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Differential Effect of Demographics, Processing Speed, and Depression on Cognitive Function in 755 Non-demented Community-dwelling Elderly Individuals.

Mougias A, Christidi F, Synetou M, Kotrotsou I, Valkimadi P, Politis A.

Cogn Behav Neurol. 2019 Dec;32(4):236-246. doi: 10.1097/WNN.0000000000000211.


Unmet Needs in Pharmacological Treatment of Apathy in Alzheimer's Disease: A Systematic Review.

Theleritis CG, Siarkos KT, Politis AM.

Front Pharmacol. 2019 Oct 4;10:1108. doi: 10.3389/fphar.2019.01108. eCollection 2019.


Evidence-based systematic review of cognitive rehabilitation, emotional, and family treatment studies for children with acquired brain injury literature: From 2006 to 2017.

Laatsch L, Dodd J, Brown T, Ciccia A, Connor F, Davis K, Doherty M, Linden M, Locascio G, Lundine J, Murphy S, Nagele D, Niemeier J, Politis A, Rode C, Slomine B, Smetana R, Yaeger L.

Neuropsychol Rehabil. 2019 Oct 31:1-36. doi: 10.1080/09602011.2019.1678490. [Epub ahead of print]


Differential Expression of Apoptotic and Low-Grade Inflammatory Markers in Alzheimer Disease Compared to Diabetes Mellitus Type 1 and 2.

Alexandraki KI, Apostolopoulos NV, Adamopoulos C, Stamouli E, Dalagiorgou G, Papaioannou TG, Analitis A, Karamanou M, Makrilakis K, Politis A, Piperi C.

J Appl Lab Med. 2019 May;3(6):1003-1013. doi: 10.1373/jalm.2018.027623. Epub 2018 Dec 20.


Specific Residues in a Purine Transporter Are Critical for Dimerization, ER Exit, and Function.

Kourkoulou A, Grevias P, Lambrinidis G, Pyle E, Dionysopoulou M, Politis A, Mikros E, Byrne B, Diallinas G.

Genetics. 2019 Dec;213(4):1357-1372. doi: 10.1534/genetics.119.302566. Epub 2019 Oct 14.


Integrating hydrogen-deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins.

Martens C, Shekhar M, Lau AM, Tajkhorshid E, Politis A.

Nat Protoc. 2019 Nov;14(11):3183-3204. doi: 10.1038/s41596-019-0219-6. Epub 2019 Oct 11.


Psychiatric disorders and SLC6A4 gene variants: possible effects on alcohol dependence and alzheimer's disease.

Calabrò M, Mandelli L, Crisafulli C, Porcelli S, Albani D, Politis A, Papadimitriou GN, Di Nicola M, Janiri L, Colombo R, Martinotti G, Bellomo A, Vieta E, Bonassi S, Frustaci A, Ducci G, Landi S, Boccia S, Serretti A.

Mol Biol Rep. 2019 Oct 8. doi: 10.1007/s11033-019-05119-5. [Epub ahead of print]


Toward a Sequential Strategy for Diagnosing Neurocognitive Disorders: A Consensus from the "Act On Dementia" European Joint Action.

Krolak-Salmon P, Maillet A, Vanacore N, Selbaek G, Rejdak K, Traykov L, Politis A, Georges J, Borson S, Leperre-Desplanques A.

J Alzheimers Dis. 2019;72(2):363-372. doi: 10.3233/JAD-190461.


Mammary Defences and Immunity against Mastitis in Sheep.

Katsafadou AI, Politis AP, Mavrogianni VS, Barbagianni MS, Vasileiou NGC, Fthenakis GC, Fragkou IA.

Animals (Basel). 2019 Sep 26;9(10). pii: E726. doi: 10.3390/ani9100726. Review.


Protein-Lipid Interactions Stabilize the Oligomeric State of BOR1p from Saccharomyces cerevisiae.

Pyle E, Guo C, Hofmann T, Schmidt C, Ribiero O, Politis A, Byrne B.

