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Trends in the Use of Adjuvant Chemotherapy for High-Grade Truncal and Extremity Soft Tissue Sarcomas.

Squires MH, Ethun CG, Suarez-Kelly LP, Yu PY, Hughes TM, Shelby RD, Tran TB, Poultsides G, Charlson J, Gamblin TC, Tseng J, Roggin KK, Chouliaras K, Votanopoulos K, Krasnick BA, Fields RC, Pollock RE, Grignol V, Cardona K, Howard JH.

J Surg Res. 2020 Jan;245:577-586. doi: 10.1016/j.jss.2019.08.002. Epub 2019 Sep 5.


MDM2 Derived from Dedifferentiated Liposarcoma Extracellular Vesicles Induces MMP2 Production from Preadipocytes.

Casadei L, Calore F, Braggio DA, Zewdu A, Deshmukh AA, Fadda P, Lopez G, Wabitsch M, Song C, Leight JL, Grignol VP, Lev D, Croce CM, Pollock RE.

Cancer Res. 2019 Oct 1;79(19):4911-4922. doi: 10.1158/0008-5472.CAN-19-0203. Epub 2019 Aug 6.


Synchronous recurrence of concurrent colon adenocarcinoma and dedifferentiated liposarcoma.

Jung EE, Heinemann FS, Egelston CA, Wang J, Pollock RE, Lee PP, Tseng WW.

BMJ Case Rep. 2019 May 13;12(5). pii: e228868. doi: 10.1136/bcr-2018-228868.


Degree of MDM2 Amplification Affects Clinical Outcomes in Dedifferentiated Liposarcoma.

Bill KLJ, Seligson ND, Hays JL, Awasthi A, Demoret B, Stets CW, Duggan MC, Bupathi M, Brock GN, Millis SZ, Shakya R, Timmers CD, Wakely PE Jr, Pollock RE, Chen JL.

Oncologist. 2019 Jul;24(7):989-996. doi: 10.1634/theoncologist.2019-0047. Epub 2019 Apr 24.


Autophagy inhibition overcomes sorafenib resistance in S45F-mutated desmoid tumors.

Braggio D, Koller D, Jin F, Siva N, Zewdu A, Lopez G, Batte K, Casadei L, Welliver M, Strohecker AM, Lev D, Pollock RE.

Cancer. 2019 Aug 1;125(15):2693-2703. doi: 10.1002/cncr.32120. Epub 2019 Apr 12.


Multidisciplinary sarcoma care.

Pollock RE, Payne JE, Rogers AD, Smith SM, Iwenofu OH, Valerio IL, Zomerlei TA, Howard JH, Dornbos D 3rd, Galgano MA, Goulart C, Mendel E, Miller ED, Xu-Welliver M, Martin DD, Haglund KE, Bupathi M, Chen JL, Yeager ND.

Curr Probl Surg. 2018 Dec;55(12):517-580. doi: 10.1067/j.cpsurg.2018.10.006. Epub 2018 Nov 9. No abstract available.


Perioperative chemotherapy is not associated with improved survival in high-grade truncal sarcoma.

Yu PY, Beal EW, Hughes TM, Suarez-Kelly LP, Shelby RD, Ethun CG, Tran TB, Poultsides G, Charlson J, Gamblin TC, Tseng J, Roggin KK, Chouliaras K, Votanopoulos K, Krasnick BA, Fields RC, Pollock RE, Grignol V, Cardona K, Howard JH.

J Surg Res. 2018 Nov;231:248-256. doi: 10.1016/j.jss.2018.05.030. Epub 2018 Jun 23.


The TLR7/8/9 Antagonist IMO-8503 Inhibits Cancer-Induced Cachexia.

Calore F, Londhe P, Fadda P, Nigita G, Casadei L, Marceca GP, Fassan M, Lovat F, Gasparini P, Rizzotto L, Zanesi N, Jackson D, Mehta S, Nana-Sinkam P, Sampath D, Pollock RE, Guttridge DC, Croce CM.

Cancer Res. 2018 Dec 1;78(23):6680-6690. doi: 10.1158/0008-5472.CAN-17-3878. Epub 2018 Sep 12.


