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Items: 1 to 50 of 207

1.

Combination of weekly topotecan and gemcitabine as a salvage treatment in patients with recurrent ovarian cancer: a phase I study.

Syrios J, Kouroussis C, Kotsakis A, Kentepozidis N, Kontopodis E, Kalbakis K, Vardakis N, Hatzidaki D, Polyzos A, Georgoulias V; GU Working Group of the Hellenic Oncology Research Group (HORG), Athens, Greece.

Minerva Ginecol. 2019 Feb 6. doi: 10.23736/S0026-4784.19.04249-7. [Epub ahead of print]

PMID:
30727721
2.

The lysine-specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer.

Rampias T, Karagiannis D, Avgeris M, Polyzos A, Kokkalis A, Kanaki Z, Kousidou E, Tzetis M, Kanavakis E, Stravodimos K, Manola KN, Pantelias GE, Scorilas A, Klinakis A.

EMBO Rep. 2019 Jan 21. pii: e46821. doi: 10.15252/embr.201846821. [Epub ahead of print]

PMID:
30665945
3.

Metallo-Cubosomes: Zinc-Functionalized Cubic Nanoparticles for Therapeutic Nucleotide Delivery.

Tajik-Ahmadabad B, Chollet L, White J, Separovic F, Polyzos A.

Mol Pharm. 2019 Feb 1. doi: 10.1021/acs.molpharmaceut.8b00890. [Epub ahead of print]

PMID:
30648870
4.

Regioselectivity of aryl radical attack onto isocyanates and isothiocyanates.

Weragoda GK, Pilkington RL, Polyzos A, O'Hair RAJ.

Org Biomol Chem. 2018 Nov 28;16(46):9011-9020. doi: 10.1039/c8ob02209g.

PMID:
30427050
5.

RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss.

Kosmidis S, Polyzos A, Harvey L, Youssef M, Denny CA, Dranovsky A, Kandel ER.

Cell Rep. 2018 Oct 23;25(4):959-973.e6. doi: 10.1016/j.celrep.2018.09.077.

6.

IFNα Impairs Autophagic Degradation of mtDNA Promoting Autoreactivity of SLE Monocytes in a STING-Dependent Fashion.

Gkirtzimanaki K, Kabrani E, Nikoleri D, Polyzos A, Blanas A, Sidiropoulos P, Makrigiannakis A, Bertsias G, Boumpas DT, Verginis P.

Cell Rep. 2018 Oct 23;25(4):921-933.e5. doi: 10.1016/j.celrep.2018.09.001.

7.

A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways.

Piragyte I, Clapes T, Polyzou A, Klein Geltink RI, Lefkopoulos S, Yin N, Cauchy P, Curtis JD, Klaeylé L, Langa X, Beckmann CCA, Wlodarski MW, Müller P, Van Essen D, Rambold A, Kapp FG, Mione M, Buescher JM, Pearce EL, Polyzos A, Trompouki E.

Nat Commun. 2018 Aug 6;9(1):3090. doi: 10.1038/s41467-018-05311-4.

8.

Radical Carbonylation Mediated by Continuous-Flow Visible-Light Photocatalysis: Access to 2,3-Dihydrobenzofurans.

Micic N, Polyzos A.

Org Lett. 2018 Aug 3;20(15):4663-4666. doi: 10.1021/acs.orglett.8b01971. Epub 2018 Jul 20.

PMID:
30028139
9.

Synthesis and Reactions of Benzannulated Spiroaminals: Tetrahydrospirobiquinolines.

Almond-Thynne J, White AJP, Polyzos A, Rzepa HS, Parsons PJ, Barrett AGM.

ACS Omega. 2017 Jul 31;2(7):3241-3249. doi: 10.1021/acsomega.7b00482. Epub 2017 Jul 7.

10.

Correction to Photocatalytic and Chemoselective Transfer Hydrogenation of Diarylimines in Batch and Continuous Flow.

van As DJ, Connell TU, Brzozowski M, Scully AD, Polyzos A.

Org Lett. 2018 Jul 20;20(14):4392. doi: 10.1021/acs.orglett.8b02023. Epub 2018 Jul 10. No abstract available.

PMID:
29989416
11.

Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells.

Alissafi T, Hatzioannou A, Mintzas K, Barouni RM, Banos A, Sormendi S, Polyzos A, Xilouri M, Wielockx B, Gogas H, Verginis P.

J Clin Invest. 2018 Aug 31;128(9):3840-3852. doi: 10.1172/JCI120888. Epub 2018 Aug 6.

12.

Perturbation of transcriptome in non-neoplastic salivary gland epithelial cell lines derived from patients with primary Sjögren's syndrome.