Anal Chem. 2019 Oct 15;91(20):13071-13079. doi: 10.1021/acs.analchem.9b03271. Epub 2019 Sep 25.


Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.

Faull SV, Lau AMC, Martens C, Ahdash Z, Hansen K, Yebenes H, Schmidt C, Beuron F, Cronin NB, Morris EP, Politis A.

Nat Commun. 2019 Aug 23;10(1):3814. doi: 10.1038/s41467-019-11772-y.


[The effect of physical activity on dementia].

Kouloutbani K, Karteroliotis K, Politis A.

Psychiatriki. 2019 Apr-Jun;30(2):142-155. doi: 10.22365/jpsych.2019.302.142. Greek, Modern.


HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon.

Ahdash Z, Pyle E, Allen WJ, Corey RA, Collinson I, Politis A.

Elife. 2019 Jul 10;8. pii: e47402. doi: 10.7554/eLife.47402.


Alzheimer's Disease and Neurotransmission Gene Variants: Focus on Their Effects on Psychiatric Comorbidities and Inflammatory Parameters.

Porcelli S, Calabrò M, Crisafulli C, Politis A, Liappas I, Albani D, Raimondi I, Forloni G, Benedetti F, Papadimitriou GN, Serretti A.

Neuropsychobiology. 2019;78(2):79-85. doi: 10.1159/000497164. Epub 2019 May 16.


Gender differences of patients at-risk for psychosis regarding symptomatology, drug use, comorbidity and functioning - Results from the EU-GEI study.

Menghini-Müller S, Studerus E, Ittig S, Heitz U, Egloff L, Andreou C, Valmaggia LR, Kempton MJ, van der Gaag M, de Haan L, Nelson B, Barrantes-Vidal N, Nordentoft M, Ruhrmann S, Sachs G, Rutten BP, Os JV, Riecher-Rössler A; EU-GEI High Risk Study Group, McGuire P, Valmaggia LR, Kempton MJ, Calem M, Tognin S, Modinos G, de Haan L, van der Gaag M, Velthorst E, Kraan TC, van Dam DS, Burger N, Nelson B, McGorry P, Amminger GP, Pantelis C, Politis A, Goodall J, Riecher-Rössler A, Borgwardt S, Rapp C, Ittig S, Studerus E, Smieskova R, Bressan R, Gadelha A, Brietzke E, Asevedo G, Asevedo E, Zugman A, Barrantes-Vidal N, Domínguez-Martínez T, Racioppi A, Cristóbal-Narváez P, Kwapil TR, Monsonet M, Kazes M, Daban C, Bourgin J, Gay O, Mam-Lam-Fook C, Krebs MO, Nordholm D, Randers L, Krakauer K, Glenthøj L, Glenthøj B, Nordentoft M, Ruhrmann S, Gebhard D, Arnhold J, Klosterkötter J, Sachs G, Lasser I, Winklbaur B, Delespaul PA, Rutten BP, van Os J.

Eur Psychiatry. 2019 Jun;59:52-59. doi: 10.1016/j.eurpsy.2019.04.007. Epub 2019 May 7.


Plasma Levels of Soluble AβPPβ as a Biomarker for Alzheimer's Disease with Dementia.

Alexopoulos P, Thierjung N, Economou P, Werle L, Buhl F, Kagerbauer S, Papanastasiou AD, Grimmer T, Gourzis P, Berthele A, Hemmer B, Kübler H, Martin J, Politis A, Perneczky R.

J Alzheimers Dis. 2019;69(1):83-90. doi: 10.3233/JAD-181088.


Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry.

Lau AMC, Ahdash Z, Martens C, Politis A.

Bioinformatics. 2019 Sep 1;35(17):3171-3173. doi: 10.1093/bioinformatics/btz022.


ATP-induced asymmetric pre-protein folding as a driver of protein translocation through the Sec machinery.

Corey RA, Ahdash Z, Shah A, Pyle E, Allen WJ, Fessl T, Lovett JE, Politis A, Collinson I.

