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Items: 1 to 50 of 737

1.

Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.

Lord SR, Collins JM, Cheng WC, Haider S, Wigfield S, Gaude E, Fielding BA, Pinnick KE, Harjes U, Segaran A, Jha P, Hoefler G, Pollak MN, Thompson AM, Roy PG, English R, Adams RF, Frezza C, Buffa FM, Karpe F, Harris AL.

Br J Cancer. 2019 Dec 10. doi: 10.1038/s41416-019-0665-5. [Epub ahead of print]

PMID:
31819193
2.

A Phase IIa Trial of Metformin for Colorectal Cancer Risk Reduction among Individuals with History of Colorectal Adenomas and Elevated Body Mass Index.

Zell JA, McLaren CE, Morgan TR, Lawson MJ, Rezk S, Albers CG, Chen WP, Carmichael JC, Chung J, Richmond E, Rodriguez LM, Szabo E, Ford LG, Pollak MN, Meyskens FL.

Cancer Prev Res (Phila). 2019 Dec 9. pii: canprevres.0262.2018. doi: 10.1158/1940-6207.CAPR-18-0262. [Epub ahead of print]

PMID:
31818851
3.

Study protocol of a phase II clinical trial of oral metformin for the intravesical treatment of non-muscle invasive bladder cancer.

Molenaar RJ, van Hattum JW, Brummelhuis IS, Oddens JR, Savci-Heijink CD, Boevé ER, van der Meer SA, Witjes JF, Pollak MN, de Reijke TM, Wilmink JW.

BMC Cancer. 2019 Nov 21;19(1):1133. doi: 10.1186/s12885-019-6346-1.

4.

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma.

Chan K, Robert F, Oertlin C, Kapeller-Libermann D, Avizonis D, Gutierrez J, Handly-Santana A, Doubrovin M, Park J, Schoepfer C, Da Silva B, Yao M, Gorton F, Shi J, Thomas CJ, Brown LE, Porco JA Jr, Pollak M, Larsson O, Pelletier J, Chio IIC.

Nat Commun. 2019 Nov 13;10(1):5151. doi: 10.1038/s41467-019-13086-5.

5.

APOL1 and Kidney Disease: From Genetics to Biology.

Friedman DJ, Pollak MR.

Annu Rev Physiol. 2019 Nov 11. doi: 10.1146/annurev-physiol-021119-034345. [Epub ahead of print]

PMID:
31710572
6.

Incidence of congenital thoracic malformations detected by prenatal ultrasound.

Pollak M, Gur M, Bronshtein M, Solt I, Masarweh K, Bentur L.

Pediatr Int. 2019 Nov 9. doi: 10.1111/ped.14048. [Epub ahead of print]

PMID:
31705721
7.

Focal segmental glomerulosclerosis ACTN4 mutants binding to actin: regulation by phosphomimetic mutations.

Shao H, Wingert B, Weins A, Pollak MR, Camacho C, Wells A.

Sci Rep. 2019 Oct 29;9(1):15517. doi: 10.1038/s41598-019-51825-2.

8.

Apolipoprotein L1 (APOL1) risk variant toxicity depends on the haplotype background.

Lannon H, Shah SS, Dias L, Blackler D, Alper SL, Pollak MR, Friedman DJ.

Kidney Int. 2019 Dec;96(6):1303-1307. doi: 10.1016/j.kint.2019.07.010. Epub 2019 Aug 1.

PMID:
31611067
9.

APOL1 gene variants and kidney disease in whites: the cardiovascular health study.

Drury ER, Friedman DJ, Pollak MR, Ix JH, Kuller LH, Tracy RP, Mukamal KJ.

Nephrol Dial Transplant. 2019 Dec 1;34(12):2155-2156. doi: 10.1093/ndt/gfz186. No abstract available.

PMID:
31580460
10.

APOL1 Kidney Risk Variants Induce Cell Death via Mitochondrial Translocation and Opening of the Mitochondrial Permeability Transition Pore.

Shah SS, Lannon H, Dias L, Zhang JY, Alper SL, Pollak MR, Friedman DJ.

J Am Soc Nephrol. 2019 Dec;30(12):2355-2368. doi: 10.1681/ASN.2019020114. Epub 2019 Sep 26.

PMID:
31558683
11.

Metastatic Breast Carcinoma-Associated Fibroblasts Have Enhanced Protumorigenic Properties Related to Increased IGF2 Expression.

Gui Y, Aguilar-Mahecha A, Krzemien U, Hosein A, Buchanan M, Lafleur J, Pollak M, Ferrario C, Basik M.

