Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 137

1.

APOL1-Associated Kidney Disease in Brazil.

Riella C, Siemens TA, Wang M, Campos RP, Moraes TP, Riella LV, Friedman DJ, Riella MC, Pollak MR.

Kidney Int Rep. 2019 Mar 20;4(7):923-929. doi: 10.1016/j.ekir.2019.03.006. eCollection 2019 Jul.

2.

Contributions of Rare Gene Variants to Familial and Sporadic FSGS.

Wang M, Chun J, Genovese G, Knob AU, Benjamin A, Wilkins MS, Friedman DJ, Appel GB, Lifton RP, Mane S, Pollak MR.

J Am Soc Nephrol. 2019 Jul 15. pii: ASN.2019020152. doi: 10.1681/ASN.2019020152. [Epub ahead of print]

PMID:
31308072
3.

Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity.

Chun J, Zhang JY, Wilkins MS, Subramanian B, Riella C, Magraner JM, Alper SL, Friedman DJ, Pollak MR.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3712-3721. doi: 10.1073/pnas.1820414116. Epub 2019 Feb 7.

PMID:
30733285
4.

The Glomerular Disease Study and Trial Consortium: A Grassroots Initiative to Foster Collaboration and Innovation.

Poyan Mehr A, Sadeghi-Najafabadi M, Chau K, Messmer J, Pai R, Roy N, Friedman D, Pollak MR, Schlondorff J, Naljayan M, Singh T, Lecker SH, Rodby R, Germain M, Rennke H, Stillman IE.

Kidney Int Rep. 2018 Sep 21;4(1):20-29. doi: 10.1016/j.ekir.2018.09.012. eCollection 2019 Jan. Review.

5.

Guided tissue organization and disease modeling in a kidney tubule array.

Subramanian B, Kaya O, Pollak MR, Yao G, Zhou J.

Biomaterials. 2018 Nov;183:295-305. doi: 10.1016/j.biomaterials.2018.07.059. Epub 2018 Aug 10.

PMID:
30189357
6.

Interrelated role of Klotho and calcium-sensing receptor in parathyroid hormone synthesis and parathyroid hyperplasia.

Fan Y, Liu W, Bi R, Densmore MJ, Sato T, Mannstadt M, Yuan Q, Zhou X, Olauson H, Larsson TE, Toka HR, Pollak MR, Brown EM, Lanske B.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3749-E3758. doi: 10.1073/pnas.1717754115. Epub 2018 Apr 4.

7.

UBD modifies APOL1-induced kidney disease risk.

Zhang JY, Wang M, Tian L, Genovese G, Yan P, Wilson JG, Thadhani R, Mottl AK, Appel GB, Bick AG, Sampson MG, Alper SL, Friedman DJ, Pollak MR.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3446-3451. doi: 10.1073/pnas.1716113115. Epub 2018 Mar 12.

8.

Disease-causing mutation in α-actinin-4 promotes podocyte detachment through maladaptation to periodic stretch.

Feng D, Notbohm J, Benjamin A, He S, Wang M, Ang LH, Bantawa M, Bouzid M, Del Gado E, Krishnan R, Pollak MR.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1517-1522. doi: 10.1073/pnas.1717870115. Epub 2018 Jan 29.

9.

Mechanical challenges and cytoskeletal impairments in focal segmental glomerulosclerosis.

Feng D, DuMontier C, Pollak MR.

Am J Physiol Renal Physiol. 2018 May 1;314(5):F921-F925. doi: 10.1152/ajprenal.00641.2017. Epub 2018 Jan 24.

10.

Introduction: APOL1-Associated Kidney Disease.

Pollak MR.

Semin Nephrol. 2017 Nov;37(6):489. doi: 10.1016/j.semnephrol.2017.07.001. No abstract available.

PMID:
29110755
11.

Apolipoprotein L1 Genetic Variants Are Associated with Chronic Kidney Disease but Not with Cardiovascular Disease in a Population Referred for Cardiac Catheterization.

Wang H, Pun PH, Kwee L, Craig D, Haynes C, Chryst-Ladd M, Svetkey LP, Patel UD, Hauser ER, Pollak MR, Kraus WE, Shah SH.

Cardiorenal Med. 2017 Feb;7(2):96-103. doi: 10.1159/000453458. Epub 2016 Dec 29.

12.

Parathyroid hormone controls paracellular Ca2+ transport in the thick ascending limb by regulating the tight-junction protein Claudin14.

Sato T, Courbebaisse M, Ide N, Fan Y, Hanai JI, Kaludjerovic J, Densmore MJ, Yuan Q, Toka HR, Pollak MR, Hou J, Lanske B.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3344-E3353. doi: 10.1073/pnas.1616733114. Epub 2017 Apr 3.

