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Items: 1 to 50 of 115

1.

Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence.

Tomasetti C, Poling J, Roberts NJ, London NR Jr, Pittman ME, Haffner MC, Rizzo A, Baras A, Karim B, Kim A, Heaphy CM, Meeker AK, Hruban RH, Iacobuzio-Donahue CA, Vogelstein B.

Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20482-20488. doi: 10.1073/pnas.1905722116. Epub 2019 Sep 23.

PMID:
31548407
2.

Feasibility and effects of galantamine on cognition in humans with cannabis use disorder.

Sugarman DE, De Aquino JP, Poling J, Sofuoglu M.

Pharmacol Biochem Behav. 2019 Jun;181:86-92. doi: 10.1016/j.pbb.2019.05.004. Epub 2019 May 10.

PMID:
31082417
3.

Identification of Functional Protein Regions Through Chimeric Protein Construction.

Adrian-Segarra JM, Lörchner H, Braun T, Pöling J.

J Vis Exp. 2019 Jan 8;(143). doi: 10.3791/58786.

PMID:
30688304
4.

Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions.

Kuboki Y, Fischer CG, Beleva Guthrie V, Huang W, Yu J, Chianchiano P, Hosoda W, Zhang H, Zheng L, Shao X, Thompson ED, Waters K, Poling J, He J, Weiss MJ, Wolfgang CL, Goggins MG, Hruban RH, Roberts NJ, Karchin R, Wood LD.

J Pathol. 2019 Mar;247(3):347-356. doi: 10.1002/path.5194. Epub 2019 Jan 16.

PMID:
30430578
5.

The AB loop of oncostatin M (OSM) determines species-specific signaling in humans and mice.

Adrian-Segarra JM, Sreenivasan K, Gajawada P, Lörchner H, Braun T, Pöling J.

J Biol Chem. 2018 Dec 28;293(52):20181-20199. doi: 10.1074/jbc.RA118.004375. Epub 2018 Oct 29.

PMID:
30373773
6.

Reg proteins direct accumulation of functionally distinct macrophage subsets after myocardial infarction.

Lörchner H, Hou Y, Adrian-Segarra JM, Kulhei J, Detzer J, Günther S, Gajawada P, Warnecke H, Niessen HW, Pöling J, Braun T.

Cardiovasc Res. 2018 Oct 1;114(12):1667-1679. doi: 10.1093/cvr/cvy126.

PMID:
29850784
7.

Reg3β is associated with cardiac inflammation and provides prognostic information in patients with acute coronary syndrome.

Lörchner H, Widera C, Hou Y, Elsässer A, Warnecke H, Giannitsis E, Hulot JS, Braun T, Wollert KC, Pöling J.

Int J Cardiol. 2018 May 1;258:7-13. doi: 10.1016/j.ijcard.2018.01.043.

PMID:
29544958
8.

The AB loop and D-helix in binding site III of human Oncostatin M (OSM) are required for OSM receptor activation.

Adrian-Segarra JM, Schindler N, Gajawada P, Lörchner H, Braun T, Pöling J.

J Biol Chem. 2018 May 4;293(18):7017-7029. doi: 10.1074/jbc.RA118.001920. Epub 2018 Mar 6.

9.

Is a Pathological Complete Response Following Neoadjuvant Chemoradiation Associated With Prolonged Survival in Patients With Pancreatic Cancer?

He J, Blair AB, Groot VP, Javed AA, Burkhart RA, Gemenetzis G, Hruban RH, Waters KM, Poling J, Zheng L, Laheru D, Herman JM, Makary MA, Weiss MJ, Cameron JL, Wolfgang CL.

Ann Surg. 2018 Jul;268(1):1-8. doi: 10.1097/SLA.0000000000002672.

10.

A rare case of esophageal metastasis from pancreatic ductal adenocarcinoma: a case report and literature review.

Rosati LM, Kummerlowe MN, Poling J, Hacker-Prietz A, Narang AK, Shin EJ, Le DT, Fishman EK, Hruban RH, Yang SC, Weiss MJ, Herman JM.

