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Items: 1 to 50 of 492

1.

Antibody-Dependent Natural Killer Cell Activation after Ebola Vaccination.

Wagstaffe HR, Clutterbuck EA, Bockstal V, Stoop JN, Luhn K, Douoguih M, Shukarev G, Snape MD, Pollard AJ, Riley EM, Goodier MR.

J Infect Dis. 2019 Dec 10. pii: jiz657. doi: 10.1093/infdis/jiz657. [Epub ahead of print]

PMID:
31821493
2.

Phase 3 Efficacy Analysis of a Typhoid Conjugate Vaccine Trial in Nepal.

Shakya M, Colin-Jones R, Theiss-Nyland K, Voysey M, Pant D, Smith N, Liu X, Tonks S, Mazur O, Farooq YG, Clarke J, Hill J, Adhikari A, Dongol S, Karkey A, Bajracharya B, Kelly S, Gurung M, Baker S, Neuzil KM, Shrestha S, Basnyat B, Pollard AJ; TyVAC Nepal Study Team.

N Engl J Med. 2019 Dec 5;381(23):2209-2218. doi: 10.1056/NEJMoa1905047.

3.

A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa.

Lo SW, Gladstone RA, van Tonder AJ, Du Plessis M, Cornick JE, Hawkins PA, Madhi SA, Nzenze SA, Kandasamy R, Ravikumar KL, Elmdaghri N, Kwambana-Adams B, Almeida SCG, Skoczynska A, Egorova E, Titov L, Saha SK, Paragi M, Everett DB, Antonio M, Klugman KP, Li Y, Metcalf BJ, Beall B, McGee L, Breiman RF, Bentley SD, von Gottberg A; Global Pneumococcal Sequencing Consortium .

J Antimicrob Chemother. 2019 Dec 2. pii: dkz477. doi: 10.1093/jac/dkz477. [Epub ahead of print]

PMID:
31789384
4.

IgA and IgG1 Specific to Vi Polysaccharide of Salmonella Typhi Correlate With Protection Status in a Typhoid Fever Controlled Human Infection Model.

Dahora LC, Jin C, Spreng RL, Feely F, Mathura R, Seaton KE, Zhang L, Hill J, Jones E, Alam SM, Dennison SM, Pollard AJ, Tomaras GD.

Front Immunol. 2019 Nov 1;10:2582. doi: 10.3389/fimmu.2019.02582. eCollection 2019.

5.

Plasma lipid profiles discriminate bacterial from viral infection in febrile children.

Wang X, Nijman R, Camuzeaux S, Sands C, Jackson H, Kaforou M, Emonts M, Herberg JA, Maconochie I, Carrol ED, Paulus SC, Zenz W, Van der Flier M, de Groot R, Martinon-Torres F, Schlapbach LJ, Pollard AJ, Fink C, Kuijpers TT, Anderson S, Lewis MR, Levin M, McClure M; EUCLIDS consortium.

Sci Rep. 2019 Nov 27;9(1):17714. doi: 10.1038/s41598-019-53721-1.

6.

Congenital viral infections in England over five decades: a population-based observational study.

Kadambari S, Pollard AJ, Goldacre MJ, Goldacre R.

Lancet Infect Dis. 2019 Nov 7. pii: S1473-3099(19)30416-5. doi: 10.1016/S1473-3099(19)30416-5. [Epub ahead of print]

PMID:
31708420
7.

UKMenCar4: A cross-sectional survey of asymptomatic meningococcal carriage amongst UK adolescents at a period of low invasive meningococcal disease incidence.

Bratcher HB, Rodrigues CMC, Finn A, Wootton M, Cameron JC, Smith A, Heath P, Ladhani S, Snape MD, Pollard AJ, Cunningham R, Borrow R, Trotter C, Gray SJ, Maiden MCJ, MacLennan JM.

Version 2. Wellcome Open Res. 2019 Oct 28 [revised 2019 Jan 1];4:118. doi: 10.12688/wellcomeopenres.15362.2. eCollection 2019.

8.

Persistent circulation of a fluoroquinolone-resistant Salmonella enterica Typhi clone in the Indian subcontinent.

Britto CD, Dyson ZA, Mathias S, Bosco A, Dougan G, Jose S, Nagaraj S, Holt KE, Pollard AJ.

J Antimicrob Chemother. 2019 Oct 26. pii: dkz435. doi: 10.1093/jac/dkz435. [Epub ahead of print]

PMID:
31665304
9.