Elife. 2019 Jan 2;8. pii: e41803. doi: 10.7554/eLife.41803.


S100B Levels in Patients with Type 2 Diabetes Mellitus and Co-Occurring Depressive Symptoms.

Katsanou P, Tentolouris N, Perrea D, Katsanos S, Ntova V, Antrian V, Konstantopoulos P, Politis A.

Depress Res Treat. 2018 Nov 18;2018:5304759. doi: 10.1155/2018/5304759. eCollection 2018.


Native mass spectrometry goes more native: investigation of membrane protein complexes directly from SMALPs.

Hellwig N, Peetz O, Ahdash Z, Tascón I, Booth PJ, Mikusevic V, Diskowski M, Politis A, Hellmich Y, Hänelt I, Reading E, Morgner N.

Chem Commun (Camb). 2018 Dec 4;54(97):13702-13705. doi: 10.1039/c8cc06284f.


A Mass-Spectrometry-Based Modelling Workflow for Accurate Prediction of IgG Antibody Conformations in the Gas Phase.

Hansen K, Lau AM, Giles K, McDonnell JM, Struwe WB, Sutton BJ, Politis A.

Angew Chem Int Ed Engl. 2018 Dec 21;57(52):17194-17199. doi: 10.1002/anie.201812018. Epub 2018 Nov 27.


Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry.

Ahdash Z, Lau AM, Martens C, Politis A.

J Vis Exp. 2018 Oct 15;(140). doi: 10.3791/57966.


POPPeT: a New Method to Predict the Protection Factor of Backbone Amide Hydrogens.

Claesen J, Politis A.

J Am Soc Mass Spectrom. 2019 Jan;30(1):67-76. doi: 10.1007/s13361-018-2068-x. Epub 2018 Oct 18. Erratum in: J Am Soc Mass Spectrom. 2019 Feb 11;:.


Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.

Pernigo S, Chegkazi MS, Yip YY, Treacy C, Glorani G, Hansen K, Politis A, Bui S, Dodding MP, Steiner RA.

Elife. 2018 Oct 15;7. pii: e38362. doi: 10.7554/eLife.38362.


Direct protein-lipid interactions shape the conformational landscape of secondary transporters.

Martens C, Shekhar M, Borysik AJ, Lau AM, Reading E, Tajkhorshid E, Booth PJ, Politis A.

Nat Commun. 2018 Oct 8;9(1):4151. doi: 10.1038/s41467-018-06704-1.


Specific cardiolipin-SecY interactions are required for proton-motive force stimulation of protein secretion.

Corey RA, Pyle E, Allen WJ, Watkins DW, Casiraghi M, Miroux B, Arechaga I, Politis A, Collinson I.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):7967-7972. doi: 10.1073/pnas.1721536115. Epub 2018 Jul 16.


Patient- and Caregiver-Related Factors Associated with Caregiver Assessed Global Deterioration Scale Scoring in Demented Patients.

Mougias AA, Christidi F, Kontogianni E, Skaltsounaki E, Politis A, Politis A.

Curr Gerontol Geriatr Res. 2018 Jun 4;2018:9396160. doi: 10.1155/2018/9396160. eCollection 2018.


Extensive countrywide field investigation of subclinical mastitis in sheep in Greece.

Vasileiou NGC, Cripps PJ, Ioannidi KS, Chatzopoulos DC, Gougoulis DA, Sarrou S, Orfanou DC, Politis AP, Gonzalez-Valerio TC, Argyros S, Mavrogianni VS, Petinaki E, Fthenakis GC.

J Dairy Sci. 2018 Aug;101(8):7297-7310. doi: 10.3168/jds.2017-14075. Epub 2018 May 30.


Dealing with severe dementia in clinical practice: A validity and reliability study of Severe Mini-Mental State Examination in Greek population.

Mougias AA, Christidi F, Kiosterakis G, Messinis L, Politis A.