Oncotarget. 2017 Jun 12;8(59):100942-100950. doi: 10.18632/oncotarget.18458. eCollection 2017 Nov 21.

11.

An unusual genomic variant of pancreatic ductal adenocarcinoma with an indolent clinical course.

Kohutek ZA, Rosati LM, Hong J, Poling J, Attiyeh MA, Makohon-Moore A, Herman JM, Iacobuzio-Donahue CA.

Cold Spring Harb Mol Case Stud. 2017 Jul 5;3(4). pii: a001701. doi: 10.1101/mcs.a001701. Print 2017 Jul.

12.

MYB Labeling by Immunohistochemistry Is More Sensitive and Specific for Breast Adenoid Cystic Carcinoma than MYB Labeling by FISH.

Poling JS, Yonescu R, Subhawong AP, Sharma R, Argani P, Ning Y, Cimino-Mathews A.

Am J Surg Pathol. 2017 Jul;41(7):973-979. doi: 10.1097/PAS.0000000000000878.

PMID:
28498281
13.

Carvedilol does not reduce cocaine use in methadone-maintained cocaine users.

Sofuoglu M, Poling J, Babuscio T, Gonsai K, Severino K, Nich C, Carroll KM.

J Subst Abuse Treat. 2017 Feb;73:63-69. doi: 10.1016/j.jsat.2016.11.005. Epub 2016 Nov 17.

14.

BRAF activates PAX3 to control muscle precursor cell migration during forelimb muscle development.

Shin J, Watanabe S, Hoelper S, Krüger M, Kostin S, Pöling J, Kubin T, Braun T.

Elife. 2016 Dec 1;5. pii: e18351. doi: 10.7554/eLife.18351.

15.

Intraductal Papillary Mucinous Neoplasm of the Pancreas Arising in the Setting of an Intermixed Acinar Cell Cystadenoma of the Pancreas: Report of a Rare Case.

Scott BB, Price TP, Callahan ZM, Poling JS, Lavu H.

Case Rep Pancreat Cancer. 2016 Dec 1;2(1):75-78. doi: 10.1089/crpc.2016.0018. eCollection 2016.

16.

Mutant p53 Together with TGFβ Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer.

Zhong Y, Macgregor-Das A, Saunders T, Whittle MC, Makohon-Moore A, Kohutek ZA, Poling J, Herbst BT, Javier BM, Cope L, Leach SD, Hingorani SR, Iacobuzio-Donahue CA.

Clin Cancer Res. 2017 Mar 15;23(6):1607-1620. doi: 10.1158/1078-0432.CCR-15-1615. Epub 2016 Sep 16.

17.

Mesenchymal stem cells attenuate inflammatory processes in the heart and lung via inhibition of TNF signaling.

Martire A, Bedada FB, Uchida S, Pöling J, Krüger M, Warnecke H, Richter M, Kubin T, Herold S, Braun T.

Basic Res Cardiol. 2016 Sep;111(5):54. doi: 10.1007/s00395-016-0573-2. Epub 2016 Jul 19.

18.

Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis.

Hackeng WM, Brosens LA, Poruk KE, Noë M, Hosoda W, Poling JS, Rizzo A, Campbell-Thompson M, Atkinson MA, Konukiewitz B, Klöppel G, Heaphy CM, Meeker AK, Wood LD.

Hum Pathol. 2016 Oct;56:93-100. doi: 10.1016/j.humpath.2016.06.006. Epub 2016 Jun 21.

PMID:
27342911
19.

Circulating Tumor Cell Phenotype Predicts Recurrence and Survival in Pancreatic Adenocarcinoma.

Poruk KE, Valero V 3rd, Saunders T, Blackford AL, Griffin JF, Poling J, Hruban RH, Anders RA, Herman J, Zheng L, Rasheed ZA, Laheru DA, Ahuja N, Weiss MJ, Cameron JL, Goggins M, Iacobuzio-Donahue CA, Wood LD, Wolfgang CL.

