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Items: 1 to 50 of 56

1.

Targeting bacterial biofilm: a new LecA multivalent ligand with inhibitory activity.

Palmioli A, Sperandeo P, Polissi A, Airoldi C.

Chembiochem. 2019 Jun 19. doi: 10.1002/cbic.201900383. [Epub ahead of print]

PMID:
31216375
2.

Lipopolysaccharide Biosynthesis and Transport to the Outer Membrane of Gram-Negative Bacteria.

Sperandeo P, Martorana AM, Polissi A.

Subcell Biochem. 2019;92:9-37. doi: 10.1007/978-3-030-18768-2_2.

PMID:
31214983
3.

Novel photo-thermally active polyvinyl alcohol-Prussian blue nanoparticles hydrogel films capable of eradicating bacteria and mitigating biofilms.

Borzenkov M, D'Alfonso L, Polissi A, Sperandeo P, Collini M, Dacarro G, Taglietti A, Chirico G, Pallavicini P.

Nanotechnology. 2019 Jul 19;30(29):295702. doi: 10.1088/1361-6528/ab15f9. Epub 2019 Apr 26.

PMID:
31025630
4.

Peptidoglycan Remodeling Enables Escherichia coli To Survive Severe Outer Membrane Assembly Defect.

Morè N, Martorana AM, Biboy J, Otten C, Winkle M, Serrano CKG, Montón Silva A, Atkinson L, Yau H, Breukink E, den Blaauwen T, Vollmer W, Polissi A.

MBio. 2019 Feb 5;10(1). pii: e02729-18. doi: 10.1128/mBio.02729-18.

5.

Pseudomonas aeruginosa LptE is crucial for LptD assembly, cell envelope integrity, antibiotic resistance and virulence.

Lo Sciuto A, Martorana AM, Fernández-Piñar R, Mancone C, Polissi A, Imperi F.

Virulence. 2018;9(1):1718-1733. doi: 10.1080/21505594.2018.1537730.

6.

Copper inhibits peptidoglycan LD-transpeptidases suppressing β-lactam resistance due to bypass of penicillin-binding proteins.

Peters K, Pazos M, Edoo Z, Hugonnet JE, Martorana AM, Polissi A, VanNieuwenhze MS, Arthur M, Vollmer W.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10786-10791. doi: 10.1073/pnas.1809285115. Epub 2018 Oct 1.

7.

Solid State NMR Studies of Intact Lipopolysaccharide Endotoxin.

Laguri C, Silipo A, Martorana AM, Schanda P, Marchetti R, Polissi A, Molinaro A, Simorre JP.

ACS Chem Biol. 2018 Aug 17;13(8):2106-2113. doi: 10.1021/acschembio.8b00271. Epub 2018 Jul 2.

PMID:
29965728
8.

Mutation and Suppressor Analysis of the Essential Lipopolysaccharide Transport Protein LptA Reveals Strategies To Overcome Severe Outer Membrane Permeability Defects in Escherichia coli.

Falchi FA, Maccagni EA, Puccio S, Peano C, De Castro C, Palmigiano A, Garozzo D, Martorana AM, Polissi A, Dehò G, Sperandeo P.

J Bacteriol. 2017 Dec 20;200(2). pii: e00487-17. doi: 10.1128/JB.00487-17. Print 2018 Jan 15.

9.

Skin infections are eliminated by cooperation of the fibrinolytic and innate immune systems.

Santus W, Barresi S, Mingozzi F, Broggi A, Orlandi I, Stamerra G, Vai M, Martorana AM, Polissi A, Köhler JR, Liu N, Zanoni I, Granucci F.

Sci Immunol. 2017 Sep 22;2(15). pii: eaan2725. doi: 10.1126/sciimmunol.aan2725.

10.

The lipopolysaccharide transport (Lpt) machinery: A nonconventional transporter for lipopolysaccharide assembly at the outer membrane of Gram-negative bacteria.

Sperandeo P, Martorana AM, Polissi A.

J Biol Chem. 2017 Nov 3;292(44):17981-17990. doi: 10.1074/jbc.R117.802512. Epub 2017 Sep 6. Review.

11.

Interaction of lipopolysaccharides at intermolecular sites of the periplasmic Lpt transport assembly.

Laguri C, Sperandeo P, Pounot K, Ayala I, Silipo A, Bougault CM, Molinaro A, Polissi A, Simorre JP.

Sci Rep. 2017 Aug 29;7(1):9715. doi: 10.1038/s41598-017-10136-0.

12.