Surgical management of retroperitoneal sarcoma and opportunities for global collaboration.

Wang J, Grignol VP, Gronchi A, Luo CH, Pollock RE, Tseng WW.

Chin Clin Oncol. 2018 Aug;7(4):39. doi: 10.21037/cco.2018.07.05. Review.


Multidisciplinary management of soft tissue sarcoma.

Tseng WW, Luo CH, Pollock RE.

Chin Clin Oncol. 2018 Aug;7(4):34. doi: 10.21037/cco.2018.08.09. No abstract available.


miR-133a function in the pathogenesis of dedifferentiated liposarcoma.

Yu PY, Lopez G, Braggio D, Koller D, Bill KLJ, Prudner BC, Zewdu A, Chen JL, Iwenofu OH, Lev D, Strohecker AM, Fenger JM, Pollock RE, Guttridge DC.

Cancer Cell Int. 2018 Jun 26;18:89. doi: 10.1186/s12935-018-0583-2. eCollection 2018.


Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival.

Subbiah V, Lamhamedi-Cherradi SE, Cuglievan B, Menegaz BA, Camacho P, Huh W, Ramamoorthy V, Anderson PM, Pollock RE, Lev DC, Qiao W, McAleer MF, Benjamin RS, Patel S, Herzog CE, Daw NC, Feig BW, Lazar AJ, Hayes-Jordan A, Ludwig JA.

Clin Cancer Res. 2018 Oct 1;24(19):4865-4873. doi: 10.1158/1078-0432.CCR-18-0202. Epub 2018 Jun 5.


Second Primary Malignancies in Patients with Well-differentiated/Dedifferentiated Liposarcoma.

Jung E, Fiore M, Gronchi A, Grignol V, Pollock RE, Chong SS, Chopra S, Hamilton AS, Tseng WW.

Anticancer Res. 2018 Jun;38(6):3535-3542. doi: 10.21873/anticanres.12625.


Surgery for Abdominal Well-Differentiated Liposarcoma.

Mansfield SA, Pollock RE, Grignol VP.

Curr Treat Options Oncol. 2018 Jan 16;19(1):1. doi: 10.1007/s11864-018-0520-6. Review.


Historical perspectives and future directions in the surgical management of retroperitoneal sarcoma.

Tseng WW, Seo HJ, Pollock RE, Gronchi A.

J Surg Oncol. 2018 Jan;117(1):7-11. doi: 10.1002/jso.24888. Epub 2017 Nov 11. Review.


Retroperitoneal sarcomas: Big tumors that involve more than just "Getting it Out".

Tseng WW, Pollock RE, Gronchi A.

J Surg Oncol. 2018 Jan;117(1):5-6. doi: 10.1002/jso.24886. Epub 2017 Nov 11. No abstract available.


Clinicopathological variables of sporadic schwannomas of peripheral nerve in 291 patients and expression of biologically relevant markers.

Young ED, Ingram D, Metcalf-Doetsch W, Khan D, Al Sannaa G, Le Loarer F, Lazar AJF, Slopis J, Torres KE, Lev D, Pollock RE, McCutcheon IE.

J Neurosurg. 2018 Sep;129(3):805-814. doi: 10.3171/2017.2.JNS153004. Epub 2017 Sep 8. Erratum in: J Neurosurg. 2018 Sep 1;129(3):838.


Pulmonary tumor embolism secondary to soft tissue and bone sarcomas: a case report and literature review.

Latchana N, Daniel VC, Gould RW, Pollock RE.

World J Surg Oncol. 2017 Aug 30;15(1):168. doi: 10.1186/s12957-017-1223-3. Review.


Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression.

Casadei L, Calore F, Creighton CJ, Guescini M, Batte K, Iwenofu OH, Zewdu A, Braggio DA, Bill KL, Fadda P, Lovat F, Lopez G, Gasparini P, Chen JL, Kladney RD, Leone G, Lev D, Croce CM, Pollock RE.

Cancer Res. 2017 Jul 15;77(14):3846-3856. doi: 10.1158/0008-5472.CAN-16-2984. Epub 2017 Jun 6.


Postoperative Morbidity After Radical Resection of Primary Retroperitoneal Sarcoma: A Report From the Transatlantic RPS Working Group.

