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Items: 1 to 50 of 149


HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING.

Luo X, Donnelly CR, Gong W, Heath BR, Hao Y, Donnelly LA, Moghbeli T, Tan YS, Lin X, Bellile E, Kansy BA, Carey TE, Brenner JC, Cheng L, Polverini PJ, Morgan MA, Wen H, Prince ME, Ferris RL, Xie Y, Young S, Wolf GT, Chen Q, Lei YL.

J Clin Invest. 2019 Dec 24. pii: 129497. doi: 10.1172/JCI129497. [Epub ahead of print]


A History of Innovations in the Diagnosis and Treatment of Oral and Head and Neck Cancer.

Polverini PJ, Lingen MW.

J Dent Res. 2019 May;98(5):489-497. doi: 10.1177/0022034519833645.


UM-HACC-2A: MYB-NFIB fusion-positive human adenoid cystic carcinoma cell line.

Warner KA, Oklejas AE, Pearson AT, Zhang Z, Wu W, Divi V, Rodriguez-Ramirez C, Castilho RM, Polverini PJ, Nör JE.

Oral Oncol. 2018 Dec;87:21-28. doi: 10.1016/j.oraloncology.2018.10.012. Epub 2018 Oct 18.


Advancing Dental Education in the 21st Century: Phase 2 Report on Strategic Analysis and Recommendations.

Formicola AJ, Bailit HL, Weintraub JA, Fried JL, Polverini PJ.

J Dent Educ. 2018 Oct;82(10):eS1-eS32. doi: 10.21815/JDE.018.109.


Personalized medicine and the future of dental practice.

Polverini PJ.

Per Med. 2018 Nov;15(6):449-451. doi: 10.2217/pme-2018-0055. Epub 2018 Sep 27. No abstract available.


Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine.

Tan YS, Sansanaphongpricha K, Xie Y, Donnelly CR, Luo X, Heath BR, Zhao X, Bellile E, Hu H, Chen H, Polverini PJ, Chen Q, Young S, Carey TE, Nör JE, Ferris RL, Wolf GT, Sun D, Lei YL.

Clin Cancer Res. 2018 Sep 1;24(17):4242-4255. doi: 10.1158/1078-0432.CCR-17-2807. Epub 2018 May 16.


Precision Therapy of Head and Neck Squamous Cell Carcinoma.

Polverini PJ, D'Silva NJ, Lei YL.

J Dent Res. 2018 Jun;97(6):614-621. doi: 10.1177/0022034518769645. Epub 2018 Apr 12. Review.


Integrative and collaborative care models between pediatric oral health and primary care providers: a scoping review of the literature.

Gauger TL, Prosser LA, Fontana M, Polverini PJ.

J Public Health Dent. 2018 Jun;78(3):246-256. doi: 10.1111/jphd.12267. Epub 2018 Mar 30.


Research and Discovery Science and the Future of Dental Education and Practice.

Polverini PJ, Krebsbach PH.

J Dent Educ. 2017 Sep;81(9):eS97-eS107. doi: 10.21815/JDE.017.040.


Oral Health Research and Scholarship in 2040: Executive Summary.

Polverini PJ.

J Dent Educ. 2017 Sep;81(9):1137-1143. doi: 10.21815/JDE.017.070.


Expanding the Research Capacity of Dental Schools: Are We There Yet?

Polverini PJ, Lingen MW.

J Dent Res. 2017 Jan;96(1):8-9. doi: 10.1177/0022034516680557. No abstract available.


The vital role of research funding in preserving the oral health of the public and the dental profession.

Feinberg M, Garcia LT, Polverini PJ, Fox CH, Valachovic RW.

J Am Dent Assoc. 2015 Jun;146(6):355-6. doi: 10.1016/j.adaj.2015.03.022. No abstract available.


Endothelial interleukin-6 defines the tumorigenic potential of primary human cancer stem cells.

Krishnamurthy S, Warner KA, Dong Z, Imai A, Nör C, Ward BB, Helman JI, Taichman RS, Bellile EL, McCauley LK, Polverini PJ, Prince ME, Wicha MS, Nör JE.

Stem Cells. 2014 Nov;32(11):2845-57. doi: 10.1002/stem.1793.


Glucose-regulated protein 78 (Grp78) confers chemoresistance to tumor endothelial cells under acidic stress.

Visioli F, Wang Y, Alam GN, Ning Y, Rados PV, Nör JE, Polverini PJ.

PLoS One. 2014 Jun 25;9(6):e101053. doi: 10.1371/journal.pone.0101053. eCollection 2014.


Clinical application of genetics to guide prevention and treatment of oral diseases.

Kornman KS, Polverini PJ.