Vakrakou AG, Polyzos A, Kapsogeorgou EK, Thanos D, Manoussakis MN.

Data Brief. 2017 Dec 12;17:194-199. doi: 10.1016/j.dib.2017.12.023. eCollection 2018 Apr.

13.

Bidirectional Synthesis of Di- tert-butyl (2 S,6 S,8 S)- and (2 R,6 R,8 R)-1,7-Diazaspiro[5.5]undecane-2,8-dicarboxylate and Related Spirodiamines.

Almond-Thynne J, Han J, White AJP, Polyzos A, Parsons PJ, Barrett AGM.

J Org Chem. 2018 Jun 15;83(12):6783-6787. doi: 10.1021/acs.joc.8b00794. Epub 2018 Jun 1.

PMID:
29792022
14.

Hippocampal lipidome and transcriptome profile alterations triggered by acute exposure of mice to GSM 1800 MHz mobile phone radiation: An exploratory study.

Fragopoulou AF, Polyzos A, Papadopoulou MD, Sansone A, Manta AK, Balafas E, Kostomitsopoulos N, Skouroliakou A, Chatgilialoglu C, Georgakilas A, Stravopodis DJ, Ferreri C, Thanos D, Margaritis LH.

Brain Behav. 2018 Jun;8(6):e01001. doi: 10.1002/brb3.1001. Epub 2018 May 22.

15.

Full Karyotype Interphase Cell Analysis.

Baumgartner A, Ferlatte Hartshorne C, Polyzos AA, Weier HG, Weier JF, O'Brien B.

J Histochem Cytochem. 2018 Aug;66(8):595-606. doi: 10.1369/0022155418771613. Epub 2018 Apr 19.

16.

XJB-5-131-mediated improvement in physiology and behaviour of the R6/2 mouse model of Huntington's disease is age- and sex- dependent.

Polyzos AA, Wood NI, Williams P, Wipf P, Morton AJ, McMurray CT.

PLoS One. 2018 Apr 9;13(4):e0194580. doi: 10.1371/journal.pone.0194580. eCollection 2018.

17.

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.

Galanos P, Pappas G, Polyzos A, Kotsinas A, Svolaki I, Giakoumakis NN, Glytsou C, Pateras IS, Swain U, Souliotis VL, Georgakilas AG, Geacintov N, Scorrano L, Lukas C, Lukas J, Livneh Z, Lygerou Z, Chowdhury D, Sørensen CS, Bartek J, Gorgoulis VG.

Genome Biol. 2018 Mar 16;19(1):37. doi: 10.1186/s13059-018-1401-9.

18.

The Histone Variant MacroH2A Blocks Cellular Reprogramming by Inhibiting Mesenchymal-to-Epithelial Transition.

Pliatska M, Kapasa M, Kokkalis A, Polyzos A, Thanos D.

Mol Cell Biol. 2018 Apr 30;38(10). pii: e00669-17. doi: 10.1128/MCB.00669-17. Print 2018 May 15.

19.

A visible-light photocatalytic thiolation of aryl, heteroaryl and vinyl iodides.

Czyz ML, Weragoda GK, Monaghan R, Connell TU, Brzozowski M, Scully AD, Burton J, Lupton DW, Polyzos A.

Org Biomol Chem. 2018 Feb 28;16(9):1543-1551. doi: 10.1039/c8ob00238j.

PMID:
29431836
20.

Photocatalytic and Chemoselective Transfer Hydrogenation of Diarylimines in Batch and Continuous Flow.

van As DJ, Connell TU, Brzozowski M, Scully AD, Polyzos A.

Org Lett. 2018 Feb 16;20(4):905-908. doi: 10.1021/acs.orglett.7b03565. Epub 2018 Jan 30. Erratum in: Org Lett. 2018 Jul 20;20(14):4392.

PMID:
29381072
21.

Nab-paclitaxel as second-line treatment in advanced gastric cancer: a multicenter phase II study of the Hellenic Oncology Research Group.

Katsaounis P, Kotsakis A, Kentepozidis N, Polyzos A, Bakogeorgos M, Koinis F, Vamvakas L, Vardakis N, Kalbakis K, Boukovinas I, Varthalitis II, Prinarakis E, Georgoulias V, Souglakos J.

Ann Gastroenterol. 2018 Jan-Feb;31(1):65-70. doi: 10.20524/aog.2017.0215. Epub 2017 Nov 27.

22.

A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.