13.

A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy.

Skorecki KL, Lee JH, Langefeld CD, Rosset S, Tzur S, Wasser WG, Shemer R, Hawkins GA, Divers J, Parekh RS, Li M, Sampson MG, Kretzler M, Pollak MR, Shah S, Blackler D, Nichols B, Wilmot M, Alper SL, Freedman BI, Friedman DJ.

Nephrol Dial Transplant. 2018 Feb 1;33(2):323-330. doi: 10.1093/ndt/gfw451.

14.

Functional Validation of an Alpha-Actinin-4 Mutation as a Potential Cause of an Aggressive Presentation of Adolescent Focal Segmental Glomerulosclerosis: Implications for Genetic Testing.

Feng D, Steinke JM, Krishnan R, Birrane G, Pollak MR.

PLoS One. 2016 Dec 15;11(12):e0167467. doi: 10.1371/journal.pone.0167467. eCollection 2016.

15.

Most ApoL1 Is Secreted by the Liver.

Shukha K, Mueller JL, Chung RT, Curry MP, Friedman DJ, Pollak MR, Berg AH.

J Am Soc Nephrol. 2017 Apr;28(4):1079-1083. doi: 10.1681/ASN.2016040441. Epub 2016 Dec 8.

16.

Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injury.

Subramanian B, Sun H, Yan P, Charoonratana VT, Higgs HN, Wang F, Lai KV, Valenzuela DM, Brown EJ, Schlöndorff JS, Pollak MR.

Kidney Int. 2016 Aug;90(2):363-372. doi: 10.1016/j.kint.2016.04.020. Epub 2016 Jun 24.

17.

Non-muscle myosin-IIA is critical for podocyte f-actin organization, contractility, and attenuation of cell motility.

Bondzie PA, Chen HA, Cao MZ, Tomolonis JA, He F, Pollak MR, Henderson JM.

Cytoskeleton (Hoboken). 2016 Aug;73(8):377-95. doi: 10.1002/cm.21313. Epub 2016 Jul 21.

PMID:
27232264
18.

Apolipoprotein L1 and Kidney Disease in African Americans.

Friedman DJ, Pollak MR.

Trends Endocrinol Metab. 2016 Apr;27(4):204-215. doi: 10.1016/j.tem.2016.02.002. Epub 2016 Mar 3. Review.

19.

Structural characterization of the C-terminal coiled-coil domains of wild-type and kidney disease-associated mutants of apolipoprotein L1.

Sharma AK, Friedman DJ, Pollak MR, Alper SL.

FEBS J. 2016 May;283(10):1846-62. doi: 10.1111/febs.13706. Epub 2016 Apr 1.

20.

APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases.

Olabisi OA, Zhang JY, VerPlank L, Zahler N, DiBartolo S 3rd, Heneghan JF, Schlöndorff JS, Suh JH, Yan P, Alper SL, Friedman DJ, Pollak MR.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):830-7. doi: 10.1073/pnas.1522913113. Epub 2015 Dec 23.

21.

APOL1 Genotype, Kidney and Cardiovascular Disease, and Death in Older Adults.

Mukamal KJ, Tremaglio J, Friedman DJ, Ix JH, Kuller LH, Tracy RP, Pollak MR.

Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):398-403. doi: 10.1161/ATVBAHA.115.305970. Epub 2015 Dec 3.

22.

Effect Size Does Matter: The Long Road to Mechanistic Insight From Genome-Wide Association.

MacRae CA, Pollak MR.

Circulation. 2015 Nov 24;132(21):1943-5. doi: 10.1161/CIRCULATIONAHA.115.019306. Epub 2015 Oct 20. No abstract available.

PMID:
26487758
23.

The role of alpha-actinin-4 in human kidney disease.

Feng D, DuMontier C, Pollak MR.

Cell Biosci. 2015 Aug 18;5:44. doi: 10.1186/s13578-015-0036-8. eCollection 2015.

24.

Opportunities and Challenges of Genotyping Patients With Nephrotic Syndrome in the Genomic Era.

Sampson MG, Pollak MR.

Semin Nephrol. 2015 May;35(3):212-21. doi: 10.1016/j.semnephrol.2015.04.002. Review.

25.

Calcium Sensing in the Renal Tubule.

Toka HR, Pollak MR, Houillier P.

Physiology (Bethesda). 2015 Jul;30(4):317-26. doi: 10.1152/physiol.00042.2014. Review.

26.

BH3 domain-independent apolipoprotein L1 toxicity rescued by BCL2 prosurvival proteins.