Generating the Evidence for Typhoid Vaccine Introduction: Considerations for Global Disease Burden Estimates and Vaccine Testing Through Human Challenge.

Meiring JE, Giubilini A, Savulescu J, Pitzer VE, Pollard AJ.

Clin Infect Dis. 2019 Oct 15;69(Supplement_5):S402-S407. doi: 10.1093/cid/ciz630.

10.

Typhoid-From Past to Future.

Kirchhelle C, Pollard AJ, Vanderslott S.

Clin Infect Dis. 2019 Oct 15;69(Supplement_5):S375-S376. doi: 10.1093/cid/ciz551.

11.

Phylogenetic and geographic distribution of nickel hyperaccumulation in neotropical Psychotria.

McCartha GL, Taylor CM, van der Ent A, Echevarria G, Navarrete Gutiérrez DM, Pollard AJ.

Am J Bot. 2019 Oct;106(10):1377-1385. doi: 10.1002/ajb2.1362. Epub 2019 Sep 25.

PMID:
31553490
12.

Comparative transcriptomics between species attributes reactogenicity pathways induced by the capsular group B meningococcal vaccine, 4CMenB, to the membrane-bound endotoxin of its outer membrane vesicle component.

Sheerin D, O'Connor D, Dold C, Clutterbuck E, Attar M, Rollier CS, Sadarangani M, Pollard AJ.

Sci Rep. 2019 Sep 24;9(1):13797. doi: 10.1038/s41598-019-50310-0.

13.

Understanding parental perspectives on outcomes following paediatric encephalitis: A qualitative study.

Lemon J, Cooper J, Defres S, Easton A, Sadarangani M, Griffiths MJ, Pollard AJ, Solomon T, Kneen R.

PLoS One. 2019 Sep 16;14(9):e0220042. doi: 10.1371/journal.pone.0220042. eCollection 2019.

14.

Outcomes beyond hospital discharge in infants and children with viral meningitis: A systematic review.

Hudson JA, Broad J, Martin NG, Sadarangani M, Galal U, Kelly DF, Pollard AJ, Kadambari S.

Rev Med Virol. 2019 Sep 16:e2083. doi: 10.1002/rmv.2083. [Epub ahead of print] Review.

PMID:
31524309
15.

Diagnostic host gene signature for distinguishing enteric fever from other febrile diseases.

Blohmke CJ, Muller J, Gibani MM, Dobinson H, Shrestha S, Perinparajah S, Jin C, Hughes H, Blackwell L, Dongol S, Karkey A, Schreiber F, Pickard D, Basnyat B, Dougan G, Baker S, Pollard AJ, Darton TC.

EMBO Mol Med. 2019 Oct;11(10):e10431. doi: 10.15252/emmm.201910431. Epub 2019 Aug 30.

16.

Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leucocyte antigen locus.

Parks T, Elliott K, Lamagni T, Auckland K, Mentzer AJ, Guy R, Cartledge D, Strakova L, Connor DO, Pollard AJ, Neville MJ, Mahajan A, Ashrafian H, Chapman SJ, Hill AVS, Sriskandan S, Knight JC.

Genes Immun. 2019 Aug 29. doi: 10.1038/s41435-019-0082-z. [Epub ahead of print]

PMID:
31462703
17.

Bone and joint infections in Oxford: a 10-year retrospective review.

Abeywickrema M, Liu X, Kelly DF, Theologis T, Pollard AJ, Kadambari S.

Arch Dis Child. 2019 Aug 28. pii: archdischild-2019-317992. doi: 10.1136/archdischild-2019-317992. [Epub ahead of print] No abstract available.

PMID:
31462434
18.

The effect of H1N1 vaccination on serum miRNA expression in children: A tale of caution for microRNA microarray studies.

Drury RE, Pollard AJ, O'Connor D.

PLoS One. 2019 Aug 20;14(8):e0221143. doi: 10.1371/journal.pone.0221143. eCollection 2019.

19.

The effect of a single 4CMenB vaccine booster in young people more than ten years after infant immunisation: protocol of an exploratory immunogenicity study.

Davis K, Ford K, Craik R, Galal U, Rollier CS, Pollard AJ.

Trials. 2019 Jul 24;20(1):455. doi: 10.1186/s13063-019-3494-1.

20.

Author Correction: Airway response to respiratory syncytial virus has incidental antibacterial effects.