Clin Cancer Res. 2019 Dec 1;25(23):7229-7242. doi: 10.1158/1078-0432.CCR-19-1268. Epub 2019 Sep 12.

PMID:
31515454
12.

Total physical activity but not diet quality associated with postnatal depressive symptoms amongst women living in socioeconomically disadvantaged neighborhoods.

Pollak MJ, Milte CM, van der Pligt P, Teychenne M.

Nutr Res. 2019 Aug;68:54-61. doi: 10.1016/j.nutres.2019.05.009. Epub 2019 Jun 24.

PMID:
31421393
13.

Autosomal Recessive Alport Syndrome Unveiled by Pregnancy.

Drury ER, Stillman IE, Pollak MR, Denker BM.

Nephron. 2019;143(4):288-292. doi: 10.1159/000502147. Epub 2019 Aug 13.

PMID:
31408864
14.

Relationship of circulating insulin-like growth factor-I and binding proteins 1-7 with mammographic density among women undergoing image-guided diagnostic breast biopsy.

Hada M, Oh H, Pfeiffer RM, Falk RT, Fan S, Mullooly M, Pollak M, Geller B, Vacek PM, Weaver D, Shepherd J, Wang J, Fan B, Mahmoudzadeh AP, Malkov S, Herschorn S, Brinton LA, Sherman ME, Gierach GL.

Breast Cancer Res. 2019 Jul 23;21(1):81. doi: 10.1186/s13058-019-1162-8.

15.

APOL1-Associated Kidney Disease in Brazil.

Riella C, Siemens TA, Wang M, Campos RP, Moraes TP, Riella LV, Friedman DJ, Riella MC, Pollak MR.

Kidney Int Rep. 2019 Mar 20;4(7):923-929. doi: 10.1016/j.ekir.2019.03.006. eCollection 2019 Jul.

16.

mTOR as a central regulator of lifespan and aging.

Papadopoli D, Boulay K, Kazak L, Pollak M, Mallette F, Topisirovic I, Hulea L.

F1000Res. 2019 Jul 2;8. pii: F1000 Faculty Rev-998. doi: 10.12688/f1000research.17196.1. eCollection 2019. Review.

17.

Contributions of Rare Gene Variants to Familial and Sporadic FSGS.

Wang M, Chun J, Genovese G, Knob AU, Benjamin A, Wilkins MS, Friedman DJ, Appel GB, Lifton RP, Mane S, Pollak MR.

J Am Soc Nephrol. 2019 Sep;30(9):1625-1640. doi: 10.1681/ASN.2019020152. Epub 2019 Jul 15.

PMID:
31308072
18.

High-Fat Diet Accelerates Carcinogenesis in a Mouse Model of Barrett's Esophagus via Interleukin 8 and Alterations to the Gut Microbiome.

Münch NS, Fang HY, Ingermann J, Maurer HC, Anand A, Kellner V, Sahm V, Wiethaler M, Baumeister T, Wein F, Einwächter H, Bolze F, Klingenspor M, Haller D, Kavanagh M, Lysaght J, Friedman R, Dannenberg AJ, Pollak M, Holt PR, Muthupalani S, Fox JG, Whary MT, Lee Y, Ren TY, Elliot R, Fitzgerald R, Steiger K, Schmid RM, Wang TC, Quante M.

Gastroenterology. 2019 Aug;157(2):492-506.e2. doi: 10.1053/j.gastro.2019.04.013. Epub 2019 Apr 15.

PMID:
30998992
19.

A Distributed Architecture for Human-Drone Teaming: Timing Challenges and Interaction Opportunities.

Hummel KA, Pollak M, Krahofer J.

Sensors (Basel). 2019 Mar 20;19(6). pii: E1379. doi: 10.3390/s19061379.

20.

The associations of anthropometric, behavioural and sociodemographic factors with circulating concentrations of IGF-I, IGF-II, IGFBP-1, IGFBP-2 and IGFBP-3 in a pooled analysis of 16,024 men from 22 studies.

