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Items: 14

1.

Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation.

Harmange JC, Weiss MM, Germain J, Polverino AJ, Borg G, Bready J, Chen D, Choquette D, Coxon A, DeMelfi T, DiPietro L, Doerr N, Estrada J, Flynn J, Graceffa RF, Harriman SP, Kaufman S, La DS, Long A, Martin MW, Neervannan S, Patel VF, Potashman M, Regal K, Roveto PM, Schrag ML, Starnes C, Tasker A, Teffera Y, Wang L, White RD, Whittington DA, Zanon R.

J Med Chem. 2008 Mar 27;51(6):1649-67. doi: 10.1021/jm701097z. Epub 2008 Mar 7.

PMID:
18324761
2.

Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors.

Weiss MM, Harmange JC, Polverino AJ, Bauer D, Berry L, Berry V, Borg G, Bready J, Chen D, Choquette D, Coxon A, DeMelfi T, Doerr N, Estrada J, Flynn J, Graceffa RF, Harriman SP, Kaufman S, La DS, Long A, Neervannan S, Patel VF, Potashman M, Regal K, Roveto PM, Schrag ML, Starnes C, Tasker A, Teffera Y, Whittington DA, Zanon R.

J Med Chem. 2008 Mar 27;51(6):1668-80. doi: 10.1021/jm701098w. Epub 2008 Mar 7.

PMID:
18324759
3.

Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis.

La DS, Belzile J, Bready JV, Coxon A, DeMelfi T, Doerr N, Estrada J, Flynn JC, Flynn SR, Graceffa RF, Harriman SP, Larrow JF, Long AM, Martin MW, Morrison MJ, Patel VF, Roveto PM, Wang L, Weiss MM, Whittington DA, Teffera Y, Zhao Z, Polverino AJ, Harmange JC.

J Med Chem. 2008 Mar 27;51(6):1695-705. doi: 10.1021/jm701129j. Epub 2008 Feb 27.

PMID:
18311900
4.

Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo.

Lacey DL, Tan HL, Lu J, Kaufman S, Van G, Qiu W, Rattan A, Scully S, Fletcher F, Juan T, Kelley M, Burgess TL, Boyle WJ, Polverino AJ.

Am J Pathol. 2000 Aug;157(2):435-48.

5.

Ceramide second messengers and ceramide assays.

Watts JD, Aebersold R, Polverino AJ, Patterson SD, Gu M.

Trends Biochem Sci. 1999 Jun;24(6):228. No abstract available.

PMID:
10366850
6.
7.

Fas-induced apoptosis of T cells occurs independently of ceramide generation.

Watts JD, Gu M, Polverino AJ, Patterson SD, Aebersold R.

Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7292-6.

8.
9.

Oncogenic ras triggers the activation of 42-kDa mitogen-activated protein kinase in extracts of quiescent Xenopus oocytes.

Shibuya EK, Polverino AJ, Chang E, Wigler M, Ruderman JV.

Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9831-5.

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12.

On the source of the vasopressin-induced increases in diacylglycerol in hepatocytes.

Polverino AJ, Barritt GJ.

Biochim Biophys Acta. 1988 Jun 8;970(1):75-82.

PMID:
3130896
14.

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