Sande CJ, Njunge JM, Ngoi JM, Mutunga MN, Chege T, Gicheru ET, Gardiner EM, Gwela A, Green CA, Drysdale SB, Berkley JA, Nokes DJ, Pollard AJ.

Nat Commun. 2019 Jul 18;10(1):3291. doi: 10.1038/s41467-019-11222-9.

21.

Two centuries of immunisation in the UK (part II).

Lang S, Loving S, McCarthy ND, Ramsay ME, Salisbury D, Pollard AJ.

Arch Dis Child. 2019 Jul 13. pii: archdischild-2019-317707. doi: 10.1136/archdischild-2019-317707. [Epub ahead of print]

PMID:
31302603
22.

Epigenetics in Sepsis: Understanding Its Role in Endothelial Dysfunction, Immunosuppression, and Potential Therapeutics.

Cross D, Drury R, Hill J, Pollard AJ.

Front Immunol. 2019 Jun 18;10:1363. doi: 10.3389/fimmu.2019.01363. eCollection 2019. Review.

23.

Two centuries of immunisation in the UK (part 1).

Lang S, Loving S, McCarthy ND, Ramsay ME, Salisbury D, Pollard AJ.

Arch Dis Child. 2019 Jul 4. pii: archdischild-2019-317314. doi: 10.1136/archdischild-2019-317314. [Epub ahead of print]

PMID:
31272966
24.

Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model.

Gibani MM, Jones E, Barton A, Jin C, Meek J, Camara S, Galal U, Heinz E, Rosenberg-Hasson Y, Obermoser G, Jones C, Campbell D, Black C, Thomaides-Brears H, Darlow C, Dold C, Silva-Reyes L, Blackwell L, Lara-Tejero M, Jiao X, Stack G, Blohmke CJ, Hill J, Angus B, Dougan G, Galán J, Pollard AJ.

Nat Med. 2019 Jul;25(7):1082-1088. doi: 10.1038/s41591-019-0505-4. Epub 2019 Jul 3.

25.

Classical and Non-classical Presentations of Complement Factor I Deficiency: Two Contrasting Cases Diagnosed via Genetic and Genomic Methods.

Shields AM, Pagnamenta AT, Pollard AJ; OxClinWGS, Taylor JC, Allroggen H, Patel SY.

Front Immunol. 2019 Jun 7;10:1150. doi: 10.3389/fimmu.2019.01150. eCollection 2019.

26.

A systematic review of antimicrobial resistance of typhoidal Salmonella in India.

Britto CD, John J, Verghese VP, Pollard AJ.

Indian J Med Res. 2019 Feb;149(2):151-163. doi: 10.4103/ijmr.IJMR_830_18. Review.

27.

Characterization and immunogenicity of a Shigella flexneri 2a O-antigen bioconjugate vaccine candidate.

Ravenscroft N, Braun M, Schneider J, Dreyer AM, Wetter M, Haeuptle MA, Kemmler S, Steffen M, Sirena D, Herwig S, Carranza P, Jones C, Pollard AJ, Wacker M, Kowarik M.

Glycobiology. 2019 Aug 20;29(9):669-680. doi: 10.1093/glycob/cwz044.

28.

Introduction.

Curtis N, Finn A, Warris A, Pollard AJ, van Rossum A, Ramilo O.

Pediatr Infect Dis J. 2019 Jun;38(6S Suppl 1):S1. doi: 10.1097/INF.0000000000002316. No abstract available.

PMID:
31205235
29.

Common Genetic Variations Associated with the Persistence of Immunity following Childhood Immunization.

O'Connor D, Png E, Khor CC, Snape MD, Hill AVS, van der Klis F, Hoggart C, Levin M, Hibberd ML, Pollard AJ.

Cell Rep. 2019 Jun 11;27(11):3241-3253.e4. doi: 10.1016/j.celrep.2019.05.053.

30.

OMIC Technologies and Vaccine Development: From the Identification of Vulnerable Individuals to the Formulation of Invulnerable Vaccines.

Cotugno N, Ruggiero A, Santilli V, Manno EC, Rocca S, Zicari S, Amodio D, Colucci M, Rossi P, Levy O, Martinon-Torres F, Pollard AJ, Palma P.

J Immunol Res. 2019 Apr 28;2019:8732191. doi: 10.1155/2019/8732191. eCollection 2019. Review.

31.

Cost-effectiveness of routine and campaign use of typhoid Vi-conjugate vaccine in Gavi-eligible countries: a modelling study.