Watts EL, Perez-Cornago A, Appleby PN, Albanes D, Ardanaz E, Black A, Bueno-de-Mesquita HB, Chan JM, Chen C, Chubb SAP, Cook MB, Deschasaux M, Donovan JL, English DR, Flicker L, Freedman ND, Galan P, Giles GG, Giovannucci EL, Gunter MJ, Habel LA, Häggström C, Haiman C, Hamdy FC, Hercberg S, Holly JM, Huang J, Huang WY, Johansson M, Kaaks R, Kubo T, Lane JA, Layne TM, Le Marchand L, Martin RM, Metter EJ, Mikami K, Milne RL, Morris HA, Mucci LA, Neal DE, Neuhouser ML, Oliver SE, Overvad K, Ozasa K, Pala V, Pernar CH, Pollak M, Rowlands MA, Schaefer CA, Schenk JM, Stattin P, Tamakoshi A, Thysell E, Touvier M, Trichopoulou A, Tsilidis KK, Van Den Eeden SK, Weinstein SJ, Wilkens L, Yeap BB, Key TJ, Allen NE, Travis RC.

Int J Cancer. 2019 Dec 15;145(12):3244-3256. doi: 10.1002/ijc.32276. Epub 2019 Apr 4.

21.

Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity.

Chun J, Zhang JY, Wilkins MS, Subramanian B, Riella C, Magraner JM, Alper SL, Friedman DJ, Pollak MR.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3712-3721. doi: 10.1073/pnas.1820414116. Epub 2019 Feb 7.

22.

Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion.

Heitzeneder S, Sotillo E, Shern JF, Sindiri S, Xu P, Jones R, Pollak M, Noer PR, Lorette J, Fazli L, Alag A, Meltzer P, Lau C, Conover CA, Oxvig C, Sorensen PH, Maris JM, Khan J, Mackall CL.

J Natl Cancer Inst. 2019 Sep 1;111(9):970-982. doi: 10.1093/jnci/djy209.

PMID:
30698726
23.

Impact of Addition of Metformin to Abiraterone in Metastatic Castration-Resistant Prostate Cancer Patients With Disease Progressing While Receiving Abiraterone Treatment (MetAb-Pro): Phase 2 Pilot Study.

Mark M, Klingbiel D, Mey U, Winterhalder R, Rothermundt C, Gillessen S, von Moos R, Pollak M, Manetsch G, Strebel R, Cathomas R.

Clin Genitourin Cancer. 2019 Apr;17(2):e323-e328. doi: 10.1016/j.clgc.2018.12.009. Epub 2019 Jan 2.

PMID:
30686756
24.

The Glomerular Disease Study and Trial Consortium: A Grassroots Initiative to Foster Collaboration and Innovation.

Poyan Mehr A, Sadeghi-Najafabadi M, Chau K, Messmer J, Pai R, Roy N, Friedman D, Pollak MR, Schlondorff J, Naljayan M, Singh T, Lecker SH, Rodby R, Germain M, Rennke H, Stillman IE.

Kidney Int Rep. 2018 Sep 21;4(1):20-29. doi: 10.1016/j.ekir.2018.09.012. eCollection 2019 Jan. Review.

25.

Cancer Prevention: A Message from the New Editors-in-Chief.

DuBois RN, Pollak MN.

Cancer Prev Res (Phila). 2019 Jan;12(1):1-2. doi: 10.1158/1940-6207.CAPR-18-0349. Epub 2018 Dec 27. No abstract available.

PMID:
30591430
26.

Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer.

Lord SR, Cheng WC, Liu D, Gaude E, Haider S, Metcalf T, Patel N, Teoh EJ, Gleeson F, Bradley K, Wigfield S, Zois C, McGowan DR, Ah-See ML, Thompson AM, Sharma A, Bidaut L, Pollak M, Roy PG, Karpe F, James T, English R, Adams RF, Campo L, Ayers L, Snell C, Roxanis I, Frezza C, Fenwick JD, Buffa FM, Harris AL.

Cell Metab. 2018 Nov 6;28(5):679-688.e4. doi: 10.1016/j.cmet.2018.08.021. Epub 2018 Sep 20.

27.

Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides.

Hulea L, Gravel SP, Morita M, Cargnello M, Uchenunu O, Im YK, Lehuédé C, Ma EH, Leibovitch M, McLaughlan S, Blouin MJ, Parisotto M, Papavasiliou V, Lavoie C, Larsson O, Ohh M, Ferreira T, Greenwood C, Bridon G, Avizonis D, Ferbeyre G, Siegel P, Jones RG, Muller W, Ursini-Siegel J, St-Pierre J, Pollak M, Topisirovic I.

Cell Metab. 2018 Dec 4;28(6):817-832.e8. doi: 10.1016/j.cmet.2018.09.001. Epub 2018 Sep 20.

28.

Guided tissue organization and disease modeling in a kidney tubule array.

Subramanian B, Kaya O, Pollak MR, Yao G, Zhou J.

