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microRNA-146a-5p association with the cardiometabolic disease risk factor TMAO.

Coffey AR, Kanke M, Smallwood TL, Albright J, Pitman W, Gharaibeh RZ, Hua K, Gertz E, Biddinger SB, Temel RE, Pomp D, Sethupathy P, Bennett BJ.

Physiol Genomics. 2019 Feb 1;51(2):59-71. doi: 10.1152/physiolgenomics.00079.2018. Epub 2019 Jan 11.


Correction to: Quantitative trait mapping in Diversity Outbred mice identifies two genomic regions associated with heart size.

Shorter JR, Huang W, Beak JY, Hua K, Gatti DM, de Villena FP, Pomp D, Jensen BC.

Mamm Genome. 2018 Dec 4. doi: 10.1007/s00335-018-9789-9. [Epub ahead of print]


CC002/Unc females are mouse models of exercise-induced paradoxical fat response.

McMullan RC, Ferris MT, Bell TA, Menachery VD, Baric RS, Hua K, Pomp D, Smith-Ryan AE, de Villena FP.

Physiol Rep. 2018 Jun;6(12):e13716. doi: 10.14814/phy2.13716.


Developmental constraint through negative pleiotropy in the zygomatic arch.

Percival CJ, Green R, Roseman CC, Gatti DM, Morgan JL, Murray SA, Donahue LR, Mayeux JM, Pollard KM, Hua K, Pomp D, Marcucio R, Hallgrímsson B.

Evodevo. 2018 Jan 27;9:3. doi: 10.1186/s13227-018-0092-3. eCollection 2018.


Quantitative trait mapping in Diversity Outbred mice identifies two genomic regions associated with heart size.

Shorter JR, Huang W, Beak JY, Hua K, Gatti DM, de Villena FP, Pomp D, Jensen BC.

Mamm Genome. 2018 Feb;29(1-2):80-89. doi: 10.1007/s00335-017-9730-7. Epub 2017 Dec 26. Erratum in: Mamm Genome. 2018 Dec 4;:.


Biological/Genetic Regulation of Physical Activity Level: Consensus from GenBioPAC.

Lightfoot JT, DE Geus EJC, Booth FW, Bray MS, DEN Hoed M, Kaprio J, Kelly SA, Pomp D, Saul MC, Thomis MA, Garland T Jr, Bouchard C.

Med Sci Sports Exerc. 2018 Apr;50(4):863-873. doi: 10.1249/MSS.0000000000001499. Review.


Improving Metabolic Health Through Precision Dietetics in Mice.

Barrington WT, Wulfridge P, Wells AE, Rojas CM, Howe SYF, Perry A, Hua K, Pellizzon MA, Hansen KD, Voy BH, Bennett BJ, Pomp D, Feinberg AP, Threadgill DW.

Genetics. 2018 Jan;208(1):399-417. doi: 10.1534/genetics.117.300536. Epub 2017 Nov 20.


Systems genetics identifies a co-regulated module of liver microRNAs associated with plasma LDL cholesterol in murine diet-induced dyslipidemia.

Coffey AR, Smallwood TL, Albright J, Hua K, Kanke M, Pomp D, Bennett BJ, Sethupathy P.

Physiol Genomics. 2017 Nov 1;49(11):618-629. doi: 10.1152/physiolgenomics.00050.2017. Epub 2017 Sep 15.


Aerobic exercise prevents rarefaction of pial collaterals and increased stroke severity that occur with aging.

Rzechorzek W, Zhang H, Buckley BK, Hua K, Pomp D, Faber JE.

J Cereb Blood Flow Metab. 2017 Nov;37(11):3544-3555. doi: 10.1177/0271678X17718966. Epub 2017 Jul 7.


Prevention of tumorigenesis in mice by exercise is dependent on strain background and timing relative to carcinogen exposure.

Kelly SA, Zhao L, Jung KC, Hua K, Threadgill DW, Kim Y, de Villena FP, Pomp D.

Sci Rep. 2017 Feb 22;7:43086. doi: 10.1038/srep43086.


Long-term exercise in mice has sex-dependent benefits on body composition and metabolism during aging.

McMullan RC, Kelly SA, Hua K, Buckley BK, Faber JE, Pardo-Manuel de Villena F, Pomp D.

