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Items: 50


B Cell Adaptive Immune Profile in Emphysema-Predominant COPD.

Sullivan JL, Bagevalu B, Glass C, Sholl L, Kraft M, Martinez FD, Bastarrika G, de-Torres JP, San José Estépar R, Guerra S, Polverino F.

Am J Respir Crit Care Med. 2019 Jul 26. doi: 10.1164/rccm.201903-0632LE. [Epub ahead of print] No abstract available.


CFTR regulates B cell activation and lymphoid follicle development.

Polverino F, Lu B, Quintero JR, Vargas SO, Patel AS, Owen CA, Gerard NP, Gerard C, Cernadas M.

Respir Res. 2019 Jul 1;20(1):133. doi: 10.1186/s12931-019-1103-1.


COPD: To Be or Not to Be, That is the Question.

Polverino F, Sam A, Guerra S.

Am J Med. 2019 May 30. pii: S0002-9343(19)30447-4. doi: 10.1016/j.amjmed.2019.04.047. [Epub ahead of print] Review.


Prognostic Validation Using GesEPOC 2017 Severity Criteria.

Cabrera López C, Casanova Macario C, Marín Trigo JM, de-Torres JP, Torres RS, González JM, Polverino F, Divo M, Pinto Plata V, Zulueta J, Callejas FJ, Celli B.

Arch Bronconeumol. 2019 Aug;55(8):409-413. doi: 10.1016/j.arbres.2018.12.002. Epub 2019 Feb 2. English, Spanish.


Deconvoluting Chronic Obstructive Pulmonary Disease: Are B Cells the Frontrunners?

Polverino F.

Am J Respir Crit Care Med. 2019 May 1;199(9):1170-1171. doi: 10.1164/rccm.201811-2093LE. No abstract available.


Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection.

Rojas-Quintero J, Wang X, Tipper J, Burkett PR, Zuñiga J, Ashtekar AR, Polverino F, Rout A, Yambayev I, Hernández C, Jimenez L, Ramírez G, Harrod KS, Owen CA.

JCI Insight. 2018 Dec 20;3(24). pii: 99022. doi: 10.1172/jci.insight.99022.


Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness.

Tartaglione G, Spaziano G, Sgambato M, Russo TP, Liparulo A, Esposito R, Mirra S, Filosa R, Roviezzo F, Polverino F, D'Agostino B.

Physiol Rep. 2018 Oct;6(20):e13906. doi: 10.14814/phy2.13906.


What is early COPD and why is it important?

Soriano JB, Polverino F, Cosio BG.

Eur Respir J. 2018 Dec 6;52(6). pii: 1801448. doi: 10.1183/13993003.01448-2018. Print 2018 Dec.


Beclin-1 regulates cigarette smoke-induced kidney injury in a murine model of chronic obstructive pulmonary disease.

Pabón MA, Patino E, Bhatia D, Rojas-Quintero J, Ma KC, Finkelsztein EJ, Osorio JC, Malick F, Polverino F, Owen CA, Ryter SW, Choi AM, Cloonan SM, Choi ME.

JCI Insight. 2018 Sep 20;3(18). pii: 99592. doi: 10.1172/jci.insight.99592. eCollection 2018 Sep 20.


Supplementation with Qter® and Creatine improves functional performance in COPD patients on long term oxygen therapy.

De Benedetto F, Pastorelli R, Ferrario M, de Blasio F, Marinari S, Brunelli L, Wouters EFM, Polverino F, Celli BR; Interdisciplinary Association for Research in Lung Disease (AIMAR) Study Group.

Respir Med. 2018 Sep;142:86-93. doi: 10.1016/j.rmed.2018.08.002. Epub 2018 Aug 7.


The Course of Lung Function in Middle-aged Heavy Smokers: Incidence and Time to Early Onset of Chronic Obstructive Pulmonary Disease.

Petersen H, Sood A, Polverino F, Owen CA, Pinto-Plata V, Celli BR, Tesfaigzi Y.

Am J Respir Crit Care Med. 2018 Dec 1;198(11):1449-1451. doi: 10.1164/rccm.201805-0861LE. No abstract available.