Biomaterials. 2018 Nov;183:295-305. doi: 10.1016/j.biomaterials.2018.07.059. Epub 2018 Aug 10.

29.

Expression of IGF/insulin receptor in prostate cancer tissue and progression to lethal disease.

Ahearn TU, Peisch S, Pettersson A, Ebot EM, Zhou CK, Graff RE, Sinnott JA, Fazli L, Judson GL, Bismar TA, Rider JR, Gerke T, Chan JM, Fiorentino M, Flavin R, Sesso HD, Finn S, Giovannucci EL, Gleave M, Loda M, Li Z, Pollak M, Mucci LA; Transdisciplinary Prostate Cancer Partnership (ToPCaP).

Carcinogenesis. 2018 Dec 31;39(12):1431-1437. doi: 10.1093/carcin/bgy112.

PMID:
30165429
30.

A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup.

Justice JN, Ferrucci L, Newman AB, Aroda VR, Bahnson JL, Divers J, Espeland MA, Marcovina S, Pollak MN, Kritchevsky SB, Barzilai N, Kuchel GA.

Geroscience. 2018 Dec;40(5-6):419-436. doi: 10.1007/s11357-018-0042-y. Epub 2018 Aug 27. Review.

31.

Diet boosts the effectiveness of a cancer drug.

Pollak M.

Nature. 2018 Aug;560(7719):439-440. doi: 10.1038/d41586-018-05871-x. No abstract available.

PMID:
30127476
32.

Simultaneous Extraction of RNA and Metabolites from Single Kidney Tissue Specimens for Combined Transcriptomic and Metabolomic Profiling.

Leuthold P, Schwab M, Hofmann U, Winter S, Rausch S, Pollak MN, Hennenlotter J, Bedke J, Schaeffeler E, Haag M.

J Proteome Res. 2018 Sep 7;17(9):3039-3049. doi: 10.1021/acs.jproteome.8b00199. Epub 2018 Aug 23.

PMID:
30091608
33.

Oncogenic kinases and perturbations in protein synthesis machinery and energetics in neoplasia.

Uchenunu O, Pollak M, Topisirovic I, Hulea L.

J Mol Endocrinol. 2019 Feb 1;62(2):R83-R103. doi: 10.1530/JME-18-0058. Review.

34.

Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer.

Wang Y, Nasiri AR, Damsky WE, Perry CJ, Zhang XM, Rabin-Court A, Pollak MN, Shulman GI, Perry RJ.

Cell Rep. 2018 Jul 3;24(1):47-55. doi: 10.1016/j.celrep.2018.06.008.

35.

Association of APOL1 With Heart Failure With Preserved Ejection Fraction in Postmenopausal African American Women.

Franceschini N, Kopp JB, Barac A, Martin LW, Li Y, Qian H, Reiner AP, Pollak M, Wallace RB, Rosamond WD, Winkler CA.

JAMA Cardiol. 2018 Aug 1;3(8):712-720. doi: 10.1001/jamacardio.2018.1827.

36.

Interplay between ShcA Signaling and PGC-1α Triggers Targetable Metabolic Vulnerabilities in Breast Cancer.

Im YK, Najyb O, Gravel SP, McGuirk S, Ahn R, Avizonis DZ, Chénard V, Sabourin V, Hudson J, Pawson T, Topisirovic I, Pollak M, St-Pierre J, Ursini-Siegel J.

Cancer Res. 2018 Sep 1;78(17):4826-4838. doi: 10.1158/0008-5472.CAN-17-3696. Epub 2018 Jun 21.

37.

Insulin-like growth factor 1 receptor stabilizes the ETV6-NTRK3 chimeric oncoprotein by blocking its KPC1/Rnf123-mediated proteasomal degradation.

Tognon CE, Rafn B, Cetinbas NM, Kamura T, Trigo G, Rotblat B, Okumura F, Matsumoto M, Chow C, Davare M, Pollak M, Mayor T, Sorensen PH.

J Biol Chem. 2018 Aug 10;293(32):12502-12515. doi: 10.1074/jbc.RA117.000321. Epub 2018 Jun 14.

38.

Early prenatal ultrasound diagnosis of congenital thoracic malformations.

Bentur L, Gur M, Pollak M, Masarweh K, Solt I, Bronshtein M.

J Matern Fetal Neonatal Med. 2019 Nov;32(21):3531-3536. doi: 10.1080/14767058.2018.1465920. Epub 2018 May 2.

PMID:
29720002
39.

Interrelated role of Klotho and calcium-sensing receptor in parathyroid hormone synthesis and parathyroid hyperplasia.