Physiol Rep. 2016 Nov;4(21). pii: e13011. Epub 2016 Nov 14.


R2d2 Drives Selfish Sweeps in the House Mouse.

Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, French JE, Gabriel SI, Gatti DM, Garland T Jr, Giagia-Athanasopoulou EB, Giménez MD, Grize SA, Gündüz İ, Holmes A, Hauffe HC, Herman JS, Holt JM, Hua K, Jolley WJ, Lindholm AK, López-Fuster MJ, Mitsainas G, da Luz Mathias M, McMillan L, Ramalhinho Mda G, Rehermann B, Rosshart SP, Searle JB, Shiao MS, Solano E, Svenson KL, Thomas-Laemont P, Threadgill DW, Ventura J, Weinstock GM, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

Mol Biol Evol. 2016 Jun;33(6):1381-95. doi: 10.1093/molbev/msw036. Epub 2016 Feb 15.


Decomposing genomic variance using information from GWA, GWE and eQTL analysis.

Ehsani A, Janss L, Pomp D, Sørensen P.

Anim Genet. 2016 Apr;47(2):165-73. doi: 10.1111/age.12396. Epub 2015 Dec 17.


The 'Omics' of Voluntary Exercise: Systems Approaches to a Complex Phenotype.

Kelly SA, Villena FP, Pomp D.

Trends Endocrinol Metab. 2015 Dec;26(12):673-675. doi: 10.1016/j.tem.2015.10.002. Epub 2015 Nov 6.


Maternal exercise before and during pregnancy does not impact offspring exercise or body composition in mice.

Kelly SA, Hua K, Wallace JN, Wells SE, Nehrenberg DL, Pomp D.

J Negat Results Biomed. 2015 Aug 3;14:13. doi: 10.1186/s12952-015-0032-x.


A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, Geiger TR, Gooch TJ, Garland T Jr, Harrill AH, Hunter K, McMillan L, Holt M, Miller DR, O'Brien DA, Paigen K, Pan W, Rowe LB, Shaw GD, Simecek P, Sullivan PF, Svenson KL, Weinstock GM, Threadgill DW, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

PLoS Genet. 2015 Feb 13;11(2):e1004850. doi: 10.1371/journal.pgen.1004850. eCollection 2015 Feb.


Host genetics and diet, but not immunoglobulin A expression, converge to shape compositional features of the gut microbiome in an advanced intercross population of mice.

Leamy LJ, Kelly SA, Nietfeldt J, Legge RM, Ma F, Hua K, Sinha R, Peterson DA, Walter J, Benson AK, Pomp D.

Genome Biol. 2014;15(12):552.


High-resolution genetic mapping in the diversity outbred mouse population identifies Apobec1 as a candidate gene for atherosclerosis.

Smallwood TL, Gatti DM, Quizon P, Weinstock GM, Jung KC, Zhao L, Hua K, Pomp D, Bennett BJ.

G3 (Bethesda). 2014 Oct 23;4(12):2353-63. doi: 10.1534/g3.114.014704.


Quantitative trait locus mapping methods for diversity outbred mice.

Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA.

G3 (Bethesda). 2014 Sep 18;4(9):1623-33. doi: 10.1534/g3.114.013748.


Quantitative genomics of voluntary exercise in mice: transcriptional analysis and mapping of expression QTL in muscle.

Kelly SA, Nehrenberg DL, Hua K, Garland T Jr, Pomp D.

Physiol Genomics. 2014 Aug 15;46(16):593-601. doi: 10.1152/physiolgenomics.00023.2014. Epub 2014 Jun 17.


Quantitative trait loci for energy balance traits in an advanced intercross line derived from mice divergently selected for heat loss.

Leamy LJ, Elo K, Nielsen MK, Thorn SR, Valdar W, Pomp D.

PeerJ. 2014 May 27;2:e392. doi: 10.7717/peerj.392. eCollection 2014.


A novel intronic single nucleotide polymorphism in the myosin heavy polypeptide 4 gene is responsible for the mini-muscle phenotype characterized by major reduction in hind-limb muscle mass in mice.

Kelly SA, Bell TA, Selitsky SR, Buus RJ, Hua K, Weinstock GM, Garland T Jr, Pardo-Manuel de Villena F, Pomp D.

