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Items: 1 to 50 of 187

1.

The application of human pluripotent stem cells to model the neuronal and glial components of neurodevelopmental disorders.

Lee KM, Hawi ZH, Parkington HC, Parish CL, Kumar PV, Polo JM, Bellgrove MA, Tong J.

Mol Psychiatry. 2019 Aug 27. doi: 10.1038/s41380-019-0495-0. [Epub ahead of print] Review.

PMID:
31455859
2.

Class-Switch Recombination Occurs Infrequently in Germinal Centers.

Roco JA, Mesin L, Binder SC, Nefzger C, Gonzalez-Figueroa P, Canete PF, Ellyard J, Shen Q, Robert PA, Cappello J, Vohra H, Zhang Y, Nowosad CR, Schiepers A, Corcoran LM, Toellner KM, Polo JM, Meyer-Hermann M, Victora GD, Vinuesa CG.

Immunity. 2019 Aug 20;51(2):337-350.e7. doi: 10.1016/j.immuni.2019.07.001. Epub 2019 Jul 30.

PMID:
31375460
3.

Correction to: Molecular Interaction Networks to Select Factors for Cell Conversion.

Ouyang JF, Kamaraj US, Polo JM, Gough J, Rackham OJL.

Methods Mol Biol. 2019;1975:C1. doi: 10.1007/978-1-4939-9224-9_20.

PMID:
31290135
4.

Molecular Interaction Networks to Select Factors for Cell Conversion.

Ouyang JF, Kamaraj US, Polo JM, Gough J, Rackham OJL.

Methods Mol Biol. 2019;1975:333-361. doi: 10.1007/978-1-4939-9224-9_16. Erratum in: Methods Mol Biol. 2019;1975:C1.

PMID:
31062318
5.

TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network.

Seruggia D, Oti M, Tripathi P, Canver MC, LeBlanc L, Di Giammartino DC, Bullen MJ, Nefzger CM, Sun YBY, Farouni R, Polo JM, Pinello L, Apostolou E, Kim J, Orkin SH, Das PP.

Mol Cell. 2019 Jun 20;74(6):1148-1163.e7. doi: 10.1016/j.molcel.2019.03.025. Epub 2019 Apr 17.

6.

Generation of Mouse-Induced Pluripotent Stem Cells by Lentiviral Transduction.

Liu X, Chen J, Firas J, Paynter JM, Nefzger CM, Polo JM.

Methods Mol Biol. 2019;1940:63-76. doi: 10.1007/978-1-4939-9086-3_5.

PMID:
30788818
7.

DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns.

Skvortsova K, Masle-Farquhar E, Luu PL, Song JZ, Qu W, Zotenko E, Gould CM, Du Q, Peters TJ, Colino-Sanguino Y, Pidsley R, Nair SS, Khoury A, Smith GC, Miosge LA, Reed JH, Kench JG, Rubin MA, Horvath L, Bogdanovic O, Lim SM, Polo JM, Goodnow CC, Stirzaker C, Clark SJ.

Cancer Cell. 2019 Feb 11;35(2):297-314.e8. doi: 10.1016/j.ccell.2019.01.004.

PMID:
30753827
8.

Generation of four iPSC lines from peripheral blood mononuclear cells (PBMCs) of an attention deficit hyperactivity disorder (ADHD) individual and a healthy sibling in an Australia-Caucasian family.

Tong J, Lee KM, Liu X, Nefzger CM, Vijayakumar P, Hawi Z, Pang KC, Parish CL, Polo JM, Bellgrove MA.

Stem Cell Res. 2019 Jan;34:101353. doi: 10.1016/j.scr.2018.11.014. Epub 2018 Dec 19.

9.

Let it RE:IN: integrating experimental observations to predict pluripotency network behaviour.

Rackham OJ, Polo JM.

EMBO J. 2019 Jan 3;38(1). pii: e101133. doi: 10.15252/embj.2018101133. Epub 2018 Dec 13. No abstract available.

PMID:
30545825
10.

Identification of dynamic undifferentiated cell states within the male germline.

