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Items: 8


Physiologically-based modeling of the pharmacokinetics of "catch-and-release" anti-carcinoembryonic antigen monoclonal antibodies in colorectal cancer xenograft mouse models.

Polli JR, Engler FA, Balthasar JP.

J Pharm Sci. 2018 Oct 12. pii: S0022-3549(18)30603-8. doi: 10.1016/j.xphs.2018.09.037. [Epub ahead of print]


"Catch-and-Release" Anti-Carcinoembryonic Antigen Monoclonal Antibody Leads to Greater Plasma and Tumor Exposure in a Mouse Model of Colorectal Cancer.

Engler FA, Polli JR, Li T, An B, Otteneder M, Qu J, Balthasar JP.

J Pharmacol Exp Ther. 2018 Jul;366(1):205-219. doi: 10.1124/jpet.117.246900. Epub 2018 May 7.


Triclosan Disrupts SKN-1/Nrf2-Mediated Oxidative Stress Response in C. elegans and Human Mesenchymal Stem Cells.

Yoon DS, Choi Y, Cha DS, Zhang P, Choi SM, Alfhili MA, Polli JR, Pendergrass D, Taki FA, Kapalavavi B, Pan X, Zhang B, Blackwell TK, Lee JW, Lee MH.

Sci Rep. 2017 Oct 3;7(1):12592. doi: 10.1038/s41598-017-12719-3.


From the Cover: ZnO Nanoparticles Enhanced Germ Cell Apoptosis in Caenorhabditis elegans, in Comparison with ZnCl2.

O'Donnell B, Huo L, Polli JR, Qiu L, Collier DN, Zhang B, Pan X.

Toxicol Sci. 2017 Apr 1;156(2):336-343. doi: 10.1093/toxsci/kfw258.


Drug-dependent behaviors and nicotinic acetylcholine receptor expressions in Caenorhabditis elegans following chronic nicotine exposure.

Polli JR, Dobbins DL, Kobet RA, Farwell MA, Zhang B, Lee MH, Pan X.

Neurotoxicology. 2015 Mar;47:27-36. doi: 10.1016/j.neuro.2014.12.005. Epub 2014 Dec 19.


Dispersed crude oil amplifies germ cell apoptosis in Caenorhabditis elegans, followed a CEP-1-dependent pathway.

Polli JR, Zhang Y, Pan X.

Arch Toxicol. 2014 Mar;88(3):543-51. doi: 10.1007/s00204-014-1198-6. Epub 2014 Feb 5.


Impacts of chronic low-level nicotine exposure on Caenorhabditis elegans reproduction: identification of novel gene targets.

Smith MA Jr, Zhang Y, Polli JR, Wu H, Zhang B, Xiao P, Farwell MA, Pan X.

Reprod Toxicol. 2013 Sep;40:69-75. doi: 10.1016/j.reprotox.2013.05.007. Epub 2013 Jun 2.


Chemical dispersant potentiates crude oil impacts on growth, reproduction, and gene expression in Caenorhabditis elegans.

Zhang Y, Chen D, Ennis AC, Polli JR, Xiao P, Zhang B, Stellwag EJ, Overton A, Pan X.

Arch Toxicol. 2013 Feb;87(2):371-82. doi: 10.1007/s00204-012-0936-x. Epub 2012 Sep 19.


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