Int J Geriatr Psychiatry. 2018 Jun 1. doi: 10.1002/gps.4915. [Epub ahead of print] No abstract available.


Cerebrospinal Fluid BACE1 Activity and sAβPPβ as Biomarker Candidates of Alzheimer's Disease.

Alexopoulos P, Thierjung N, Grimmer T, Ortner M, Economou P, Assimakopoulos K, Gourzis P, Politis A, Perneczky R; The Alzheimer’s Disease Neuroimaging Initiative.

Dement Geriatr Cogn Disord. 2018;45(3-4):152-161. doi: 10.1159/000488481. Epub 2018 May 22.


Structural Lipids Enable the Formation of Functional Oligomers of the Eukaryotic Purine Symporter UapA.

Pyle E, Kalli AC, Amillis S, Hall Z, Lau AM, Hanyaloglu AC, Diallinas G, Byrne B, Politis A.

Cell Chem Biol. 2018 Jul 19;25(7):840-848.e4. doi: 10.1016/j.chembiol.2018.03.011. Epub 2018 Apr 19.


Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease.

Kokras N, Stamouli E, Sotiropoulos I, Katirtzoglou EA, Siarkos KT, Dalagiorgou G, Alexandraki KI, Coulocheri S, Piperi C, Politis AM.

J Clin Psychopharmacol. 2018 Apr;38(2):138-143. doi: 10.1097/JCP.0000000000000840.


Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies.

Haupt C, Hofmann T, Wittig S, Kostmann S, Politis A, Schmidt C.

J Vis Exp. 2017 Nov 28;(129). doi: 10.3791/56747.


Mechanistic insight into the assembly of the HerA-NurA helicase-nuclease DNA end resection complex.

Ahdash Z, Lau AM, Byrne RT, Lammens K, Stüetzer A, Urlaub H, Booth PJ, Reading E, Hopfner KP, Politis A.

Nucleic Acids Res. 2017 Nov 16;45(20):12025-12038. doi: 10.1093/nar/gkx890.


Fluid biomarker agreement and interrelation in dementia due to Alzheimer's disease.

Alexopoulos P, Roesler J, Werle L, Thierjung N, Lentzari I, Ortner M, Grimmer T, Laskaris N, Politis A, Gourzis P, Kurz A, Perneczky R; Alzheimer’s Disease Neuroimaging Initiative.

J Neural Transm (Vienna). 2018 Feb;125(2):193-201. doi: 10.1007/s00702-017-1810-z. Epub 2017 Nov 15.


Assessing depression in Greek dementia patients: Which scale to use?

Mougias AA, Politis A, Mougias MA, Beratis IN, Skapinakis P, Armata C, Mavreas VG.

Psychiatriki. 2017 Jul-Sep;28(3):203-210. doi: 10.22365/jpsych.2017.283.203.


Interrogating Membrane Protein Conformational Dynamics within Native Lipid Compositions.

Reading E, Hall Z, Martens C, Haghighi T, Findlay H, Ahdash Z, Politis A, Booth PJ.

Angew Chem Int Ed Engl. 2017 Dec 4;56(49):15654-15657. doi: 10.1002/anie.201709657. Epub 2017 Nov 8.


A systematic review of non-pharmacological treatments for apathy in dementia.

Theleritis C, Siarkos K, Politis AA, Katirtzoglou E, Politis A.

Int J Geriatr Psychiatry. 2018 Feb;33(2):e177-e192. doi: 10.1002/gps.4783. Epub 2017 Sep 29.


Recommendations for the Use of Serious Games in Neurodegenerative Disorders: 2016 Delphi Panel.

Manera V, Ben-Sadoun G, Aalbers T, Agopyan H, Askenazy F, Benoit M, Bensamoun D, Bourgeois J, Bredin J, Bremond F, Crispim-Junior C, David R, De Schutter B, Ettore E, Fairchild J, Foulon P, Gazzaley A, Gros A, Hun S, Knoefel F, Olde Rikkert M, Phan Tran MK, Politis A, Rigaud AS, Sacco G, Serret S, Thümmler S, Welter ML, Robert P.