Club cell protein 16 (Cc16) deficiency increases inflamm-aging in the lungs of mice.

Laucho-Contreras ME, Polverino F, Rojas-Quintero J, Wang X, Owen CA.

Physiol Rep. 2018 Aug;6(15):e13797. doi: 10.14814/phy2.13797.


A Disintegrin and A Metalloproteinase-9 (ADAM9): A Novel Proteinase Culprit with Multifarious Contributions to COPD.

Wang X, Polverino F, Rojas-Quintero J, Zhang D, Sánchez J, Yambayev I, Lindqvist E, Virtala R, Djukanovic R, Davies DE, Wilson S, O'Donnell R, Cunoosamy D, Hazon P, Higham A, Singh D, Olsson H, Owen CA.

Am J Respir Crit Care Med. 2018 Jun 4. doi: 10.1164/rccm.201711-2300OC. [Epub ahead of print]


The Challenge of Controlling the COPD Epidemic: Unmet Needs.

Polverino F, Celli B.

Am J Med. 2018 Sep;131(9S):1-6. doi: 10.1016/j.amjmed.2018.05.001. Epub 2018 May 17. Review.


A Disintegrin and Metalloproteinase Domain-8: A Novel Protective Proteinase in Chronic Obstructive Pulmonary Disease.

Polverino F, Rojas-Quintero J, Wang X, Petersen H, Zhang L, Gai X, Higham A, Zhang D, Gupta K, Rout A, Yambayev I, Pinto-Plata V, Sholl LM, Cunoosamy D, Celli BR, Goldring J, Singh D, Tesfaigzi Y, Wedzicha J, Olsson H, Owen CA.

Am J Respir Crit Care Med. 2018 Nov 15;198(10):1254-1267. doi: 10.1164/rccm.201707-1331OC.


Gas exchange and breathing pattern in women with postmenopausal bone fragility.

Polverino F, de Torres JP, Santoriello C, Capuozzo A, Mauro I, Rojas-Quintero J, D'Agostino B, Pistolesi M, Celli B, Polverino M, Owen CA.

Respir Med. 2018 Apr;137:141-146. doi: 10.1016/j.rmed.2018.03.006. Epub 2018 Mar 7.


Chronic Obstructive Pulmonary Disease (COPD) as a disease of early aging: Evidence from the EpiChron Cohort.

Divo MJ, Celli BR, Poblador-Plou B, Calderón-Larrañaga A, de-Torres JP, Gimeno-Feliu LA, Bertó J, Zulueta JJ, Casanova C, Pinto-Plata VM, Cabrera-Lopez C, Polverino F, Carmona Píréz J, Prados-Torres A, Marin JM; EpiChron—BODE Collaborative Group.

PLoS One. 2018 Feb 22;13(2):e0193143. doi: 10.1371/journal.pone.0193143. eCollection 2018.


COPD as an endothelial disorder: endothelial injury linking lesions in the lungs and other organs? (2017 Grover Conference Series).

Polverino F, Celli BR, Owen CA.

Pulm Circ. 2018 Jan-Mar;8(1):2045894018758528. doi: 10.1177/2045894018758528.


Best of Milan 2017-repair of the emphysematous lung: mesenchymal stromal cell and matrix.

Polverino F.

J Thorac Dis. 2017 Nov;9(Suppl 16):S1544-S1547. doi: 10.21037/jtd.2017.11.41. No abstract available.


Comparison of the 2017 and 2015 Global Initiative for Chronic Obstructive Lung Disease Reports. Impact on Grouping and Outcomes.

Cabrera López C, Casanova Macario C, Marín Trigo JM, de-Torres JP, Sicilia Torres R, González JM, Polverino F, Divo M, Pinto Plata V, Zulueta JJ, Celli B.

Am J Respir Crit Care Med. 2018 Feb 15;197(4):463-469. doi: 10.1164/rccm.201707-1363OC.


Role of interferon regulatory factor 1 in governing Treg depletion, Th1 polarization, inflammasome activation and antitumor efficacy of cyclophosphamide.