Clin Genet. 2014 Jul;86(1):44-9. doi: 10.1111/cge.12396. Epub 2014 May 10. Review.


Why integrating research and scholarship into dental education matters.

Polverini PJ.

J Dent Educ. 2014 Mar;78(3):332-3. No abstract available.


The G protein-coupled receptor GALR2 promotes angiogenesis in head and neck cancer.

Banerjee R, Van Tubergen EA, Scanlon CS, Vander Broek R, Lints JP, Liu M, Russo N, Inglehart RC, Wang Y, Polverini PJ, Kirkwood KL, D'Silva NJ.

Mol Cancer Ther. 2014 May;13(5):1323-33. doi: 10.1158/1535-7163.MCT-13-0904. Epub 2014 Feb 25.


U-M School of Dentistry: transitions.

Polverini PJ.

J Mich Dent Assoc. 2013 Sep;95(9):54, 56-9. No abstract available.


Translational genetics: advancing fronts for craniofacial health.

D'Souza RN, Dunnwald M, Frazier-Bowers S, Polverini PJ, Wright JT, de Rouen T, Vieira AR; Translational Genetics Meeting Group.

J Dent Res. 2013 Dec;92(12):1058-64. doi: 10.1177/0022034513507954. Epub 2013 Oct 4. Review. Erratum in: J Dent Res. 2014 Apr;93(4):425. Dunnvald, M [corrected to Dunnwald, M]; Multiple investigator names added.


Amino acid deprivation promotes tumor angiogenesis through the GCN2/ATF4 pathway.

Wang Y, Ning Y, Alam GN, Jankowski BM, Dong Z, Nör JE, Polverini PJ.

Neoplasia. 2013 Aug;15(8):989-97.


Ensuring that research and discovery remain core values of dentistry.

Polverini PJ.

J Dent Res. 2013 Jun;92(6):483-4. doi: 10.1177/0022034513487213. No abstract available.


UDM, U-M dental school deans respond to 'change' editorial.

Aksu MN, Polverini PJ.

J Mich Dent Assoc. 2013 Feb;95(2):11. No abstract available.


Authors' response.

D'Souza RN, Ebersole JL, Fox CH, Polverini PJ, Scannapieco FA.

J Am Dent Assoc. 2013 Feb;144(2):131-2. No abstract available.


U-M School of Dentistry: synergy in action.

Polverini PJ.

J Mich Dent Assoc. 2012 Sep;94(9):64-7. No abstract available.


How practicing dentists can shape dental research: The American Association for Dental Research's vision for the future.

D'Souza RN, Ebersole JL, Fox CH, Polverini PJ, Scannapieco FA.

J Am Dent Assoc. 2012 Oct;143(10):1069-71. No abstract available.


The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathway.

Wang Y, Alam GN, Ning Y, Visioli F, Dong Z, Nör JE, Polverini PJ.

Cancer Res. 2012 Oct 15;72(20):5396-406. doi: 10.1158/0008-5472.CAN-12-0474. Epub 2012 Aug 20.


A curriculum for the new dental practitioner: preparing dentists for a prospective oral health care environment.

Polverini PJ.

Am J Public Health. 2012 Feb;102(2):e1-3. doi: 10.2105/AJPH.2011.300505. Epub 2011 Dec 15.


University of Michigan School of Dentistry: engagement and connections.

Polverini PJ.

J Mich Dent Assoc. 2011 Sep;93(9):34-7. No abstract available.


Endothelial cell Bcl-2 and lymph node metastasis in patients with oral squamous cell carcinoma.

Tarquinio SB, Zhang Z, Neiva KG, Polverini PJ, Nör JE.

J Oral Pathol Med. 2012 Feb;41(2):124-30. doi: 10.1111/j.1600-0714.2011.01081.x. Epub 2011 Sep 21.


Shaping the future of the dental profession through research and discovery.

Polverini PJ.

J Dent Res. 2011 Mar;90(3):281-2. doi: 10.1177/0022034510397547. Epub 2011 Jan 11. No abstract available.


Creation of a scholars program in dental leadership (SPDL) for dental and dental hygiene students.

Taichman RS, Green TG, Polverini PJ.

J Dent Educ. 2009 Oct;73(10):1139-43.


Arsenic trioxide enhances the therapeutic efficacy of radiation treatment of oral squamous carcinoma while protecting bone.

Kumar P, Gao Q, Ning Y, Wang Z, Krebsbach PH, Polverini PJ.

Mol Cancer Ther. 2008 Jul;7(7):2060-9. doi: 10.1158/1535-7163.MCT-08-0287.