Heneghan JF, Vandorpe DH, Shmukler BE, Giovinazzo JA, Raper J, Friedman DJ, Pollak MR, Alper SL.

Am J Physiol Cell Physiol. 2015 Sep 1;309(5):C332-47. doi: 10.1152/ajpcell.00142.2015. Epub 2015 Jun 24. Erratum in: Am J Physiol Cell Physiol. 2015 Dec 15;309(12):C856. Giovinnazo, J A [corrected to Giovinazzo, J A].

27.

Human Kidney Disease-causing INF2 Mutations Perturb Rho/Dia Signaling in the Glomerulus.

Sun H, Al-Romaih KI, MacRae CA, Pollak MR.

EBioMedicine. 2014 Nov 13;1(2-3):107-15. doi: 10.1016/j.ebiom.2014.11.009. eCollection 2014 Dec.

28.

Modifiers of Cardiac Phenotypes.

Pollak MR.

Circ Cardiovasc Genet. 2015 Jun;8(3):425-6. doi: 10.1161/CIRCGENETICS.115.001122. No abstract available.

PMID:
26082553
29.

Copy Number Variation at the APOL1 Locus.

Ruchi R, Genovese G, Lee J, Charoonratana VT, Bernhardy AJ, Alper SL, Kopp JB, Thadhani R, Friedman DJ, Pollak MR.

PLoS One. 2015 May 1;10(5):e0125410. doi: 10.1371/journal.pone.0125410. eCollection 2015.

30.

Alpha-actinin binding kinetics modulate cellular dynamics and force generation.

Ehrlicher AJ, Krishnan R, Guo M, Bidan CM, Weitz DA, Pollak MR.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):6619-24. doi: 10.1073/pnas.1505652112. Epub 2015 Apr 27.

31.

Idiopathic pediatric chronic kidney disease: can genomic technology crack the case?

Pollak MR.

J Clin Invest. 2015 May;125(5):1799-800. doi: 10.1172/JCI81509. Epub 2015 Apr 20.

32.

Clinical Features and Histology of Apolipoprotein L1-Associated Nephropathy in the FSGS Clinical Trial.

Kopp JB, Winkler CA, Zhao X, Radeva MK, Gassman JJ, D'Agati VD, Nast CC, Wei C, Reiser J, Guay-Woodford LM, Pollak MR, Hildebrandt F, Moxey-Mims M, Gipson DS, Trachtman H, Friedman AL, Kaskel FJ; FSGS-CT Study Consortium.

J Am Soc Nephrol. 2015 Jun;26(6):1443-8. doi: 10.1681/ASN.2013111242. Epub 2015 Jan 8.

33.

Familial FSGS.

Pollak MR.

Adv Chronic Kidney Dis. 2014 Sep;21(5):422-5. doi: 10.1053/j.ackd.2014.06.001. Review.

34.

Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1.

Nichols B, Jog P, Lee JH, Blackler D, Wilmot M, D'Agati V, Markowitz G, Kopp JB, Alper SL, Pollak MR, Friedman DJ.

Kidney Int. 2015 Feb;87(2):332-42. doi: 10.1038/ki.2014.270. Epub 2014 Aug 6.

35.

Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines.

Ma L, Shelness GS, Snipes JA, Murea M, Antinozzi PA, Cheng D, Saleem MA, Satchell SC, Banas B, Mathieson PW, Kretzler M, Hemal AK, Rudel LL, Petrovic S, Weckerle A, Pollak MR, Ross MD, Parks JS, Freedman BI.

J Am Soc Nephrol. 2015 Feb;26(2):339-48. doi: 10.1681/ASN.2013091017. Epub 2014 Jul 10.

36.

The role of the calcium-sensing receptor in disorders of abnormal calcium handling and cardiovascular disease.

Toka HR, Pollak MR.

Curr Opin Nephrol Hypertens. 2014 Sep;23(5):494-501. doi: 10.1097/MNH.0000000000000042. Review.

PMID:
24992569
37.

Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo.

Grgic I, Hofmeister AF, Genovese G, Bernhardy AJ, Sun H, Maarouf OH, Bijol V, Pollak MR, Humphreys BD.

Kidney Int. 2014 Dec;86(6):1116-29. doi: 10.1038/ki.2014.204. Epub 2014 Jun 18.

38.

The glomerulus: the sphere of influence.

Pollak MR, Quaggin SE, Hoenig MP, Dworkin LD.

Clin J Am Soc Nephrol. 2014 Aug 7;9(8):1461-9. doi: 10.2215/CJN.09400913. Epub 2014 May 29. Review.

39.

Evolution of the primate trypanolytic factor APOL1.