Buccione C, Fragale A, Polverino F, Ziccheddu G, Aricò E, Belardelli F, Proietti E, Battistini A, Moschella F.

Int J Cancer. 2018 Mar 1;142(5):976-987. doi: 10.1002/ijc.31083. Epub 2017 Oct 16.


Chronic Obstructive Pulmonary Disease: Breathing New Life into Old Cardiovascular Drugs?

Polverino F, Celli BR, Owen CA.

Ann Am Thorac Soc. 2017 Nov;14(11):1718. doi: 10.1513/AnnalsATS.201707-613LE. No abstract available.


Reply to Voelkel: Cigarette Smoke Is an Endothelial Cell Toxin.

Polverino F, Celli BR, Owen CA.

Am J Respir Crit Care Med. 2018 Jan 15;197(2):274-275. doi: 10.1164/rccm.201707-1381LE. No abstract available.


A Pilot Study Linking Endothelial Injury in Lungs and Kidneys in Chronic Obstructive Pulmonary Disease.

Polverino F, Laucho-Contreras ME, Petersen H, Bijol V, Sholl LM, Choi ME, Divo M, Pinto-Plata V, Chetta A, Tesfaigzi Y, Celli BR, Owen CA.

Am J Respir Crit Care Med. 2017 Jun 1;195(11):1464-1476. doi: 10.1164/rccm.201609-1765OC.


B cells in chronic obstructive pulmonary disease: moving to center stage.

Polverino F, Seys LJ, Bracke KR, Owen CA.

Am J Physiol Lung Cell Mol Physiol. 2016 Oct 1;311(4):L687-L695. doi: 10.1152/ajplung.00304.2016. Epub 2016 Aug 19. Review.


Acid-base balance, serum electrolytes and need for non-invasive ventilation in patients with hypercapnic acute exacerbation of chronic obstructive pulmonary disease admitted to an internal medicine ward.

Schiavo A, Renis M, Polverino M, Iannuzzi A, Polverino F.

Multidiscip Respir Med. 2016 May 25;11:23. doi: 10.1186/s40248-016-0063-2. eCollection 2016.


Juniors' voice at the ERS International Congress, Amsterdam 2015: Juniors' voice.

Polverino F, Longhini F, Vanaudenaerde B, Bikov A, Aamli A, Singanayagam A, Kahn N, Boots A, Skoczynski S.

Breathe (Sheff). 2015 Dec;11(4):303-5. doi: 10.1183/20734735.010815.


Increased expression of A Proliferation-inducing Ligand (APRIL) in lung leukocytes and alveolar epithelial cells in COPD patients with non small cell lung cancer: a possible link between COPD and lung cancer?

Polverino F, Laucho-Contreras M, Rojas Quintero J, Divo M, Pinto-Plata V, Sholl L, de-Torres JP, Celli BR, Owen CA.

Multidiscip Respir Med. 2016 Apr 4;11:17. doi: 10.1186/s40248-016-0051-6. eCollection 2016.


Simplifying the guidelines: The 10 COPD commandments.

Marin JM, Cote C, Casanova C, Pinto-Plata V, Montes de Oca M, Divo MJ, de Torres JP, Zulueta J, Cabrera C, Carrizo S, Polverino F, Celli BR; En Representación del Grupo BODE.

Arch Bronconeumol. 2016 Apr;52(4):179-80. doi: 10.1016/j.arbres.2016.01.012. Epub 2016 Mar 10. English, Spanish. No abstract available.


A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-Catenin.

Jiang Z, Lao T, Qiu W, Polverino F, Gupta K, Guo F, Mancini JD, Naing ZZ, Cho MH, Castaldi PJ, Sun Y, Yu J, Laucho-Contreras ME, Kobzik L, Raby BA, Choi AM, Perrella MA, Owen CA, Silverman EK, Zhou X.

Am J Respir Crit Care Med. 2016 Jul 15;194(2):185-97. doi: 10.1164/rccm.201505-0999OC.


Club Cell Protein 16 (CC16) Augmentation: A Potential Disease-modifying Approach for Chronic Obstructive Pulmonary Disease (COPD).