Bilcke J, Antillón M, Pieters Z, Kuylen E, Abboud L, Neuzil KM, Pollard AJ, Paltiel AD, Pitzer VE.

Lancet Infect Dis. 2019 Jul;19(7):728-739. doi: 10.1016/S1473-3099(18)30804-1. Epub 2019 May 23.

32.

Airway response to respiratory syncytial virus has incidental antibacterial effects.

Sande CJ, Njunge JM, Mwongeli Ngoi J, Mutunga MN, Chege T, Gicheru ET, Gardiner EM, Gwela A, Green CA, Drysdale SB, Berkley JA, Nokes DJ, Pollard AJ.

Nat Commun. 2019 May 17;10(1):2218. doi: 10.1038/s41467-019-10222-z. Erratum in: Nat Commun. 2019 Jul 18;10(1):3291.

33.

Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study.

Osowicki J, Azzopardi KI, Baker C, Waddington CS, Pandey M, Schuster T, Grobler A, Cheng AC, Pollard AJ, McCarthy JS, Good MF, Walker MJ, Dale JB, Batzloff MR, Carapetis JR, Smeesters PR, Steer AC.

Vaccine. 2019 Jun 6;37(26):3485-3494. doi: 10.1016/j.vaccine.2019.03.059. Epub 2019 May 14.

PMID:
31101422
34.

Identification of regulatory variants associated with genetic susceptibility to meningococcal disease.

Borghini L, Png E, Binder A, Wright VJ, Pinnock E, de Groot R, Hazelzet J, Emonts M, Van der Flier M, Schlapbach LJ, Anderson S, Secka F, Salas A, Fink C, Carrol ED, Pollard AJ, Coin LJ, Kuijpers TW, Martinon-Torres F, Zenz W, Levin M, Hibberd ML, Davila S; EUCLIDS consortium.

Sci Rep. 2019 May 6;9(1):6966. doi: 10.1038/s41598-019-43292-6.

35.

Immunogenicity profiling of protein antigens from capsular group B Neisseria meningitidis.

Awanye AM, Chang CM, Wheeler JX, Chan H, Marsay L, Dold C, Rollier CS, Bird LE, Nettleship JE, Owens RJ, Pollard AJ, Derrick JP.

Sci Rep. 2019 May 2;9(1):6843. doi: 10.1038/s41598-019-43139-0.

36.

The role of immune correlates of protection on the pathway to licensure, policy decision and use of group B Streptococcus vaccines for maternal immunization: considerations from World Health Organization consultations.

Vekemans J, Crofts J, Baker CJ, Goldblatt D, Heath PT, Madhi SA, Le Doare K, Andrews N, Pollard AJ, Saha SK, Schrag SJ, Smith PG, Kaslow DC.

Vaccine. 2019 May 27;37(24):3190-3198. doi: 10.1016/j.vaccine.2019.04.039. Epub 2019 Apr 25. Review.

37.

Persistent circulation of vaccine serotypes and serotype replacement after five years of UK infant immunisation with PCV13.

Kandasamy R, Voysey M, Collins S, Berbers G, Robinson H, Noel I, Hughes H, Ndimah S, Gould K, Fry N, Sheppard C, Ladhani S, Snape MD, Hinds J, Pollard AJ.

J Infect Dis. 2019 Apr 20. pii: jiz178. doi: 10.1093/infdis/jiz178. [Epub ahead of print]

PMID:
31004136
38.

Nanoscale chemical imaging using tip-enhanced Raman spectroscopy.

Kumar N, Weckhuysen BM, Wain AJ, Pollard AJ.

Nat Protoc. 2019 Apr;14(4):1169-1193. doi: 10.1038/s41596-019-0132-z. Epub 2019 Mar 25.

PMID:
30911174
39.

X-Ray Fluorescence Ionomics of Herbarium Collections.

van der Ent A, Echevarria G, Pollard AJ, Erskine PD.

Sci Rep. 2019 Mar 18;9(1):4746. doi: 10.1038/s41598-019-40050-6.

40.

Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Napolitani G, Kurupati P, Teng KWW, Gibani MM, Rei M, Aulicino A, Preciado-Llanes L, Wong MT, Becht E, Howson L, de Haas P, Salio M, Blohmke CJ, Olsen LR, Pinto DMS, Scifo L, Jones C, Dobinson H, Campbell D, Juel HB, Thomaides-Brears H, Pickard D, Bumann D, Baker S, Dougan G, Simmons A, Gordon MA, Newell EW, Pollard AJ, Cerundolo V.

