnane x receptor.

Pondugula SR, Brimer-Cline C, Wu J, Schuetz EG, Tyagi RK, Chen T.

Drug Metab Dispos. 2009 Apr;37(4):719-30. doi: 10.1124/dmd.108.024695. Epub 2009 Jan 26.

22.

Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epithelium.

Kim SH, Kim KX, Raveendran NN, Wu T, Pondugula SR, Marcus DC.

Am J Physiol Cell Physiol. 2009 Mar;296(3):C544-57. doi: 10.1152/ajpcell.00338.2008. Epub 2009 Jan 14.

23.

Glucocorticoid regulation of genes in the amiloride-sensitive sodium transport pathway by semicircular canal duct epithelium of neonatal rat.

Pondugula SR, Raveendran NN, Ergonul Z, Deng Y, Chen J, Sanneman JD, Palmer LG, Marcus DC.

Physiol Genomics. 2006 Jan 12;24(2):114-23. Epub 2005 Nov 1.

PMID:
16263802
24.

Vitamin D upregulates expression of ECaC1 mRNA in semicircular canal.

Yamauchi D, Raveendran NN, Pondugula SR, Kampalli SB, Sanneman JD, Harbidge DG, Marcus DC.

Biochem Biophys Res Commun. 2005 Jun 17;331(4):1353-7.

PMID:
15883024
25.

Glucocorticoids stimulate cation absorption by semicircular canal duct epithelium via epithelial sodium channel.

Pondugula SR, Sanneman JD, Wangemann P, Milhaud PG, Marcus DC.

Am J Physiol Renal Physiol. 2004 Jun;286(6):F1127-35. Epub 2004 Mar 2.

26.

Chloride secretion by semicircular canal duct epithelium is stimulated via beta 2-adrenergic receptors.

Milhaud PG, Pondugula SR, Lee JH, Herzog M, Lehouelleur J, Wangemann P, Sans A, Marcus DC.

Am J Physiol Cell Physiol. 2002 Dec;283(6):C1752-60. Epub 2002 Aug 28.

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