Laucho-Contreras ME, Polverino F, Tesfaigzi Y, Pilon A, Celli BR, Owen CA.

Expert Opin Ther Targets. 2016 Jul;20(7):869-83. doi: 10.1517/14728222.2016.1139084. Epub 2016 Feb 11. Review.


Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice.

Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabón MA, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, Chen ZH, Goldklang MP, Yuan GC, Moore SC, Demeo DL, Rouault TA, D'Armiento JM, Schon EA, Manfredi G, Quackenbush J, Mahmood A, Silverman EK, Owen CA, Choi AM.

Nat Med. 2016 Feb;22(2):163-74. doi: 10.1038/nm.4021. Epub 2016 Jan 11.


B Cell-Activating Factor. An Orchestrator of Lymphoid Follicles in Severe Chronic Obstructive Pulmonary Disease.

Polverino F, Cosio BG, Pons J, Laucho-Contreras M, Tejera P, Iglesias A, Rios A, Jahn A, Sauleda J, Divo M, Pinto-Plata V, Sholl L, Rosas IO, Agustí A, Celli BR, Owen CA.

Am J Respir Crit Care Med. 2015 Sep 15;192(6):695-705. doi: 10.1164/rccm.201501-0107OC.


Haploinsufficiency of Hedgehog interacting protein causes increased emphysema induced by cigarette smoke through network rewiring.

Lao T, Glass K, Qiu W, Polverino F, Gupta K, Morrow J, Mancini JD, Vuong L, Perrella MA, Hersh CP, Owen CA, Quackenbush J, Yuan GC, Silverman EK, Zhou X.

Genome Med. 2015 Feb 14;7(1):12. doi: 10.1186/s13073-015-0137-3. eCollection 2015.


Protective role for club cell secretory protein-16 (CC16) in the development of COPD.

Laucho-Contreras ME, Polverino F, Gupta K, Taylor KL, Kelly E, Pinto-Plata V, Divo M, Ashfaq N, Petersen H, Stripp B, Pilon AL, Tesfaigzi Y, Celli BR, Owen CA.

Eur Respir J. 2015 Jun;45(6):1544-56. doi: 10.1183/09031936.00134214. Epub 2015 Feb 19.


A novel nonhuman primate model of cigarette smoke-induced airway disease.

Polverino F, Doyle-Eisele M, McDonald J, Wilder JA, Royer C, Laucho-Contreras M, Kelly EM, Divo M, Pinto-Plata V, Mauderly J, Celli BR, Tesfaigzi Y, Owen CA.

Am J Pathol. 2015 Mar;185(3):741-55. doi: 10.1016/j.ajpath.2014.11.006. Epub 2014 Dec 24.


ADAM9 is a novel product of polymorphonuclear neutrophils: regulation of expression and contributions to extracellular matrix protein degradation during acute lung injury.

Roychaudhuri R, Hergrueter AH, Polverino F, Laucho-Contreras ME, Gupta K, Borregaard N, Owen CA.

J Immunol. 2014 Sep 1;193(5):2469-82. doi: 10.4049/jimmunol.1303370. Epub 2014 Jul 25.


Effects of sex hormones on bronchial reactivity during the menstrual cycle.

Matteis M, Polverino F, Spaziano G, Roviezzo F, Santoriello C, Sullo N, Bucci MR, Rossi F, Polverino M, Owen CA, D'Agostino B.

BMC Pulm Med. 2014 Jul 1;14:108. doi: 10.1186/1471-2466-14-108.


Idiopathic pulmonary fibrosis and coronary artery disease.

Cicchitto G, Musella V, Acitorio M, Capuano N, Fiorenzano G, Owen CA, Polverino M, Polverino F.

Multidiscip Respir Med. 2014 May 30;9(1):31. doi: 10.1186/2049-6958-9-31. eCollection 2014.


Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (MMP-8) in patients with idiopathic pulmonary fibrosis.

Craig VJ, Polverino F, Laucho-Contreras ME, Shi Y, Liu Y, Osorio JC, Tesfaigzi Y, Pinto-Plata V, Gochuico BR, Rosas IO, Owen CA.