MacNeill AJ, Gronchi A, Miceli R, Bonvalot S, Swallow CJ, Hohenberger P, Van Coevorden F, Rutkowski P, Callegaro D, Hayes AJ, Honoré C, Fairweather M, Cannell A, Jakob J, Haas RL, Szacht M, Fiore M, Casali PG, Pollock RE, Barretta F, Raut CP, Strauss DC.

Ann Surg. 2018 May;267(5):959-964. doi: 10.1097/SLA.0000000000002250.


Autophagy as a potential target for sarcoma treatment.

Min L, Choy E, Pollock RE, Tu C, Hornicek F, Duan Z.

Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):40-50. doi: 10.1016/j.bbcan.2017.02.004. Epub 2017 Feb 24. Review.


Verticillin A Inhibits Leiomyosarcoma and Malignant Peripheral Nerve Sheath Tumor Growth via Induction of Apoptosis.

Zewdu A, Lopez G, Braggio D, Kenny C, Constantino D, Bid HK, Batte K, Iwenofu OH, Oberlies NH, Pearce CJ, Strohecker AM, Lev D, Pollock RE.

Clin Exp Pharmacol. 2016 Nov;6(6). pii: 221. doi: 10.4172/2161-1459.1000221. Epub 2016 Oct 24.


Post-relapse outcomes after primary extended resection of retroperitoneal sarcoma: A report from the Trans-Atlantic RPS Working Group.

MacNeill AJ, Miceli R, Strauss DC, Bonvalot S, Hohenberger P, Van Coevorden F, Rutkowski P, Callegaro D, Hayes AJ, Honoré C, Fairweather M, Cannell A, Jakob J, Haas RL, Szacht M, Fiore M, Casali PG, Pollock RE, Raut CP, Gronchi A, Swallow CJ.

Cancer. 2017 Jun 1;123(11):1971-1978. doi: 10.1002/cncr.30572. Epub 2017 Feb 2.


The Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG): "Red wine or white"?

Tseng WW, Pollock RE, Gronchi A.

Ann Surg Oncol. 2016 Dec;23(13):4418-4420. Epub 2016 Sep 9. No abstract available.


Evaluating the Effect of HDAC8 Inhibition in Malignant Peripheral Nerve Sheath Tumors.

Lopez G, Pollock RE.

Methods Mol Biol. 2017;1510:365-374.


Hypothesis: The Intratumoral Immune Response against a Cancer Progenitor Cell Impacts the Development of Well-Differentiated versus Dedifferentiated Disease in Liposarcoma.

Tseng WW, Chopra S, Engleman EG, Pollock RE.

Front Oncol. 2016 Jun 10;6:134. doi: 10.3389/fonc.2016.00134. eCollection 2016.


Patterns of major wound complications following multidisciplinary therapy for lower extremity soft tissue sarcoma.

Miller ED, Mo X, Andonian NT, Haglund KE, Martin DD, Liebner DA, Chen JL, Iwenofu OH, Chakravarti A, Scharschmidt TJ, Mayerson JL, Pollock RE, Xu-Welliver M.

J Surg Oncol. 2016 Sep;114(3):385-91. doi: 10.1002/jso.24313. Epub 2016 May 30.


Liposarcoma: molecular targets and therapeutic implications.

Bill KL, Casadei L, Prudner BC, Iwenofu H, Strohecker AM, Pollock RE.

Cell Mol Life Sci. 2016 Oct;73(19):3711-8. doi: 10.1007/s00018-016-2266-2. Epub 2016 May 12. Review.


Development and external validation of two nomograms to predict overall survival and occurrence of distant metastases in adults after surgical resection of localised soft-tissue sarcomas of the extremities: a retrospective analysis.

Callegaro D, Miceli R, Bonvalot S, Ferguson P, Strauss DC, Levy A, Griffin A, Hayes AJ, Stacchiotti S, Pechoux CL, Smith MJ, Fiore M, Dei Tos AP, Smith HG, Mariani L, Wunder JS, Pollock RE, Casali PG, Gronchi A.

Lancet Oncol. 2016 May;17(5):671-80. doi: 10.1016/S1470-2045(16)00010-3. Epub 2016 Apr 5.