Nat Immunol. 2019 Apr;20(4):514. doi: 10.1038/s41590-019-0357-6.

PMID:
30862955
41.

Logistics of Implementing a Large-scale Typhoid Vaccine Trial in Kathmandu, Nepal.

Colin-Jones R, Shakya M, Voysey M, Theiss-Nyland K, Smith N, Pant D, Liu X, Tonks S, Mazur O, Farooq YG, Kelly S, Adhikari A, Dongol S, Karkey A, Shrestha S, Basnyat B, Pollard AJ.

Clin Infect Dis. 2019 Mar 7;68(Supplement_2):S138-S145. doi: 10.1093/cid/ciy1125.

42.

Assessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infection Among Bangladeshi Children: A Protocol for a Phase IIIb Trial.

Theiss-Nyland K, Qadri F, Colin-Jones R, Zaman K, Khanam F, Liu X, Voysey M, Khan A, Hasan N, Ashher F, Farooq YG, Pollard AJ, Clemens JD.

Clin Infect Dis. 2019 Mar 7;68(Supplement_2):S74-S82. doi: 10.1093/cid/ciy1107.

43.

Assessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infections Among Nepalese Children: A Protocol for a Phase III, Randomized Control Trial.

Theiss-Nyland K, Shakya M, Colin-Jones R, Voysey M, Smith N, Karkey A, Dongol S, Pant D, Farooq YG, Neuzil KM, Shrestha S, Basnyat B, Pollard AJ.

Clin Infect Dis. 2019 Mar 7;68(Supplement_2):S67-S73. doi: 10.1093/cid/ciy1106.

44.

Accelerating Typhoid Conjugate Vaccine Introduction: What Can Be Learned From Prior New Vaccine Introduction Initiatives?

Jamka LP, Simiyu KW, Bentsi-Enchill AD, Mwisongo AJ, Matzger H, Marfin AA, Pollard AJ, Neuzil KM.

Clin Infect Dis. 2019 Mar 7;68(Supplement_2):S171-S176. doi: 10.1093/cid/ciy1118.

45.

The Time is Now to Control Typhoid.

Pollard AJ, Marfin AA, Neuzil KM.

Clin Infect Dis. 2019 Mar 7;68(Supplement_2):S47-S49. doi: 10.1093/cid/ciy1115. No abstract available.

46.

The Design and Analysis of Seroefficacy Studies for Typhoid Conjugate Vaccines.

Liu X, Pitzer VE, Pollard AJ, Voysey M.

Clin Infect Dis. 2019 Mar 7;68(Supplement_2):S183-S190. doi: 10.1093/cid/ciy1119.

47.

Introduction of Typhoid Conjugate Vaccines in Africa and Asia.

Neuzil KM, Pollard AJ, Marfin AA.

Clin Infect Dis. 2019 Feb 15;68(Supplement_1):S27-S30. doi: 10.1093/cid/ciy878.

48.

Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults.

Green CA, Sande CJ, Scarselli E, Capone S, Vitelli A, Nicosia A, Silva-Reyes L, Thompson AJ, de Lara CM, Taylor KS, Haworth K, Hutchings CL, Cargill T, Angus B, Klenerman P, Pollard AJ.

J Infect. 2019 May;78(5):382-392. doi: 10.1016/j.jinf.2019.02.003. Epub 2019 Feb 8.

PMID:
30742894
49.

A Population-based Observational Study of Childhood Encephalitis in Children Admitted to Pediatric Intensive Care Units in England and Wales.

Iro MA, Sadarangani M, Nickless A, Kelly DF, Pollard AJ.

Pediatr Infect Dis J. 2019 Jul;38(7):673-677. doi: 10.1097/INF.0000000000002280.

PMID:
30640197
50.

Comparison of two schedules of two-dose priming with the ten-valent pneumococcal conjugate vaccine in Nepalese children: an open-label, randomised non-inferiority controlled trial.

Kandasamy R, Gurung M, Thorson S, Yu LM, Galal U, Voysey M, Kelly S, Wahl B, Berbers G, Finnegan K, Ansari I, Paudel K, Murdoch DR, O'Brien KL, Kelly DF, Goldblatt D, Shrestha S, Pollard AJ.

Lancet Infect Dis. 2019 Feb;19(2):156-164. doi: 10.1016/S1473-3099(18)30568-1. Epub 2019 Jan 8.

PMID:
30635252

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