PLoS One. 2014 May 14;9(5):e97485. doi: 10.1371/journal.pone.0097485. eCollection 2014.


Recumbent deoxygenation in mild/moderate liver cirrhosis: the "clinodeoxia". The ortho-clino paradigm.

Polverino F, Santoriello C, Andò F, Girbino G, Cappetta D, D'Agostino B, Vatrella A, Polverino M, Milic-Emili J.

Respir Med. 2014 Jul;108(7):1040-8. doi: 10.1016/j.rmed.2014.04.003. Epub 2014 Apr 15.


C-reactive protein and carotid intima-media thickness in children with sleep disordered breathing.

Iannuzzi A, Licenziati MR, De Michele F, Verga MC, Santoriello C, Di Buono L, Renis M, Lembo L, D'Agostino B, Cappetta D, Polverino M, Polverino F.

J Clin Sleep Med. 2013 May 15;9(5):493-8. doi: 10.5664/jcsm.2674.


Adam8 limits the development of allergic airway inflammation in mice.

Knolle MD, Nakajima T, Hergrueter A, Gupta K, Polverino F, Craig VJ, Fyfe SE, Zahid M, Permaul P, Cernadas M, Montano G, Tesfaigzi Y, Sholl L, Kobzik L, Israel E, Owen CA.

J Immunol. 2013 Jun 15;190(12):6434-49. doi: 10.4049/jimmunol.1202329. Epub 2013 May 13.


Voice box symptoms: a hitherto unknown presentation of pulmonary embolism.

Polverino F, Ricciardi M, Polverino M, Santoriello C, Palladino R, Pistolesi M.

Am J Respir Crit Care Med. 2013 Jan 1;187(1):108-10. No abstract available.


Skeletal muscle oxidative metabolism in an animal model of pulmonary emphysema: formoterol and skeletal muscle dysfunction.

Sullo N, Roviezzo F, Matteis M, Spaziano G, Del Gaudio S, Lombardi A, Lucattelli M, Polverino F, Lungarella G, Cirino G, Rossi F, D'Agostino B.

Am J Respir Cell Mol Biol. 2013 Feb;48(2):198-203. doi: 10.1165/rcmb.2012-0167OC. Epub 2012 Nov 9.


Anatomy and neuro-pathophysiology of the cough reflex arc.

Polverino M, Polverino F, Fasolino M, Andò F, Alfieri A, De Blasio F.

Multidiscip Respir Med. 2012 Jun 18;7(1):5. doi: 10.1186/2049-6958-7-5.


A novel insight into adaptive immunity in chronic obstructive pulmonary disease: B cell activating factor belonging to the tumor necrosis factor family.

Polverino F, Baraldo S, Bazzan E, Agostini S, Turato G, Lunardi F, Balestro E, Damin M, Papi A, Maestrelli P, Calabrese F, Saetta M.

Am J Respir Crit Care Med. 2010 Oct 15;182(8):1011-9. doi: 10.1164/rccm.200911-1700OC. Epub 2010 Jun 25.


Impaired exercise performance in systemic sclerosis and its clinical correlations.

Cuomo G, Santoriello C, Polverino F, Ruocco L, Valentini G, Polverino M.

Scand J Rheumatol. 2010 Aug;39(4):330-5. doi: 10.3109/03009740903555358.


Exercise capacity and cytochrome oxidase activity in muscle mitochondria of COPD patients.

D'Agostino B, Polverino M, Cirino G, Lombardi A, Grassi B, Sullo N, Santoriello C, Polverino F, Orlotti D, Matteis M, Rossi F.

Respir Med. 2010 Jan;104(1):83-90. doi: 10.1016/j.rmed.2009.07.016. Epub 2009 Aug 27.


Sexual intercourse and respiratory failure.

Polverino F, Santoriello C, De Sio V, Andò F, de Blasio F, Polverino M.

Respir Med. 2008 Jun;102(6):927-31. doi: 10.1016/j.rmed.2008.02.013. Epub 2008 Apr 3.

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