Fan Y, Liu W, Bi R, Densmore MJ, Sato T, Mannstadt M, Yuan Q, Zhou X, Olauson H, Larsson TE, Toka HR, Pollak MR, Brown EM, Lanske B.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3749-E3758. doi: 10.1073/pnas.1717754115. Epub 2018 Apr 4.

40.

UBD modifies APOL1-induced kidney disease risk.

Zhang JY, Wang M, Tian L, Genovese G, Yan P, Wilson JG, Thadhani R, Mottl AK, Appel GB, Bick AG, Sampson MG, Alper SL, Friedman DJ, Pollak MR.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3446-3451. doi: 10.1073/pnas.1716113115. Epub 2018 Mar 12.

41.

Serum insulin-like growth factor (IGF)-I and IGF binding protein-3 in relation to terminal duct lobular unit involution of the normal breast in Caucasian and African American women: The Susan G. Komen Tissue Bank.

Oh H, Pfeiffer RM, Falk RT, Horne HN, Xiang J, Pollak M, Brinton LA, Storniolo AMV, Sherman ME, Gierach GL, Figueroa JD.

Int J Cancer. 2018 Aug 1;143(3):496-507. doi: 10.1002/ijc.31333. Epub 2018 Apr 1.

42.

On dynamical properties of electrons in Anderson-Mott insulators.

Pollak M.

J Phys Condens Matter. 2018 Mar 14;30(10):105602. doi: 10.1088/1361-648X/aaac94.

PMID:
29393067
43.

Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults.

Kulkarni AS, Brutsaert EF, Anghel V, Zhang K, Bloomgarden N, Pollak M, Mar JC, Hawkins M, Crandall JP, Barzilai N.

Aging Cell. 2018 Apr;17(2). doi: 10.1111/acel.12723. Epub 2018 Jan 31.

44.

Disease-causing mutation in α-actinin-4 promotes podocyte detachment through maladaptation to periodic stretch.

Feng D, Notbohm J, Benjamin A, He S, Wang M, Ang LH, Bantawa M, Bouzid M, Del Gado E, Krishnan R, Pollak MR.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1517-1522. doi: 10.1073/pnas.1717870115. Epub 2018 Jan 29.

45.

Mechanical challenges and cytoskeletal impairments in focal segmental glomerulosclerosis.

Feng D, DuMontier C, Pollak MR.

Am J Physiol Renal Physiol. 2018 May 1;314(5):F921-F925. doi: 10.1152/ajprenal.00641.2017. Epub 2018 Jan 24. Review.

46.

Incretin-based Drugs and the Incidence of Colorectal Cancer in Patients with Type 2 Diabetes.

Abrahami D, Yin H, Yu OHY, Pollak MN, Azoulay L.

Epidemiology. 2018 Mar;29(2):246-253. doi: 10.1097/EDE.0000000000000793.

PMID:
29283894
47.

Effects of Rapid Weight Loss on Systemic and Adipose Tissue Inflammation and Metabolism in Obese Postmenopausal Women.

Alemán JO, Iyengar NM, Walker JM, Milne GL, Da Rosa JC, Liang Y, Giri DD, Zhou XK, Pollak MN, Hudis CA, Breslow JL, Holt PR, Dannenberg AJ.

J Endocr Soc. 2017 Apr 25;1(6):625-637. doi: 10.1210/js.2017-00020. eCollection 2017 Jun 1.

48.

Introduction: APOL1-Associated Kidney Disease.

Pollak MR.

Semin Nephrol. 2017 Nov;37(6):489. doi: 10.1016/j.semnephrol.2017.07.001. No abstract available.

PMID:
29110755
49.

Menstrual cycle characteristics and steroid hormone, prolactin, and growth factor levels in premenopausal women.

Farland LV, Mu F, Eliassen AH, Hankinson SE, Tworoger SS, Barbieri RL, Dowsett M, Pollak MN, Missmer SA.

Cancer Causes Control. 2017 Dec;28(12):1441-1452. doi: 10.1007/s10552-017-0971-2. Epub 2017 Oct 31.

50.

The Association Between IGF-I and IGFBP-3 and Incident Diabetes in an Older Population of Men and Women in the Cardiovascular Health Study.

Aneke-Nash CS, Xue X, Qi Q, Biggs ML, Cappola A, Kuller L, Pollak M, Psaty BM, Siscovick D, Mukamal K, Strickler HD, Kaplan RC.

J Clin Endocrinol Metab. 2017 Dec 1;102(12):4541-4547. doi: 10.1210/jc.2017-01273.

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