Thomson R, Genovese G, Canon C, Kovacsics D, Higgins MK, Carrington M, Winkler CA, Kopp J, Rotimi C, Adeyemo A, Doumatey A, Ayodo G, Alper SL, Pollak MR, Friedman DJ, Raper J.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2130-9. doi: 10.1073/pnas.1400699111. Epub 2014 May 7.

40.

Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS.

Gbadegesin RA, Hall G, Adeyemo A, Hanke N, Tossidou I, Burchette J, Wu G, Homstad A, Sparks MA, Gomez J, Jiang R, Alonso A, Lavin P, Conlon P, Korstanje R, Stander MC, Shamsan G, Barua M, Spurney R, Singhal PC, Kopp JB, Haller H, Howell D, Pollak MR, Shaw AS, Schiffer M, Winn MP.

J Am Soc Nephrol. 2014 Sep;25(9):1991-2002. doi: 10.1681/ASN.2013090976. Epub 2014 Mar 27.

41.

Mutations in PAX2 associate with adult-onset FSGS.

Barua M, Stellacci E, Stella L, Weins A, Genovese G, Muto V, Caputo V, Toka HR, Charoonratana VT, Tartaglia M, Pollak MR.

J Am Soc Nephrol. 2014 Sep;25(9):1942-53. doi: 10.1681/ASN.2013070686. Epub 2014 Mar 27.

42.

Genetic testing for nephrotic syndrome and FSGS in the era of next-generation sequencing.

Brown EJ, Pollak MR, Barua M.

Kidney Int. 2014 May;85(5):1030-8. doi: 10.1038/ki.2014.48. Epub 2014 Mar 5. Review.

43.

Increased burden of cardiovascular disease in carriers of APOL1 genetic variants.

Ito K, Bick AG, Flannick J, Friedman DJ, Genovese G, Parfenov MG, Depalma SR, Gupta N, Gabriel SB, Taylor HA Jr, Fox ER, Newton-Cheh C, Kathiresan S, Hirschhorn JN, Altshuler DM, Pollak MR, Wilson JG, Seidman JG, Seidman C.

Circ Res. 2014 Feb 28;114(5):845-50. doi: 10.1161/CIRCRESAHA.114.302347. Epub 2013 Dec 30.

44.

Plasma apolipoprotein L1 levels do not correlate with CKD.

Bruggeman LA, O'Toole JF, Ross MD, Madhavan SM, Smurzynski M, Wu K, Bosch RJ, Gupta S, Pollak MR, Sedor JR, Kalayjian RC.

J Am Soc Nephrol. 2014 Mar;25(3):634-44. doi: 10.1681/ASN.2013070700. Epub 2013 Nov 14.

45.

Health disparities in kidney disease--emerging data from the human genome.

Williams WW, Pollak MR.

N Engl J Med. 2013 Dec 5;369(23):2260-1. doi: 10.1056/NEJMe1312797. Epub 2013 Nov 9. No abstract available.

PMID:
24206461
46.

Exome sequencing and in vitro studies identified podocalyxin as a candidate gene for focal and segmental glomerulosclerosis.

Barua M, Shieh E, Schlondorff J, Genovese G, Kaplan BS, Pollak MR.

Kidney Int. 2014 Jan;85(1):124-33. doi: 10.1038/ki.2013.354. Epub 2013 Sep 18.

47.

Frequency of rare allelic variation in candidate genes among individuals with low and high urinary calcium excretion.

Toka HR, Genovese G, Mount DB, Pollak MR, Curhan GC.

PLoS One. 2013 Aug 26;8(8):e71885. doi: 10.1371/journal.pone.0071885. eCollection 2013.

48.

Pregnancy-associated polyuria in familial renal glycosuria.

Toka HR, Yang J, Zera CA, Duffield JS, Pollak MR, Mount DB.

Am J Kidney Dis. 2013 Dec;62(6):1160-4. doi: 10.1053/j.ajkd.2013.05.018. Epub 2013 Jul 18.

PMID:
23871407
49.

Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling.

Sun H, Schlondorff J, Higgs HN, Pollak MR.

J Am Soc Nephrol. 2013 May;24(6):917-29. doi: 10.1681/ASN.2012080834. Epub 2013 Apr 25.

50.

Parathyroid hormone ablation alters erythrocyte parameters that are rescued by calcium-sensing receptor gene deletion.

Romero JR, Youte R, Brown EM, Pollak MR, Goltzman D, Karaplis A, Pong LC, Chien L, Chattopadhyay N, Rivera A.

Eur J Haematol. 2013 Jul;91(1):37-45. doi: 10.1111/ejh.12110. Epub 2013 Apr 27.

Supplemental Content

Loading ...
Support Center