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Items: 1 to 50 of 64

1.

An amino acid-based amphoteric liposomal delivery system for systemic administration of siRNA.

Adami RC, Seth S, Harvie P, Johns R, Fam R, Fosnaugh K, Zhu T, Farber K, McCutcheon M, Goodman TT, Liu Y, Chen Y, Kwang E, Templin MV, Severson G, Brown T, Vaish N, Chen F, Charmley P, Polisky B, Houston ME Jr.

Mol Ther. 2011 Jun;19(6):1141-51. doi: 10.1038/mt.2011.56. Epub 2011 Apr 19.

2.

RNAi-based therapeutics targeting survivin and PLK1 for treatment of bladder cancer.

Seth S, Matsui Y, Fosnaugh K, Liu Y, Vaish N, Adami R, Harvie P, Johns R, Severson G, Brown T, Takagi A, Bell S, Chen Y, Chen F, Zhu T, Fam R, Maciagiewicz I, Kwang E, McCutcheon M, Farber K, Charmley P, Houston ME Jr, So A, Templin MV, Polisky B.

Mol Ther. 2011 May;19(5):928-35. doi: 10.1038/mt.2011.21. Epub 2011 Mar 1.

3.

Improved specificity of gene silencing by siRNAs containing unlocked nucleobase analogs.

Vaish N, Chen F, Seth S, Fosnaugh K, Liu Y, Adami R, Brown T, Chen Y, Harvie P, Johns R, Severson G, Granger B, Charmley P, Houston M, Templin MV, Polisky B.

Nucleic Acids Res. 2011 Mar;39(5):1823-32. doi: 10.1093/nar/gkq961. Epub 2010 Nov 2.

4.

The siRNA sequence and guide strand overhangs are determinants of in vivo duration of silencing.

Strapps WR, Pickering V, Muiru GT, Rice J, Orsborn S, Polisky BA, Sachs A, Bartz SR.

Nucleic Acids Res. 2010 Aug;38(14):4788-97. doi: 10.1093/nar/gkq206. Epub 2010 Mar 31.

5.

Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes.

Saberi M, Bjelica D, Schenk S, Imamura T, Bandyopadhyay G, Li P, Jadhar V, Vargeese C, Wang W, Bowman K, Zhang Y, Polisky B, Olefsky JM.

Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1137-46. doi: 10.1152/ajpendo.00158.2009. Epub 2009 Aug 25.

6.

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi.

McBride JL, Boudreau RL, Harper SQ, Staber PD, Monteys AM, Martins I, Gilmore BL, Burstein H, Peluso RW, Polisky B, Carter BJ, Davidson BL.

Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5868-73. doi: 10.1073/pnas.0801775105. Epub 2008 Apr 8.

7.

Effect of chemically modified IL-13 short interfering RNA on development of airway hyperresponsiveness in mice.

Lively TN, Kossen K, Balhorn A, Koya T, Zinnen S, Takeda K, Lucas JJ, Polisky B, Richards IM, Gelfand EW.

J Allergy Clin Immunol. 2008 Jan;121(1):88-94. Epub 2007 Oct 22.

PMID:
17936889
8.

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs.

Morrissey DV, Lockridge JA, Shaw L, Blanchard K, Jensen K, Breen W, Hartsough K, Machemer L, Radka S, Jadhav V, Vaish N, Zinnen S, Vargeese C, Bowman K, Shaffer CS, Jeffs LB, Judge A, MacLachlan I, Polisky B.

Nat Biotechnol. 2005 Aug;23(8):1002-7. Epub 2005 Jul 24.

9.

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication.

Morrissey DV, Blanchard K, Shaw L, Jensen K, Lockridge JA, Dickinson B, McSwiggen JA, Vargeese C, Bowman K, Shaffer CS, Polisky BA, Zinnen S.

Hepatology. 2005 Jun;41(6):1349-56.

PMID:
15880588
10.

High-throughput ribozyme-based assays for detection of viral nucleic acids.