Ann Surg. 2016 Dec;264(6):1073-1081.

20.

Animal Models and "Omics" Technologies for Identification of Novel Biomarkers and Drug Targets to Prevent Heart Failure.

Hou Y, Adrian-Segarra JM, Richter M, Kubin N, Shin J, Werner I, Walther T, Schönburg M, Pöling J, Warnecke H, Braun T, Kostin S, Kubin T.

Biomed Res Int. 2015;2015:212910. doi: 10.1155/2015/212910. Epub 2015 Jul 7. Review.

21.

Myocardial healing requires Reg3β-dependent accumulation of macrophages in the ischemic heart.

Lörchner H, Pöling J, Gajawada P, Hou Y, Polyakova V, Kostin S, Adrian-Segarra JM, Boettger T, Wietelmann A, Warnecke H, Richter M, Kubin T, Braun T.

Nat Med. 2015 Apr;21(4):353-62. doi: 10.1038/nm.3816. Epub 2015 Mar 9.

PMID:
25751817
22.

Frozen section evaluation of breast carcinoma sentinel lymph nodes: a retrospective review of 1,940 cases.

Poling JS, Tsangaris TN, Argani P, Cimino-Mathews A.

Breast Cancer Res Treat. 2014 Nov;148(2):355-61. doi: 10.1007/s10549-014-3161-x. Epub 2014 Oct 16.

23.

Hospital admission for community-acquired pneumonia in a First Nations population.

Poling J, Kelly L, Chan C, Fisman D, Ulanova M.

Can J Rural Med. 2014 Fall;19(4):135-41.

PMID:
25291038
24.

A Possible Effect of Concentrated Oolong Tea Causing Transient Ischemic Attack-Like Symptoms.

Layher JW Jr, Poling JS, Ishihara M, Azadi P, Alvarez-Manilla G, Puett D.

Br J Med Med Res. 2013 Jul 18;3(4):2157-2172.

25.

Heterogeneity of pancreatic cancer metastases in a single patient revealed by quantitative proteomics.

Kim MS, Zhong Y, Yachida S, Rajeshkumar NV, Abel ML, Marimuthu A, Mudgal K, Hruban RH, Poling JS, Tyner JW, Maitra A, Iacobuzio-Donahue CA, Pandey A.

Mol Cell Proteomics. 2014 Nov;13(11):2803-11. doi: 10.1074/mcp.M114.038547. Epub 2014 Jun 3.

26.

Human papillomavirus (HPV) status of non-tobacco related squamous cell carcinomas of the lateral tongue.

Poling JS, Ma XJ, Bui S, Luo Y, Li R, Koch WM, Westra WH.

Oral Oncol. 2014 Apr;50(4):306-10. doi: 10.1016/j.oraloncology.2014.01.006. Epub 2014 Jan 30.

27.

Fetal death resulting from an isolated congenital partial pericardial defect.

Singer N, Aina-Mumuney A, Poling J, Burton EC.

Obstet Gynecol. 2014 Feb;123(2 Pt 2 Suppl 2):443-6. doi: 10.1097/AOG.0000000000000000.

PMID:
24413226
28.

Remodeling and dedifferentiation of adult cardiomyocytes during disease and regeneration.

Szibor M, Pöling J, Warnecke H, Kubin T, Braun T.

Cell Mol Life Sci. 2014 May;71(10):1907-16. doi: 10.1007/s00018-013-1535-6. Epub 2013 Dec 10. Review.

PMID:
24322910
29.

Therapeutic targeting of the oncostatin M receptor-β prevents inflammatory heart failure.

Pöling J, Gajawada P, Richter M, Lörchner H, Polyakova V, Kostin S, Shin J, Boettger T, Walther T, Rees W, Wietelmann A, Warnecke H, Kubin T, Braun T.

Basic Res Cardiol. 2014 Jan;109(1):396. doi: 10.1007/s00395-013-0396-3. Epub 2013 Nov 29.