Front Psychol. 2017 Jul 25;8:1243. doi: 10.3389/fpsyg.2017.01243. eCollection 2017.


Detection of text-based social cues in adults with traumatic brain injury.

Turkstra LS, Duff MC, Politis AM, Mutlu B.

Neuropsychol Rehabil. 2019 Jun;29(5):789-803. doi: 10.1080/09602011.2017.1333012. Epub 2017 Jun 8.


Structural characterisation of medically relevant protein assemblies by integrating mass spectrometry with computational modelling.

Politis A, Schmidt C.

J Proteomics. 2018 Mar 20;175:34-41. doi: 10.1016/j.jprot.2017.04.019. Epub 2017 Apr 28. Review.


Two Versus One High-Frequency Repetitive Transcranial Magnetic Stimulation Session per Day for Treatment-Resistant Depression: A Randomized Sham-Controlled Trial. Response to Andrade and Colleagues.

Theleritis C, Sakkas P, Paparrigopoulos T, Vitoratou S, Tzavara C, Bonaccorso S, Politis A, Soldatos CR, Psarros C.

J ECT. 2017 Jun;33(2):143. doi: 10.1097/YCT.0000000000000412. No abstract available.


Pharmacological and Nonpharmacological Treatment for Apathy in Alzheimer Disease : A systematic review across modalities

Theleritis C, Siarkos K, Katirtzoglou E, Politis A.

J Geriatr Psychiatry Neurol. 2017 Jan;30(1):26-49. doi: 10.1177/0891988716678684. Review.


Surface Accessibility and Dynamics of Macromolecular Assemblies Probed by Covalent Labeling Mass Spectrometry and Integrative Modeling.

Schmidt C, Macpherson JA, Lau AM, Tan KW, Fraternali F, Politis A.

Anal Chem. 2017 Feb 7;89(3):1459-1468. doi: 10.1021/acs.analchem.6b02875. Epub 2017 Jan 18.


[Pro-inflammatory cytokines in Alzheimer's disease].

Stamouli EC, Politis AM.

Psychiatriki. 2016 Oct-Dec;27(4):264-275. doi: 10.22365/jpsych.2016.274.264. Review. Greek, Modern.


Two Versus One High-Frequency Repetitive Transcranial Magnetic Stimulation Session per Day for Treatment-Resistant Depression: A Randomized Sham-Controlled Trial.

Theleritis C, Sakkas P, Paparrigopoulos T, Vitoratou S, Tzavara C, Bonaccorso S, Politis A, Soldatos CR, Psarros C.

J ECT. 2017 Sep;33(3):190-197. doi: 10.1097/YCT.0000000000000387.


Corrigendum to 'Role of neurodevelopment involved genes in psychiatric comorbidities and modulation of inflammatory processes in Alzheimer's disease' [J. Neurol. Sci. 370 (November 2016) 162-166].

Porcelli S, Crisafulli C, Donato L, Calabrò M, Politis A, Liappas I, Albani D, Atti AR, Salfi R, Raimondi I, Forloni G, Papadimitriou GN, De Ronchi D, Serretti A.

J Neurol Sci. 2017 Jan 15;372:49. doi: 10.1016/j.jns.2016.11.031. Epub 2016 Nov 19. No abstract available.


Role of neurodevelopment involved genes in psychiatric comorbidities and modulation of inflammatory processes in Alzheimer's disease.

Porcelli S, Crisafulli C, Donato L, Calabrò M, Politis A, Liappas I, Albani D, Atti AR, Salfi R, Raimondi I, Forloni G, Papadimitriou GN, De Ronchi D, Serretti A.

J Neurol Sci. 2016 Nov 15;370:162-166. doi: 10.1016/j.jns.2016.09.053. Epub 2016 Sep 28. Erratum in: J Neurol Sci. 2017 Jan 15;372:49.


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