Komseli ES, Pateras IS, Krejsgaard T, Stawiski K, Rizou SV, Polyzos A, Roumelioti FM, Chiourea M, Mourkioti I, Paparouna E, Zampetidis CP, Gumeni S, Trougakos IP, Pefani DE, O'Neill E, Gagos S, Eliopoulos AG, Fendler W, Chowdhury D, Bartek J, Gorgoulis VG.

BMC Genomics. 2018 Jan 10;19(1):37. doi: 10.1186/s12864-017-4375-1.

23.

Weekly Paclitaxel and Carboplatin Plus Bevacizumab as First-Line Treatment of Metastatic Triple-Negative Breast Cancer. A Multicenter Phase II Trial by the Hellenic Oncology Research Group.

Saloustros E, Nikolaou M, Kalbakis K, Polyzos A, Christofillakis C, Kentepozidis N, Pistamaltzian N, Kourousis C, Vamvakas L, Georgoulias V, Mavroudis D.

Clin Breast Cancer. 2018 Feb;18(1):88-94. doi: 10.1016/j.clbc.2017.10.013. Epub 2017 Oct 24.

PMID:
29153775
24.

Impaired anti-inflammatory activity of PPARγ in the salivary epithelia of Sjögren's syndrome patients imposed by intrinsic NF-κB activation.

Vakrakou AG, Polyzos A, Kapsogeorgou EK, Thanos D, Manoussakis MN.

J Autoimmun. 2018 Jan;86:62-74. doi: 10.1016/j.jaut.2017.09.007. Epub 2017 Oct 14.

PMID:
29033144
25.

Amphiphilic lipopeptide significantly enhances uptake of charge-neutral splice switching morpholino oligonucleotide in spinal muscular atrophy patient-derived fibroblasts.

Tajik-Ahmadabad B, Polyzos A, Separovic F, Shabanpoor F.

Int J Pharm. 2017 Oct 30;532(1):21-28. doi: 10.1016/j.ijpharm.2017.08.116. Epub 2017 Aug 31.

PMID:
28864392
26.

Auxiliary-Directed C(sp3 )-H Arylation by Synergistic Photoredox and Palladium Catalysis.

Czyz ML, Lupton DW, Polyzos A.

Chemistry. 2017 Oct 17;23(58):14450-14453. doi: 10.1002/chem.201704045. Epub 2017 Sep 21.

PMID:
28862367
27.

Close encounters: Moving along bumps, breaks, and bubbles on expanded trinucleotide tracts.

Polyzos AA, McMurray CT.

DNA Repair (Amst). 2017 Aug;56:144-155. doi: 10.1016/j.dnarep.2017.06.017. Epub 2017 Jun 9. Review.

28.

Proteomic Analysis of Normal and Cancer Cervical Cell Lines Reveals Deregulation of Cytoskeleton-associated Proteins.

Pappa KI, Lygirou V, Kontostathi G, Zoidakis J, Makridakis M, Vougas K, Daskalakis G, Polyzos A, Anagnou NP.

Cancer Genomics Proteomics. 2017 Jul-Aug;14(4):253-266.

29.

Luminescence of a Transition Metal Complex Inside a Metamaterial Nanocavity.

Connell TU, Earl SK, Ng C, Roberts A, Davis TJ, White JM, Polyzos A, Gómez DE.

Small. 2017 Aug;13(32). doi: 10.1002/smll.201700692. Epub 2017 Jun 22.

PMID:
28639433
30.

Erratum to 'Exploring and exploiting the systemic effects of deregulated replication licensing' [Seminars in Cancer Biology 37-38C, (2016) 3-15].

Petrakis TG, Komseli ES, Papaioannou M, Vougas K, Polyzos A, Myrianthopoulos V, Mikros E, Trougakos IP, Thanos D, Branzei D, Townsend P, Gorgoulis VG.

Semin Cancer Biol. 2017 Apr;43:180. doi: 10.1016/j.semcancer.2017.02.002. Epub 2017 Feb 21. No abstract available.

PMID:
28254408
31.

A QCM-D and SAXS Study of the Interaction of Functionalised Lyotropic Liquid Crystalline Lipid Nanoparticles with siRNA.

Tajik-Ahmadabad B, Mechler A, Muir BW, McLean K, Hinton TM, Separovic F, Polyzos A.

Chembiochem. 2017 May 18;18(10):921-930. doi: 10.1002/cbic.201600613. Epub 2017 Apr 3.

PMID:
28233412
32.

Mobile-phone radiation-induced perturbation of gene-expression profiling, redox equilibrium and sporadic-apoptosis control in the ovary of Drosophila melanogaster.

Manta AK, Papadopoulou D, Polyzos AP, Fragopoulou AF, Skouroliakou AS, Thanos D, Stravopodis DJ, Margaritis LH.