Kossen K, Vaish NK, Jadhav VR, Pasko C, Wang H, Jenison R, McSwiggen JA, Polisky B, Seiwert SD.

Chem Biol. 2004 Jun;11(6):807-15.

11.

An optical thin film assay incorporating rhinovirus protease inhibitors as detector reagents.

Ettinger A, Ostroff R, Rhihanek M, Dragovich PS, Zalman LS, Patick AK, Prins TJ, Fuhrman SA, Brown EL, Worland ST, Polisky B.

Antiviral Res. 2004 Mar;61(3):153-9.

PMID:
15168795
12.

Direct visualization of cystic fibrosis transmembrane regulator mutations in the clinical laboratory setting.

Strom CM, Clark DD, Hantash FM, Rea L, Anderson B, Maul D, Huang D, Traul D, Chen Tubman C, Garcia R, Hess PP, Wang H, Crossley B, Woodruff E, Chen R, Killeen M, Sun W, Beer J, Avens H, Polisky B, Jenison RD.

Clin Chem. 2004 May;50(5):836-45. Epub 2004 Mar 9.

PMID:
15010427
13.

Zeptomole detection of a viral nucleic acid using a target-activated ribozyme.

Vaish NK, Jadhav VR, Kossen K, Pasko C, Andrews LE, McSwiggen JA, Polisky B, Seiwert SD.

RNA. 2003 Sep;9(9):1058-72.

14.

In-process monitoring of protein purification with thin film silicon sensor technology.

Ettinger A, Ostroff R, Brien J, Polisky B.

Biotechniques. 2002 Apr;32(4):934-8.

15.

Use of a thin film biosensor for rapid visual detection of PCR products in a multiplex format.

Jenison R, Rihanek M, Polisky B.

Biosens Bioelectron. 2001 Dec;16(9-12):757-63.

PMID:
11679253
16.

Silicon-based biosensors for rapid detection of protein or nucleic acid targets.

Jenison R, La H, Haeberli A, Ostroff R, Polisky B.

Clin Chem. 2001 Oct;47(10):1894-900.

PMID:
11568116
17.

Rapid multiserotype detection of human rhinoviruses on optically coated silicon surfaces.

Ostroff R, Ettinger A, La H, Rihanek M, Zalman L, Meador J 3rd, Patick AK, Worland S, Polisky B.

J Clin Virol. 2001 May;21(2):105-17.

PMID:
11378491
18.

Interference-based detection of nucleic acid targets on optically coated silicon.

Jenison R, Yang S, Haeberli A, Polisky B.

Nat Biotechnol. 2001 Jan;19(1):62-5.

PMID:
11135554
19.

Thin film biosensor for rapid detection of mecA from methicillin-resistant staphylococcus aureus

Jenison R, Haeberli A, Yang S, Polisky B, Ostroff R.

Clin Chem. 2000 Sep;46(9):1501-4. No abstract available.

PMID:
10973902
20.

A heterologous, high-affinity RNA ligand for human immunodeficiency virus Gag protein has RNA packaging activity.

Clever JL, Taplitz RA, Lochrie MA, Polisky B, Parslow TG.

J Virol. 2000 Jan;74(1):541-6.

21.

Thin film biosensor for rapid visual detection of nucleic acid targets.

Ostroff RM, Hopkins D, Haeberli AB, Baouchi W, Polisky B.

Clin Chem. 1999 Sep;45(9):1659-64.

PMID:
10471680
22.
23.

In vitro selection of RNAs that bind to the human immunodeficiency virus type-1 gag polyprotein.

Lochrie MA, Waugh S, Pratt DG Jr, Clever J, Parslow TG, Polisky B.

Nucleic Acids Res. 1997 Jul 15;25(14):2902-10.

24.

A SELEX primer.

Fitzwater T, Polisky B.

Methods Enzymol. 1996;267:275-301. No abstract available.

PMID:
8743323
25.

Assessment of quantitative models for plasmid ColE1 copy number control.

Merlin S, Polisky B.

J Mol Biol. 1995 Apr 28;248(2):211-9.