Genetics. 2013 Dec;195(4):1385-95. doi: 10.1534/genetics.113.154476. Epub 2013 Sep 20.


Quantitative trait loci for bone mineral density and femoral morphology in an advanced intercross population of mice.

Leamy LJ, Kelly SA, Hua K, Farber CR, Pomp D.

Bone. 2013 Jul;55(1):222-9. doi: 10.1016/j.bone.2013.02.014. Epub 2013 Feb 26.


Genetic determinants of voluntary exercise.

Kelly SA, Pomp D.

Trends Genet. 2013 Jun;29(6):348-57. doi: 10.1016/j.tig.2012.12.007. Epub 2013 Jan 23. Review.


Exercise and diet affect quantitative trait loci for body weight and composition traits in an advanced intercross population of mice.

Leamy LJ, Kelly SA, Hua K, Pomp D.

Physiol Genomics. 2012 Dec 1;44(23):1141-53. doi: 10.1152/physiolgenomics.00115.2012. Epub 2012 Oct 9.


Inferring genetic architecture of complex traits using Bayesian integrative analysis of genome and transcriptome data.

Ehsani A, Sørensen P, Pomp D, Allan M, Janss L.

BMC Genomics. 2012 Sep 5;13:456. doi: 10.1186/1471-2164-13-456.


Functional genomic architecture of predisposition to voluntary exercise in mice: expression QTL in the brain.

Kelly SA, Nehrenberg DL, Hua K, Garland T Jr, Pomp D.

Genetics. 2012 Jun;191(2):643-54. doi: 10.1534/genetics.112.140509. Epub 2012 Mar 30.


Sex-, diet-, and cancer-dependent epistatic effects on complex traits in mice.

Leamy LJ, Gordon RR, Pomp D.

Front Genet. 2011 Oct 28;2:71. doi: 10.3389/fgene.2011.00071. eCollection 2011.


Advances in comparative genetics: influence of genetics on obesity.

Mathes WF, Kelly SA, Pomp D.

Br J Nutr. 2011 Oct;106 Suppl 1:S1-10. doi: 10.1017/S0007114511001905. Review.


Epistatic interactions of genes influence within-individual variation of physical activity traits in mice.

Leamy LJ, Pomp D, Lightfoot JT.

Genetica. 2011 Jun;139(6):813-21. doi: 10.1007/s10709-011-9586-9. Epub 2011 Jun 11.


Identification of quantitative trait loci influencing skeletal architecture in mice: emergence of Cdh11 as a primary candidate gene regulating femoral morphology.

Farber CR, Kelly SA, Baruch E, Yu D, Hua K, Nehrenberg DL, de Villena FP, Buus RJ, Garland T Jr, Pomp D.

J Bone Miner Res. 2011 Sep;26(9):2174-83. doi: 10.1002/jbmr.436.


Architecture of energy balance traits in emerging lines of the Collaborative Cross.

Mathes WF, Aylor DL, Miller DR, Churchill GA, Chesler EJ, de Villena FP, Threadgill DW, Pomp D.

Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1124-34. doi: 10.1152/ajpendo.00707.2010. Epub 2011 Mar 22.


Genetic analysis of complex traits in the emerging Collaborative Cross.

Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, Powell CL, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu EY, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi FA, Pomp D, Threadgill D, de Villena FP, Churchill GA.

Genome Res. 2011 Aug;21(8):1213-22. doi: 10.1101/gr.111310.110. Epub 2011 Mar 15.


Genomic mapping of social behavior traits in a F2 cross derived from mice selectively bred for high aggression.

Nehrenberg DL, Wang S, Buus RJ, Perkins J, de Villena FP, Pomp D.

BMC Genet. 2010 Dec 31;11:113. doi: 10.1186/1471-2156-11-113.


Exercise, weight loss, and changes in body composition in mice: phenotypic relationships and genetic architecture.

Kelly SA, Nehrenberg DL, Hua K, Garland T Jr, Pomp D.

Physiol Genomics. 2011 Feb 24;43(4):199-212. doi: 10.1152/physiolgenomics.00217.2010. Epub 2010 Dec 14.


Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors.

Benson AK, Kelly SA, Legge R, Ma F, Low SJ, Kim J, Zhang M, Oh PL, Nehrenberg D, Hua K, Kachman SD, Moriyama EN, Walter J, Peterson DA, Pomp D.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18933-8. doi: 10.1073/pnas.1007028107. Epub 2010 Oct 11.