Lipopolysaccharide biogenesis and transport at the outer membrane of Gram-negative bacteria.

Sperandeo P, Martorana AM, Polissi A.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Nov;1862(11):1451-1460. doi: 10.1016/j.bbalip.2016.10.006. Epub 2016 Oct 17. Review.

PMID:
27760389
13.

The Lack of the Essential LptC Protein in the Trans-Envelope Lipopolysaccharide Transport Machine Is Circumvented by Suppressor Mutations in LptF, an Inner Membrane Component of the Escherichia coli Transporter.

Benedet M, Falchi FA, Puccio S, Di Benedetto C, Peano C, Polissi A, Dehò G.

PLoS One. 2016 Aug 16;11(8):e0161354. doi: 10.1371/journal.pone.0161354. eCollection 2016.

14.

Differential Proteomics Based on Multidimensional Protein Identification Technology to Understand the Biogenesis of Outer Membrane of Escherichia coli.

Martorana AM, Motta S, Sperandeo P, Mauri P, Polissi A.

Methods Mol Biol. 2016;1440:57-70. doi: 10.1007/978-1-4939-3676-2_5.

PMID:
27311664
15.

Lipopolysaccharide Transport to the Cell Surface: New Insights in Assembly into the Outer Membrane.

Sperandeo P, Polissi A.

Structure. 2016 Jun 7;24(6):847-9. doi: 10.1016/j.str.2016.05.005.

16.

Functional Interaction between the Cytoplasmic ABC Protein LptB and the Inner Membrane LptC Protein, Components of the Lipopolysaccharide Transport Machinery in Escherichia coli.

Martorana AM, Benedet M, Maccagni EA, Sperandeo P, Villa R, Dehò G, Polissi A.

J Bacteriol. 2016 Jul 28;198(16):2192-203. doi: 10.1128/JB.00329-16. Print 2016 Aug 15.

17.

An induced folding process characterizes the partial-loss of function mutant LptAI36D in its interactions with ligands.

Santambrogio C, Sperandeo P, Barbieri F, Martorana AM, Polissi A, Grandori R.

Biochim Biophys Acta. 2015 Oct;1854(10 Pt A):1451-7. doi: 10.1016/j.bbapap.2015.06.013. Epub 2015 Jun 27.

PMID:
26123264
18.

Development of antibacterial quaternary ammonium silane coatings on polyurethane catheters.

Zanini S, Polissi A, Maccagni EA, Dell'Orto EC, Liberatore C, Riccardi C.

J Colloid Interface Sci. 2015 Aug 1;451:78-84. doi: 10.1016/j.jcis.2015.04.007. Epub 2015 Apr 9.

PMID:
25890115
19.

Crystal structure of LptH, the periplasmic component of the lipopolysaccharide transport machinery from Pseudomonas aeruginosa.

Bollati M, Villa R, Gourlay LJ, Benedet M, Dehò G, Polissi A, Barbiroli A, Martorana AM, Sperandeo P, Bolognesi M, Nardini M.

FEBS J. 2015 May;282(10):1980-97. doi: 10.1111/febs.13254. Epub 2015 Mar 20.

20.

Dissecting Escherichia coli outer membrane biogenesis using differential proteomics.

Martorana AM, Motta S, Di Silvestre D, Falchi F, Dehò G, Mauri P, Sperandeo P, Polissi A.

PLoS One. 2014 Jun 26;9(6):e100941. doi: 10.1371/journal.pone.0100941. eCollection 2014.

21.

Synthesis and biological evaluation of arabinose 5-phosphate mimics modified at position five.

Cipolla L, Airoldi C, Sperandeo P, Gianera S, Polissi A, Nicotra F, Gabrielli L.

Carbohydr Res. 2014 May 7;389:186-91. doi: 10.1016/j.carres.2014.01.004. Epub 2014 Jan 15.

PMID:
24680510
22.

Arabinose 5-phosphate isomerase as a target for antibacterial design: studies with substrate analogues and inhibitors.

Gabrielli L, Merlo S, Airoldi C, Sperandeo P, Gianera S, Polissi A, Nicotra F, Holler TP, Woodard RW, Cipolla L.

Bioorg Med Chem. 2014 Apr 15;22(8):2576-83. doi: 10.1016/j.bmc.2013.08.012. Epub 2013 Aug 11.

PMID:
24680056
23.

Functional characterization of E. coli LptC: interaction with LPS and a synthetic ligand.