PMID:
7537828
26.

Diversity of oligonucleotide functions.

Gold L, Polisky B, Uhlenbeck O, Yarus M.

Annu Rev Biochem. 1995;64:763-97. Review.

PMID:
7574500
27.
28.

High-resolution molecular discrimination by RNA.

Jenison RD, Gill SC, Pardi A, Polisky B.

Science. 1994 Mar 11;263(5152):1425-9.

PMID:
7510417
29.

DNA sequence requirements for the regulation of immobilization antigen A expression in Paramecium tetraurelia.

Martin LD, Pollack S, Preer JR Jr, Polisky B.

Dev Genet. 1994;15(5):443-51.

PMID:
7955570
30.

Analysis of establishment phase replication of the plasmid ColE1.

Merlin S, Polisky B.

J Mol Biol. 1993 Mar 5;230(1):137-50.

PMID:
7680724
31.
33.
34.

Permanent rescue of a non-Mendelian mutation of Paramecium by microinjection of specific DNA sequences.

Jessop-Murray H, Martin LD, Gilley D, Preer JR Jr, Polisky B.

Genetics. 1991 Nov;129(3):727-34.

35.

Mutants affecting processing of DNA in macronuclear development in paramecium.

Rudman B, Preer LB, Polisky B, Preer JR Jr.

Genetics. 1991 Sep;129(1):47-56.

36.

Multilevel regulation of surface antigen gene expression in Paramecium tetraurelia.

Gilley D, Rudman BM, Preer JR Jr, Polisky B.

Mol Cell Biol. 1990 Apr;10(4):1538-44.

37.

Effect of altering GATC sequences in the plasmid ColE1 primer promoter.

Patnaik PK, Merlin S, Polisky B.

J Bacteriol. 1990 Apr;172(4):1762-8.

39.

ColE1 replication control circuitry: sense from antisense.

Polisky B.

Cell. 1988 Dec 23;55(6):929-32. Review. No abstract available.

PMID:
2462471
40.
41.

Conditional high copy number ColE1 mutants: resistance to RNA1 inhibition in vivo and in vitro.

Fitzwater T, Zhang XY, Elble R, Polisky B.

EMBO J. 1988 Oct;7(10):3289-97.

42.

Transformation of Paramecium by microinjection of a cloned serotype gene.

Godiska R, Aufderheide KJ, Gilley D, Hendrie P, Fitzwater T, Preer LB, Polisky B, Preer JR Jr.

Proc Natl Acad Sci U S A. 1987 Nov;84(21):7590-4.

43.

Suppression of ColE1 RNA-RNA mismatch mutations in vivo by the ColE1 Rop protein.

Dooley TP, Polisky B.

Plasmid. 1987 Jul;18(1):24-34.

PMID:
2447599
44.

Isolation and characterization of mutants affecting functional domains of ColE1 RNAI.

Dooley TP, Tamm J, Polisky B.

J Mol Biol. 1985 Nov 5;186(1):87-96.

PMID:
2416940
45.
47.

Construction of Co1E1 RNA1 mutants and analysis of their function in vivo.

Polisky B, Tamm J, Fitzwater T.

Basic Life Sci. 1985;30:321-33.

PMID:
2409958
48.

High-level expression in Escherichia coli of calcium-binding domains of an embryonic sea urchin protein.

Muesing M, Carpenter CD, Klein WH, Polisky B.

Gene. 1984 Nov;31(1-3):155-64.

PMID:
6098520
49.

RNA1 is sufficient to mediate plasmid ColE1 incompatibility in vivo.

Fitzwater T, Tamm J, Polisky B.

J Mol Biol. 1984 May 25;175(3):409-17.

PMID:
6202877
50.

The molecular organization of the Antennapedia locus of Drosophila.

Scott MP, Weiner AJ, Hazelrigg TI, Polisky BA, Pirrotta V, Scalenghe F, Kaufman TC.

Cell. 1983 Dec;35(3 Pt 2):763-76.

PMID:
6418389

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