La HM, Mäkelä JA, Chan AL, Rossello FJ, Nefzger CM, Legrand JMD, De Seram M, Polo JM, Hobbs RM.

Nat Commun. 2018 Jul 19;9(1):2819. doi: 10.1038/s41467-018-04827-z.

11.

A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs.

Pflueger C, Tan D, Swain T, Nguyen T, Pflueger J, Nefzger C, Polo JM, Ford E, Lister R.

Genome Res. 2018 Aug;28(8):1193-1206. doi: 10.1101/gr.233049.117. Epub 2018 Jun 15.

12.

SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program.

Ratnadiwakara M, Archer SK, Dent CI, Ruiz De Los Mozos I, Beilharz TH, Knaupp AS, Nefzger CM, Polo JM, Anko ML.

Elife. 2018 May 9;7. pii: e37419. doi: 10.7554/eLife.37419.

13.

TFAP2C regulates transcription in human naive pluripotency by opening enhancers.

Pastor WA, Liu W, Chen D, Ho J, Kim R, Hunt TJ, Lukianchikov A, Liu X, Polo JM, Jacobsen SE, Clark AT.

Nat Cell Biol. 2018 May;20(5):553-564. doi: 10.1038/s41556-018-0089-0. Epub 2018 Apr 25.

14.

Fine Tuning of Canonical Wnt Stimulation Enhances Differentiation of Pluripotent Stem Cells Independent of β-Catenin-Mediated T-Cell Factor Signaling.

Chen J, Nefzger CM, Rossello FJ, Sun YBY, Lim SM, Liu X, de Boer S, Knaupp AS, Li J, Davidson KC, Polo JM, Barberi T.

Stem Cells. 2018 Jun;36(6):822-833. doi: 10.1002/stem.2794. Epub 2018 Feb 14.

15.

Transient and Permanent Reconfiguration of Chromatin and Transcription Factor Occupancy Drive Reprogramming.

Knaupp AS, Buckberry S, Pflueger J, Lim SM, Ford E, Larcombe MR, Rossello FJ, de Mendoza A, Alaei S, Firas J, Holmes ML, Nair SS, Clark SJ, Nefzger CM, Lister R, Polo JM.

Cell Stem Cell. 2017 Dec 7;21(6):834-845.e6. doi: 10.1016/j.stem.2017.11.007.

16.

Cell Type of Origin Dictates the Route to Pluripotency.

Nefzger CM, Rossello FJ, Chen J, Liu X, Knaupp AS, Firas J, Paynter JM, Pflueger J, Buckberry S, Lim SM, Williams B, Alaei S, Faye-Chauhan K, Petretto E, Nilsson SK, Lister R, Ramialison M, Powell DR, Rackham OJL, Polo JM.

Cell Rep. 2017 Dec 5;21(10):2649-2660. doi: 10.1016/j.celrep.2017.11.029.

17.

Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.

Mariño E, Richards JL, McLeod KH, Stanley D, Yap YA, Knight J, McKenzie C, Kranich J, Oliveira AC, Rossello FJ, Krishnamurthy B, Nefzger CM, Macia L, Thorburn A, Baxter AG, Morahan G, Wong LH, Polo JM, Moore RJ, Lockett TJ, Clarke JM, Topping DL, Harrison LC, Mackay CR.

Nat Immunol. 2017 Oct 18;18(11):1271. doi: 10.1038/ni1117-1271c.

PMID:
29044240
18.

Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming.

Liu X, Nefzger CM, Rossello FJ, Chen J, Knaupp AS, Firas J, Ford E, Pflueger J, Paynter JM, Chy HS, O'Brien CM, Huang C, Mishra K, Hodgson-Garms M, Jansz N, Williams SM, Blewitt ME, Nilsson SK, Schittenhelm RB, Laslett AL, Lister R, Polo JM.

Nat Methods. 2017 Nov;14(11):1055-1062. doi: 10.1038/nmeth.4436. Epub 2017 Sep 25.

PMID:
28945704
19.

Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.