Endothelial cells expressing Bcl-2 promotes tumor metastasis by enhancing tumor angiogenesis, blood vessel leakiness and tumor invasion.

Kumar P, Ning Y, Polverini PJ.

Lab Invest. 2008 Jul;88(7):740-9. doi: 10.1038/labinvest.2008.46. Epub 2008 May 19.


Engineering tumors with 3D scaffolds.

Fischbach C, Chen R, Matsumoto T, Schmelzle T, Brugge JS, Polverini PJ, Mooney DJ.

Nat Methods. 2007 Oct;4(10):855-60. Epub 2007 Sep 2.


Quantification of human angiogenesis in immunodeficient mice using a photon counting-based method.

Dong Z, Neiva KG, Jin T, Zhang Z, Hall DE, Mooney DJ, Polverini PJ, Nör JE.

Biotechniques. 2007 Jul;43(1):73-7.


Unidirectional crosstalk between Bcl-xL and Bcl-2 enhances the angiogenic phenotype of endothelial cells.

Karl E, Zhang Z, Dong Z, Neiva KG, Soengas MS, Koch AE, Polverini PJ, Núñez G, Nör JE.

Cell Death Differ. 2007 Sep;14(9):1657-66. Epub 2007 Jun 15.


Bcl-2 protects endothelial cells against gamma-radiation via a Raf-MEK-ERK-survivin signaling pathway that is independent of cytochrome c release.

Kumar P, Coltas IK, Kumar B, Chepeha DB, Bradford CR, Polverini PJ.

Cancer Res. 2007 Feb 1;67(3):1193-202.


The response of VEGF-stimulated endothelial cells to angiostatic molecules is substrate-dependent.

Addison CL, Nör JE, Zhao H, Linn SA, Polverini PJ, Delaney CE.

BMC Cell Biol. 2005 Oct 31;6:38.


Epstein-Barr virus lytic infection is required for efficient production of the angiogenesis factor vascular endothelial growth factor in lymphoblastoid cell lines.

Hong GK, Kumar P, Wang L, Damania B, Gulley ML, Delecluse HJ, Polverini PJ, Kenney SC.

J Virol. 2005 Nov;79(22):13984-92.


Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling.

Zeng Q, Li S, Chepeha DB, Giordano TJ, Li J, Zhang H, Polverini PJ, Nor J, Kitajewski J, Wang CY.

Cancer Cell. 2005 Jul;8(1):13-23.


Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines.

Karl E, Warner K, Zeitlin B, Kaneko T, Wurtzel L, Jin T, Chang J, Wang S, Wang CY, Strieter RM, Nunez G, Polverini PJ, Nör JE.

Cancer Res. 2005 Jun 15;65(12):5063-9.


Activation of Latent TGF-β1 by Thrombospondin-1 is a Major Component of Wound Repair.

Nör JE, Dipietro L, Murphy-Ullrich JE, Hynes RO, Lawler J, Polverini PJ.

Oral Biosci Med. 2005;2(2):153-161.


CXC chemokines mechanism of action in regulating tumor angiogenesis.

Moore BB, Arenberg DA, Addison CL, Keane MP, Polverini PJ, Strieter RM.

Angiogenesis. 1998;2(2):123-34.


Angiogenesis induced by tumor necrosis factor-agr; is mediated by alpha4 integrins.

Vanderslice P, Munsch CL, Rachal E, Erichsen D, Sughrue KM, Truong AN, Wygant JN, McIntyre BW, Eskin SG, Tilton RG, Polverini PJ.

Angiogenesis. 1998;2(3):265-75.


Role of endothelial cell survival and death signals in angiogenesis.

Nör JE, Polverini PJ.

Angiogenesis. 1999;3(2):101-16.


Rap1, a small GTP-binding protein is upregulated during arrest of proliferation in human keratinocytes.

D'Silva NJ, Mitra RS, Zhang Z, Kurnit DM, Babcock CR, Polverini PJ, Carey TE.

J Cell Physiol. 2003 Sep;196(3):532-40.


Growth of human blood vessels in severe combined immunodeficient mice. A new in vivo model system of angiogenesis.

Polverini PJ, Nör JE, Peters MC, Mooney DJ.

Methods Mol Med. 2003;78:161-77. No abstract available.


Differential angiogenic and proliferative activity of surgical and burn wound fluids.

Nissen NN, Gamelli RL, Polverini PJ, DiPietro LA.

J Trauma. 2003 Jun;54(6):1205-10; discussion 1211.


Role of vascular endothelial growth factor in bone marrow stromal cell modulation of endothelial cells.

Kaigler D, Krebsbach PH, Polverini PJ, Mooney DJ.

Tissue Eng. 2003 Feb;9(1):95-103.

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