Sestito SE, Sperandeo P, Santambrogio C, Ciaramelli C, Calabrese V, Rovati GE, Zambelloni L, Grandori R, Polissi A, Peri F.

Chembiochem. 2014 Mar 21;15(5):734-42.

PMID:
24677607
24.

The lipopolysaccharide export pathway in Escherichia coli: structure, organization and regulated assembly of the Lpt machinery.

Polissi A, Sperandeo P.

Mar Drugs. 2014 Feb 17;12(2):1023-42. doi: 10.3390/md12021023. Review.

25.

LptA assembles into rod-like oligomers involving disorder-to-order transitions.

Santambrogio C, Sperandeo P, Villa R, Sobott F, Polissi A, Grandori R.

J Am Soc Mass Spectrom. 2013 Oct;24(10):1593-602. doi: 10.1007/s13361-013-0687-9. Epub 2013 Jul 30.

PMID:
23897621
26.

The Escherichia coli Lpt transenvelope protein complex for lipopolysaccharide export is assembled via conserved structurally homologous domains.

Villa R, Martorana AM, Okuda S, Gourlay LJ, Nardini M, Sperandeo P, Dehò G, Bolognesi M, Kahne D, Polissi A.

J Bacteriol. 2013 Mar;195(5):1100-8. doi: 10.1128/JB.02057-12. Epub 2013 Jan 4.

27.

Complex transcriptional organization regulates an Escherichia coli locus implicated in lipopolysaccharide biogenesis.

Martorana AM, Sperandeo P, Polissi A, Dehò G.

Res Microbiol. 2011 Jun;162(5):470-82. doi: 10.1016/j.resmic.2011.03.007. Epub 2011 Mar 12.

PMID:
21402154
28.

Targeting bacterial membranes: identification of Pseudomonas aeruginosa D-arabinose-5P isomerase and NMR characterisation of its substrate recognition and binding properties.

Airoldi C, Sommaruga S, Merlo S, Sperandeo P, Cipolla L, Polissi A, Nicotra F.

Chembiochem. 2011 Mar 21;12(5):719-27. doi: 10.1002/cbic.201000754. Epub 2011 Feb 17.

PMID:
21337483
29.

New targets for antibacterial design: Kdo biosynthesis and LPS machinery transport to the cell surface.

Cipolla L, Polissi A, Airoldi C, Gabrielli L, Merlo S, Nicotra F.

Curr Med Chem. 2011;18(6):830-52. Review.

PMID:
21182480
30.

Site-specific mutation of Staphylococcus aureus VraS reveals a crucial role for the VraR-VraS sensor in the emergence of glycopeptide resistance.

Galbusera E, Renzoni A, Andrey DO, Monod A, Barras C, Tortora P, Polissi A, Kelley WL.

Antimicrob Agents Chemother. 2011 Mar;55(3):1008-20. doi: 10.1128/AAC.00720-10. Epub 2010 Dec 20.

31.

New insights into the Lpt machinery for lipopolysaccharide transport to the cell surface: LptA-LptC interaction and LptA stability as sensors of a properly assembled transenvelope complex.

Sperandeo P, Villa R, Martorana AM, Samalikova M, Grandori R, Dehò G, Polissi A.

J Bacteriol. 2011 Mar;193(5):1042-53. doi: 10.1128/JB.01037-10. Epub 2010 Dec 17.

32.

Probing the active site of the sugar isomerase domain from E. coli arabinose-5-phosphate isomerase via X-ray crystallography.

Gourlay LJ, Sommaruga S, Nardini M, Sperandeo P, Dehò G, Polissi A, Bolognesi M.

Protein Sci. 2010 Dec;19(12):2430-9. doi: 10.1002/pro.525.

33.

Targeting bacterial membranes: NMR spectroscopy characterization of substrate recognition and binding requirements of D-arabinose-5-phosphate isomerase.

Airoldi C, Sommaruga S, Merlo S, Sperandeo P, Cipolla L, Polissi A, Nicotra F.

Chemistry. 2010 Feb 8;16(6):1897-902. doi: 10.1002/chem.200902619.

PMID:
20039350
34.

Structure prediction and functional analysis of KdsD, an enzyme involved in lipopolysaccharide biosynthesis.

Sommaruga S, Gioia LD, Tortora P, Polissi A.

Biochem Biophys Res Commun. 2009 Oct 16;388(2):222-7. doi: 10.1016/j.bbrc.2009.07.154. Epub 2009 Aug 5.

PMID:
19664604
35.

The lipopolysaccharide transport system of Gram-negative bacteria.