Mariño E, Richards JL, McLeod KH, Stanley D, Yap YA, Knight J, McKenzie C, Kranich J, Oliveira AC, Rossello FJ, Krishnamurthy B, Nefzger CM, Macia L, Thorburn A, Baxter AG, Morahan G, Wong LH, Polo JM, Moore RJ, Lockett TJ, Clarke JM, Topping DL, Harrison LC, Mackay CR.

Nat Immunol. 2017 Jul 19;18(8):951. doi: 10.1038/ni0817-951c. No abstract available.

PMID:
28722715
20.

Muscle Stem Cells Undergo Extensive Clonal Drift during Tissue Growth via Meox1-Mediated Induction of G2 Cell-Cycle Arrest.

Nguyen PD, Gurevich DB, Sonntag C, Hersey L, Alaei S, Nim HT, Siegel A, Hall TE, Rossello FJ, Boyd SE, Polo JM, Currie PD.

Cell Stem Cell. 2017 Jul 6;21(1):107-119.e6. doi: 10.1016/j.stem.2017.06.003.

21.

Towards understanding transcriptional networks in cellular reprogramming.

Firas J, Polo JM.

Curr Opin Genet Dev. 2017 Oct;46:1-8. doi: 10.1016/j.gde.2017.06.001. Epub 2017 Jun 21. Review.

PMID:
28646660
22.

DEAD-Box RNA Binding Protein DDX5: Not a Black-Box during Reprogramming.

Nefzger CM, Polo JM.

Cell Stem Cell. 2017 Apr 6;20(4):419-420. doi: 10.1016/j.stem.2017.03.006.

23.

Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.

Mariño E, Richards JL, McLeod KH, Stanley D, Yap YA, Knight J, McKenzie C, Kranich J, Oliveira AC, Rossello FJ, Krishnamurthy B, Nefzger CM, Macia L, Thorburn A, Baxter AG, Morahan G, Wong LH, Polo JM, Moore RJ, Lockett TJ, Clarke JM, Topping DL, Harrison LC, Mackay CR.

Nat Immunol. 2017 May;18(5):552-562. doi: 10.1038/ni.3713. Epub 2017 Mar 27. Erratum in: Nat Immunol. 2017 Jul 19;18(8):951. Erratum in: Nat Immunol. 2017 Oct 18;18(11):1271.

PMID:
28346408
24.

New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells.

O'Brien CM, Chy HS, Zhou Q, Blumenfeld S, Lambshead JW, Liu X, Kie J, Capaldo BD, Chung TL, Adams TE, Phan T, Bentley JD, McKinstry WJ, Oliva K, McMurrick PJ, Wang YC, Rossello FJ, Lindeman GJ, Chen D, Jarde T, Clark AT, Abud HE, Visvader JE, Nefzger CM, Polo JM, Loring JF, Laslett AL.

Stem Cells. 2017 Mar;35(3):626-640. doi: 10.1002/stem.2558. Epub 2017 Jan 19.

25.

Computational methods for direct cell conversion.

Kamaraj US, Gough J, Polo JM, Petretto E, Rackham OJ.

Cell Cycle. 2016 Dec 16;15(24):3343-3354. doi: 10.1080/15384101.2016.1238119. Epub 2016 Oct 13. Review.

26.

An improved reprogrammable mouse model harbouring the reverse tetracycline-controlled transcriptional transactivator 3.

Alaei S, Knaupp AS, Lim SM, Chen J, Holmes ML, Änkö ML, Nefzger CM, Polo JM.

Stem Cell Res. 2016 Jul;17(1):49-53. doi: 10.1016/j.scr.2016.05.008. Epub 2016 May 25.

27.

Amyotrophic Lateral Sclerosis in Northern Spain 40 Years Later: What Has Changed?

Riancho J, Lozano-Cuesta P, Santurtún A, Sánchez-Juan P, López-Vega JM, Berciano J, Polo JM.

Neurodegener Dis. 2016;16(5-6):337-41. doi: 10.1159/000445750. Epub 2016 May 19.

PMID:
27188850
28.

A Versatile Strategy for Isolating a Highly Enriched Population of Intestinal Stem Cells.

Nefzger CM, Jardé T, Rossello FJ, Horvay K, Knaupp AS, Powell DR, Chen J, Abud HE, Polo JM.