NF-κB functions as a molecular link between tumor cells and Th1/Tc1 T cells in the tumor microenvironment to exert radiation-mediated tumor suppression.

Simon PS, Bardhan K, Chen MR, Paschall AV, Lu C, Bollag RJ, Kong FC, Jin J, Kong FM, Waller JL, Pollock RE, Liu K.

Oncotarget. 2016 Apr 26;7(17):23395-415. doi: 10.18632/oncotarget.8246.


External validation of a multi-institutional retroperitoneal sarcoma nomogram.

Raut CP, Miceli R, Strauss DC, Swallow CJ, Hohenberger P, van Coevorden F, Rutkowski P, Fiore M, Callegaro D, Casali PG, Haas RL, Hayes AJ, Honore C, Cannell AJ, Jakob J, Szacht M, Fairweather M, Pollock RE, Bonvalot S, Gronchi A.

Cancer. 2016 May 1;122(9):1417-24. doi: 10.1002/cncr.29931. Epub 2016 Feb 24.


Breast Cancer Genetic Counseling: A Surgeon's Perspective.

Agnese DM, Pollock RE.

Front Surg. 2016 Jan 28;3:4. doi: 10.3389/fsurg.2016.00004. eCollection 2016. Review.


An Overview of Chromatin-Regulating Proteins in Cells.

Zhang P, Torres K, Liu X, Liu CG, Pollock RE.

Curr Protein Pept Sci. 2016;17(5):401-10. Review.


Editorial (Thematic Issue: Chromatin Structure Regulating Proteins: Biology and Therapeutic Potential for Cancer).

Zhang P, Pollock RE.

Curr Protein Pept Sci. 2016;17(5):400. No abstract available.


Variability in Patterns of Recurrence After Resection of Primary Retroperitoneal Sarcoma (RPS): A Report on 1007 Patients From the Multi-institutional Collaborative RPS Working Group.

Gronchi A, Strauss DC, Miceli R, Bonvalot S, Swallow CJ, Hohenberger P, Van Coevorden F, Rutkowski P, Callegaro D, Hayes AJ, Honoré C, Fairweather M, Cannell A, Jakob J, Haas RL, Szacht M, Fiore M, Casali PG, Pollock RE, Raut CP.

Ann Surg. 2016 May;263(5):1002-9. doi: 10.1097/SLA.0000000000001447.


Intra-Abdominal and Abdominal Wall Desmoid Fibromatosis.

Howard JH, Pollock RE.

Oncol Ther. 2016;4(1):57-72. doi: 10.1007/s40487-016-0017-z. Epub 2016 Feb 3. Review.


Poly (ADP) ribose polymerase inhibition: A potential treatment of malignant peripheral nerve sheath tumor.

Kivlin CM, Watson KL, Al Sannaa GA, Belousov R, Ingram DR, Huang KL, May CD, Bolshakov S, Landers SM, Kalam AA, Slopis JM, McCutcheon IE, Pollock RE, Lev D, Lazar AJ, Torres KE.

Cancer Biol Ther. 2016;17(2):129-38. doi: 10.1080/15384047.2015.1108486. Epub 2015 Dec 9.


Clinical Observations and Molecular Variables of Primary Vascular Leiomyosarcoma.

Roland CL, Boland GM, Demicco EG, Lusby K, Ingram D, May CD, Kivlin CM, Watson K, Al Sannaa GA, Wang WL, Ravi V, Pollock RE, Lev D, Cormier JN, Hunt KK, Feig BW, Lazar AJ, Torres KE.

JAMA Surg. 2016 Apr;151(4):347-54. doi: 10.1001/jamasurg.2015.4205.


AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas.

May CD, Garnett J, Ma X, Landers SM, Ingram DR, Demicco EG, Al Sannaa GA, Vu T, Han L, Zhang Y, Kivlin CM, Bolshakov S, Kalam AA, Liu J, Zhou F, Broccoli D, Wang WL, Lazar AJ, Pollock RE, Lev D, Torres KE.

BMC Cancer. 2015 Nov 14;15:901. doi: 10.1186/s12885-015-1916-3.


SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma.

Bill KL, Garnett J, Meaux I, Ma X, Creighton CJ, Bolshakov S, Barriere C, Debussche L, Lazar AJ, Prudner BC, Casadei L, Braggio D, Lopez G, Zewdu A, Bid H, Lev D, Pollock RE.

Clin Cancer Res. 2016 Mar 1;22(5):1150-60. doi: 10.1158/1078-0432.CCR-15-1522. Epub 2015 Oct 16.


HDAC Inhibition for the Treatment of Epithelioid Sarcoma: Novel Cross Talk Between Epigenetic Components.

Lopez G, Song Y, Lam R, Ruder D, Creighton CJ, Bid HK, Bill KL, Bolshakov S, Zhang X, Lev D, Pollock RE.

Mol Cancer Res. 2016 Jan;14(1):35-43. doi: 10.1158/1541-7786.MCR-15-0295. Epub 2015 Sep 22.


Targeting the Notch pathway: A potential therapeutic approach for desmoid tumors.

Shang H, Braggio D, Lee YJ, Al Sannaa GA, Creighton CJ, Bolshakov S, Lazar AJ, Lev D, Pollock RE.

Cancer. 2015 Nov 15;121(22):4088-96. doi: 10.1002/cncr.29564. Epub 2015 Sep 8.


HDAC8, A Potential Therapeutic Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors (MPNST).

Lopez G, Bill KL, Bid HK, Braggio D, Constantino D, Prudner B, Zewdu A, Batte K, Lev D, Pollock RE.

PLoS One. 2015 Jul 22;10(7):e0133302. doi: 10.1371/journal.pone.0133302. eCollection 2015.


Phase 1 adaptive dose-finding study of neoadjuvant gemcitabine combined with radiation therapy for patients with high-risk extremity and trunk soft tissue sarcoma.

Tseng WW, Zhou S, To CA, Thall PF, Lazar AJ, Pollock RE, Lin PP, Cormier JN, Lewis VO, Feig BW, Hunt KK, Ballo MT, Patel S, Pisters PW.

Cancer. 2015 Oct 15;121(20):3659-67. doi: 10.1002/cncr.29544. Epub 2015 Jul 15.


Multicystic dedifferentiated retroperitoneal liposarcoma: tumour cyst fluid analysis and implications for management.

Khoury M, Sim GC, Harao M, Radvanyi L, Amini B, Benjamin RS, Pisters PW, Pollock RE, Tseng WW.

BMJ Case Rep. 2015 Jul 8;2015. pii: bcr2015211218. doi: 10.1136/bcr-2015-211218.


Angiosarcoma: A rare malignancy with protean clinical presentations.

Huntington JT, Jones C, Liebner DA, Chen JL, Pollock RE.

J Surg Oncol. 2015 Jun;111(8):941-50. doi: 10.1002/jso.23918. Epub 2015 May 28. Review.


The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma.

Bill KL, Garnett J, Ma X, May CD, Bolshakov S, Lazar AJ, Lev DC, Pollock RE.

Lab Invest. 2015 Aug;95(8):951-61. doi: 10.1038/labinvest.2015.62. Epub 2015 Jun 1.


Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway.

Zhang P, Yang X, Ma X, Ingram DR, Lazar AJ, Torres KE, Pollock RE.

Mol Cancer. 2015 Mar 7;14:55. doi: 10.1186/s12943-015-0325-1.


Contemporary approaches to sarcoma.

Kraybill WG, Pollock RE.

J Surg Oncol. 2015 Apr;111(5):489. doi: 10.1002/jso.23875. No abstract available.


Radiation-Associated Undifferentiated Pleomorphic Sarcoma is Associated with Worse Clinical Outcomes than Sporadic Lesions.

Dineen SP, Roland CL, Feig R, May C, Zhou S, Demicco E, Sannaa GA, Ingram D, Wang WL, Ravi V, Guadagnolo A, Lev D, Pollock RE, Hunt K, Cormier J, Lazar A, Feig B, Torres KE.

Ann Surg Oncol. 2015 Nov;22(12):3913-20. doi: 10.1245/s10434-015-4453-z. Epub 2015 Mar 6.

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