Sperandeo P, Dehò G, Polissi A.

Biochim Biophys Acta. 2009 Jul;1791(7):594-602. doi: 10.1016/j.bbalip.2009.01.011. Epub 2009 Jan 29. Review.

PMID:
19416651
36.

The Kdo biosynthetic pathway toward OM biogenesis as target in antibacterial drug design and development.

Cipolla L, Polissi A, Airoldi C, Galliani P, Sperandeo P, Nicotra F.

Curr Drug Discov Technol. 2009 Mar;6(1):19-33. Review.

PMID:
19275539
37.

Nanostructured Ag(4)O(4) films with enhanced antibacterial activity.

Dellasega D, Facibeni A, Di Fonzo F, Bogana M, Polissi A, Conti C, Ducati C, Casari CS, Li Bassi A, Bottani CE.

Nanotechnology. 2008 Nov 26;19(47):475602. doi: 10.1088/0957-4484/19/47/475602. Epub 2008 Oct 30.

PMID:
21836277
38.

Novel structure of the conserved gram-negative lipopolysaccharide transport protein A and mutagenesis analysis.

Suits MD, Sperandeo P, Dehò G, Polissi A, Jia Z.

J Mol Biol. 2008 Jul 11;380(3):476-88. doi: 10.1016/j.jmb.2008.04.045. Epub 2008 Apr 26.

PMID:
18534617
39.

Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.

Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Dehò G, Silhavy TJ, Polissi A.

J Bacteriol. 2008 Jul;190(13):4460-9. doi: 10.1128/JB.00270-08. Epub 2008 Apr 18.

40.

Characterization of lptA and lptB, two essential genes implicated in lipopolysaccharide transport to the outer membrane of Escherichia coli.

Sperandeo P, Cescutti R, Villa R, Di Benedetto C, Candia D, Dehò G, Polissi A.

J Bacteriol. 2007 Jan;189(1):244-53. Epub 2006 Oct 20.

41.

Non-essential KDO biosynthesis and new essential cell envelope biogenesis genes in the Escherichia coli yrbG-yhbG locus.

Sperandeo P, Pozzi C, Dehò G, Polissi A.

Res Microbiol. 2006 Jul-Aug;157(6):547-58. Epub 2006 Feb 9.

PMID:
16765569
42.
43.

Scanning the Escherichia coli chromosome by random transposon mutagenesis and multiple phenotypic screening.

Serina S, Nozza F, Nicastro G, Faggioni F, Mottl H, Dehò G, Polissi A.

Res Microbiol. 2004 Oct;155(8):692-701.

PMID:
15380559
44.

Changes in Escherichia coli transcriptome during acclimatization at low temperature.

Polissi A, De Laurentis W, Zangrossi S, Briani F, Longhi V, Pesole G, Dehò G.

Res Microbiol. 2003 Oct;154(8):573-80.

PMID:
14527658
45.

Annotated draft genomic sequence from a Streptococcus pneumoniae type 19F clinical isolate.

Dopazo J, Mendoza A, Herrero J, Caldara F, Humbert Y, Friedli L, Guerrier M, Grand-Schenk E, Gandin C, de Francesco M, Polissi A, Buell G, Feger G, García E, Peitsch M, García-Bustos JF.

Microb Drug Resist. 2001 Summer;7(2):99-125.

PMID:
11442348
46.

The puzzle of zmpB and extensive chain formation, autolysis defect and non-translocation of choline-binding proteins in Streptococcus pneumoniae.

Bergé M, García P, Iannelli F, Prère MF, Granadel C, Polissi A, Claverys JP.

Mol Microbiol. 2001 Mar;39(6):1651-60.

47.

Global analysis of transcription kinetics during competence development in Streptococcus pneumoniae using high density DNA arrays.

Rimini R, Jansson B, Feger G, Roberts TC, de Francesco M, Gozzi A, Faggioni F, Domenici E, Wallace DM, Frandsen N, Polissi A.

Mol Microbiol. 2000 Jun;36(6):1279-92.

48.

Large-scale identification of virulence genes from Streptococcus pneumoniae.

Polissi A, Pontiggia A, Feger G, Altieri M, Mottl H, Ferrari L, Simon D.

Infect Immun. 1998 Dec;66(12):5620-9.

49.

Function of Escherichia coli MsbA, an essential ABC family transporter, in lipid A and phospholipid biosynthesis.

Zhou Z, White KA, Polissi A, Georgopoulos C, Raetz CR.

J Biol Chem. 1998 May 15;273(20):12466-75.

50.

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