Stem Cell Reports. 2016 Mar 8;6(3):321-9. doi: 10.1016/j.stemcr.2016.01.014. Epub 2016 Feb 25.

29.

Subacute progressive aphasia: a rare presentation of Creutzfeldt-Jakob disease.

Riancho J, Delgado-Alvarado M, Fernández-Torre JL, Sánchez-Juan P, Polo JM.

J Neurol. 2016 Mar;263(3):600-2. doi: 10.1007/s00415-016-8054-y. Epub 2016 Feb 12. No abstract available.

PMID:
26872666
30.

Comparison of the patient and partner satisfaction with 700CX and Titan penile prostheses.

Otero JR, Cruz CR, Gómez BG, Geli JS, Polo JM, Castañé ER, Antolín AR.

Asian J Androl. 2017 May-Jun;19(3):321-325. doi: 10.4103/1008-682X.172822.

31.

Use of a lyophilized bovine pericardium graft to repair tunical defect in patients with Peyronie's disease: experience in a clinical setting.

Otero JR, Gómez BG, Polo JM, Mateo CP, Barreras SG, Cruz EG, de la Viña JR, Antolín AR.

Asian J Androl. 2017 May-Jun;19(3):316-320. doi: 10.4103/1008-682X.171572.

32.

A predictive computational framework for direct reprogramming between human cell types.

Rackham OJ, Firas J, Fang H, Oates ME, Holmes ML, Knaupp AS; FANTOM Consortium, Suzuki H, Nefzger CM, Daub CO, Shin JW, Petretto E, Forrest AR, Hayashizaki Y, Polo JM, Gough J.

Nat Genet. 2016 Mar;48(3):331-5. doi: 10.1038/ng.3487. Epub 2016 Jan 18.

PMID:
26780608
33.

Isolation of Reprogramming Intermediates During Generation of Induced Pluripotent Stem Cells from Mouse Embryonic Fibroblasts.

Nefzger CM, Alaei S, Polo JM.

Methods Mol Biol. 2015;1330:205-18. doi: 10.1007/978-1-4939-2848-4_17.

PMID:
26621600
34.

[Carotid-cavernous fistula successfully treated with carotid compression].

Riancho J, Navasa JM, Sedano-Tous MJ, Polo JM.

Med Clin (Barc). 2016 Jan 1;146(1):48. doi: 10.1016/j.medcli.2015.04.022. Epub 2015 Jun 3. Spanish. No abstract available.

PMID:
26048543
35.

Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium.

Horvay K, Jardé T, Casagranda F, Perreau VM, Haigh K, Nefzger CM, Akhtar R, Gridley T, Berx G, Haigh JJ, Barker N, Polo JM, Hime GR, Abud HE.

EMBO J. 2015 May 12;34(10):1319-35. doi: 10.15252/embj.201490881. Epub 2015 Mar 10.

36.

APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation.

Shu R, Wong W, Ma QH, Yang ZZ, Zhu H, Liu FJ, Wang P, Ma J, Yan S, Polo JM, Bernard CC, Stanton LW, Dawe GS, Xiao ZC.

Cell Death Dis. 2015 Feb 19;6:e1651. doi: 10.1038/cddis.2015.10.

37.

Transcription factor-mediated reprogramming: epigenetics and therapeutic potential.

Firas J, Liu X, Lim SM, Polo JM.

Immunol Cell Biol. 2015 Mar;93(3):284-9. doi: 10.1038/icb.2015.5. Epub 2015 Feb 3. Review.

PMID:
25643615
38.

Epigenetic memory in somatic cell nuclear transfer and induced pluripotency: evidence and implications.

Firas J, Liu X, Polo JM.

Differentiation. 2014 Jul;88(1):29-32. doi: 10.1016/j.diff.2014.09.001. Epub 2014 Oct 1.

PMID:
25281282
39.

Cell surface marker mediated purification of iPS cell intermediates from a reprogrammable mouse model.

Nefzger CM, Alaei S, Knaupp AS, Holmes ML, Polo JM.

J Vis Exp. 2014 Sep 6;(91):e51728. doi: 10.3791/51728.

40.

