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Items: 22


Metformin Suppressed CXCL8 Expression and Cell Migration in HEK293/TLR4 Cell Line.

Xiao Z, Wu W, Poltoratsky V.

Mediators Inflamm. 2017;2017:6589423. doi: 10.1155/2017/6589423. Epub 2017 Sep 24.


N,N-Dimethylacetamide Significantly Attenuates LPS- and TNFα-Induced Proinflammatory Responses Via Inhibition of the Nuclear Factor Kappa B Pathway.

Pekson R, Poltoratsky V, Gorasiya S, Sundaram S, Ashby CR, Vancurova I, Reznik SE.

Mol Med. 2016 Dec;22:747-758. doi: 10.2119/molmed.2016.00017. Epub 2016 Oct 24.


Rev1 is a base excision repair enzyme with 5'-deoxyribose phosphate lyase activity.

Prasad R, Poltoratsky V, Hou EW, Wilson SH.

Nucleic Acids Res. 2016 Dec 15;44(22):10824-10833. Epub 2016 Sep 28.


Bortezomib inhibits expression of TGF-β1, IL-10, and CXCR4, resulting in decreased survival and migration of cutaneous T cell lymphoma cells.

Chang TP, Poltoratsky V, Vancurova I.

J Immunol. 2015 Mar 15;194(6):2942-53. doi: 10.4049/jimmunol.1402610. Epub 2015 Feb 13.


Analysis of LPS-induced, NFκB-dependent interleukin-8 transcription in kidney embryonic cell line expressing TLR4 using luciferase assay.

Yunusova T, Akhtar M, Poltoratsky V.

Methods Mol Biol. 2014;1172:305-14. doi: 10.1007/978-1-4939-0928-5_28.


Proteasome inhibition increases recruitment of IκB kinase β (IKKβ), S536P-p65, and transcription factor EGR1 to interleukin-8 (IL-8) promoter, resulting in increased IL-8 production in ovarian cancer cells.

Singha B, Gatla HR, Manna S, Chang TP, Sanacora S, Poltoratsky V, Vancura A, Vancurova I.

J Biol Chem. 2014 Jan 31;289(5):2687-700. doi: 10.1074/jbc.M113.502641. Epub 2013 Dec 11.


Evidence for abasic site sugar phosphate-mediated cytotoxicity in alkylating agent treated Saccharomyces cerevisiae.

Heacock M, Poltoratsky V, Prasad R, Wilson SH.

PLoS One. 2012;7(10):e47945. doi: 10.1371/journal.pone.0047945. Epub 2012 Oct 29.


Rapid profiling of disease alleles using a tunable reporter of protein misfolding.

Pittman AM, Lage MD, Poltoratsky V, Vrana JD, Paiardini A, Roncador A, Cellini B, Hughes RM, Tucker CL.

Genetics. 2012 Nov;192(3):831-42. doi: 10.1534/genetics.112.143750. Epub 2012 Aug 24.


Mutagenesis dependent upon the combination of activation-induced deaminase expression and a double-strand break.

Poltoratsky V, Heacock M, Kissling GE, Prasad R, Wilson SH.

Mol Immunol. 2010 Nov-Dec;48(1-3):164-70. doi: 10.1016/j.molimm.2010.08.013. Epub 2010 Sep 9.


Negligible impact of pol iota expression on the alkylation sensitivity of pol beta-deficient mouse fibroblast cells.

Poltoratsky V, Horton JK, Prasad R, Beard WA, Woodgate R, Wilson SH.

DNA Repair (Amst). 2008 Jun 1;7(6):830-3. doi: 10.1016/j.dnarep.2008.02.013. Epub 2008 Apr 22. No abstract available.


HMGB1 is a cofactor in mammalian base excision repair.

Prasad R, Liu Y, Deterding LJ, Poltoratsky VP, Kedar PS, Horton JK, Kanno S, Asagoshi K, Hou EW, Khodyreva SN, Lavrik OI, Tomer KB, Yasui A, Wilson SH.

Mol Cell. 2007 Sep 7;27(5):829-41.


Down-regulation of DNA polymerase beta accompanies somatic hypermutation in human BL2 cell lines.

Poltoratsky V, Prasad R, Horton JK, Wilson SH.

DNA Repair (Amst). 2007 Feb 4;6(2):244-53. Epub 2006 Nov 28.


DNA polymerase lambda protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/repair.

Braithwaite EK, Kedar PS, Lan L, Polosina YY, Asagoshi K, Poltoratsky VP, Horton JK, Miller H, Teebor GW, Yasui A, Wilson SH.

J Biol Chem. 2005 Sep 9;280(36):31641-7. Epub 2005 Jul 7.


REV1 mediated mutagenesis in base excision repair deficient mouse fibroblast.

Poltoratsky V, Horton JK, Prasad R, Wilson SH.

DNA Repair (Amst). 2005 Sep 28;4(10):1182-8.


Recombinogenic phenotype of human activation-induced cytosine deaminase.

Poltoratsky VP, Wilson SH, Kunkel TA, Pavlov YI.

J Immunol. 2004 Apr 1;172(7):4308-13.


Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line.

Zhang W, Bardwell PD, Woo CJ, Poltoratsky V, Scharff MD, Martin A.

Int Immunol. 2001 Sep;13(9):1175-84.


Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation.

Poltoratsky V, Woo CJ, Tippin B, Martin A, Goodman MF, Scharff MD.

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7976-81. Epub 2001 Jun 26.


Error-prone candidates vie for somatic mutation.

Poltoratsky V, Goodman MF, Scharff MD.

J Exp Med. 2000 Nov 20;192(10):F27-30. No abstract available.


Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex.

Barlev NA, Poltoratsky V, Owen-Hughes T, Ying C, Liu L, Workman JL, Berger SL.

Mol Cell Biol. 1998 Mar;18(3):1349-58.


The promotion of V region hypermutation.

Scharff MD, Poltoratsky V, Green NS.

J Exp Med. 1997 Jan 20;185(2):185-8. No abstract available.


Human DNA-activated protein kinase (DNA-PK) is homologous to phosphatidylinositol kinases.

Poltoratsky VP, Shi X, York JD, Lieber MR, Carter TH.

J Immunol. 1995 Nov 15;155(10):4529-33.


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