PMID:
24292852
30.

The frequency of KRAS and BRAF mutations in intrahepatic cholangiocarcinomas and their correlation with clinical outcome.

Robertson S, Hyder O, Dodson R, Nayar SK, Poling J, Beierl K, Eshleman JR, Lin MT, Pawlik TM, Anders RA.

Hum Pathol. 2013 Dec;44(12):2768-73. doi: 10.1016/j.humpath.2013.07.026. Epub 2013 Oct 15.

31.

A complex interplay between personality domains, marital status and a variant in CHRNA5 on the risks of cocaine, nicotine dependences and cocaine-induced paranoia.

Zayats T, Yang BZ, Xie P, Poling J, Farrer LA, Gelernter J.

PLoS One. 2013;8(1):e49368. doi: 10.1371/journal.pone.0049368. Epub 2013 Jan 7.

32.

The Gne M712T mouse as a model for human glomerulopathy.

Kakani S, Yardeni T, Poling J, Ciccone C, Niethamer T, Klootwijk ED, Manoli I, Darvish D, Hoogstraten-Miller S, Zerfas P, Tian E, Ten Hagen KG, Kopp JB, Gahl WA, Huizing M.

Am J Pathol. 2012 Apr;180(4):1431-40. doi: 10.1016/j.ajpath.2011.12.023. Epub 2012 Feb 7.

33.

The Janus face of OSM-mediated cardiomyocyte dedifferentiation during cardiac repair and disease.

Pöling J, Gajawada P, Lörchner H, Polyakova V, Szibor M, Böttger T, Warnecke H, Kubin T, Braun T.

Cell Cycle. 2012 Feb 1;11(3):439-45. doi: 10.4161/cc.11.3.19024. Epub 2012 Feb 1.

PMID:
22262173
34.

Oncostatin M is a major mediator of cardiomyocyte dedifferentiation and remodeling.

Kubin T, Pöling J, Kostin S, Gajawada P, Hein S, Rees W, Wietelmann A, Tanaka M, Lörchner H, Schimanski S, Szibor M, Warnecke H, Braun T.

Cell Stem Cell. 2011 Nov 4;9(5):420-32. doi: 10.1016/j.stem.2011.08.013.

35.

Induction of smooth muscle cell migration during arteriogenesis is mediated by Rap2.

Pöling J, Szibor M, Schimanski S, Ingelmann ME, Rees W, Gajawada P, Kochfar Z, Lörchner H, Salwig I, Shin JY, Wiebe K, Kubin T, Warnecke H, Braun T.

Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2297-305. doi: 10.1161/ATVBAHA.111.232835. Epub 2011 Jul 7.

PMID:
21737786
36.

Pharmacologic correction of dominant-negative GH1 deficiency causing mutations.

Poling JS, Phillips JA 3rd, Cogan JD, Hamid R.

Clin Transl Sci. 2011 Jun;4(3):175-9. doi: 10.1111/j.1752-8062.2011.00290.x.

37.

Sertraline delays relapse in recently abstinent cocaine-dependent patients with depressive symptoms.

Oliveto A, Poling J, Mancino MJ, Williams DK, Thostenson J, Pruzinsky R, Gonsai K, Sofuoglu M, Gonzalez G, Tripathi S, Kosten TR.

Addiction. 2012 Jan;107(1):131-41. doi: 10.1111/j.1360-0443.2011.03552.x. Epub 2011 Oct 10.

38.

5-HTTLPR as a potential moderator of the effects of adverse childhood experiences on risk of antisocial personality disorder.

Douglas K, Chan G, Gelernter J, Arias AJ, Anton RF, Poling J, Farrer L, Kranzler HR.

Psychiatr Genet. 2011 Oct;21(5):240-8. doi: 10.1097/YPG.0b013e3283457c15.

39.

Galantamine improves sustained attention in chronic cocaine users.

Sofuoglu M, Waters AJ, Poling J, Carroll KM.