A search for quantitative trait loci controlling within-individual variation of physical activity traits in mice.

Leamy LJ, Pomp D, Lightfoot JT.

BMC Genet. 2010 Sep 21;11:83. doi: 10.1186/1471-2156-11-83.


Strain screen and haplotype association mapping of wheel running in inbred mouse strains.

Lightfoot JT, Leamy L, Pomp D, Turner MJ, Fodor AA, Knab A, Bowen RS, Ferguson D, Moore-Harrison T, Hamilton A.

J Appl Physiol (1985). 2010 Sep;109(3):623-34. doi: 10.1152/japplphysiol.00525.2010. Epub 2010 Jun 10.


Genetic architecture of voluntary exercise in an advanced intercross line of mice.

Kelly SA, Nehrenberg DL, Peirce JL, Hua K, Steffy BM, Wiltshire T, Pardo-Manuel de Villena F, Garland T Jr, Pomp D.

Physiol Genomics. 2010 Jul 7;42(2):190-200. doi: 10.1152/physiolgenomics.00028.2010. Epub 2010 Apr 13.


Dietary fat-dependent transcriptional architecture and copy number alterations associated with modifiers of mammary cancer metastasis.

Gordon RR, La Merrill M, Hunter KW, Sørensen P, Threadgill DW, Pomp D.

Clin Exp Metastasis. 2010 May;27(5):279-93. doi: 10.1007/s10585-010-9326-z. Epub 2010 Mar 31.


Mapping interacting QTL for count phenotypes using hierarchical Poisson and binomial models: an application to reproductive traits in mice.

Li J, Reynolds R, Pomp D, Allison DB, Yi N.

Genet Res (Camb). 2010 Feb;92(1):13-23. doi: 10.1017/S0016672310000029. Epub 2010 Mar 4.


The use of plasmodes as a supplement to simulations: A simple example evaluating individual admixture estimation methodologies.

Vaughan LK, Divers J, Padilla M, Redden DT, Tiwari HK, Pomp D, Allison DB.

Comput Stat Data Anal. 2009 Mar 15;53(5):1755-1766.


Dopaminergic dysregulation in mice selectively bred for excessive exercise or obesity.

Mathes WF, Nehrenberg DL, Gordon R, Hua K, Garland T Jr, Pomp D.

Behav Brain Res. 2010 Jul 11;210(2):155-63. doi: 10.1016/j.bbr.2010.02.016. Epub 2010 Feb 13.


Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression.

La Merrill M, Gordon RR, Hunter KW, Threadgill DW, Pomp D.

Clin Exp Metastasis. 2010 Feb;27(2):107-16. doi: 10.1007/s10585-009-9302-7. Epub 2010 Feb 12.


Parent-of-origin effects on voluntary exercise levels and body composition in mice.

Kelly SA, Nehrenberg DL, Hua K, Gordon RR, Garland T Jr, Pomp D.

Physiol Genomics. 2010 Jan 8;40(2):111-20. doi: 10.1152/physiolgenomics.00139.2009. Epub 2009 Nov 10.


Genetic variation in the pleiotropic association between physical activity and body weight in mice.

Leamy LJ, Pomp D, Lightfoot JT.

Genet Sel Evol. 2009 Sep 23;41:41. doi: 10.1186/1297-9686-41-41.


Genetic variation for body weight change in mice in response to physical exercise.

Leamy LJ, Pomp D, Lightfoot JT.

BMC Genet. 2009 Sep 21;10:58. doi: 10.1186/1471-2156-10-58.


Dietary fat alters body composition, mammary development, and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors.

La Merrill M, Kuruvilla BS, Pomp D, Birnbaum LS, Threadgill DW.

Environ Health Perspect. 2009 Sep;117(9):1414-9. doi: 10.1289/ehp.0800530. Epub 2009 May 18. Erratum in: Environ Health Perspect. 2009 Oct;117(10):A434.


QTL underlying voluntary exercise in mice: interactions with the "mini muscle" locus and sex.

Nehrenberg DL, Wang S, Hannon RM, Garland T Jr, Pomp D.

J Hered. 2010 Jan-Feb;101(1):42-53. doi: 10.1093/jhered/esp066.

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