Fly (Austin). 2017 Apr 3;11(2):75-95. doi: 10.1080/19336934.2016.1270487. Epub 2016 Dec 14.

33.

Pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta as regulators of angiogenesis and cancer.

Papadimitriou E, Pantazaka E, Castana P, Tsalios T, Polyzos A, Beis D.

Biochim Biophys Acta. 2016 Dec;1866(2):252-265. doi: 10.1016/j.bbcan.2016.09.007. Epub 2016 Sep 29. Review.

PMID:
27693125
34.

Biweekly Carboplatin Plus Gemcitabine as First-Line Treatment of Elderly Patients With Advanced Squamous Non-Small-cell Lung Cancer: A Multicenter Phase I-II Trial by the Hellenic Oncology Research Group.

Karampeazis A, Vamvakas L, Kentepozidis N, Polyzos A, Chandrinos V, Rigas G, Christofyllakis C, Kotsakis A, Hatzidaki D, Pallis AG, Georgoulias V.

Clin Lung Cancer. 2016 Nov;17(6):543-549. doi: 10.1016/j.cllc.2016.05.009. Epub 2016 Jun 2.

PMID:
27397849
35.

The chicken or the egg: mitochondrial dysfunction as a cause or consequence of toxicity in Huntington's disease.

Polyzos AA, McMurray CT.

Mech Ageing Dev. 2017 Jan;161(Pt A):181-197. doi: 10.1016/j.mad.2016.09.003. Epub 2016 Sep 12. Review.

36.

Salvage treatment with irinotecan/cisplatin versus pemetrexed/cisplatin in patients with non-small cell lung cancer pre-treated with a non-platinum-based regimen in the first-line setting: a randomized phase II study of the Hellenic Oncology Research Group (HORG).

Kentepozidis N, Economopoulou P, Christofyllakis C, Chelis L, Polyzos A, Vardakis N, Koinis F, Vamvakas L, Katsaounis P, Kalbakis K, Nikolaou C, Georgoulias V, Kotsakis A.

Clin Transl Oncol. 2017 Mar;19(3):317-325. doi: 10.1007/s12094-016-1532-y. Epub 2016 Aug 4.

PMID:
27492015
37.

Efficacy and tolerance of frontline bevacizumab-based chemotherapy for advanced non-small cell lung cancer patients: a multicenter, phase IV study of the Hellenic Oncology Research Group (HORG).

Matikas A, Kentepozidis Ν, Ardavanis A, Vaslamatzis M, Polyzos A, Emmanouilides Ch, Katsaounis P, Koinis F, Xynogalos S, Christopoulou A, Ziras N, Tegos T, Prinarakis E, Hatzidaki D, Georgoulias V, Kotsakis A; HORG’s Lung Cancer Working Group.

Cancer Chemother Pharmacol. 2016 Aug;78(2):369-76. doi: 10.1007/s00280-016-3094-7. Epub 2016 Jun 22.

PMID:
27335027
38.

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.

Galanos P, Vougas K, Walter D, Polyzos A, Maya-Mendoza A, Haagensen EJ, Kokkalis A, Roumelioti FM, Gagos S, Tzetis M, Canovas B, Igea A, Ahuja AK, Zellweger R, Havaki S, Kanavakis E, Kletsas D, Roninson IB, Garbis SD, Lopes M, Nebreda A, Thanos D, Blow JJ, Townsend P, Sørensen CS, Bartek J, Gorgoulis VG.

Nat Cell Biol. 2016 Jul;18(7):777-89. doi: 10.1038/ncb3378. Epub 2016 Jun 20.

PMID:
27323328
39.

Docetaxel plus gemcitabine versus gemcitabine in elderly patients with advanced non-small cell lung cancer and use of a geriatric assessment: Lessons from a prematurely closed Hellenic Oncology Research Group randomized phase III study.

Karampeazis A, Vamvakas L, Kotsakis A, Christophyllakis C, Kentepozidis N, Chandrinos V, Agelidou A, Polyzos A, Tsiafaki X, Hatzidaki D, Georgoulias V.

J Geriatr Oncol. 2017 Jan;8(1):23-30. doi: 10.1016/j.jgo.2016.05.002. Epub 2016 Jun 2.

PMID:
27264267
40.

Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes.

Polyzos A, Holt A, Brown C, Cosme C, Wipf P, Gomez-Marin A, Castro MR, Ayala-Peña S, McMurray CT.

Hum Mol Genet. 2016 May 1;25(9):1792-802. doi: 10.1093/hmg/ddw051. Epub 2016 Feb 21.

41.

Exploring and exploiting the systemic effects of deregulated replication licensing.