Exp Clin Psychopharmacol. 2011 Feb;19(1):11-9. doi: 10.1037/a0022213.

40.

The safety of modafinil in combination with oral ∆9-tetrahydrocannabinol in humans.

Sugarman DE, Poling J, Sofuoglu M.

Pharmacol Biochem Behav. 2011 Mar;98(1):94-100. doi: 10.1016/j.pbb.2010.12.013. Epub 2010 Dec 21.

41.

Randomized, double blind, placebo-controlled trial of disulfiram for the treatment of cocaine dependence in methadone-stabilized patients.

Oliveto A, Poling J, Mancino MJ, Feldman Z, Cubells JF, Pruzinsky R, Gonsai K, Cargile C, Sofuoglu M, Chopra MP, Gonzalez-Haddad G, Carroll KM, Kosten TR.

Drug Alcohol Depend. 2011 Jan 15;113(2-3):184-91. doi: 10.1016/j.drugalcdep.2010.07.022. Epub 2010 Sep 15.

42.

The safety and efficacy of varenicline in cocaine using smokers maintained on methadone: a pilot study.

Poling J, Rounsaville B, Gonsai K, Severino K, Sofuoglu M.

Am J Addict. 2010 Sep-Oct;19(5):401-8. doi: 10.1111/j.1521-0391.2010.00066.x.

43.

Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility.

Zhang H, Kranzler HR, Poling J, Gelernter J.

Neuropsychopharmacology. 2010 Oct;35(11):2211-24. doi: 10.1038/npp.2010.95. Epub 2010 Jul 14.

44.

Behavioral effects of gamma-hydroxybutyrate in humans.

Oliveto A, Gentry WB, Pruzinsky R, Gonsai K, Kosten TR, Martell B, Poling J.

Behav Pharmacol. 2010 Jul;21(4):332-42. doi: 10.1097/FBP.0b013e32833b3397.

45.

Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes.

Sherva R, Kranzler HR, Yu Y, Logue MW, Poling J, Arias AJ, Anton RF, Oslin D, Farrer LA, Gelernter J.

Neuropsychopharmacology. 2010 Aug;35(9):1921-31. doi: 10.1038/npp.2010.64. Epub 2010 May 19.

46.

Hereditary inclusion body myopathy: single patient response to GNE gene Lipoplex therapy.

Nemunaitis G, Maples PB, Jay C, Gahl WA, Huizing M, Poling J, Tong AW, Phadke AP, Pappen BO, Bedell C, Templeton NS, Kuhn J, Senzer N, Nemunaitis J.

J Gene Med. 2010 May;12(5):403-12. doi: 10.1002/jgm.1450.

PMID:
20440751
47.

Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder.

Xie P, Kranzler HR, Poling J, Stein MB, Anton RF, Farrer LA, Gelernter J.

Neuropsychopharmacology. 2010 Jul;35(8):1684-92. doi: 10.1038/npp.2010.37. Epub 2010 Apr 14.

48.

Effect of PTSD diagnosis and contingency management procedures on cocaine use in dually cocaine- and opioid-dependent individuals maintained on LAAM: a retrospective analysis.

Mancino MJ, McGaugh J, Feldman Z, Poling J, Oliveto A.

Am J Addict. 2010 Mar-Apr;19(2):169-77. doi: 10.1111/j.1521-0391.2009.00025.x.

49.

Confirmation and generalization of an alcohol-dependence locus on chromosome 10q.

Panhuysen CI, Kranzler HR, Yu Y, Weiss RD, Brady K, Poling J, Farrer LA, Gelernter J.

Neuropsychopharmacology. 2010 May;35(6):1325-32. doi: 10.1038/npp.2010.1. Epub 2010 Feb 10.

50.

Atomoxetine attenuates dextroamphetamine effects in humans.

Sofuoglu M, Poling J, Hill K, Kosten T.

Am J Drug Alcohol Abuse. 2009;35(6):412-6. doi: 10.3109/00952990903383961.

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