Haematopoietic stem cell induction by somite-derived endothelial cells controlled by meox1.

Nguyen PD, Hollway GE, Sonntag C, Miles LB, Hall TE, Berger S, Fernandez KJ, Gurevich DB, Cole NJ, Alaei S, Ramialison M, Sutherland RL, Polo JM, Lieschke GJ, Currie PD.

Nature. 2014 Aug 21;512(7514):314-8. doi: 10.1038/nature13678. Epub 2014 Aug 13.

PMID:
25119043
41.

GM-CSF and MEF-conditioned media support feeder-free reprogramming of mouse granulocytes to iPS cells.

Firas J, Liu X, Nefzger CM, Polo JM.

Differentiation. 2014 Jun;87(5):193-9. doi: 10.1016/j.diff.2014.05.003. Epub 2014 Jul 8.

PMID:
25015842
42.

Phases of reprogramming.

David L, Polo JM.

Stem Cell Res. 2014 May;12(3):754-61. doi: 10.1016/j.scr.2014.03.007. Epub 2014 Apr 1. Review.

43.

Reprogramming can be a transforming experience.

Hobbs RM, Polo JM.

Cell Stem Cell. 2014 Mar 6;14(3):269-71. doi: 10.1016/j.stem.2014.02.003.

44.

A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.

Hatzi K, Jiang Y, Huang C, Garrett-Bakelman F, Gearhart MD, Giannopoulou EG, Zumbo P, Kirouac K, Bhaskara S, Polo JM, Kormaksson M, MacKerell AD Jr, Xue F, Mason CE, Hiebert SW, Prive GG, Cerchietti L, Bardwell VJ, Elemento O, Melnick A.

Cell Rep. 2013 Aug 15;4(3):578-88. doi: 10.1016/j.celrep.2013.06.016. Epub 2013 Aug 1.

45.

Herpes simplex encephalitis: clinical presentation, neurological sequelae and new prognostic factors. Ten years of experience.

Riancho J, Delgado-Alvarado M, Sedano MJ, Polo JM, Berciano J.

Neurol Sci. 2013 Oct;34(10):1879-81. doi: 10.1007/s10072-013-1475-9. Epub 2013 Jun 19.

PMID:
23780666
46.

Nonanaplastic pleomorphic xanthoastrocytoma with meningeal dissemination presenting with bilateral visual loss.

Delgado-Alvarado M, Gómez-Román J, Sánchez-Salmón E, Rodríguez-Rodríguez E, Polo JM, García-Castaño A, Berciano J.

J Neuroimaging. 2014 Sep-Oct;24(5):533-5. doi: 10.1111/jon.12031. Epub 2013 May 23.

PMID:
23701304
47.

Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.

Apostolou E, Ferrari F, Walsh RM, Bar-Nur O, Stadtfeld M, Cheloufi S, Stuart HT, Polo JM, Ohsumi TK, Borowsky ML, Kharchenko PV, Park PJ, Hochedlinger K.

Cell Stem Cell. 2013 Jun 6;12(6):699-712. doi: 10.1016/j.stem.2013.04.013. Epub 2013 May 9.

48.

Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy.

Kaur G, Costa MW, Nefzger CM, Silva J, Fierro-González JC, Polo JM, Bell TD, Plachta N.

Nat Commun. 2013;4:1637. doi: 10.1038/ncomms2657.

PMID:
23535658
49.

Progressive multifocal leukoencephalopathy and idiopathic CD4 lymphocytopenia.

Delgado-Alvarado M, Sedano MJ, González-Quintanilla V, de Lucas EM, Polo JM, Berciano J.

J Neurol Sci. 2013 Apr 15;327(1-2):75-9. doi: 10.1016/j.jns.2013.02.002. Epub 2013 Mar 5. Review.

PMID:
23465508
50.

Muscle MRI in severe Guillain-Barré syndrome with motor nerve inexcitability.

Sedano MJ, Canga A, de Pablos C, Polo JM, Berciano J.

J Neurol. 2013 Jun;260(6):1624-30. doi: 10.1007/s00415-013-6845-y. Epub 2013 Jan 31.

PMID:
23370612

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