Petrakis TG, Komseli ES, Papaioannou M, Vougas K, Polyzos A, Myrianthopoulos V, Mikros E, Trougakos IP, Thanos D, Branzei D, Townsend P, Gorgoulis VG.

Semin Cancer Biol. 2016 Jun;37-38:3-15. doi: 10.1016/j.semcancer.2015.12.002. Epub 2015 Dec 17. Review. Erratum in: Semin Cancer Biol. 2017 Apr;43:180.

PMID:
26707000
42.

Profiling of Discrete Gynecological Cancers Reveals Novel Transcriptional Modules and Common Features Shared by Other Cancer Types and Embryonic Stem Cells.

Pappa KI, Polyzos A, Jacob-Hirsch J, Amariglio N, Vlachos GD, Loutradis D, Anagnou NP.

PLoS One. 2015 Nov 11;10(11):e0142229. doi: 10.1371/journal.pone.0142229. eCollection 2015.

43.

Transient generalized glucocorticoid hypersensitivity.

Nicolaides NC, Lamprokostopoulou A, Polyzos A, Kino T, Katsantoni E, Triantafyllou P, Christophoridis A, Katzos G, Dracopoulou M, Sertedaki A, Chrousos GP, Charmandari E.

Eur J Clin Invest. 2015 Dec;45(12):1306-15. doi: 10.1111/eci.12554. Epub 2015 Nov 20.

PMID:
26479047
44.

Continuous flow synthesis of a carbon-based molecular cage macrocycle via a three-fold homocoupling reaction.

Kitchin M, Konstas K, Sumby CJ, Czyz ML, Valente P, Hill MR, Polyzos A, Doonan CJ.

Chem Commun (Camb). 2015 Sep 28;51(75):14231-4. doi: 10.1039/c5cc05181a. Epub 2015 Aug 11.

PMID:
26260405
45.

A novel mutation of the calcium-sensing receptor gene in a Greek family from Nisyros.

Zapanti E, Polonifi A, Kokkinos M, Boutzios G, Kassi G, Nasiri Ansari N, Kassi E, Polyzos A.

Hormones (Athens). 2015 Apr-Jun;14(2):321-5. doi: 10.14310/horm.2002.1586.

46.

Composite macroH2A/NRF-1 Nucleosomes Suppress Noise and Generate Robustness in Gene Expression.

Lavigne MD, Vatsellas G, Polyzos A, Mantouvalou E, Sianidis G, Maraziotis I, Agelopoulos M, Thanos D.

Cell Rep. 2015 May 19;11(7):1090-101. doi: 10.1016/j.celrep.2015.04.022. Epub 2015 May 7.

47.

Sequential administration of vinorelbine plus cisplatin and bevacizumab followed by docetaxel plus gemcitabine and bevacizumab compared to docetaxel plus cisplatin and bevacizumab regimen as first-line therapy for advanced or metastatic non-squamous non-small cell lung cancer: A multicenter randomized phase II trial of the Hellenic Oncology Research Group (HORG).

Kotsakis A, Kentepozidis N, Emmanouilidis Ch, Polyzos A, Agelidou A, Vaslamatzis M, Chandrinos V, Agelaki S, Vamvakas L, Kalbakis K, Katsaounis P, Stoltidis D, Nintos G, Hatzidaki D, Vetsika EK, Mavroudis D, Georgoulias V.

Lung Cancer. 2015 Apr;88(1):57-62. doi: 10.1016/j.lungcan.2015.01.012. Epub 2015 Jan 23.

PMID:
25662596
48.

Flow chemistry: intelligent processing of gas-liquid transformations using a tube-in-tube reactor.

Brzozowski M, O'Brien M, Ley SV, Polyzos A.

Acc Chem Res. 2015 Feb 17;48(2):349-62. doi: 10.1021/ar500359m. Epub 2015 Jan 22. Review.

PMID:
25611216
49.

Maternal weight as an alternative determinant of the gestational day of Wistar rats housed in individually-ventilated cages.

Paronis E, Samara A, Polyzos A, Spyropoulos C, Kostomitsopoulos NG.

Lab Anim. 2015 Jul;49(3):188-95. doi: 10.1177/0023677214562846. Epub 2014 Dec 8.

PMID:
25488321
50.

The direct α-C(sp(3))-H functionalisation of N-aryl tetrahydroisoquinolines via an iron-catalysed aerobic nitro-Mannich reaction and continuous flow processing.

Brzozowski M, Forni JA, Paul Savage G, Polyzos A.

Chem Commun (Camb). 2015;51(2):334-7. doi: 10.1039/c4cc07913b.

PMID:
25407918

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